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The map label for this gene is fabZ [H]

Identifier: 119386613

GI number: 119386613

Start: 1042009

End: 1042554

Strand: Direct

Name: fabZ [H]

Synonym: Pden_3906

Alternate gene names: 119386613

Gene position: 1042009-1042554 (Clockwise)

Preceding gene: 119386612

Following gene: 119386614

Centisome position: 60.23

GC content: 63.55

Gene sequence:

>546_bases
TTGCCAAGTCCGCGCCCCGTTGCTAGGCAAATGAAAACATTCCAAGAGGACCGCATGGCCGCCGCCCCCAACGATGACCA
GACCGCCTATATCCCGCCGACCGAAGTCGATCTGGCGATGATCAAGCGCATCCTGCCGCATCGCTATCCCTTCCTGCTGG
TGGACCGCGTTCGCGACATCGTCCCGGCCGAAAGCTGCGTCGGCGTCAAGAACGTGACCTCGAACGAGCCGCATTTCGAA
GGGCATTTCCCGCAGGAGCCGGTCATGCCCGGCGTGCTGATCATCGAGGCCATGGCGCAATCGGCGGCGGTGCTGGTCGG
CGTCAGCCTGAATCTCGCCGACAAGGGCATGGGCACCTATTTCATGTCCATCGACAAATGCCGCTTCCGCCAGAAGGTGG
TGCCGGGCGACGTGCTGGAGCTGCACATGAAGACCCTGCGCGGCGGCGGCAAGATCTGGAAGTTCGAGGGCCGCGCCATC
GTCAACGGCCAGTTGGCCGCCGAGGCCGAGGTCATGGCCATGCTGAACCGTGGCGACAATGGCTGA

Upstream 100 bases:

>100_bases
TGCCGGGTTGGGCCTGGCTCGCGCTGATCGCCGGGCTGGCGGTGGCGGGCTGGCTGGCCGAGGGCCGCGGTCGGCTGCGC
AGCACCTGACACGGCGAAAC

Downstream 100 bases:

>100_bases
AACCCGCATCCACCCCTCGGCCGTCGTGGACCCCGCCGCGCAGGTCGGCGAGGGATGCGAGATCGGCCCGTTCTGCGTGA
TCGGTCCCGAGGTCGGCCTC

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 181; Mature: 180

Protein sequence:

>181_residues
MPSPRPVARQMKTFQEDRMAAAPNDDQTAYIPPTEVDLAMIKRILPHRYPFLLVDRVRDIVPAESCVGVKNVTSNEPHFE
GHFPQEPVMPGVLIIEAMAQSAAVLVGVSLNLADKGMGTYFMSIDKCRFRQKVVPGDVLELHMKTLRGGGKIWKFEGRAI
VNGQLAAEAEVMAMLNRGDNG

Sequences:

>Translated_181_residues
MPSPRPVARQMKTFQEDRMAAAPNDDQTAYIPPTEVDLAMIKRILPHRYPFLLVDRVRDIVPAESCVGVKNVTSNEPHFE
GHFPQEPVMPGVLIIEAMAQSAAVLVGVSLNLADKGMGTYFMSIDKCRFRQKVVPGDVLELHMKTLRGGGKIWKFEGRAI
VNGQLAAEAEVMAMLNRGDNG
>Mature_180_residues
PSPRPVARQMKTFQEDRMAAAPNDDQTAYIPPTEVDLAMIKRILPHRYPFLLVDRVRDIVPAESCVGVKNVTSNEPHFEG
HFPQEPVMPGVLIIEAMAQSAAVLVGVSLNLADKGMGTYFMSIDKCRFRQKVVPGDVLELHMKTLRGGGKIWKFEGRAIV
NGQLAAEAEVMAMLNRGDNG

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=139, Percent_Identity=45.3237410071942, Blast_Score=122, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 19987; Mature: 19855

Theoretical pI: Translated: 7.58; Mature: 7.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
7.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPRPVARQMKTFQEDRMAAAPNDDQTAYIPPTEVDLAMIKRILPHRYPFLLVDRVRDI
CCCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
VPAESCVGVKNVTSNEPHFEGHFPQEPVMPGVLIIEAMAQSAAVLVGVSLNLADKGMGTY
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEEEECCCCCCCCEE
FMSIDKCRFRQKVVPGDVLELHMKTLRGGGKIWKFEGRAIVNGQLAAEAEVMAMLNRGDN
EHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEECCCHHHHHHHHHHHHCCCC
G
C
>Mature Secondary Structure 
PSPRPVARQMKTFQEDRMAAAPNDDQTAYIPPTEVDLAMIKRILPHRYPFLLVDRVRDI
CCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHH
VPAESCVGVKNVTSNEPHFEGHFPQEPVMPGVLIIEAMAQSAAVLVGVSLNLADKGMGTY
CCHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCEEEEEEEECCCCCCCCEE
FMSIDKCRFRQKVVPGDVLELHMKTLRGGGKIWKFEGRAIVNGQLAAEAEVMAMLNRGDN
EHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCEEEECCCEEECCCHHHHHHHHHHHHCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA