Click here to switch to the map view.

The map label for this gene is hypB [H]

Identifier: 119385830

GI number: 119385830

Start: 291965

End: 292885

Strand: Direct

Name: hypB [H]

Synonym: Pden_3108

Alternate gene names: 119385830

Gene position: 291965-292885 (Clockwise)

Preceding gene: 119385829

Following gene: 119385831

Centisome position: 16.88

GC content: 65.15

Gene sequence:

>921_bases
ATGTGTGGGATTTGCGGTTGCGGCAGCACGGTGACGGTGGACGGGCGCGAGATCAGCCATGACGAGGCGCACCGGCTGGG
CCTGGCCCATGAGCACGCGCAGGATCACAGCCATGGCCATGGGCACAGCCATGCCGCGAATGGTCACGCGCATGACCATG
GTTCCGGCGATCACCACCACCATCATCACGACCATGCGCCGGGCCATGGTCACCATCACGACTACGGCGCGGGCGCGGCG
GGTCTGTCGGTGCCGGGCCTGACGCAGCAGCGGCTGATCGAGGTCGAGACCTCGCTTCTGGCCCGCAATGACGGGTTGGC
TGCGGGCAACCGGCGGGTACTTTCGGCGCTGCGAGCCTTTGCGGTCAACCTTGTCTCATCGCCCGGTTCTGGCAAGACCA
CGTTGCTGTGCCGGACCATCTCGATGCTGGAAGGCCAACCGCTGGCGGTGATCGAGGGCGACCAGCAGACCGAGAACGAT
GCCGACCGGATCCGCGCCACCGGCGCGCGGGCGGTGCAGGTCAATACCGGCAAGGGCTGCCATCTGGATGCGCAGATGGT
GGGCGGTGCGATGGATGCGCTGCGGCTGGAACCGGCCTCGCTGCTGTTCATCGAAAATGTCGGCAATCTGGTCTGCCCCG
CGGCTTTTGATCTGGGCGAGGATGCCAAGGTCGCGATCCTGTCGGTGACCGAGGGTGAAGACAAGCCCTTGAAATACCCT
GATATGTTTACGGCCGCAAGGCTTGCCATCCTGAACAAGATCGACCTTGCCCCCCATTGCGATGCCGATCCCGAGGTCTA
TGAGGCCAACCTGCGGCGGGTGAACCCCGGCATAGACATCCTGCGCCTTTCGGCCCGCACCGGCGAGGGGATGCAGGCCT
GGATCGACTGGCTGCGTGCCGGTCTGGCGACAAAGTCCTGA

Upstream 100 bases:

>100_bases
AATTGGACGACCGCCTGTCGCCCTGTCCCCTTTGTGGCGGTGGCAGGCTGATGCCCGAGACGGGGGACGAAATGCGGATC
AGGGATATGGAGGTGATCTG

Downstream 100 bases:

>100_bases
GCCATGCCCACGCCGCGCCCCTTTGTCCTGCTGGTGGATGACGAGCCGCATTCGCTTTCGGCGATGCGCATGGCGCTTGA
GGATGAGTTTGAAATCCTGA

Product: hydrogenase accessory protein HypB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MCGICGCGSTVTVDGREISHDEAHRLGLAHEHAQDHSHGHGHSHAANGHAHDHGSGDHHHHHHDHAPGHGHHHDYGAGAA
GLSVPGLTQQRLIEVETSLLARNDGLAAGNRRVLSALRAFAVNLVSSPGSGKTTLLCRTISMLEGQPLAVIEGDQQTEND
ADRIRATGARAVQVNTGKGCHLDAQMVGGAMDALRLEPASLLFIENVGNLVCPAAFDLGEDAKVAILSVTEGEDKPLKYP
DMFTAARLAILNKIDLAPHCDADPEVYEANLRRVNPGIDILRLSARTGEGMQAWIDWLRAGLATKS

Sequences:

>Translated_306_residues
MCGICGCGSTVTVDGREISHDEAHRLGLAHEHAQDHSHGHGHSHAANGHAHDHGSGDHHHHHHDHAPGHGHHHDYGAGAA
GLSVPGLTQQRLIEVETSLLARNDGLAAGNRRVLSALRAFAVNLVSSPGSGKTTLLCRTISMLEGQPLAVIEGDQQTEND
ADRIRATGARAVQVNTGKGCHLDAQMVGGAMDALRLEPASLLFIENVGNLVCPAAFDLGEDAKVAILSVTEGEDKPLKYP
DMFTAARLAILNKIDLAPHCDADPEVYEANLRRVNPGIDILRLSARTGEGMQAWIDWLRAGLATKS
>Mature_306_residues
MCGICGCGSTVTVDGREISHDEAHRLGLAHEHAQDHSHGHGHSHAANGHAHDHGSGDHHHHHHDHAPGHGHHHDYGAGAA
GLSVPGLTQQRLIEVETSLLARNDGLAAGNRRVLSALRAFAVNLVSSPGSGKTTLLCRTISMLEGQPLAVIEGDQQTEND
ADRIRATGARAVQVNTGKGCHLDAQMVGGAMDALRLEPASLLFIENVGNLVCPAAFDLGEDAKVAILSVTEGEDKPLKYP
DMFTAARLAILNKIDLAPHCDADPEVYEANLRRVNPGIDILRLSARTGEGMQAWIDWLRAGLATKS

Specific function: Could be involved in nickel binding and accumulation [H]

COG id: COG0378

COG function: function code OK; Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypB/hupM family [H]

Homologues:

Organism=Escherichia coli, GI1789082, Length=300, Percent_Identity=50.6666666666667, Blast_Score=270, Evalue=7e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR004392
- InterPro:   IPR012202 [H]

Pfam domain/function: PF02492 cobW [H]

EC number: NA

Molecular weight: Translated: 32488; Mature: 32488

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00028 ZINC_FINGER_C2H2_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCGICGCGSTVTVDGREISHDEAHRLGLAHEHAQDHSHGHGHSHAANGHAHDHGSGDHHH
CCCCCCCCCEEEECCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
HHHDHAPGHGHHHDYGAGAAGLSVPGLTQQRLIEVETSLLARNDGLAAGNRRVLSALRAF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AVNLVSSPGSGKTTLLCRTISMLEGQPLAVIEGDQQTENDADRIRATGARAVQVNTGKGC
HHHHHCCCCCCCEEEEEEEHHHHCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCC
HLDAQMVGGAMDALRLEPASLLFIENVGNLVCPAAFDLGEDAKVAILSVTEGEDKPLKYP
EEHHHHHCCHHHHHCCCCCCEEEEECCCCEECCHHCCCCCCCEEEEEEEECCCCCCCCCC
DMFTAARLAILNKIDLAPHCDADPEVYEANLRRVNPGIDILRLSARTGEGMQAWIDWLRA
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHH
GLATKS
HCCCCC
>Mature Secondary Structure
MCGICGCGSTVTVDGREISHDEAHRLGLAHEHAQDHSHGHGHSHAANGHAHDHGSGDHHH
CCCCCCCCCEEEECCCCCCCHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
HHHDHAPGHGHHHDYGAGAAGLSVPGLTQQRLIEVETSLLARNDGLAAGNRRVLSALRAF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
AVNLVSSPGSGKTTLLCRTISMLEGQPLAVIEGDQQTENDADRIRATGARAVQVNTGKGC
HHHHHCCCCCCCEEEEEEEHHHHCCCCEEEEECCCCCCCHHHHHHHCCCEEEEEECCCCC
HLDAQMVGGAMDALRLEPASLLFIENVGNLVCPAAFDLGEDAKVAILSVTEGEDKPLKYP
EEHHHHHCCHHHHHCCCCCCEEEEECCCCEECCHHCCCCCCCEEEEEEEECCCCCCCCCC
DMFTAARLAILNKIDLAPHCDADPEVYEANLRRVNPGIDILRLSARTGEGMQAWIDWLRA
CHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHH
GLATKS
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190; 2007559 [H]