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The map label for this gene is hypA

Identifier: 119385829

GI number: 119385829

Start: 291624

End: 291965

Strand: Direct

Name: hypA

Synonym: Pden_3107

Alternate gene names: 119385829

Gene position: 291624-291965 (Clockwise)

Preceding gene: 119385828

Following gene: 119385830

Centisome position: 16.86

GC content: 63.74

Gene sequence:

>342_bases
ATGCATGAGATGTCGCTTTGCGAAGGGATCCGCGGCATTGTCGAGGATCAGGCCCGCCGCCACGGTTTTTCCCGCGTGAC
CCGGATGCGGCTGGAAATCGGGCGCTTTGCCGGGGTGGAAAAGGCCGCGCTGAGCTTTGCCTTTGACGTGGTCATGCGCG
GCAGCCCGGCCGAGGGCGCGGTCCTGGAAATGATCGACCTGCCGGGCCGGGCAATGTGTTTCGACTGTGCCGAACAGGTG
GAATTGGACGACCGCCTGTCGCCCTGTCCCCTTTGTGGCGGTGGCAGGCTGATGCCCGAGACGGGGGACGAAATGCGGAT
CAGGGATATGGAGGTGATCTGA

Upstream 100 bases:

>100_bases
GCCAGCCTTGCGACACTTCCGCCAGACAAGGCTGATCGGGCGCCTTTGCTTGCCATGATCCTTGATCCCTGTATCCCTCT
GCATCTGGAGGCCGGACCCC

Downstream 100 bases:

>100_bases
TGTGTGGGATTTGCGGTTGCGGCAGCACGGTGACGGTGGACGGGCGCGAGATCAGCCATGACGAGGCGCACCGGCTGGGC
CTGGCCCATGAGCACGCGCA

Product: hydrogenase nickel insertion protein HypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGAVLEMIDLPGRAMCFDCAEQV
ELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI

Sequences:

>Translated_113_residues
MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGAVLEMIDLPGRAMCFDCAEQV
ELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI
>Mature_113_residues
MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGAVLEMIDLPGRAMCFDCAEQV
ELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI

Specific function: Probably plays a role in an hydrogenase nickel cofactor insertion step

COG id: COG0375

COG function: function code R; Zn finger protein HypA/HybF (possibly regulating hydrogenase expression)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypA/hybF family

Homologues:

Organism=Escherichia coli, GI1789365, Length=112, Percent_Identity=41.0714285714286, Blast_Score=105, Evalue=1e-24,
Organism=Escherichia coli, GI1789081, Length=113, Percent_Identity=39.8230088495575, Blast_Score=86, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HYPA_PARDP (A1B6P4)

Other databases:

- EMBL:   CP000490
- RefSeq:   YP_916884.1
- STRING:   A1B6P4
- GeneID:   4581671
- GenomeReviews:   CP000490_GR
- KEGG:   pde:Pden_3107
- eggNOG:   COG0375
- HOGENOM:   HBG688671
- OMA:   MHEMSLC
- PhylomeDB:   A1B6P4
- ProtClustDB:   CLSK841274
- HAMAP:   MF_00213
- InterPro:   IPR000688
- InterPro:   IPR020538
- TIGRFAMs:   TIGR00100

Pfam domain/function: PF01155 HypA

EC number: NA

Molecular weight: Translated: 12548; Mature: 12548

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: PS01249 HYPA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.4 %Cys     (Translated Protein)
8.0 %Met     (Translated Protein)
12.4 %Cys+Met (Translated Protein)
4.4 %Cys     (Mature Protein)
8.0 %Met     (Mature Protein)
12.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
VLEMIDLPGRAMCFDCAEQVELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI
EEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MHEMSLCEGIRGIVEDQARRHGFSRVTRMRLEIGRFAGVEKAALSFAFDVVMRGSPAEGA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCC
VLEMIDLPGRAMCFDCAEQVELDDRLSPCPLCGGGRLMPETGDEMRIRDMEVI
EEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA