Click here to switch to the map view.

The map label for this gene is nifU [H]

Identifier: 119358130

GI number: 119358130

Start: 2747534

End: 2748145

Strand: Reverse

Name: nifU [H]

Synonym: Cpha266_2362

Alternate gene names: 119358130

Gene position: 2748145-2747534 (Counterclockwise)

Preceding gene: 119358131

Following gene: 119358129

Centisome position: 87.69

GC content: 48.69

Gene sequence:

>612_bases
ATGCTACAAGCAGGTGAATGGGCATATACGGAAAAACTGAAGGAACACTTCATGAGCCCGAAAAATATATTACAGGGTGA
GAATACCGACGAATTTGACGGTGTCGGAATGGAGGGTAATTTGCAGTGCGGCGACCAGATGATGGTGGTCATCAAGGTTG
ATAAAGATAAAGAGGTTATCACGGATTGCCAGTGGAAGACCTACGGCTGCGCAAGCGCCATTGCAAGCACATCTATCTTG
TCCGAGATGGTCAAGGGCAGGACACTTGACGATGCATTCAATATCTCTCCCAAAGAGGTTGCCATGGAGCTTGGCGGTCT
GCCCGATCACAAAATTCACTGTTCCGTCCTTGGCGACAAGGCTCTGCGGGCAGCCATCAATGATTATTATTCCCGCAACG
ACATGCAGGACAAGGTTAAGCAGGCACAGGTGAAAATAGTCTGTCAGTGCATGAGCATCAGCGATCATGATATTGAGGAT
GCCGTTCTTGAAGGGGCGCGCACGTATTTCGAGTTGCAGGAACGAACCAAACTCGGAACGGTATGCGGCCAGTGCAAGGA
TGAAGCCGAATCATTGCTTGAAAAATTCAAGCATATTCATTTCGGAGCCTGA

Upstream 100 bases:

>100_bases
GAGAGCACGATGGAAGAGGTTGATTATGTGCTTGATGTTTTACCACGAACTATCGAACGAATCAGAAACATGTCTACGGC
ATACATAAAAGGAGGACTCC

Downstream 100 bases:

>100_bases
ACTGAACCCGATTCGTTGACCGTCGGTATATTTATTTACTGCCGGTTGGGATAACGGATCCATAACCGGGCGCAGAATGT
GTGCCTGGTTTTTTAAAGCC

Product: NifU domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MLQAGEWAYTEKLKEHFMSPKNILQGENTDEFDGVGMEGNLQCGDQMMVVIKVDKDKEVITDCQWKTYGCASAIASTSIL
SEMVKGRTLDDAFNISPKEVAMELGGLPDHKIHCSVLGDKALRAAINDYYSRNDMQDKVKQAQVKIVCQCMSISDHDIED
AVLEGARTYFELQERTKLGTVCGQCKDEAESLLEKFKHIHFGA

Sequences:

>Translated_203_residues
MLQAGEWAYTEKLKEHFMSPKNILQGENTDEFDGVGMEGNLQCGDQMMVVIKVDKDKEVITDCQWKTYGCASAIASTSIL
SEMVKGRTLDDAFNISPKEVAMELGGLPDHKIHCSVLGDKALRAAINDYYSRNDMQDKVKQAQVKIVCQCMSISDHDIED
AVLEGARTYFELQERTKLGTVCGQCKDEAESLLEKFKHIHFGA
>Mature_203_residues
MLQAGEWAYTEKLKEHFMSPKNILQGENTDEFDGVGMEGNLQCGDQMMVVIKVDKDKEVITDCQWKTYGCASAIASTSIL
SEMVKGRTLDDAFNISPKEVAMELGGLPDHKIHCSVLGDKALRAAINDYYSRNDMQDKVKQAQVKIVCQCMSISDHDIED
AVLEGARTYFELQERTKLGTVCGQCKDEAESLLEKFKHIHFGA

Specific function: Involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=128, Percent_Identity=41.40625, Blast_Score=101, Evalue=5e-22,
Organism=Homo sapiens, GI24307953, Length=115, Percent_Identity=42.6086956521739, Blast_Score=96, Evalue=2e-20,
Organism=Escherichia coli, GI1788878, Length=129, Percent_Identity=47.2868217054264, Blast_Score=117, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17543474, Length=124, Percent_Identity=40.3225806451613, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6325122, Length=126, Percent_Identity=44.4444444444444, Blast_Score=108, Evalue=4e-25,
Organism=Saccharomyces cerevisiae, GI6324800, Length=134, Percent_Identity=36.5671641791045, Blast_Score=102, Evalue=6e-23,
Organism=Drosophila melanogaster, GI21355597, Length=121, Percent_Identity=41.3223140495868, Blast_Score=100, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007419
- InterPro:   IPR016217
- InterPro:   IPR010238
- InterPro:   IPR001075
- InterPro:   IPR002871
- ProDom:   PD002830 [H]

Pfam domain/function: PF04324 Fer2_BFD; PF01106 NifU; PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 22677; Mature: 22677

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
8.4 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
8.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQAGEWAYTEKLKEHFMSPKNILQGENTDEFDGVGMEGNLQCGDQMMVVIKVDKDKEVI
CCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
TDCQWKTYGCASAIASTSILSEMVKGRTLDDAFNISPKEVAMELGGLPDHKIHCSVLGDK
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCCCCEEEEEEHHHH
ALRAAINDYYSRNDMQDKVKQAQVKIVCQCMSISDHDIEDAVLEGARTYFELQERTKLGT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VCGQCKDEAESLLEKFKHIHFGA
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLQAGEWAYTEKLKEHFMSPKNILQGENTDEFDGVGMEGNLQCGDQMMVVIKVDKDKEVI
CCCCCCHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHH
TDCQWKTYGCASAIASTSILSEMVKGRTLDDAFNISPKEVAMELGGLPDHKIHCSVLGDK
HCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHCCCCCCEEEEEEHHHH
ALRAAINDYYSRNDMQDKVKQAQVKIVCQCMSISDHDIEDAVLEGARTYFELQERTKLGT
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
VCGQCKDEAESLLEKFKHIHFGA
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2644218; 3040672; 7947754; 10819462 [H]