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The map label for this gene is menC [H]

Identifier: 119357884

GI number: 119357884

Start: 2425475

End: 2426548

Strand: Direct

Name: menC [H]

Synonym: Cpha266_2092

Alternate gene names: 119357884

Gene position: 2425475-2426548 (Clockwise)

Preceding gene: 119357883

Following gene: 119357885

Centisome position: 77.39

GC content: 51.96

Gene sequence:

>1074_bases
TTGAATGCGTCATTTTTACACCTTTACCGGTATAGCATCCCTTTCAATGAGCCGGTTACCGTAAGAAACCATCGGCTTCT
GAACAGAGAGGGGATAATTATCGCATTGAAGTCAAGCGACGGCGCGATGATTTCCTATGGCGAAATCGCGCCGTTGCCAG
GCCTGCATGAAGAGACGCTGCATATGGCTGAACATCAGTTTATGGAGTACATTTACAACCATAAGCTCAGCACGATCGAC
CTCCTCCCCGAAGGGCTCTTCCCTTCCGTAAAAACCGGCATTGAAATCGCGCTTTTCAACTTCAAGGCCGTCAATTCAGG
TATTCCGCCGTTTTTTTCTTCCCCCTCTCCGTCGGCAAGTCGGGTTCCGATCAACGCCCTGCTGGCCGGCGAGCGCGAAT
CGATCATAGTCCGGGCAGAGACCCTCTATAACCTCGGCTACCGGACGTTCAAACTCAAGGTAACGCCGAAAAACGCCGAA
CAGACTCTTGGTGTCATCAGGGAATTATCGCTGAAGTTCGGAGAAACCGTTGCGTTGCGCCTTGACGCAAACCAGTCGTT
TTCGCTCGATGAAGCGGTCGAGTTCAGCAAAAACATCATCAGGGACAATATCTCCTATATCGAAGAACCCTTGACGGATC
CGATACTCATCGGGGAGTTTCATGCCAGAACAGCAGTGCGCTCGGCACTTGATGAAACGCTCTGGCAGCAACCGTACCTG
ATGCGTTCGTTTCCCCCCGGCGCGTTGAAGGCTCTTGTTCTTAAACCAAACCGCCTTGGCGGAATAGTCGAAACGCTCCG
TTTAGCGCAGTATGCACGGGAAAACAACCTGCTTGCCGTTCTGAGTTCCGCATTCGAAAGCGGTATAAGTCTGAGTTTTT
ATGCATGGCTTGCCGCGCACACCAGCACGGAACCTGCTGCCTCGGGACTCGATACCGGACGTTATCTCGAGTATGATCTG
CTCGATCTCCCTTTCGGAAGTTCATCCGACACGCTCACGCCTCAGGAACTCTACTGGAATGGCCACAAGGTCGCAACCTC
GCACCTCAAGCCTTCATCAATATGGACATTATAA

Upstream 100 bases:

>100_bases
ACGCCACCATGCTCTACTATATGAGCGAAGAGGCTCAGGAGGGAAAAAATGCATTCGTCGAAAAAAGAAAGCCTGATTTC
ACTAAATTCCCGAAACGCCC

Downstream 100 bases:

>100_bases
ACCAGGCCGCTCTCCGGTTCGCCGATTCGCCTCTGCTTGTCACAAGGGAAAAAACACTCTCTTTCAGGGAGTGTTCTGTA
AAAGCCTCACAAATCGCCAA

Product: O-succinylbenzoate-CoA synthase

Products: NA

Alternate protein names: OSB synthase; OSBS; 4-(2'-carboxyphenyl)-4-oxybutyric acid synthase; o-succinylbenzoic acid synthase [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MNASFLHLYRYSIPFNEPVTVRNHRLLNREGIIIALKSSDGAMISYGEIAPLPGLHEETLHMAEHQFMEYIYNHKLSTID
LLPEGLFPSVKTGIEIALFNFKAVNSGIPPFFSSPSPSASRVPINALLAGERESIIVRAETLYNLGYRTFKLKVTPKNAE
QTLGVIRELSLKFGETVALRLDANQSFSLDEAVEFSKNIIRDNISYIEEPLTDPILIGEFHARTAVRSALDETLWQQPYL
MRSFPPGALKALVLKPNRLGGIVETLRLAQYARENNLLAVLSSAFESGISLSFYAWLAAHTSTEPAASGLDTGRYLEYDL
LDLPFGSSSDTLTPQELYWNGHKVATSHLKPSSIWTL

Sequences:

>Translated_357_residues
MNASFLHLYRYSIPFNEPVTVRNHRLLNREGIIIALKSSDGAMISYGEIAPLPGLHEETLHMAEHQFMEYIYNHKLSTID
LLPEGLFPSVKTGIEIALFNFKAVNSGIPPFFSSPSPSASRVPINALLAGERESIIVRAETLYNLGYRTFKLKVTPKNAE
QTLGVIRELSLKFGETVALRLDANQSFSLDEAVEFSKNIIRDNISYIEEPLTDPILIGEFHARTAVRSALDETLWQQPYL
MRSFPPGALKALVLKPNRLGGIVETLRLAQYARENNLLAVLSSAFESGISLSFYAWLAAHTSTEPAASGLDTGRYLEYDL
LDLPFGSSSDTLTPQELYWNGHKVATSHLKPSSIWTL
>Mature_357_residues
MNASFLHLYRYSIPFNEPVTVRNHRLLNREGIIIALKSSDGAMISYGEIAPLPGLHEETLHMAEHQFMEYIYNHKLSTID
LLPEGLFPSVKTGIEIALFNFKAVNSGIPPFFSSPSPSASRVPINALLAGERESIIVRAETLYNLGYRTFKLKVTPKNAE
QTLGVIRELSLKFGETVALRLDANQSFSLDEAVEFSKNIIRDNISYIEEPLTDPILIGEFHARTAVRSALDETLWQQPYL
MRSFPPGALKALVLKPNRLGGIVETLRLAQYARENNLLAVLSSAFESGISLSFYAWLAAHTSTEPAASGLDTGRYLEYDL
LDLPFGSSSDTLTPQELYWNGHKVATSHLKPSSIWTL

Specific function: Converts SHCHC to OSB [H]

COG id: COG1441

COG function: function code H; O-succinylbenzoate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mandelate racemase/muconate lactonizing enzyme family. MenC type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788596, Length=309, Percent_Identity=28.8025889967638, Blast_Score=103, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013342
- InterPro:   IPR010196 [H]

Pfam domain/function: PF01188 MR_MLE [H]

EC number: =4.2.1.113 [H]

Molecular weight: Translated: 39784; Mature: 39784

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00909 MR_MLE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNASFLHLYRYSIPFNEPVTVRNHRLLNREGIIIALKSSDGAMISYGEIAPLPGLHEETL
CCCCEEEEEEEECCCCCCEEECCCEEECCCCEEEEEECCCCCEEEECCCCCCCCCCHHHH
HMAEHQFMEYIYNHKLSTIDLLPEGLFPSVKTGIEIALFNFKAVNSGIPPFFSSPSPSAS
HHHHHHHHHHHHHCCCCEEECCCCCCCCCHHCCEEEEEEEEEECCCCCCCCCCCCCCCCC
RVPINALLAGERESIIVRAETLYNLGYRTFKLKVTPKNAEQTLGVIRELSLKFGETVALR
CCCCHHEECCCCCEEEEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEE
LDANQSFSLDEAVEFSKNIIRDNISYIEEPLTDPILIGEFHARTAVRSALDETLWQQPYL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCH
MRSFPPGALKALVLKPNRLGGIVETLRLAQYARENNLLAVLSSAFESGISLSFYAWLAAH
HHCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEHHC
TSTEPAASGLDTGRYLEYDLLDLPFGSSSDTLTPQELYWNGHKVATSHLKPSSIWTL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHEECCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MNASFLHLYRYSIPFNEPVTVRNHRLLNREGIIIALKSSDGAMISYGEIAPLPGLHEETL
CCCCEEEEEEEECCCCCCEEECCCEEECCCCEEEEEECCCCCEEEECCCCCCCCCCHHHH
HMAEHQFMEYIYNHKLSTIDLLPEGLFPSVKTGIEIALFNFKAVNSGIPPFFSSPSPSAS
HHHHHHHHHHHHHCCCCEEECCCCCCCCCHHCCEEEEEEEEEECCCCCCCCCCCCCCCCC
RVPINALLAGERESIIVRAETLYNLGYRTFKLKVTPKNAEQTLGVIRELSLKFGETVALR
CCCCHHEECCCCCEEEEEEHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEE
LDANQSFSLDEAVEFSKNIIRDNISYIEEPLTDPILIGEFHARTAVRSALDETLWQQPYL
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCH
MRSFPPGALKALVLKPNRLGGIVETLRLAQYARENNLLAVLSSAFESGISLSFYAWLAAH
HHCCCCHHHEEEEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEHHC
TSTEPAASGLDTGRYLEYDLLDLPFGSSSDTLTPQELYWNGHKVATSHLKPSSIWTL
CCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCHHHHEECCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]