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The map label for this gene is hflX [H]

Identifier: 119357534

GI number: 119357534

Start: 1962090

End: 1963394

Strand: Reverse

Name: hflX [H]

Synonym: Cpha266_1737

Alternate gene names: 119357534

Gene position: 1963394-1962090 (Counterclockwise)

Preceding gene: 119357538

Following gene: 119357533

Centisome position: 62.65

GC content: 48.12

Gene sequence:

>1305_bases
TTGAATATAACAACCTGTGAGAAGAACAGGGAAAAGGCCGTACTGATCGGTTTATGTTCCCCTCCCGAGTTACCCAGAAC
CCTTGTGGAAGAGTATCTTCAGGAGTTGGCGTTCCTTGCCGATACGGCAGGAGCGGATGTTCTCATGTCTATCATTCAGG
AAAAAAAACAGCGCGATCCGGCCTCTTTTCTCGGAAAAGGAAAGGTTGACGAACTTGCTGTTTTTGTGAAGGAAAATGCT
GTCGACATCGTTATCTGCGATGACGATCTTACTCCCGTGCAGGCAAGAAATCTCGAACGGGCTCTCGAGTGCAAGGTGAT
TGACCGTACAGGACTTATTTTGCAGATTTTTGCCATACGGGCACAATCATCCCAGGCGAAAATACAGGTAGAGCTTGCCC
AGCTTGAGTATATGCTGCCCCGGCTTTCCGGCCAGTGGACCCATTTATCCAAGCAGAAAGGAGGCATCGGAAGCAAAGGC
CCTGGTGAAACACAGATAGAAACTGACCGACGTCTTGTTCGAAACCGGATCTCCCTTCTCAAACGCAAGTTGCGTGAGGT
ATTGCTGCAACATGATACACAGACTCGCGGACGCCTGATTATTCCAAGGGTTGCCCTTGTAGGGTATACCAATGCAGGCA
AGTCAACGTTGATGAACATACTCTGCCCTGAAGCGGAGGCCTTTGCCGAAAATCGTCTTTTCGCAACGCTTGATACGAAA
ACCCGTCGGCTTGAACTTAAAATCAACAAGCTTGTTCTGCTCTCTGATACGGTTGGTTTTATCCGCAAGCTGCCGCACCA
TCTTGTAGAGAGCTTCAAGTCAACGCTCGACGAGGTGCTCCAGGCGGATTTTCTTCTCCATGTGATCGATGTCAGTCACC
CTGCTTTTGAGGAACAGATGGTGGTTGTCCGGGATACGCTCAGGGAACTTGGTGTTGAACATGACAACATCATTGATGTC
TTCAACAAGATCGATGCGCTTGAAGACCCGGGGGCTTTGGGAGCACTTCGCATGAAGTATCCCGAAGCCGTTTTTGTGTC
GGCAGCTCGGGGTTTGAACATCGCCGTGCTTAAAGAGATTATCAGCGATCATGTTGCTCTTGACTATAGGGAGCGGAAAA
TTCGTACACATGTGTCGAACTACAAGCTTATCGGTTATCTTTACGAACATACTGAAGTTGTCAGCAAACGGTATCTTGAT
GAAGATGTGGAGCTGACGTTCAGAGTGCATAAAAACAGCCTCAAACATATTGACGCGTTGATCAAGCCACTACTGATTCA
TGACTATGCCGTTGCAGATTTATAA

Upstream 100 bases:

>100_bases
ATAAGGTGTTGTCAAGATAAAACAATGCCTGTAATATAGCAAAATGCAGTGAGGTGTCTTGTTGCATTTATTATTATCAA
CGTAATCAAGACCATCCGTA

Downstream 100 bases:

>100_bases
CACGACCAGAAGAGAGCTTGCCGAATCGGTTTTGACTGAAGTGGTCACGACGGTTTTGCAGGAAGAGGGTTTTCTTATTG
AGTCTCTTGTTGCCGTCTAT

Product: GTP-binding protein, HSR1-related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MNITTCEKNREKAVLIGLCSPPELPRTLVEEYLQELAFLADTAGADVLMSIIQEKKQRDPASFLGKGKVDELAVFVKENA
VDIVICDDDLTPVQARNLERALECKVIDRTGLILQIFAIRAQSSQAKIQVELAQLEYMLPRLSGQWTHLSKQKGGIGSKG
PGETQIETDRRLVRNRISLLKRKLREVLLQHDTQTRGRLIIPRVALVGYTNAGKSTLMNILCPEAEAFAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHHLVESFKSTLDEVLQADFLLHVIDVSHPAFEEQMVVVRDTLRELGVEHDNIIDV
FNKIDALEDPGALGALRMKYPEAVFVSAARGLNIAVLKEIISDHVALDYRERKIRTHVSNYKLIGYLYEHTEVVSKRYLD
EDVELTFRVHKNSLKHIDALIKPLLIHDYAVADL

Sequences:

>Translated_434_residues
MNITTCEKNREKAVLIGLCSPPELPRTLVEEYLQELAFLADTAGADVLMSIIQEKKQRDPASFLGKGKVDELAVFVKENA
VDIVICDDDLTPVQARNLERALECKVIDRTGLILQIFAIRAQSSQAKIQVELAQLEYMLPRLSGQWTHLSKQKGGIGSKG
PGETQIETDRRLVRNRISLLKRKLREVLLQHDTQTRGRLIIPRVALVGYTNAGKSTLMNILCPEAEAFAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHHLVESFKSTLDEVLQADFLLHVIDVSHPAFEEQMVVVRDTLRELGVEHDNIIDV
FNKIDALEDPGALGALRMKYPEAVFVSAARGLNIAVLKEIISDHVALDYRERKIRTHVSNYKLIGYLYEHTEVVSKRYLD
EDVELTFRVHKNSLKHIDALIKPLLIHDYAVADL
>Mature_434_residues
MNITTCEKNREKAVLIGLCSPPELPRTLVEEYLQELAFLADTAGADVLMSIIQEKKQRDPASFLGKGKVDELAVFVKENA
VDIVICDDDLTPVQARNLERALECKVIDRTGLILQIFAIRAQSSQAKIQVELAQLEYMLPRLSGQWTHLSKQKGGIGSKG
PGETQIETDRRLVRNRISLLKRKLREVLLQHDTQTRGRLIIPRVALVGYTNAGKSTLMNILCPEAEAFAENRLFATLDTK
TRRLELKINKLVLLSDTVGFIRKLPHHLVESFKSTLDEVLQADFLLHVIDVSHPAFEEQMVVVRDTLRELGVEHDNIIDV
FNKIDALEDPGALGALRMKYPEAVFVSAARGLNIAVLKEIISDHVALDYRERKIRTHVSNYKLIGYLYEHTEVVSKRYLD
EDVELTFRVHKNSLKHIDALIKPLLIHDYAVADL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=270, Percent_Identity=35.1851851851852, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI310133116, Length=270, Percent_Identity=35.1851851851852, Blast_Score=122, Evalue=5e-28,
Organism=Homo sapiens, GI310124269, Length=262, Percent_Identity=35.1145038167939, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310124267, Length=262, Percent_Identity=35.1145038167939, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310124171, Length=262, Percent_Identity=35.1145038167939, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI310124169, Length=262, Percent_Identity=35.1145038167939, Blast_Score=119, Evalue=6e-27,
Organism=Escherichia coli, GI1790615, Length=382, Percent_Identity=42.9319371727749, Blast_Score=283, Evalue=2e-77,
Organism=Caenorhabditis elegans, GI17561038, Length=319, Percent_Identity=29.7805642633229, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24650079, Length=351, Percent_Identity=29.9145299145299, Blast_Score=121, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49090; Mature: 49090

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITTCEKNREKAVLIGLCSPPELPRTLVEEYLQELAFLADTAGADVLMSIIQEKKQRDP
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ASFLGKGKVDELAVFVKENAVDIVICDDDLTPVQARNLERALECKVIDRTGLILQIFAIR
HHHHCCCCHHHHEEEEECCCEEEEEECCCCCCHHHHHHHHHHHEEEECCCCCEEHHHHHH
AQSSQAKIQVELAQLEYMLPRLSGQWTHLSKQKGGIGSKGPGETQIETDRRLVRNRISLL
CCCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KRKLREVLLQHDTQTRGRLIIPRVALVGYTNAGKSTLMNILCPEAEAFAENRLFATLDTK
HHHHHHHHHHCCCCCCCEEEECEEEEEEECCCCHHHHHHHHCCCHHHHHCCCEEEEECCC
TRRLELKINKLVLLSDTVGFIRKLPHHLVESFKSTLDEVLQADFLLHVIDVSHPAFEEQM
CEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VVVRDTLRELGVEHDNIIDVFNKIDALEDPGALGALRMKYPEAVFVSAARGLNIAVLKEI
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCHHHHHHHH
ISDHVALDYRERKIRTHVSNYKLIGYLYEHTEVVSKRYLDEDVELTFRVHKNSLKHIDAL
HHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHH
IKPLLIHDYAVADL
HHHHHHHHHHHHCC
>Mature Secondary Structure
MNITTCEKNREKAVLIGLCSPPELPRTLVEEYLQELAFLADTAGADVLMSIIQEKKQRDP
CCCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
ASFLGKGKVDELAVFVKENAVDIVICDDDLTPVQARNLERALECKVIDRTGLILQIFAIR
HHHHCCCCHHHHEEEEECCCEEEEEECCCCCCHHHHHHHHHHHEEEECCCCCEEHHHHHH
AQSSQAKIQVELAQLEYMLPRLSGQWTHLSKQKGGIGSKGPGETQIETDRRLVRNRISLL
CCCCCCEEEEHHHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHH
KRKLREVLLQHDTQTRGRLIIPRVALVGYTNAGKSTLMNILCPEAEAFAENRLFATLDTK
HHHHHHHHHHCCCCCCCEEEECEEEEEEECCCCHHHHHHHHCCCHHHHHCCCEEEEECCC
TRRLELKINKLVLLSDTVGFIRKLPHHLVESFKSTLDEVLQADFLLHVIDVSHPAFEEQM
CEEEEEEEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHH
VVVRDTLRELGVEHDNIIDVFNKIDALEDPGALGALRMKYPEAVFVSAARGLNIAVLKEI
HHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHCCCHHHHHHHH
ISDHVALDYRERKIRTHVSNYKLIGYLYEHTEVVSKRYLDEDVELTFRVHKNSLKHIDAL
HHHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHH
IKPLLIHDYAVADL
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]