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The map label for this gene is purQ [H]

Identifier: 119357456

GI number: 119357456

Start: 1883977

End: 1884678

Strand: Reverse

Name: purQ [H]

Synonym: Cpha266_1655

Alternate gene names: 119357456

Gene position: 1884678-1883977 (Counterclockwise)

Preceding gene: 119357457

Following gene: 119357455

Centisome position: 60.14

GC content: 47.44

Gene sequence:

>702_bases
ATGGCGGATGTAAGGGTAGGGATTGTTGTTTTTCCCGGTTCAAATTGTGATCATGACACCGAGTATGCTGTAGCCTCTTT
CAGCGGCGTTGTACCGGTTATGCTCTGGCATAACGAACATGACCTTCATGAATCCGATGTCGTTATTCTGCCAGGCGGAT
TTTCCTATGGCGATTATCTGCGTGCCGGTTCGATTGCCCGGTTTTCTCCCATTATGCAGGAAGTGATTGCATTTGCCCGA
AAGGGGAGTCCTGTACTTGGCATTTGTAACGGTTTTCAGGTGTTGCTTGAAAGTGGCCTGCTTGAAGGAGCGCTTTCAAA
AAACCGGGATAAAAAATTTATCTGTGCCGAAACAACCATCAAAGCGGTAAACTGTTCTACCATGTTCACCAGTGCATACA
GGCATGGAGAGGTTCTTTCCATGCCTGTTGCCCATGGCGACGGGAACTATTTTGCTCCTCCTGAACTGCTTGAAAATCTT
CAGGAACATAATCAGATCGTTTTTACCTACGCTGATACGGATGGTAACGAAAGTCCTGAAGCCAATCCGAATGGTTCTGT
TTGTAATATTGCCGGATTAGTGAACCGGGAGGGGAATGTCCTTGGTCTTATGCCTCATCCGGAGCGAGCCAGCGAGAAGT
TACTTGGGTCAGAAGATGGCCGCAGGTTATTTGAATCCCTTTTTCAGCATGTTGTCGGGTAG

Upstream 100 bases:

>100_bases
ATCTGCTGTGAGATTTGTGAAAAGCTTCTTTCAAATCCGGTAATGGAAAACTACTTCTTTGAACTGGAATCTGAACCTGT
AAATTAAATATCACTCGACT

Downstream 100 bases:

>100_bases
AAAGCAAACCCGGACCATCAGAACGACCATAATTCCTTACGGATCGTGACGCAGAAATATAAAGTGTTTTCCTGGCTGCT
TTTTGATTTTGCCAACACTT

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 233; Mature: 232

Protein sequence:

>233_residues
MADVRVGIVVFPGSNCDHDTEYAVASFSGVVPVMLWHNEHDLHESDVVILPGGFSYGDYLRAGSIARFSPIMQEVIAFAR
KGSPVLGICNGFQVLLESGLLEGALSKNRDKKFICAETTIKAVNCSTMFTSAYRHGEVLSMPVAHGDGNYFAPPELLENL
QEHNQIVFTYADTDGNESPEANPNGSVCNIAGLVNREGNVLGLMPHPERASEKLLGSEDGRRLFESLFQHVVG

Sequences:

>Translated_233_residues
MADVRVGIVVFPGSNCDHDTEYAVASFSGVVPVMLWHNEHDLHESDVVILPGGFSYGDYLRAGSIARFSPIMQEVIAFAR
KGSPVLGICNGFQVLLESGLLEGALSKNRDKKFICAETTIKAVNCSTMFTSAYRHGEVLSMPVAHGDGNYFAPPELLENL
QEHNQIVFTYADTDGNESPEANPNGSVCNIAGLVNREGNVLGLMPHPERASEKLLGSEDGRRLFESLFQHVVG
>Mature_232_residues
ADVRVGIVVFPGSNCDHDTEYAVASFSGVVPVMLWHNEHDLHESDVVILPGGFSYGDYLRAGSIARFSPIMQEVIAFARK
GSPVLGICNGFQVLLESGLLEGALSKNRDKKFICAETTIKAVNCSTMFTSAYRHGEVLSMPVAHGDGNYFAPPELLENLQ
EHNQIVFTYADTDGNESPEANPNGSVCNIAGLVNREGNVLGLMPHPERASEKLLGSEDGRRLFESLFQHVVG

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994899, Length=183, Percent_Identity=27.3224043715847, Blast_Score=60, Evalue=1e-10,
Organism=Saccharomyces cerevisiae, GI6321498, Length=218, Percent_Identity=30.2752293577982, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24582111, Length=184, Percent_Identity=34.2391304347826, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24582109, Length=184, Percent_Identity=34.2391304347826, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17137292, Length=184, Percent_Identity=34.2391304347826, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 25296; Mature: 25165

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVRVGIVVFPGSNCDHDTEYAVASFSGVVPVMLWHNEHDLHESDVVILPGGFSYGDYL
CCCEEEEEEEECCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHH
RAGSIARFSPIMQEVIAFARKGSPVLGICNGFQVLLESGLLEGALSKNRDKKFICAETTI
HCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEE
KAVNCSTMFTSAYRHGEVLSMPVAHGDGNYFAPPELLENLQEHNQIVFTYADTDGNESPE
EEEEHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCC
ANPNGSVCNIAGLVNREGNVLGLMPHPERASEKLLGSEDGRRLFESLFQHVVG
CCCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ADVRVGIVVFPGSNCDHDTEYAVASFSGVVPVMLWHNEHDLHESDVVILPGGFSYGDYL
CCEEEEEEEECCCCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCEEEECCCCCCHHHH
RAGSIARFSPIMQEVIAFARKGSPVLGICNGFQVLLESGLLEGALSKNRDKKFICAETTI
HCCCCHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEECCEE
KAVNCSTMFTSAYRHGEVLSMPVAHGDGNYFAPPELLENLQEHNQIVFTYADTDGNESPE
EEEEHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEEECCCCCCCCC
ANPNGSVCNIAGLVNREGNVLGLMPHPERASEKLLGSEDGRRLFESLFQHVVG
CCCCCCEEEEEEEECCCCCEEEECCCCHHHHHHHCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA