Click here to switch to the map view.

The map label for this gene is yxiO [H]

Identifier: 119357455

GI number: 119357455

Start: 1882681

End: 1883931

Strand: Reverse

Name: yxiO [H]

Synonym: Cpha266_1654

Alternate gene names: 119357455

Gene position: 1883931-1882681 (Counterclockwise)

Preceding gene: 119357456

Following gene: 119357454

Centisome position: 60.11

GC content: 46.6

Gene sequence:

>1251_bases
GTGACGCAGAAATATAAAGTGTTTTCCTGGCTGCTTTTTGATTTTGCCAACACTTCCTTCAGCGTGATGATGGTGACGTT
TGCATTTCCTCTCTATTTCAAAAACGTCATCTGTTACGGGGAGACTTACGGAGATGCATGGTGGGGATTCAGCGTCAGCC
TTTCCATGCTGCTTGTTGCCGTTGTTTCTCCCGTCCTTGGAGCTGCTGCCGATTTTTCCGGCAGAAGAAAACGATTTCTC
TTTTCATTTACCCTTCTTTCCGTTATTGCGACGGCACTGCTCTCTTTTTCGGCTCCAGGCACGGTAGTTATCGCCGCCGG
TCTTTTTGTTGTTGCCAATATGGGTTTTGAAGGAGGGCTGGTTTTTTATGATGCATATCTTAAGGAACTCACCTCCGATA
AAAGCCTGGGAAGGCTCTCCGGTTATGGTTTTGCCATGGGCTATCTCGGCGCACTCTGTATTCTTCTTCTGCTCAGACCC
CTGCTTGCCGGAGGTATCGTTCCCGCCAATGCTCACAACGTCCAGTTGAGCTTTTTTCTTGTTGCGATTTTTTTTGCCGT
TTTTGCCTCACCGCTGTTTATTTCGTTGCGAGATGAAAAAAAACAGGGCGGGACAGCCATCTCCCTTGACGCTATAAGAC
GATCCGTCAGGGAAGTGCGCCATACGGTTCTTCATATCATGAGCTATCCGGATCTTGCAAGATTTCTTCTTGCTTACTTT
TTTTATAATGATGCTATTTTAACTGTTATAGCTTTTTCGTCGATCTATGCGCAGAATACGCTTGGATTCTCCACCAGCGA
GCTTATTATGTTTTTCATGCTTGTGCAGACGTCGGCTCTTCTCGGGTCTCTGTTTTTTGGCTTTATTACTGATAAGATCG
GCCCGAAGCGAACTATTGTCATAACGCTGCTTATCTGGTTCGTTGTGATTCTTTCAGCTATTATGTCAGAGCAGAAGGAG
CAGTTTTTTATGATAGGCATGCTGGCAGGTATAGCGATGGGCTCTTCACAGGCTGCATCACGATCAATGATGGCAAGGTT
GACTCCGCAAGAACATGTGACTGAGTTTTTCGGTTTTTATGATGGTACGTTTGGTAAGGCATCGGCGATTGCCGGTCCGT
TGCTCTTTGGTATGGTATCGTCAGGGTTTGGAAGCCAGAAGGCCGCCCTTGCTTCGCTTCTTGTCTTTTTTTCGCTTGGA
CTTTTTCTGATGACGAGGGTCAGGTCAGTAAGTACAGCCCCTCATCGTTGA

Upstream 100 bases:

>100_bases
GTCAGAAGATGGCCGCAGGTTATTTGAATCCCTTTTTCAGCATGTTGTCGGGTAGAAAGCAAACCCGGACCATCAGAACG
ACCATAATTCCTTACGGATC

Downstream 100 bases:

>100_bases
TGTTTGAAGGCATTGGAGGTGAGACGTTATGGCGCAAAGAGAAACAGCGCCCGGTCAAGGAACTCATCGATTTTCATATG
GATTGGTTGCATAAAAAAAA

Product: major facilitator transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MTQKYKVFSWLLFDFANTSFSVMMVTFAFPLYFKNVICYGETYGDAWWGFSVSLSMLLVAVVSPVLGAAADFSGRRKRFL
FSFTLLSVIATALLSFSAPGTVVIAAGLFVVANMGFEGGLVFYDAYLKELTSDKSLGRLSGYGFAMGYLGALCILLLLRP
LLAGGIVPANAHNVQLSFFLVAIFFAVFASPLFISLRDEKKQGGTAISLDAIRRSVREVRHTVLHIMSYPDLARFLLAYF
FYNDAILTVIAFSSIYAQNTLGFSTSELIMFFMLVQTSALLGSLFFGFITDKIGPKRTIVITLLIWFVVILSAIMSEQKE
QFFMIGMLAGIAMGSSQAASRSMMARLTPQEHVTEFFGFYDGTFGKASAIAGPLLFGMVSSGFGSQKAALASLLVFFSLG
LFLMTRVRSVSTAPHR

Sequences:

>Translated_416_residues
MTQKYKVFSWLLFDFANTSFSVMMVTFAFPLYFKNVICYGETYGDAWWGFSVSLSMLLVAVVSPVLGAAADFSGRRKRFL
FSFTLLSVIATALLSFSAPGTVVIAAGLFVVANMGFEGGLVFYDAYLKELTSDKSLGRLSGYGFAMGYLGALCILLLLRP
LLAGGIVPANAHNVQLSFFLVAIFFAVFASPLFISLRDEKKQGGTAISLDAIRRSVREVRHTVLHIMSYPDLARFLLAYF
FYNDAILTVIAFSSIYAQNTLGFSTSELIMFFMLVQTSALLGSLFFGFITDKIGPKRTIVITLLIWFVVILSAIMSEQKE
QFFMIGMLAGIAMGSSQAASRSMMARLTPQEHVTEFFGFYDGTFGKASAIAGPLLFGMVSSGFGSQKAALASLLVFFSLG
LFLMTRVRSVSTAPHR
>Mature_415_residues
TQKYKVFSWLLFDFANTSFSVMMVTFAFPLYFKNVICYGETYGDAWWGFSVSLSMLLVAVVSPVLGAAADFSGRRKRFLF
SFTLLSVIATALLSFSAPGTVVIAAGLFVVANMGFEGGLVFYDAYLKELTSDKSLGRLSGYGFAMGYLGALCILLLLRPL
LAGGIVPANAHNVQLSFFLVAIFFAVFASPLFISLRDEKKQGGTAISLDAIRRSVREVRHTVLHIMSYPDLARFLLAYFF
YNDAILTVIAFSSIYAQNTLGFSTSELIMFFMLVQTSALLGSLFFGFITDKIGPKRTIVITLLIWFVVILSAIMSEQKEQ
FFMIGMLAGIAMGSSQAASRSMMARLTPQEHVTEFFGFYDGTFGKASAIAGPLLFGMVSSGFGSQKAALASLLVFFSLGL
FLMTRVRSVSTAPHR

Specific function: Unknown

COG id: COG2270

COG function: function code R; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 45559; Mature: 45428

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQKYKVFSWLLFDFANTSFSVMMVTFAFPLYFKNVICYGETYGDAWWGFSVSLSMLLVA
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
VVSPVLGAAADFSGRRKRFLFSFTLLSVIATALLSFSAPGTVVIAAGLFVVANMGFEGGL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
VFYDAYLKELTSDKSLGRLSGYGFAMGYLGALCILLLLRPLLAGGIVPANAHNVQLSFFL
HHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
VAIFFAVFASPLFISLRDEKKQGGTAISLDAIRRSVREVRHTVLHIMSYPDLARFLLAYF
HHHHHHHHHCCEEEEEECHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FYNDAILTVIAFSSIYAQNTLGFSTSELIMFFMLVQTSALLGSLFFGFITDKIGPKRTIV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ITLLIWFVVILSAIMSEQKEQFFMIGMLAGIAMGSSQAASRSMMARLTPQEHVTEFFGFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
DGTFGKASAIAGPLLFGMVSSGFGSQKAALASLLVFFSLGLFLMTRVRSVSTAPHR
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TQKYKVFSWLLFDFANTSFSVMMVTFAFPLYFKNVICYGETYGDAWWGFSVSLSMLLVA
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHH
VVSPVLGAAADFSGRRKRFLFSFTLLSVIATALLSFSAPGTVVIAAGLFVVANMGFEGGL
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCH
VFYDAYLKELTSDKSLGRLSGYGFAMGYLGALCILLLLRPLLAGGIVPANAHNVQLSFFL
HHHHHHHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
VAIFFAVFASPLFISLRDEKKQGGTAISLDAIRRSVREVRHTVLHIMSYPDLARFLLAYF
HHHHHHHHHCCEEEEEECHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
FYNDAILTVIAFSSIYAQNTLGFSTSELIMFFMLVQTSALLGSLFFGFITDKIGPKRTIV
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
ITLLIWFVVILSAIMSEQKEQFFMIGMLAGIAMGSSQAASRSMMARLTPQEHVTEFFGFY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
DGTFGKASAIAGPLLFGMVSSGFGSQKAALASLLVFFSLGLFLMTRVRSVSTAPHR
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]