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The map label for this gene is sucC [H]

Identifier: 119357118

GI number: 119357118

Start: 1498985

End: 1500181

Strand: Reverse

Name: sucC [H]

Synonym: Cpha266_1307

Alternate gene names: 119357118

Gene position: 1500181-1498985 (Counterclockwise)

Preceding gene: 119357120

Following gene: 119357117

Centisome position: 47.87

GC content: 50.38

Gene sequence:

>1197_bases
ATGGCTAAGATACTTGAAGGGCCTGCCATGAAGCTTTTCAACAAGTGGGGCATTCCGGTGCCGAACTATGTTGTAATCAT
GGACCCTGAACGCCTTGCGCAGCTCGGGGAAGCTAATAAATGGCTGCGAGAATCAAAACTTGTTGTTAAAGCCCACGAGG
CTATTGGCGGCAGATTCAAGCTCGGTCTCGTTAAGCTCGGACTGAATCTTGAGGAGGCGCTTGAGGCTTCCCGCGAGATG
ATTGGCCGAAAGATCGGTACGGCTGTTGTGCGTCAGGTTATTGTTGCAGAAATGCTTGAGCATGATGAAGAGTACTATGT
TTCGATTGCCGGAAACCGCGACGGCGCGGAACTTCTGCTTTCGACAAAGGGCGGCGTTGATATCGAAGATAACTGGGATA
CCGTCAAGCGTCTCTTTATTCCCATGGATGAAACACCGAGTGTCGAACGTCTTACAGAGGTTGCCGCTGAGGCCGGTTTT
ACTGGCGAAGTTGCCGAACGAGTCGCAAAAATCGCTGCGCGCCTGATTCTCTGTTTTGATAATGAAGATGCGCAATCCAT
CGAAATCAATCCTCTCGTTATTCGCAAAAGCGACATGCGTTTTGCCGCTCTTGATGCGGTGATGAATGTTGACTACGATG
CCCGGTTCCGTCATGCTGACTGGGATTTCAAACCGGTCTCCGAAATAGGGCGCCCCTATACCGAGGCTGAACAGCAGATC
ATGGAGATCGATGCAAGAATAAAGGGATCAGTCAAGTTTGTTGAAGTTCCCGGTGGCGAAATCGCCCTCCTGACCGCTGG
CGGCGGTGCTTCAGTATTCTACTCCGACGCTGTTGTTGCAAGAGGAGGAACTATTGCCAATTATGCCGAATATTCAGGTG
ATCCTCCGGATTGGGCAGTTGAGGCGCTTACGGAAACGATTTGTCGTTTACCGAAAATCCGTCATATCATCGTTGGTGGT
GCCATAGCAAATTTCACGGACGTTAAGGCTACCTTCAGCGGTATTATAAACGGTCTGCGCGAAAGCCGCTCGAAAGGCTA
CCTTCAAAATGTCACAATCTGGGTACGTCGAGGCGGGCCGAATGAAAATCAGGGTCTTGCGGCTATCCGGAAACTGCAGG
ATGAGGGTTTTGATATCCATGTGTATGACCGCAGTATGCCAATGACCGACATTGTCGATCTTGCCATGAACTCATAG

Upstream 100 bases:

>100_bases
GTTGGATAAAAAACAAATATAGTTATCTTAAAACTTTGCGCATTTCTATTGTTGTTTCATTCCGGTTTTCATTCCAGTTA
ACATACAAATAATAAAGAGT

Downstream 100 bases:

>100_bases
ACATACCAACGGAAAGCATCATCTATCAAAAGAACCTATAACTTTTTAACCGGAAAGAAACGTGAGTATTTTAGCAAATA
AAGACACGCGAGCGGTTATC

Product: ATP citrate lyase subunit 1

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MAKILEGPAMKLFNKWGIPVPNYVVIMDPERLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKLGLNLEEALEASREM
IGRKIGTAVVRQVIVAEMLEHDEEYYVSIAGNRDGAELLLSTKGGVDIEDNWDTVKRLFIPMDETPSVERLTEVAAEAGF
TGEVAERVAKIAARLILCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPYTEAEQQI
MEIDARIKGSVKFVEVPGGEIALLTAGGGASVFYSDAVVARGGTIANYAEYSGDPPDWAVEALTETICRLPKIRHIIVGG
AIANFTDVKATFSGIINGLRESRSKGYLQNVTIWVRRGGPNENQGLAAIRKLQDEGFDIHVYDRSMPMTDIVDLAMNS

Sequences:

>Translated_398_residues
MAKILEGPAMKLFNKWGIPVPNYVVIMDPERLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKLGLNLEEALEASREM
IGRKIGTAVVRQVIVAEMLEHDEEYYVSIAGNRDGAELLLSTKGGVDIEDNWDTVKRLFIPMDETPSVERLTEVAAEAGF
TGEVAERVAKIAARLILCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPYTEAEQQI
MEIDARIKGSVKFVEVPGGEIALLTAGGGASVFYSDAVVARGGTIANYAEYSGDPPDWAVEALTETICRLPKIRHIIVGG
AIANFTDVKATFSGIINGLRESRSKGYLQNVTIWVRRGGPNENQGLAAIRKLQDEGFDIHVYDRSMPMTDIVDLAMNS
>Mature_397_residues
AKILEGPAMKLFNKWGIPVPNYVVIMDPERLAQLGEANKWLRESKLVVKAHEAIGGRFKLGLVKLGLNLEEALEASREMI
GRKIGTAVVRQVIVAEMLEHDEEYYVSIAGNRDGAELLLSTKGGVDIEDNWDTVKRLFIPMDETPSVERLTEVAAEAGFT
GEVAERVAKIAARLILCFDNEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPYTEAEQQIM
EIDARIKGSVKFVEVPGGEIALLTAGGGASVFYSDAVVARGGTIANYAEYSGDPPDWAVEALTETICRLPKIRHIIVGGA
IANFTDVKATFSGIINGLRESRSKGYLQNVTIWVRRGGPNENQGLAAIRKLQDEGFDIHVYDRSMPMTDIVDLAMNS

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI38569423, Length=386, Percent_Identity=33.160621761658, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI38569421, Length=386, Percent_Identity=33.160621761658, Blast_Score=172, Evalue=4e-43,
Organism=Homo sapiens, GI11321583, Length=330, Percent_Identity=28.4848484848485, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI157779135, Length=381, Percent_Identity=27.2965879265092, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI294862256, Length=328, Percent_Identity=27.7439024390244, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI1786948, Length=324, Percent_Identity=26.5432098765432, Blast_Score=69, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17551266, Length=426, Percent_Identity=31.4553990610329, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17557344, Length=426, Percent_Identity=30.5164319248826, Blast_Score=142, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17539378, Length=382, Percent_Identity=28.2722513089005, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17567829, Length=418, Percent_Identity=26.7942583732057, Blast_Score=78, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6321683, Length=421, Percent_Identity=25.8907363420428, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281363475, Length=387, Percent_Identity=33.8501291989664, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281363473, Length=387, Percent_Identity=33.8501291989664, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281363477, Length=387, Percent_Identity=33.8501291989664, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI21356231, Length=400, Percent_Identity=28.5, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281361397, Length=340, Percent_Identity=27.6470588235294, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281361395, Length=340, Percent_Identity=27.6470588235294, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI161078106, Length=340, Percent_Identity=27.6470588235294, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24645208, Length=340, Percent_Identity=27.6470588235294, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 43897; Mature: 43766

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKILEGPAMKLFNKWGIPVPNYVVIMDPERLAQLGEANKWLRESKLVVKAHEAIGGRFK
CCCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEE
LGLVKLGLNLEEALEASREMIGRKIGTAVVRQVIVAEMLEHDEEYYVSIAGNRDGAELLL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
STKGGVDIEDNWDTVKRLFIPMDETPSVERLTEVAAEAGFTGEVAERVAKIAARLILCFD
ECCCCCCCCCCHHHHHHEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEC
NEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPYTEAEQQI
CCCCCEEECCEEEEEECCCHHHHHHHHHCCCCCCCEECCCCCCCCHHHHCCCHHHHHHHH
MEIDARIKGSVKFVEVPGGEIALLTAGGGASVFYSDAVVARGGTIANYAEYSGDPPDWAV
HHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEECCEEEECCCCEECHHHCCCCCCHHHH
EALTETICRLPKIRHIIVGGAIANFTDVKATFSGIINGLRESRSKGYLQNVTIWVRRGGP
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
NENQGLAAIRKLQDEGFDIHVYDRSMPMTDIVDLAMNS
CCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCC
>Mature Secondary Structure 
AKILEGPAMKLFNKWGIPVPNYVVIMDPERLAQLGEANKWLRESKLVVKAHEAIGGRFK
CCCCCCHHHHHHHHCCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHEEEHHHCCCEEE
LGLVKLGLNLEEALEASREMIGRKIGTAVVRQVIVAEMLEHDEEYYVSIAGNRDGAELLL
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEE
STKGGVDIEDNWDTVKRLFIPMDETPSVERLTEVAAEAGFTGEVAERVAKIAARLILCFD
ECCCCCCCCCCHHHHHHEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHEEEEEC
NEDAQSIEINPLVIRKSDMRFAALDAVMNVDYDARFRHADWDFKPVSEIGRPYTEAEQQI
CCCCCEEECCEEEEEECCCHHHHHHHHHCCCCCCCEECCCCCCCCHHHHCCCHHHHHHHH
MEIDARIKGSVKFVEVPGGEIALLTAGGGASVFYSDAVVARGGTIANYAEYSGDPPDWAV
HHHHHHCCCCEEEEECCCCCEEEEEECCCCEEEECCEEEECCCCEECHHHCCCCCCHHHH
EALTETICRLPKIRHIIVGGAIANFTDVKATFSGIINGLRESRSKGYLQNVTIWVRRGGP
HHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEECCC
NENQGLAAIRKLQDEGFDIHVYDRSMPMTDIVDLAMNS
CCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA