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The map label for this gene is sucD1 [H]

Identifier: 119357117

GI number: 119357117

Start: 1497091

End: 1498923

Strand: Reverse

Name: sucD1 [H]

Synonym: Cpha266_1306

Alternate gene names: 119357117

Gene position: 1498923-1497091 (Counterclockwise)

Preceding gene: 119357118

Following gene: 119357116

Centisome position: 47.83

GC content: 50.63

Gene sequence:

>1833_bases
GTGAGTATTTTAGCAAATAAAGACACGCGAGCGGTTATCATCGGCGGTATAGCCGGATTGAACGCCGCAAGGAGGATGGC
CCAGTTTGACTTTCTCGTGAACAGACCACTGACTGTTCAGGCATTTGTCTATCCTCCCGAAGAAGGTCAGCAAAAAGAGA
TTTACCGCGGTGGCGAACTGAAAAATATTGCGGTATACTCATCGCTTGAAAAAGCACTTGAGGAGCATCCCGAGATCAAT
ACTGCGCTGATCTATATCGGCGCATCAAGGGCTTTCCAGTCGGCAAAGGAAGCTCTTGAGTCAAAAGGCATCAAGCTTGT
TTCCATGATTACCGAAGGGGTGCCTGAAAAAGATGCCAAGAGATTGCGCAAACTTGCCGCGGAAAACAACAAACTGTTTA
ACGGCCCCTCTTCAATCGGCATCATGTCGGCAGGCGAGTGCAGGCTCGGCGTTATCGGAGGTGAATTCAAAAACCTCAAA
CTCTGCAATCTCTATCGTCCGGGTTCATTCGGCGTTATCACCAAATCCGGCGGTCTTTCAAACGAAGCCATGTGGTTGTG
CGCCCAGAACGGTAACGGTATTACCACGGCCGTTGCCATTGGCGGCGACTCATTCCCGGGCACAGACTTCGTTACCTATC
TTGAAATGTTTGAAAACGACCCCGATACCAAGGCTGTGGTTATCGTCGGGGAGGTTGGAGGAACTCTCGAAGAGGAAGCT
GCCGACTGGCTCGCTGCAGAAAAACGCCGCATAAGGCTCATTGCCGCAATCGGCGGAACCTGCCAGGAAGTACTTCCGCA
GGGAATGAAGTTCGGACATGCCGGTGCCAAGGAGGGGAAAAAAGGTCTTGGTTCAGCACGCTCGAAAATGAATGCTCTGC
GTGACGCAGGCGCGCTTGTTCCCGATACTTTCGGAGGCCTCAGCAAAGCTATCAAGCAGGTTTACGAAGAACTGCTTGCC
GATGGCGCCATCAAACCTGAACCGGATATCGATGAAGCGCTTCTTCCGGAACTTCCGCTGAAGGTTCAGGAAATCATGAA
GCAGGGCGAAGTAATTGTAGAACCCCTGATTCGCACCACCATTTCCGACGACCGTGGCGAAGAGCCTCGCTATGTTGGCT
ATGCCGCATCCGAGCTTTGTGAGAAAGGGTACGGTATCGAAGATGTCATCGGCCTTTTGTGGAATAAAAAACTTCCGTCA
AGGCAGGAGTCTGAAATACTCAAACGCATTATCATGATCTCGGCCGATCACGGCCCAGCGGTTTCAGGCGCATTCGGTTC
AATTATAGCTGCCTGTGCCGGTATCGACATGCCTCAGGCGGTTTCGGCAGGTATGACCATGATCGGGCCACGGTTCGGCG
GGGCAGTAACCAATGCCGGTAAATATTTCAAGCACGGCGTCAAGGATTTCCCCAATGATATTCCGGGATTTCTCTCATGG
ATGAAACTTAACGTCGGACCGGTTCCGGGTATCGGACATCGAGTCAAAAGCGTGAAGAATCCTGACAAGCGGGTGAAGTA
TCTTGTTGATTATGTCAAAAACAGTACATCTCTTCATACGCCATGTCTTGACTACGCGCTTGAAGTAGAAAAAATCACAA
CCGCAAAGAAAGACAATCTCATTCTGAACGTTGATGGAACGATCGGCTGTATTCTGGTGGATCTCGAGTTCCCGGAATAC
TCGCTCAACGGCTTCTTTGTGCTTGCCCGCACAATCGGCATGATCGGACACTGGATCGATCAGAACAATCAGTCCGCACG
ACTGATCAGACTGTACGATTATCTGATCAACTATGCCGTCAAGGAAGAACGAGAGGTTCCTGAAAGGAAGTAA

Upstream 100 bases:

>100_bases
CCAATGACCGACATTGTCGATCTTGCCATGAACTCATAGACATACCAACGGAAAGCATCATCTATCAAAAGAACCTATAA
CTTTTTAACCGGAAAGAAAC

Downstream 100 bases:

>100_bases
GTTTTCTCAAAACAGGATAACAGCAACGGCTCTTTGGAGTATGCGCTGAAAAAAGAGCAGGTATGGCAACATACCTGCTC
TTTTTTTTTGATCGAAAAAG

Product: ATP citrate lyase subunit 2

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha 1; SCS-alpha 1 [H]

Number of amino acids: Translated: 610; Mature: 609

Protein sequence:

>610_residues
MSILANKDTRAVIIGGIAGLNAARRMAQFDFLVNRPLTVQAFVYPPEEGQQKEIYRGGELKNIAVYSSLEKALEEHPEIN
TALIYIGASRAFQSAKEALESKGIKLVSMITEGVPEKDAKRLRKLAAENNKLFNGPSSIGIMSAGECRLGVIGGEFKNLK
LCNLYRPGSFGVITKSGGLSNEAMWLCAQNGNGITTAVAIGGDSFPGTDFVTYLEMFENDPDTKAVVIVGEVGGTLEEEA
ADWLAAEKRRIRLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGLGSARSKMNALRDAGALVPDTFGGLSKAIKQVYEELLA
DGAIKPEPDIDEALLPELPLKVQEIMKQGEVIVEPLIRTTISDDRGEEPRYVGYAASELCEKGYGIEDVIGLLWNKKLPS
RQESEILKRIIMISADHGPAVSGAFGSIIAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKHGVKDFPNDIPGFLSW
MKLNVGPVPGIGHRVKSVKNPDKRVKYLVDYVKNSTSLHTPCLDYALEVEKITTAKKDNLILNVDGTIGCILVDLEFPEY
SLNGFFVLARTIGMIGHWIDQNNQSARLIRLYDYLINYAVKEEREVPERK

Sequences:

>Translated_610_residues
MSILANKDTRAVIIGGIAGLNAARRMAQFDFLVNRPLTVQAFVYPPEEGQQKEIYRGGELKNIAVYSSLEKALEEHPEIN
TALIYIGASRAFQSAKEALESKGIKLVSMITEGVPEKDAKRLRKLAAENNKLFNGPSSIGIMSAGECRLGVIGGEFKNLK
LCNLYRPGSFGVITKSGGLSNEAMWLCAQNGNGITTAVAIGGDSFPGTDFVTYLEMFENDPDTKAVVIVGEVGGTLEEEA
ADWLAAEKRRIRLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGLGSARSKMNALRDAGALVPDTFGGLSKAIKQVYEELLA
DGAIKPEPDIDEALLPELPLKVQEIMKQGEVIVEPLIRTTISDDRGEEPRYVGYAASELCEKGYGIEDVIGLLWNKKLPS
RQESEILKRIIMISADHGPAVSGAFGSIIAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKHGVKDFPNDIPGFLSW
MKLNVGPVPGIGHRVKSVKNPDKRVKYLVDYVKNSTSLHTPCLDYALEVEKITTAKKDNLILNVDGTIGCILVDLEFPEY
SLNGFFVLARTIGMIGHWIDQNNQSARLIRLYDYLINYAVKEEREVPERK
>Mature_609_residues
SILANKDTRAVIIGGIAGLNAARRMAQFDFLVNRPLTVQAFVYPPEEGQQKEIYRGGELKNIAVYSSLEKALEEHPEINT
ALIYIGASRAFQSAKEALESKGIKLVSMITEGVPEKDAKRLRKLAAENNKLFNGPSSIGIMSAGECRLGVIGGEFKNLKL
CNLYRPGSFGVITKSGGLSNEAMWLCAQNGNGITTAVAIGGDSFPGTDFVTYLEMFENDPDTKAVVIVGEVGGTLEEEAA
DWLAAEKRRIRLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGLGSARSKMNALRDAGALVPDTFGGLSKAIKQVYEELLAD
GAIKPEPDIDEALLPELPLKVQEIMKQGEVIVEPLIRTTISDDRGEEPRYVGYAASELCEKGYGIEDVIGLLWNKKLPSR
QESEILKRIIMISADHGPAVSGAFGSIIAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKHGVKDFPNDIPGFLSWM
KLNVGPVPGIGHRVKSVKNPDKRVKYLVDYVKNSTSLHTPCLDYALEVEKITTAKKDNLILNVDGTIGCILVDLEFPEYS
LNGFFVLARTIGMIGHWIDQNNQSARLIRLYDYLINYAVKEEREVPERK

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI38569421, Length=619, Percent_Identity=35.702746365105, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI38569423, Length=619, Percent_Identity=35.702746365105, Blast_Score=368, Evalue=1e-102,
Organism=Homo sapiens, GI109452591, Length=219, Percent_Identity=33.7899543378995, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1786949, Length=317, Percent_Identity=32.4921135646688, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17557344, Length=606, Percent_Identity=38.4488448844884, Blast_Score=387, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17551266, Length=604, Percent_Identity=37.9139072847682, Blast_Score=383, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17550194, Length=243, Percent_Identity=36.2139917695473, Blast_Score=128, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17553126, Length=321, Percent_Identity=29.2834890965732, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324716, Length=253, Percent_Identity=30.8300395256917, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI281363477, Length=610, Percent_Identity=35.7377049180328, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI281363475, Length=610, Percent_Identity=35.7377049180328, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI281363473, Length=610, Percent_Identity=35.7377049180328, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI21356559, Length=235, Percent_Identity=32.7659574468085, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI28574296, Length=196, Percent_Identity=36.2244897959184, Blast_Score=106, Evalue=4e-23,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 66226; Mature: 66095

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILANKDTRAVIIGGIAGLNAARRMAQFDFLVNRPLTVQAFVYPPEEGQQKEIYRGGEL
CCCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHCCCCC
KNIAVYSSLEKALEEHPEINTALIYIGASRAFQSAKEALESKGIKLVSMITEGVPEKDAK
CHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEHHHHCCCCCHHHH
RLRKLAAENNKLFNGPSSIGIMSAGECRLGVIGGEFKNLKLCNLYRPGSFGVITKSGGLS
HHHHHHHCCCCEECCCCCCCEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEECCCCCC
NEAMWLCAQNGNGITTAVAIGGDSFPGTDFVTYLEMFENDPDTKAVVIVGEVGGTLEEEA
CCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
ADWLAAEKRRIRLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGLGSARSKMNALRDAGALV
HHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PDTFGGLSKAIKQVYEELLADGAIKPEPDIDEALLPELPLKVQEIMKQGEVIVEPLIRTT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
ISDDRGEEPRYVGYAASELCEKGYGIEDVIGLLWNKKLPSRQESEILKRIIMISADHGPA
CCCCCCCCCCEECHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCC
VSGAFGSIIAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKHGVKDFPNDIPGFLSW
CCCHHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCHHHCHHHHHHHHHHCCCCHHHHHHH
MKLNVGPVPGIGHRVKSVKNPDKRVKYLVDYVKNSTSLHTPCLDYALEVEKITTAKKDNL
HHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCE
ILNVDGTIGCILVDLEFPEYSLNGFFVLARTIGMIGHWIDQNNQSARLIRLYDYLINYAV
EEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KEEREVPERK
HHHHCCCCCC
>Mature Secondary Structure 
SILANKDTRAVIIGGIAGLNAARRMAQFDFLVNRPLTVQAFVYPPEEGQQKEIYRGGEL
CCCCCCCCCEEEEECHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHCCCCC
KNIAVYSSLEKALEEHPEINTALIYIGASRAFQSAKEALESKGIKLVSMITEGVPEKDAK
CHHHHHHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHCCCEEEHHHHCCCCCHHHH
RLRKLAAENNKLFNGPSSIGIMSAGECRLGVIGGEFKNLKLCNLYRPGSFGVITKSGGLS
HHHHHHHCCCCEECCCCCCCEEECCCEEEEEECCCCCCEEEEEEECCCCCEEEECCCCCC
NEAMWLCAQNGNGITTAVAIGGDSFPGTDFVTYLEMFENDPDTKAVVIVGEVGGTLEEEA
CCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHH
ADWLAAEKRRIRLIAAIGGTCQEVLPQGMKFGHAGAKEGKKGLGSARSKMNALRDAGALV
HHHHHHHHHHEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCC
PDTFGGLSKAIKQVYEELLADGAIKPEPDIDEALLPELPLKVQEIMKQGEVIVEPLIRTT
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHCCCCCHHHHHHHHCCHHHHHHHHHHH
ISDDRGEEPRYVGYAASELCEKGYGIEDVIGLLWNKKLPSRQESEILKRIIMISADHGPA
CCCCCCCCCCEECHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHEECCCCCC
VSGAFGSIIAACAGIDMPQAVSAGMTMIGPRFGGAVTNAGKYFKHGVKDFPNDIPGFLSW
CCCHHHHHHHHHHCCCCHHHHHCCCHHCCCCCCCCHHHCHHHHHHHHHHCCCCHHHHHHH
MKLNVGPVPGIGHRVKSVKNPDKRVKYLVDYVKNSTSLHTPCLDYALEVEKITTAKKDNL
HHHCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCE
ILNVDGTIGCILVDLEFPEYSLNGFFVLARTIGMIGHWIDQNNQSARLIRLYDYLINYAV
EEEECCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
KEEREVPERK
HHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]