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The map label for this gene is ald [H]

Identifier: 119356703

GI number: 119356703

Start: 996912

End: 998132

Strand: Reverse

Name: ald [H]

Synonym: Cpha266_0875

Alternate gene names: 119356703

Gene position: 998132-996912 (Counterclockwise)

Preceding gene: 119356704

Following gene: 119356700

Centisome position: 31.85

GC content: 48.81

Gene sequence:

>1221_bases
ATGGGATACAGTGGTGATACAGAAAGTATTGAGTTTGAGCTTGGAGTAAAAACCCTTGAGCGCTGGCTGATCAAGCCTGG
AAAAACGATGAACATCGTTCTCGGTATTCCAAAAGAACGCGCTCAGGACGAACGACGGGTCGCCATCTCTCCTGCCGGCG
TGCAGATTCTGACCGAACATGGAATCAGGGTGGTTATTGAACAGTCGGCCGGACATTTCTGTAATTTTTCCGATATCGAT
TATTCTGAAGCAGGTGCGGTTATTGTTGCTTCACCTGAAGAACTTTTTGCCGATTCCAACGTCATTGTCAAGGTTTCTCC
GCCTCAGCCGGAAGAACTGCCCCTGTTCACTCCCGGCCAGATGCTGATTTCAGCGCTGCATCTTGGAACAGTAAGCCGCC
ACGTCATCGAAACGCTGCTGGAAAAAAACATCACCGCTCTTGGTTTTGAATTTATCGAGACCAAAGATGGCGAACTGCCG
ATTGTCAGAACGCTGAGTGAAATAGCAGGCTCTCTTGCTATTCAAACCGCTGCAAAATATCTTGAAACCGGCTATGGAGG
CAGCGGAATTCTTCTTGGCGGCATTGCCGGGGTGCCTCCTGCACACGTCACAATCGTAGGCGCCGGCACAGTAGGCCTTT
TTGCGGCTCAGGATGCGCTCGGACTTGGAGCCCAGGTAACAGTTATCGACAAGGAGATCAACCGACTGAGAAGATTTGAA
GCTTTTTTCAACCGGCATCTGGTCACCGCAATAGCCAATGATCACTACATAGCCGAAATTGCCCGATTTTCGGATGTCAT
GATCGGTGCGTTGAGCCCGAAACAAAAAATAATAAAACCGCTCGTAAGCGAACAGGTCGTCAAATCCATGAAACCGGGTT
CCGTCATTATTGACGTTTCTATCGACCAGGGCGCATGTTTCTCAACAAGCCGGCACACCTCCCACACCAATCCTATTTAT
GTCAAGCACGGAGTAACACATTATTGCGTCCCTAACATACCCTCAGCCGTTGCAAAAACCGCTTCATTTGCTCTCACCAA
CACCCTGCTGCCGTTTCTCCTGAAACTATCGGAGCATGAAACCATTTCCGATATTCTCTGGAAAAGCCACAGCCTGAGAA
AAGGCACCTATATATTCAAGGGATATGTAACCCGGAAAATTCTTGCGGAGCTTCTCGATTTTCCTTTCCGCGAAATTGAC
ATGTTGCTTGCTGCGAGTTGA

Upstream 100 bases:

>100_bases
TAAAAATTACAGCAAAATAAGTGCAACTGCCCCCTGACGTGAAGGTTCCTCCCACCTTTCCTTGCGACAGAAGGCGAAAC
CATTTTACCCGATTTGCTTG

Downstream 100 bases:

>100_bases
GTTCCCGTTCAGGGTATGGCATCAGAGATATGCAAGCGGCTTACCCATCTGTCGGGCAATATAGGAGGCACATGAAACGC
CTGAATAGGTCACAGCAATA

Product: L-alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MGYSGDTESIEFELGVKTLERWLIKPGKTMNIVLGIPKERAQDERRVAISPAGVQILTEHGIRVVIEQSAGHFCNFSDID
YSEAGAVIVASPEELFADSNVIVKVSPPQPEELPLFTPGQMLISALHLGTVSRHVIETLLEKNITALGFEFIETKDGELP
IVRTLSEIAGSLAIQTAAKYLETGYGGSGILLGGIAGVPPAHVTIVGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFE
AFFNRHLVTAIANDHYIAEIARFSDVMIGALSPKQKIIKPLVSEQVVKSMKPGSVIIDVSIDQGACFSTSRHTSHTNPIY
VKHGVTHYCVPNIPSAVAKTASFALTNTLLPFLLKLSEHETISDILWKSHSLRKGTYIFKGYVTRKILAELLDFPFREID
MLLAAS

Sequences:

>Translated_406_residues
MGYSGDTESIEFELGVKTLERWLIKPGKTMNIVLGIPKERAQDERRVAISPAGVQILTEHGIRVVIEQSAGHFCNFSDID
YSEAGAVIVASPEELFADSNVIVKVSPPQPEELPLFTPGQMLISALHLGTVSRHVIETLLEKNITALGFEFIETKDGELP
IVRTLSEIAGSLAIQTAAKYLETGYGGSGILLGGIAGVPPAHVTIVGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFE
AFFNRHLVTAIANDHYIAEIARFSDVMIGALSPKQKIIKPLVSEQVVKSMKPGSVIIDVSIDQGACFSTSRHTSHTNPIY
VKHGVTHYCVPNIPSAVAKTASFALTNTLLPFLLKLSEHETISDILWKSHSLRKGTYIFKGYVTRKILAELLDFPFREID
MLLAAS
>Mature_405_residues
GYSGDTESIEFELGVKTLERWLIKPGKTMNIVLGIPKERAQDERRVAISPAGVQILTEHGIRVVIEQSAGHFCNFSDIDY
SEAGAVIVASPEELFADSNVIVKVSPPQPEELPLFTPGQMLISALHLGTVSRHVIETLLEKNITALGFEFIETKDGELPI
VRTLSEIAGSLAIQTAAKYLETGYGGSGILLGGIAGVPPAHVTIVGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFEA
FFNRHLVTAIANDHYIAEIARFSDVMIGALSPKQKIIKPLVSEQVVKSMKPGSVIIDVSIDQGACFSTSRHTSHTNPIYV
KHGVTHYCVPNIPSAVAKTASFALTNTLLPFLLKLSEHETISDILWKSHSLRKGTYIFKGYVTRKILAELLDFPFREIDM
LLAAS

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=371, Percent_Identity=29.3800539083558, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI122939153, Length=371, Percent_Identity=29.3800539083558, Blast_Score=121, Evalue=1e-27,
Organism=Escherichia coli, GI1787887, Length=355, Percent_Identity=28.7323943661972, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17550456, Length=350, Percent_Identity=29.7142857142857, Blast_Score=140, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 44080; Mature: 43948

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGYSGDTESIEFELGVKTLERWLIKPGKTMNIVLGIPKERAQDERRVAISPAGVQILTEH
CCCCCCCCCEEEEECHHHHHHHHCCCCCEEEEEEECCHHHCCCCCEEEECCCCEEEEECC
GIRVVIEQSAGHFCNFSDIDYSEAGAVIVASPEELFADSNVIVKVSPPQPEELPLFTPGQ
CEEEEEECCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCEEEEECCCCCCCCCCCCCHH
MLISALHLGTVSRHVIETLLEKNITALGFEFIETKDGELPIVRTLSEIAGSLAIQTAAKY
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LETGYGGSGILLGGIAGVPPAHVTIVGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFE
HHCCCCCCCEEECCCCCCCCCEEEEEECCCHHHEEHHHHHCCCCEEEEEHHHHHHHHHHH
AFFNRHLVTAIANDHYIAEIARFSDVMIGALSPKQKIIKPLVSEQVVKSMKPGSVIIDVS
HHHCCCEEEEECCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
IDQGACFSTSRHTSHTNPIYVKHGVTHYCVPNIPSAVAKTASFALTNTLLPFLLKLSEHE
ECCCCCCCCCCCCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
TISDILWKSHSLRKGTYIFKGYVTRKILAELLDFPFREIDMLLAAS
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHCCC
>Mature Secondary Structure 
GYSGDTESIEFELGVKTLERWLIKPGKTMNIVLGIPKERAQDERRVAISPAGVQILTEH
CCCCCCCCEEEEECHHHHHHHHCCCCCEEEEEEECCHHHCCCCCEEEECCCCEEEEECC
GIRVVIEQSAGHFCNFSDIDYSEAGAVIVASPEELFADSNVIVKVSPPQPEELPLFTPGQ
CEEEEEECCCCCCCCCCCCCCCCCCEEEEECHHHHHCCCCEEEEECCCCCCCCCCCCCHH
MLISALHLGTVSRHVIETLLEKNITALGFEFIETKDGELPIVRTLSEIAGSLAIQTAAKY
HHHHHHHHHHHHHHHHHHHHHCCCHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
LETGYGGSGILLGGIAGVPPAHVTIVGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFE
HHCCCCCCCEEECCCCCCCCCEEEEEECCCHHHEEHHHHHCCCCEEEEEHHHHHHHHHHH
AFFNRHLVTAIANDHYIAEIARFSDVMIGALSPKQKIIKPLVSEQVVKSMKPGSVIIDVS
HHHCCCEEEEECCCHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEE
IDQGACFSTSRHTSHTNPIYVKHGVTHYCVPNIPSAVAKTASFALTNTLLPFLLKLSEHE
ECCCCCCCCCCCCCCCCCEEEECCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
TISDILWKSHSLRKGTYIFKGYVTRKILAELLDFPFREIDMLLAAS
HHHHHHHCCCCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2340274 [H]