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The map label for this gene is tolB [H]

Identifier: 119356690

GI number: 119356690

Start: 983486

End: 984814

Strand: Direct

Name: tolB [H]

Synonym: Cpha266_0859

Alternate gene names: 119356690

Gene position: 983486-984814 (Clockwise)

Preceding gene: 119356689

Following gene: 119356691

Centisome position: 31.38

GC content: 45.82

Gene sequence:

>1329_bases
ATGATTATTCGTGAAGAATTCTCCCGCAAAATGCCCGCCGTGTTTATCAAGGCACTCCTGATTCTATGGTGCTTTGTATC
ATTTCCTTCCTTTCTCTTTGCTTCTGAAACCGGCGAATATATTGCCATTCGCAAGTCTGGTGGAGGCAAGATTCCTCTGA
CCCTCGACAAGACCTTCGCAAAAGGTAATAAGGAGAGCGGATGGGCGGAAACCTTTGATTCTGCTGTACGAGAGGGGCTT
GATTATTCCGGATTGTTTTCAATGATACCTCCACCGATCAATGTAAGAGCCGATGGAGGCAAAGGCGGTGTGAATTTCAG
CGTACTTGGTTCTGTTGGTTCAGAGATTTATGCGGGAGGCCGTCTTACGAAAGAATCCGGCAGCGTCACTCTCGATATGG
AGGTATACGAGACGCTTGGCGGGAAACTGATCATGAAAAAAAGTTATGTGGGAAGTGAAGGCGATCTCCGAAAACAGGGT
AATGTATTTTCTGCCGATCTTATTGAGCTTTTGACCGGAAAAAAATCATTGTTTGGCAGCAAAATTGTTTTTGTGTCAAA
TAAAACAGGGTTCAAGGAGATCTATCAGTGCGATTTTAACGGGCAGAATATTGAGCAGCTTACCAGCACAAAATCGATAT
CCCTGACGCCCGGCTATTCTCCTGACGGGAGATATCTCGCCTTTACCGATTATACAACGGGAAGGCCTGCTTTGCATATC
AGAAGTCTCTCTGACAGGAAAGATACTGTTCTTGAAAAAAACGGTGTAAGTATCGATCCTGGTTGGAGAAATGGACGTGA
ATTGGCAACGACGCTGTCGTATGAGGGTGACCAGGAACTCTATTTATGCAAGGTTGACGGAACGGTTTCTCGCAGGCTTA
CGACGAGCAAGGGGATTGATCTGTCGCCGACCTTTTCGCCTGACGGTTCCAGAATGGCATTTGTTTCTTCAAGGAACGGA
CTGCCCCAGATTTTTATTATGGATGTATCCTCCGGGTTAACACGGCGCCTGACCTACAGCGGCAGGTACAATACACAGCC
TTCATGGTCACCAGGCGGTGATAAAATTGCATATTCCACATGGGAAAAAAGCGGGGAAATCAATATATTTACTATTAATG
CCGACGGCACGGGGTTGAAGAAGCTTACAAGTGGTTCAAGAGAAAATGAAGCTCCCTCATGGTCGCCGGATGGCAGTATG
ATTGTGTTTGCGTCTAATCGTCAGGGAAATAAGAAATTGTTTGTGATGGGTTCCGGTGGGGAAAATCAGAAACGTTTATT
ACAAATGGACGGTGAACAGATGCAACCATCCTGGTCTTTATTTCGTTAG

Upstream 100 bases:

>100_bases
CGTCTTTAATGCGTTAATTTGTGATTAATGAAGAATTTTTTGTTCTCTCAAAAATATTTTTTAGTATTAGGGTTAGTATT
AATAGTTAATTGCCGTTACG

Downstream 100 bases:

>100_bases
TAGTATTCTTAGTAATAACCATAAAAAGGGGGAATCATGAGAACTGTAAAACCTTTACTTAAAAGCATTTTTATTCCGGG
CATGCTTTTTCTTGGAGCCT

Product: WD40 domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 442; Mature: 442

Protein sequence:

>442_residues
MIIREEFSRKMPAVFIKALLILWCFVSFPSFLFASETGEYIAIRKSGGGKIPLTLDKTFAKGNKESGWAETFDSAVREGL
DYSGLFSMIPPPINVRADGGKGGVNFSVLGSVGSEIYAGGRLTKESGSVTLDMEVYETLGGKLIMKKSYVGSEGDLRKQG
NVFSADLIELLTGKKSLFGSKIVFVSNKTGFKEIYQCDFNGQNIEQLTSTKSISLTPGYSPDGRYLAFTDYTTGRPALHI
RSLSDRKDTVLEKNGVSIDPGWRNGRELATTLSYEGDQELYLCKVDGTVSRRLTTSKGIDLSPTFSPDGSRMAFVSSRNG
LPQIFIMDVSSGLTRRLTYSGRYNTQPSWSPGGDKIAYSTWEKSGEINIFTINADGTGLKKLTSGSRENEAPSWSPDGSM
IVFASNRQGNKKLFVMGSGGENQKRLLQMDGEQMQPSWSLFR

Sequences:

>Translated_442_residues
MIIREEFSRKMPAVFIKALLILWCFVSFPSFLFASETGEYIAIRKSGGGKIPLTLDKTFAKGNKESGWAETFDSAVREGL
DYSGLFSMIPPPINVRADGGKGGVNFSVLGSVGSEIYAGGRLTKESGSVTLDMEVYETLGGKLIMKKSYVGSEGDLRKQG
NVFSADLIELLTGKKSLFGSKIVFVSNKTGFKEIYQCDFNGQNIEQLTSTKSISLTPGYSPDGRYLAFTDYTTGRPALHI
RSLSDRKDTVLEKNGVSIDPGWRNGRELATTLSYEGDQELYLCKVDGTVSRRLTTSKGIDLSPTFSPDGSRMAFVSSRNG
LPQIFIMDVSSGLTRRLTYSGRYNTQPSWSPGGDKIAYSTWEKSGEINIFTINADGTGLKKLTSGSRENEAPSWSPDGSM
IVFASNRQGNKKLFVMGSGGENQKRLLQMDGEQMQPSWSLFR
>Mature_442_residues
MIIREEFSRKMPAVFIKALLILWCFVSFPSFLFASETGEYIAIRKSGGGKIPLTLDKTFAKGNKESGWAETFDSAVREGL
DYSGLFSMIPPPINVRADGGKGGVNFSVLGSVGSEIYAGGRLTKESGSVTLDMEVYETLGGKLIMKKSYVGSEGDLRKQG
NVFSADLIELLTGKKSLFGSKIVFVSNKTGFKEIYQCDFNGQNIEQLTSTKSISLTPGYSPDGRYLAFTDYTTGRPALHI
RSLSDRKDTVLEKNGVSIDPGWRNGRELATTLSYEGDQELYLCKVDGTVSRRLTTSKGIDLSPTFSPDGSRMAFVSSRNG
LPQIFIMDVSSGLTRRLTYSGRYNTQPSWSPGGDKIAYSTWEKSGEINIFTINADGTGLKKLTSGSRENEAPSWSPDGSM
IVFASNRQGNKKLFVMGSGGENQKRLLQMDGEQMQPSWSLFR

Specific function: Involved in the tonB-independent uptake of proteins [H]

COG id: COG0823

COG function: function code U; Periplasmic component of the Tol biopolymer transport system

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tolB family [H]

Homologues:

Organism=Escherichia coli, GI1786961, Length=342, Percent_Identity=26.9005847953216, Blast_Score=121, Evalue=9e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011659
- InterPro:   IPR014167
- InterPro:   IPR007195
- InterPro:   IPR015943 [H]

Pfam domain/function: PF07676 PD40; PF04052 TolB_N [H]

EC number: NA

Molecular weight: Translated: 48459; Mature: 48459

Theoretical pI: Translated: 9.40; Mature: 9.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIREEFSRKMPAVFIKALLILWCFVSFPSFLFASETGEYIAIRKSGGGKIPLTLDKTFA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCEEEEEEEHHHC
KGNKESGWAETFDSAVREGLDYSGLFSMIPPPINVRADGGKGGVNFSVLGSVGSEIYAGG
CCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCCCCEEEEEECCCCHHCCCC
RLTKESGSVTLDMEVYETLGGKLIMKKSYVGSEGDLRKQGNVFSADLIELLTGKKSLFGS
EEEECCCCEEEEEHHHHHCCCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHCCCHHHCCC
KIVFVSNKTGFKEIYQCDFNGQNIEQLTSTKSISLTPGYSPDGRYLAFTDYTTGRPALHI
EEEEEECCCCCHHHEEECCCCCCHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCCEEEE
RSLSDRKDTVLEKNGVSIDPGWRNGRELATTLSYEGDQELYLCKVDGTVSRRLTTSKGID
ECCCCCCHHHEECCCCEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEECCCCCC
LSPTFSPDGSRMAFVSSRNGLPQIFIMDVSSGLTRRLTYSGRYNTQPSWSPGGDKIAYST
CCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEEE
WEKSGEINIFTINADGTGLKKLTSGSRENEAPSWSPDGSMIVFASNRQGNKKLFVMGSGG
CCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCC
ENQKRLLQMDGEQMQPSWSLFR
CCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIIREEFSRKMPAVFIKALLILWCFVSFPSFLFASETGEYIAIRKSGGGKIPLTLDKTFA
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEECCCCEEEEEEEHHHC
KGNKESGWAETFDSAVREGLDYSGLFSMIPPPINVRADGGKGGVNFSVLGSVGSEIYAGG
CCCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCCCCEEEEEECCCCHHCCCC
RLTKESGSVTLDMEVYETLGGKLIMKKSYVGSEGDLRKQGNVFSADLIELLTGKKSLFGS
EEEECCCCEEEEEHHHHHCCCEEEEEECCCCCCCCCHHCCCCHHHHHHHHHCCCHHHCCC
KIVFVSNKTGFKEIYQCDFNGQNIEQLTSTKSISLTPGYSPDGRYLAFTDYTTGRPALHI
EEEEEECCCCCHHHEEECCCCCCHHHHHCCCEEEECCCCCCCCCEEEEEECCCCCCEEEE
RSLSDRKDTVLEKNGVSIDPGWRNGRELATTLSYEGDQELYLCKVDGTVSRRLTTSKGID
ECCCCCCHHHEECCCCEECCCCCCCCEEEEEECCCCCCEEEEEEECCCCEEEEECCCCCC
LSPTFSPDGSRMAFVSSRNGLPQIFIMDVSSGLTRRLTYSGRYNTQPSWSPGGDKIAYST
CCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCEEEEEECCCCCCCCCCCCCCCEEEEEE
WEKSGEINIFTINADGTGLKKLTSGSRENEAPSWSPDGSMIVFASNRQGNKKLFVMGSGG
CCCCCCEEEEEEECCCCCHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEEECCC
ENQKRLLQMDGEQMQPSWSLFR
CCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA