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The map label for this gene is pab [H]

Identifier: 119356336

GI number: 119356336

Start: 547701

End: 549548

Strand: Direct

Name: pab [H]

Synonym: Cpha266_0499

Alternate gene names: 119356336

Gene position: 547701-549548 (Clockwise)

Preceding gene: 119356335

Following gene: 119356337

Centisome position: 17.48

GC content: 50.27

Gene sequence:

>1848_bases
ATGCGTGATCGGGAATCTTGCAGGATTCAGCGGCTTCTTCTCCATGAGGGGACAGTCTGGCTGGACGAATCGTATGGTGC
TCGACATGAGGGCGAAAGCCTGCTTTTTTCCGAACCTCTTGAGATGCTCGCTCTTTTTTCGGCAAGCGGTATCAGGGAGT
TTTTTACTCTTCTCGAACAAAAACTCGACAGCGGGTATTGGCTTGCCGGATGGATGGGCTATGAGGCAGGATACGGTTTT
GAGTCGGAACGCTTTCTTGCGAACTGCGATCCAGAGAGAGCTGCGCCTCTTGCCTGGTTTGGCGTTTATCGGCCCCCGGA
GCGATTTGCCTCTATTGTGAGCGAGAGGATGTTTTCTCAGGTAGCTGTCGATGAACCGTTCATGATCAGCGATTTTCGTT
TTAATCGCACTCCTGCCGAGTATTTTCAAGATGTTGAGAGGGTGAAACGGGAGATTGCCAAAGGAAATGTTTATCAGGTT
AACGTTACCGGCCGGTTTCGTTTTTCTTTTCATGGTTCAGCTCAGGCATTGTTCGGTGCGTTGTATCCGCAGCAGCCTTC
GGTGTATTCCGCTTTTATCAATACCGGTCGGCATCAGGTGCTCTCTTTTTCTCCCGAGCTTTTTTTTCGGCGCCGGGCTT
GTACGATTGAAGCTATGCCGATGAAAGGGACGGCTCCGAGAAGCGGCGTTGTTGAAGAAGATAATCGACTGAAGAGGCAA
TTATCGCTCTGCGAGAAGAATCGGGCTGAAAACCTGATGATTGTCGATCTGTTGCGTAACGATCTTGGCAGAATATGCAG
ATCAGGTTCAGTTGAGGTTTCGGGGATGTTTGCCACTGAGACCTATCCTACGCTTCACCAGATGGTGTCAACTATTCGCG
GGGAACTGAAGGATGAAAACGGTCTTTTCGAGACGTTTCGCGCTCTGTATCCCTGCGGTTCCATTACGGGAGCGCCAAAA
ATCAGCGCAATGCAGTTGATCCGTGAACTTGAGCCGGGCTTGAGGGGGTGCTACACCGGTACCATCGGGTATATCAATCC
TCGGAGAGATATGGTTTTCAGTGTTGCGATTCGTACGCTTGAACTGTCCGGCAATGAGGGCGTCTATGGTTCGGGCGGCG
GCATCGTCTGGGATTCCGATCCGGAGGAGGAGTACCAGGAGTGCATGCTGAAGGCAAAAATTCTTGATGATGTTACCGCA
GAGAGCGTTGAGCTGTTTGAGAGCATGCTTTTTTCCGGCAGATTTCTCTGGATGCAGGAGCATCTTGGACGGCTTGCGGC
TTCGGCAAGAGTTCTCGGATTTGCTTTCGATGCTGCAGAGGCTGCAGCCCGACTTGCGGCCCTTGCTGATATTCTTTTCA
AGGCAGGCGGACGTTTCAAGGTCAGACTCGCTCTTGAAAAAAACGGGCGGATGGCCATCAGCTATGAATCGCTGCTGTCT
GATACAGGTCGCGTTCCCCTGAAGCTCTCTCTTGCGGATGGATTTATCGACTCATCAAATTCGCTTCGATTTCATAAAAC
CAGTTCGCGAAAACGGTACGAACGGTATTACCGGAAAGCTCTTGAGAGCGGTTATGACGAGGTTGTGTTTCTCAATGAAC
GCCAGGAGGTGACGGAAGGGGCGATCAGCAACATTATTATTCTCAAAAGCCGACGCTATGTTACTCCCTCTCTTGGTTCA
GGATTGCTTGACGGCATTTATCGACGTTATTTTCTTTCTCTTCATCCGAATGCTTCAGAACAAGTGCTCACGCTGAAGGA
TCTTTTCGAGGCTGATCAGGTTTTTATCTGCAATTCGGTTCGAGGATTGCGTCCCGTCGTGTTCGATGGGTTTGTTATCT
CCATGTAA

Upstream 100 bases:

>100_bases
CACCTTGAACCCGATATCGAGATCTGGGCTGCCGATCAACTGAAGTCCTGGCTTGAAATGGTTTTGTCGCGTTCAATCGT
TATCCGCCCCCGCTCTGAGC

Downstream 100 bases:

>100_bases
TGCTTCATAATAGGGTTAAATGGCCGTATATTACAGCCAGAGGAATAGATTCCGCCATTCACAAACTCATTGTTTACTAC
TATGCGAGACCATACTCCTG

Product: para-aminobenzoate synthase, subunit I

Products: NA

Alternate protein names: P-aminobenzoic acid synthase; PABA synthase [H]

Number of amino acids: Translated: 615; Mature: 615

Protein sequence:

>615_residues
MRDRESCRIQRLLLHEGTVWLDESYGARHEGESLLFSEPLEMLALFSASGIREFFTLLEQKLDSGYWLAGWMGYEAGYGF
ESERFLANCDPERAAPLAWFGVYRPPERFASIVSERMFSQVAVDEPFMISDFRFNRTPAEYFQDVERVKREIAKGNVYQV
NVTGRFRFSFHGSAQALFGALYPQQPSVYSAFINTGRHQVLSFSPELFFRRRACTIEAMPMKGTAPRSGVVEEDNRLKRQ
LSLCEKNRAENLMIVDLLRNDLGRICRSGSVEVSGMFATETYPTLHQMVSTIRGELKDENGLFETFRALYPCGSITGAPK
ISAMQLIRELEPGLRGCYTGTIGYINPRRDMVFSVAIRTLELSGNEGVYGSGGGIVWDSDPEEEYQECMLKAKILDDVTA
ESVELFESMLFSGRFLWMQEHLGRLAASARVLGFAFDAAEAAARLAALADILFKAGGRFKVRLALEKNGRMAISYESLLS
DTGRVPLKLSLADGFIDSSNSLRFHKTSSRKRYERYYRKALESGYDEVVFLNERQEVTEGAISNIIILKSRRYVTPSLGS
GLLDGIYRRYFLSLHPNASEQVLTLKDLFEADQVFICNSVRGLRPVVFDGFVISM

Sequences:

>Translated_615_residues
MRDRESCRIQRLLLHEGTVWLDESYGARHEGESLLFSEPLEMLALFSASGIREFFTLLEQKLDSGYWLAGWMGYEAGYGF
ESERFLANCDPERAAPLAWFGVYRPPERFASIVSERMFSQVAVDEPFMISDFRFNRTPAEYFQDVERVKREIAKGNVYQV
NVTGRFRFSFHGSAQALFGALYPQQPSVYSAFINTGRHQVLSFSPELFFRRRACTIEAMPMKGTAPRSGVVEEDNRLKRQ
LSLCEKNRAENLMIVDLLRNDLGRICRSGSVEVSGMFATETYPTLHQMVSTIRGELKDENGLFETFRALYPCGSITGAPK
ISAMQLIRELEPGLRGCYTGTIGYINPRRDMVFSVAIRTLELSGNEGVYGSGGGIVWDSDPEEEYQECMLKAKILDDVTA
ESVELFESMLFSGRFLWMQEHLGRLAASARVLGFAFDAAEAAARLAALADILFKAGGRFKVRLALEKNGRMAISYESLLS
DTGRVPLKLSLADGFIDSSNSLRFHKTSSRKRYERYYRKALESGYDEVVFLNERQEVTEGAISNIIILKSRRYVTPSLGS
GLLDGIYRRYFLSLHPNASEQVLTLKDLFEADQVFICNSVRGLRPVVFDGFVISM
>Mature_615_residues
MRDRESCRIQRLLLHEGTVWLDESYGARHEGESLLFSEPLEMLALFSASGIREFFTLLEQKLDSGYWLAGWMGYEAGYGF
ESERFLANCDPERAAPLAWFGVYRPPERFASIVSERMFSQVAVDEPFMISDFRFNRTPAEYFQDVERVKREIAKGNVYQV
NVTGRFRFSFHGSAQALFGALYPQQPSVYSAFINTGRHQVLSFSPELFFRRRACTIEAMPMKGTAPRSGVVEEDNRLKRQ
LSLCEKNRAENLMIVDLLRNDLGRICRSGSVEVSGMFATETYPTLHQMVSTIRGELKDENGLFETFRALYPCGSITGAPK
ISAMQLIRELEPGLRGCYTGTIGYINPRRDMVFSVAIRTLELSGNEGVYGSGGGIVWDSDPEEEYQECMLKAKILDDVTA
ESVELFESMLFSGRFLWMQEHLGRLAASARVLGFAFDAAEAAARLAALADILFKAGGRFKVRLALEKNGRMAISYESLLS
DTGRVPLKLSLADGFIDSSNSLRFHKTSSRKRYERYYRKALESGYDEVVFLNERQEVTEGAISNIIILKSRRYVTPSLGS
GLLDGIYRRYFLSLHPNASEQVLTLKDLFEADQVFICNSVRGLRPVVFDGFVISM

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=338, Percent_Identity=36.3905325443787, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI1787518, Length=267, Percent_Identity=32.2097378277154, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI87082077, Length=204, Percent_Identity=28.921568627451, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1786809, Length=223, Percent_Identity=26.9058295964126, Blast_Score=75, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320935, Length=275, Percent_Identity=32.3636363636364, Blast_Score=150, Evalue=8e-37,
Organism=Saccharomyces cerevisiae, GI6324361, Length=286, Percent_Identity=27.6223776223776, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR006805
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR015890
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR005802
- InterPro:   IPR006221 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind; PF00117 GATase [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 69526; Mature: 69526

Theoretical pI: Translated: 6.35; Mature: 6.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDRESCRIQRLLLHEGTVWLDESYGARHEGESLLFSEPLEMLALFSASGIREFFTLLEQ
CCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KLDSGYWLAGWMGYEAGYGFESERFLANCDPERAAPLAWFGVYRPPERFASIVSERMFSQ
HHCCCEEEEEEECCCCCCCCCCCCEEECCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHH
VAVDEPFMISDFRFNRTPAEYFQDVERVKREIAKGNVYQVNVTGRFRFSFHGSAQALFGA
HHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCHHHHHHH
LYPQQPSVYSAFINTGRHQVLSFSPELFFRRRACTIEAMPMKGTAPRSGVVEEDNRLKRQ
CCCCCCHHHHHHHHCCCHHEEECCHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHH
LSLCEKNRAENLMIVDLLRNDLGRICRSGSVEVSGMFATETYPTLHQMVSTIRGELKDEN
HHHHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCC
GLFETFRALYPCGSITGAPKISAMQLIRELEPGLRGCYTGTIGYINPRRDMVFSVAIRTL
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHEEEEEEE
ELSGNEGVYGSGGGIVWDSDPEEEYQECMLKAKILDDVTAESVELFESMLFSGRFLWMQE
EECCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HLGRLAASARVLGFAFDAAEAAARLAALADILFKAGGRFKVRLALEKNGRMAISYESLLS
HHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHC
DTGRVPLKLSLADGFIDSSNSLRFHKTSSRKRYERYYRKALESGYDEVVFLNERQEVTEG
CCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHH
AISNIIILKSRRYVTPSLGSGLLDGIYRRYFLSLHPNASEQVLTLKDLFEADQVFICNSV
HHCCEEEEECCCEECCCCCCHHHHHHHHHHEEEECCCCCCCEEEHHHHHCCCCEEEECCC
RGLRPVVFDGFVISM
CCCCCEEECCEEECC
>Mature Secondary Structure
MRDRESCRIQRLLLHEGTVWLDESYGARHEGESLLFSEPLEMLALFSASGIREFFTLLEQ
CCCHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHH
KLDSGYWLAGWMGYEAGYGFESERFLANCDPERAAPLAWFGVYRPPERFASIVSERMFSQ
HHCCCEEEEEEECCCCCCCCCCCCEEECCCHHHCCCEEEEECCCCHHHHHHHHHHHHHHH
VAVDEPFMISDFRFNRTPAEYFQDVERVKREIAKGNVYQVNVTGRFRFSFHGSAQALFGA
HHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEECCCHHHHHHH
LYPQQPSVYSAFINTGRHQVLSFSPELFFRRRACTIEAMPMKGTAPRSGVVEEDNRLKRQ
CCCCCCHHHHHHHHCCCHHEEECCHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHH
LSLCEKNRAENLMIVDLLRNDLGRICRSGSVEVSGMFATETYPTLHQMVSTIRGELKDEN
HHHHHHCCCCCEEEHHHHHHHHHHHHCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCCCC
GLFETFRALYPCGSITGAPKISAMQLIRELEPGLRGCYTGTIGYINPRRDMVFSVAIRTL
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCCHHHHHEEEEEEE
ELSGNEGVYGSGGGIVWDSDPEEEYQECMLKAKILDDVTAESVELFESMLFSGRFLWMQE
EECCCCCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
HLGRLAASARVLGFAFDAAEAAARLAALADILFKAGGRFKVRLALEKNGRMAISYESLLS
HHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEHHHHHC
DTGRVPLKLSLADGFIDSSNSLRFHKTSSRKRYERYYRKALESGYDEVVFLNERQEVTEG
CCCCCCEEEEECCCCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHH
AISNIIILKSRRYVTPSLGSGLLDGIYRRYFLSLHPNASEQVLTLKDLFEADQVFICNSV
HHCCEEEEECCCEECCCCCCHHHHHHHHHHEEEECCCCCCCEEEHHHHHCCCCEEEECCC
RGLRPVVFDGFVISM
CCCCCEEECCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8472954 [H]