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The map label for this gene is era [H]

Identifier: 119356257

GI number: 119356257

Start: 463386

End: 464303

Strand: Reverse

Name: era [H]

Synonym: Cpha266_0419

Alternate gene names: 119356257

Gene position: 464303-463386 (Counterclockwise)

Preceding gene: 119356259

Following gene: 119356254

Centisome position: 14.82

GC content: 45.1

Gene sequence:

>918_bases
ATGGATGCTTCTTCTTTCTCCTGCGGGTTCGCCGTCATCATTGGCGCACCGAATGCGGGCAAATCCACCCTGCTTAACAA
GCTGCTCGACTACAAACTATCCATTGTAACGCCTAAACCGCAAACAACAAGAAAAAGAATAACCGGAATATACCATAAAG
ACCAGTGCCAGATAATTTTTCTTGATACTCCGGGCATTATGAAGCCGCAACAAAAGCTCCATGAATCCATGCTTGAAATA
ACCCGAGCAACGCTGAAGGATGCAGATGTTGTTCTTGCACTGCTGCCTTATTCCAGACAAAGCGGATCGGTTGACCTTGA
ATTTACCGAAGATCTATTTTCCTCATGGCTGAATCCTTCAGGAAAACCTGTTATTGCCGTTCTGAACAAAAGTGATCTGG
TCTCTGCAGAAGCGAAGCGAACATGCGAAAGCGTTATTCAGAACAGTTTTCATCCCAAAGCCGTTCTTTCAATAAGCGCG
CAGCTTGGAAATAACATCGAAGGATTAATCAGTGCACTTAAACCATTTCTCCCGCTTAAGGAACCACTCTACCCTGAAGA
GACCCTGAGCACTGATCCGGAAAGACTATTCGTCACTGAAATCATTCGTGAAAAGATATTTCTTCTCTATGGAAACGAGA
TCCCCTATGCTTCCGAGGTCATAATCGACGAGTTCAAGGAGCAGCATGAAAACGATCCATCAAGAAAAGACCTTATCAGA
TGTTCCATTATTGTAGAACGTGACAGCCAGAAACAGATCCTGATCGGCAGCAAGGGCGCCGCATTAAAAAAACTCGGGCA
GGCTGCGCGACTCGATATTGAAGAACTGCTCGGTCGTCCGGTGTTTCTTGAGCTTTTCATCAAGGTACGCAACGACTGGA
GAAAGAAAAACAATCTCCTGAAAAGCTACGGGTATTAA

Upstream 100 bases:

>100_bases
ATCTCATTTTCATTATCAAGAAGGAATCATTAGTATAGAAACGTACCTTATGCTACAGGAACGTTCCTTATGCTCTTTTT
ATCCCGTTAACCACTGAATC

Downstream 100 bases:

>100_bases
AAAAAAAGCCCCCCCTGTTGAGGGGGAGGCTTTATTGGATAATCAACGTACAGAAAAAAACCACGCACTGGCGGCTATTT
TGCCTCACCGCTTTTTTTCT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MDASSFSCGFAVIIGAPNAGKSTLLNKLLDYKLSIVTPKPQTTRKRITGIYHKDQCQIIFLDTPGIMKPQQKLHESMLEI
TRATLKDADVVLALLPYSRQSGSVDLEFTEDLFSSWLNPSGKPVIAVLNKSDLVSAEAKRTCESVIQNSFHPKAVLSISA
QLGNNIEGLISALKPFLPLKEPLYPEETLSTDPERLFVTEIIREKIFLLYGNEIPYASEVIIDEFKEQHENDPSRKDLIR
CSIIVERDSQKQILIGSKGAALKKLGQAARLDIEELLGRPVFLELFIKVRNDWRKKNNLLKSYGY

Sequences:

>Translated_305_residues
MDASSFSCGFAVIIGAPNAGKSTLLNKLLDYKLSIVTPKPQTTRKRITGIYHKDQCQIIFLDTPGIMKPQQKLHESMLEI
TRATLKDADVVLALLPYSRQSGSVDLEFTEDLFSSWLNPSGKPVIAVLNKSDLVSAEAKRTCESVIQNSFHPKAVLSISA
QLGNNIEGLISALKPFLPLKEPLYPEETLSTDPERLFVTEIIREKIFLLYGNEIPYASEVIIDEFKEQHENDPSRKDLIR
CSIIVERDSQKQILIGSKGAALKKLGQAARLDIEELLGRPVFLELFIKVRNDWRKKNNLLKSYGY
>Mature_305_residues
MDASSFSCGFAVIIGAPNAGKSTLLNKLLDYKLSIVTPKPQTTRKRITGIYHKDQCQIIFLDTPGIMKPQQKLHESMLEI
TRATLKDADVVLALLPYSRQSGSVDLEFTEDLFSSWLNPSGKPVIAVLNKSDLVSAEAKRTCESVIQNSFHPKAVLSISA
QLGNNIEGLISALKPFLPLKEPLYPEETLSTDPERLFVTEIIREKIFLLYGNEIPYASEVIIDEFKEQHENDPSRKDLIR
CSIIVERDSQKQILIGSKGAALKKLGQAARLDIEELLGRPVFLELFIKVRNDWRKKNNLLKSYGY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=325, Percent_Identity=26.7692307692308, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788919, Length=300, Percent_Identity=34.6666666666667, Blast_Score=177, Evalue=9e-46,
Organism=Saccharomyces cerevisiae, GI6323665, Length=167, Percent_Identity=34.7305389221557, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34245; Mature: 34245

Theoretical pI: Translated: 8.29; Mature: 8.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDASSFSCGFAVIIGAPNAGKSTLLNKLLDYKLSIVTPKPQTTRKRITGIYHKDQCQIIF
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHCCEECCCEEEEE
LDTPGIMKPQQKLHESMLEITRATLKDADVVLALLPYSRQSGSVDLEFTEDLFSSWLNPS
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHCCCC
GKPVIAVLNKSDLVSAEAKRTCESVIQNSFHPKAVLSISAQLGNNIEGLISALKPFLPLK
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHCCCHHHHHHHHHHCCCCC
EPLYPEETLSTDPERLFVTEIIREKIFLLYGNEIPYASEVIIDEFKEQHENDPSRKDLIR
CCCCCCHHCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHEE
CSIIVERDSQKQILIGSKGAALKKLGQAARLDIEELLGRPVFLELFIKVRNDWRKKNNLL
EEEEEECCCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KSYGY
HHCCC
>Mature Secondary Structure
MDASSFSCGFAVIIGAPNAGKSTLLNKLLDYKLSIVTPKPQTTRKRITGIYHKDQCQIIF
CCCCCCCCCEEEEEECCCCCHHHHHHHHHHCEEEEECCCCHHHHHHHHCCEECCCEEEEE
LDTPGIMKPQQKLHESMLEITRATLKDADVVLALLPYSRQSGSVDLEFTEDLFSSWLNPS
ECCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEHHHHHHHHCCCC
GKPVIAVLNKSDLVSAEAKRTCESVIQNSFHPKAVLSISAQLGNNIEGLISALKPFLPLK
CCEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHCCCHHHHHHHHHHCCCCC
EPLYPEETLSTDPERLFVTEIIREKIFLLYGNEIPYASEVIIDEFKEQHENDPSRKDLIR
CCCCCCHHCCCCHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHHHHHCCCCCHHHHEE
CSIIVERDSQKQILIGSKGAALKKLGQAARLDIEELLGRPVFLELFIKVRNDWRKKNNLL
EEEEEECCCCCEEEEECCCHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHH
KSYGY
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA