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The map label for this gene is bioD [H]

Identifier: 119355966

GI number: 119355966

Start: 135728

End: 136402

Strand: Direct

Name: bioD [H]

Synonym: Cpha266_0116

Alternate gene names: 119355966

Gene position: 135728-136402 (Clockwise)

Preceding gene: 119355965

Following gene: 119355967

Centisome position: 4.33

GC content: 52.44

Gene sequence:

>675_bases
ATGAAAGGCAGCGTAACGGCAATATCCGGCATAGGCACCGGGGTTGGAAAAACCGTTGTGACCGGTCTTCTGGCTCAAGG
GCTTCAGAAATGCGATCGAAAAGTGGTAACGCAGAAAATTGTGCAGACTGGTTGTACGGGCATCTCTTCCGATATTCTTG
AACACAGGCGTTTGATGGGTTCTTCCTTGATCGATGTCGATTATGAGGGGGTTACCTGTCCCTACTCTTTCGGTTATCCG
GCATCTCCGCATCTCGCGGCTCGCCTTGAAGGCGCCGCAGTAGAGGTGATGACTCTTCGACGGGCAACGTTTACCCTGCA
GAAGCAGTTCGATCATGTGCTTCTTGAAGGGGTTGGCGGCCTTCTGGTTCCCCTTGCCCCCGATCTCCTGTTTGCGGACT
ATATCAGGGACGCAGGCTATCCGCTTATTCTCGTTACCGCAACAGGGCTGGGGAGCATCAATCATACCCTCTTGTCGCTT
GAGGCTTGCATTGCAAGACGCATCACCCTTAAGGCCGTTATCTGCAACCGTTTCGGGGAAATCGATACCCTTATCGGCGA
CGATACGGTCGAAATGACGAGACATTACCTGAAAAAATACGGGTTACGCGCGCCGCTGTTCACGCTTGTCGGCGATACGT
TGGATTGCGGGTGTATCGAGTCACTTTTTTTATGA

Upstream 100 bases:

>100_bases
ATGAAAGATTTCTTCATCGATACAGGCAGGAGTTCTCCTCCGGCGGCAAGGTTTACCTGACCTATAATCCGCTCTACTGT
TGTTTCAGAAAACGTTTATC

Downstream 100 bases:

>100_bases
TCAATTTAACCCGATAAGGATCAATGACCTTGCCTTTGCCAGTTATAGATCTTGCTTTTGACCGGAGCCATATCTGGCAC
CCGTACACCTCGCTTGCCGA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MKGSVTAISGIGTGVGKTVVTGLLAQGLQKCDRKVVTQKIVQTGCTGISSDILEHRRLMGSSLIDVDYEGVTCPYSFGYP
ASPHLAARLEGAAVEVMTLRRATFTLQKQFDHVLLEGVGGLLVPLAPDLLFADYIRDAGYPLILVTATGLGSINHTLLSL
EACIARRITLKAVICNRFGEIDTLIGDDTVEMTRHYLKKYGLRAPLFTLVGDTLDCGCIESLFL

Sequences:

>Translated_224_residues
MKGSVTAISGIGTGVGKTVVTGLLAQGLQKCDRKVVTQKIVQTGCTGISSDILEHRRLMGSSLIDVDYEGVTCPYSFGYP
ASPHLAARLEGAAVEVMTLRRATFTLQKQFDHVLLEGVGGLLVPLAPDLLFADYIRDAGYPLILVTATGLGSINHTLLSL
EACIARRITLKAVICNRFGEIDTLIGDDTVEMTRHYLKKYGLRAPLFTLVGDTLDCGCIESLFL
>Mature_224_residues
MKGSVTAISGIGTGVGKTVVTGLLAQGLQKCDRKVVTQKIVQTGCTGISSDILEHRRLMGSSLIDVDYEGVTCPYSFGYP
ASPHLAARLEGAAVEVMTLRRATFTLQKQFDHVLLEGVGGLLVPLAPDLLFADYIRDAGYPLILVTATGLGSINHTLLSL
EACIARRITLKAVICNRFGEIDTLIGDDTVEMTRHYLKKYGLRAPLFTLVGDTLDCGCIESLFL

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=174, Percent_Identity=32.7586206896552, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472
- InterPro:   IPR002586 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24075; Mature: 24075

Theoretical pI: Translated: 6.99; Mature: 6.99

Prosite motif: PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
3.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSVTAISGIGTGVGKTVVTGLLAQGLQKCDRKVVTQKIVQTGCTGISSDILEHRRLMG
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
SSLIDVDYEGVTCPYSFGYPASPHLAARLEGAAVEVMTLRRATFTLQKQFDHVLLEGVGG
CCEEEECCCCEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LLVPLAPDLLFADYIRDAGYPLILVTATGLGSINHTLLSLEACIARRITLKAVICNRFGE
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDTLIGDDTVEMTRHYLKKYGLRAPLFTLVGDTLDCGCIESLFL
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure
MKGSVTAISGIGTGVGKTVVTGLLAQGLQKCDRKVVTQKIVQTGCTGISSDILEHRRLMG
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
SSLIDVDYEGVTCPYSFGYPASPHLAARLEGAAVEVMTLRRATFTLQKQFDHVLLEGVGG
CCEEEECCCCEECCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LLVPLAPDLLFADYIRDAGYPLILVTATGLGSINHTLLSLEACIARRITLKAVICNRFGE
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IDTLIGDDTVEMTRHYLKKYGLRAPLFTLVGDTLDCGCIESLFL
HHHHCCCCHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901 [H]