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The map label for this gene is rsmB [H]

Identifier: 118581643

GI number: 118581643

Start: 3561532

End: 3562890

Strand: Reverse

Name: rsmB [H]

Synonym: Ppro_3242

Alternate gene names: 118581643

Gene position: 3562890-3561532 (Counterclockwise)

Preceding gene: 118581644

Following gene: 118581642

Centisome position: 88.89

GC content: 66.59

Gene sequence:

>1359_bases
GTGAGCGCCCCCGACCTGAAGCGCTCCAACCCGCGCCAGTCGGCCTGCTCGGTCCTGCTGCGGATCCAGCGAGAGGGATG
CTATGCCGACCAGCTCATGGACCGCGAACTGGAGTCCGGCGGGCTTACCGGCCCTGACCGGGGCCTGTTCGCCGAACTGG
TCTTCGGCGCGCTACGTCGCCAGGGAACCCTGGACCACATCCTCTCCAGCCTGCTCACCCAGCCGCTCTCCCGGCTGGAA
CCGCAGGCGCTGATCCTCTTGCGGGTGGGGCTGTACCAGCTGGTCTACCTGGACCGAATCCCCGAATCAGCGGCGGTTAA
CGAGTCGGTCAATCTGGCCAAGAAAACCCTGCCCCGCGCCAGCGGGCTGGTGAACGCCGTGCTGCGCAATTACCTACGCC
GCGGGGATGACATCCCTTTCCCCGATCCGCTGGCGATGCCTGCCGAATCCATCGCCGCCCGCCATTCCCATCCTCTCTGG
CTGGTGAGGCAGTGGATCGACCAGTTGGGCGTTGAGGAGGCCGAGGCTCTGGCAGAGGCCTCGTCGCGCCAGGCGCCCCT
GGCCCTGCGCGCCAACACGCTGGCCATCAGTCGGGACGACCTGCTGGTGAAGTTTTCCACCAACGGCATCCAGGCCACTC
CCTGTCGCTTCTCTCCCCACGGCATCCTGGTGGAGGGCCGGCACCAGATTACCTCCCTGCCCGGCTTTCACGAGGGGCTC
TTCGCTGTTCAGGACGAGGCCTCCCAGATGGCGGGACTGCTTCTGGACCCGCGTCCGGGGGAGCGGATACTGGATGCCTG
CGCCGCGCCGGGGGGCAAGGCCACCCACTTGGCCCAGCTGATGAATGATCGCGGCGAGCTGCTGGCCATGGACGTCTCCG
GCGTCAAACTCCCCCTGATCCAGGAGAGCGCCCACCGGCTGGGAATCAGCATCATCCGTACCCGCAGGGCCGACCTGCTC
AACAGCGCGGCGTTTCCCGTCGACTCCTTCGACAGGGTCCTGCTGGACGCCCCCTGCTCCGGCCTGGGAGTCATCCGCCG
CAATCCCGAGGCCAAATGGCGGCTCCGGCCGGAGGATCTCACCCGTTTGGCCGAGACCCAACGGCGCATGTTCGCCAACG
CGGTCAGAATGCTCAAGCCGGGCGGCAGGCTGGTCTATTCCACCTGCTCCACCAGCCGGGAGGAGAATGAGGCCGTGCTG
CACGCTTTCCTCTCCCGCCAGGATGGCGTGATTCTGGAAGACCTGAACCAGGTCTACCCCTGCTGGAGCGAACTGTTCAC
CCGGGAGGGGATGCTGCGTTCCTGGCCCCATTGTCATGGCATGGACGGCTTCTTCGCCGCCAGGCTCATCAAGCGCTAA

Upstream 100 bases:

>100_bases
ACCCCCTGACCGGTGGTGGCCTGATGACGCTCTTCTCCACCCATCCCCCCATGCAGGAGCGCATCGCGCGTCTGCAGGAG
ATGGCCCGGATGGGCCGCTC

Downstream 100 bases:

>100_bases
GTACCACCAACTACACATCAGGGAGTATTGCACCCATGAAGAAGATAGCCCCTTCGATCCTCTCCGCCGATTTTTCCCGG
CTGGGCGAAGAGATCCGCAG

Product: sun protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MSAPDLKRSNPRQSACSVLLRIQREGCYADQLMDRELESGGLTGPDRGLFAELVFGALRRQGTLDHILSSLLTQPLSRLE
PQALILLRVGLYQLVYLDRIPESAAVNESVNLAKKTLPRASGLVNAVLRNYLRRGDDIPFPDPLAMPAESIAARHSHPLW
LVRQWIDQLGVEEAEALAEASSRQAPLALRANTLAISRDDLLVKFSTNGIQATPCRFSPHGILVEGRHQITSLPGFHEGL
FAVQDEASQMAGLLLDPRPGERILDACAAPGGKATHLAQLMNDRGELLAMDVSGVKLPLIQESAHRLGISIIRTRRADLL
NSAAFPVDSFDRVLLDAPCSGLGVIRRNPEAKWRLRPEDLTRLAETQRRMFANAVRMLKPGGRLVYSTCSTSREENEAVL
HAFLSRQDGVILEDLNQVYPCWSELFTREGMLRSWPHCHGMDGFFAARLIKR

Sequences:

>Translated_452_residues
MSAPDLKRSNPRQSACSVLLRIQREGCYADQLMDRELESGGLTGPDRGLFAELVFGALRRQGTLDHILSSLLTQPLSRLE
PQALILLRVGLYQLVYLDRIPESAAVNESVNLAKKTLPRASGLVNAVLRNYLRRGDDIPFPDPLAMPAESIAARHSHPLW
LVRQWIDQLGVEEAEALAEASSRQAPLALRANTLAISRDDLLVKFSTNGIQATPCRFSPHGILVEGRHQITSLPGFHEGL
FAVQDEASQMAGLLLDPRPGERILDACAAPGGKATHLAQLMNDRGELLAMDVSGVKLPLIQESAHRLGISIIRTRRADLL
NSAAFPVDSFDRVLLDAPCSGLGVIRRNPEAKWRLRPEDLTRLAETQRRMFANAVRMLKPGGRLVYSTCSTSREENEAVL
HAFLSRQDGVILEDLNQVYPCWSELFTREGMLRSWPHCHGMDGFFAARLIKR
>Mature_451_residues
SAPDLKRSNPRQSACSVLLRIQREGCYADQLMDRELESGGLTGPDRGLFAELVFGALRRQGTLDHILSSLLTQPLSRLEP
QALILLRVGLYQLVYLDRIPESAAVNESVNLAKKTLPRASGLVNAVLRNYLRRGDDIPFPDPLAMPAESIAARHSHPLWL
VRQWIDQLGVEEAEALAEASSRQAPLALRANTLAISRDDLLVKFSTNGIQATPCRFSPHGILVEGRHQITSLPGFHEGLF
AVQDEASQMAGLLLDPRPGERILDACAAPGGKATHLAQLMNDRGELLAMDVSGVKLPLIQESAHRLGISIIRTRRADLLN
SAAFPVDSFDRVLLDAPCSGLGVIRRNPEAKWRLRPEDLTRLAETQRRMFANAVRMLKPGGRLVYSTCSTSREENEAVLH
AFLSRQDGVILEDLNQVYPCWSELFTREGMLRSWPHCHGMDGFFAARLIKR

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=324, Percent_Identity=33.9506172839506, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI76150623, Length=324, Percent_Identity=33.9506172839506, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI32698918, Length=167, Percent_Identity=41.9161676646707, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI270288818, Length=317, Percent_Identity=31.5457413249211, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI8922322, Length=312, Percent_Identity=31.4102564102564, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI23199998, Length=312, Percent_Identity=31.4102564102564, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI270288816, Length=312, Percent_Identity=31.4102564102564, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI39995082, Length=221, Percent_Identity=31.6742081447964, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI301336155, Length=221, Percent_Identity=31.6742081447964, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI11545785, Length=206, Percent_Identity=30.0970873786408, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI40316918, Length=171, Percent_Identity=32.7485380116959, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI2367212, Length=413, Percent_Identity=34.6246973365617, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI87081985, Length=278, Percent_Identity=36.6906474820144, Blast_Score=159, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI17536757, Length=324, Percent_Identity=31.4814814814815, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI71998419, Length=219, Percent_Identity=32.4200913242009, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI115534021, Length=219, Percent_Identity=32.4200913242009, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI25143471, Length=197, Percent_Identity=34.5177664974619, Blast_Score=87, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=310, Percent_Identity=30.6451612903226, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6319447, Length=184, Percent_Identity=29.8913043478261, Blast_Score=74, Evalue=5e-14,
Organism=Drosophila melanogaster, GI22024126, Length=316, Percent_Identity=31.9620253164557, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI24668781, Length=199, Percent_Identity=36.1809045226131, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21356513, Length=199, Percent_Identity=36.1809045226131, Blast_Score=122, Evalue=7e-28,
Organism=Drosophila melanogaster, GI21355201, Length=282, Percent_Identity=30.1418439716312, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356579, Length=241, Percent_Identity=24.4813278008299, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920494, Length=201, Percent_Identity=31.8407960199005, Blast_Score=87, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: 2.1.1.-

Molecular weight: Translated: 50073; Mature: 49942

Theoretical pI: Translated: 8.03; Mature: 8.03

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPDLKRSNPRQSACSVLLRIQREGCYADQLMDRELESGGLTGPDRGLFAELVFGALRR
CCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
QGTLDHILSSLLTQPLSRLEPQALILLRVGLYQLVYLDRIPESAAVNESVNLAKKTLPRA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCHH
SGLVNAVLRNYLRRGDDIPFPDPLAMPAESIAARHSHPLWLVRQWIDQLGVEEAEALAEA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHH
SSRQAPLALRANTLAISRDDLLVKFSTNGIQATPCRFSPHGILVEGRHQITSLPGFHEGL
HCCCCCEEEECCEEEEECCCEEEEEECCCEEECCCCCCCCCEEEECCHHHCCCCCHHHHH
FAVQDEASQMAGLLLDPRPGERILDACAAPGGKATHLAQLMNDRGELLAMDVSGVKLPLI
HHHHHHHHHHHCEEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCEEHHH
QESAHRLGISIIRTRRADLLNSAAFPVDSFDRVLLDAPCSGLGVIRRNPEAKWRLRPEDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEECCCCCCEEECHHHH
TRLAETQRRMFANAVRMLKPGGRLVYSTCSTSREENEAVLHAFLSRQDGVILEDLNQVYP
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
CWSELFTREGMLRSWPHCHGMDGFFAARLIKR
HHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
SAPDLKRSNPRQSACSVLLRIQREGCYADQLMDRELESGGLTGPDRGLFAELVFGALRR
CCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHC
QGTLDHILSSLLTQPLSRLEPQALILLRVGLYQLVYLDRIPESAAVNESVNLAKKTLPRA
CCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHCCHH
SGLVNAVLRNYLRRGDDIPFPDPLAMPAESIAARHSHPLWLVRQWIDQLGVEEAEALAEA
HHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCHHHHHHHHHH
SSRQAPLALRANTLAISRDDLLVKFSTNGIQATPCRFSPHGILVEGRHQITSLPGFHEGL
HCCCCCEEEECCEEEEECCCEEEEEECCCEEECCCCCCCCCEEEECCHHHCCCCCHHHHH
FAVQDEASQMAGLLLDPRPGERILDACAAPGGKATHLAQLMNDRGELLAMDVSGVKLPLI
HHHHHHHHHHHCEEECCCCCHHHHHHHCCCCCHHHHHHHHHCCCCCEEEEECCCCEEHHH
QESAHRLGISIIRTRRADLLNSAAFPVDSFDRVLLDAPCSGLGVIRRNPEAKWRLRPEDL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEECCCCCCEEECHHHH
TRLAETQRRMFANAVRMLKPGGRLVYSTCSTSREENEAVLHAFLSRQDGVILEDLNQVYP
HHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHH
CWSELFTREGMLRSWPHCHGMDGFFAARLIKR
HHHHHHHHCCHHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]