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The map label for this gene is htpX [H]

Identifier: 118581644

GI number: 118581644

Start: 3562887

End: 3563735

Strand: Reverse

Name: htpX [H]

Synonym: Ppro_3243

Alternate gene names: 118581644

Gene position: 3563735-3562887 (Counterclockwise)

Preceding gene: 118581646

Following gene: 118581643

Centisome position: 88.92

GC content: 63.96

Gene sequence:

>849_bases
ATGAACACACTGAAGACGACTTTCCTGATGGCGCTGCTTACGGTCATGATGGTCATGCTGGGGGGGGCGCTGGGGGGCAG
GAACGGCATGACCCTGGCTTTTGTCATGGCTGCCGGTATGAACTTCTTCTCCTACTGGTTTTCGGACAAGATGGTGCTCT
CCATGTATGGGGCGCATGAGATCAGCGAGCGGGACGATCCGCGCTTCTACGGCCTGGTGCGCCGCCTGGCCCAGCGGGCC
GGCCTGCCCATGCCCAAGGTGTATGTGATCGATTCCGATACCCCCAATGCCTTTGCCACGGGTCGTAATCCCGAGCACGC
CGCGGTGGCGGCCACCAGCGGCATCCTGCGCATCCTCAGCGAAGAGGAGTTGGCCGGGGTCATGGCCCACGAACTGGCCC
ACGTCAAGAACCGCGACATCCTGATCCAGACCATTGCAGCCACCTTTGCCGGCGCCATCACCTACATGGCCCACATGGCC
CAGTGGGGCGCCATGTTCGGCGGCCGGGGCGATGATGACGACGGTGGGGGCATGGGTGCGCTGGTGATGGCCATCCTGGC
ACCTCTGGCCGCCATGCTGGTGCAGATGGCCATCTCCCGCTCCCGCGAGTACGGTGCCGATGCAGGTGGAGCCAGCATCT
GCGGTAATCCGCTCTCCCTGGCCAATGCCCTGGCAAAGCTGGAGATGGGCAACCGCCAGATTCCCATGCATGCCAATGCC
GCCACGGCGCACATGTTCATCGTAAACCCCCTGACCGGTGGTGGCCTGATGACGCTCTTCTCCACCCATCCCCCCATGCA
GGAGCGCATCGCGCGTCTGCAGGAGATGGCCCGGATGGGCCGCTCGTGA

Upstream 100 bases:

>100_bases
GGTCCTATCTTCTCCCCCGCCCTTGCGCTTTGCGACCACAATCATTACTATTACGGGAACCGGAACGGCATCAACACCCG
CACGAAGTGAGGAACCGACT

Downstream 100 bases:

>100_bases
GCGCCCCCGACCTGAAGCGCTCCAACCCGCGCCAGTCGGCCTGCTCGGTCCTGCTGCGGATCCAGCGAGAGGGATGCTAT
GCCGACCAGCTCATGGACCG

Product: peptidase M48, Ste24p

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MNTLKTTFLMALLTVMMVMLGGALGGRNGMTLAFVMAAGMNFFSYWFSDKMVLSMYGAHEISERDDPRFYGLVRRLAQRA
GLPMPKVYVIDSDTPNAFATGRNPEHAAVAATSGILRILSEEELAGVMAHELAHVKNRDILIQTIAATFAGAITYMAHMA
QWGAMFGGRGDDDDGGGMGALVMAILAPLAAMLVQMAISRSREYGADAGGASICGNPLSLANALAKLEMGNRQIPMHANA
ATAHMFIVNPLTGGGLMTLFSTHPPMQERIARLQEMARMGRS

Sequences:

>Translated_282_residues
MNTLKTTFLMALLTVMMVMLGGALGGRNGMTLAFVMAAGMNFFSYWFSDKMVLSMYGAHEISERDDPRFYGLVRRLAQRA
GLPMPKVYVIDSDTPNAFATGRNPEHAAVAATSGILRILSEEELAGVMAHELAHVKNRDILIQTIAATFAGAITYMAHMA
QWGAMFGGRGDDDDGGGMGALVMAILAPLAAMLVQMAISRSREYGADAGGASICGNPLSLANALAKLEMGNRQIPMHANA
ATAHMFIVNPLTGGGLMTLFSTHPPMQERIARLQEMARMGRS
>Mature_282_residues
MNTLKTTFLMALLTVMMVMLGGALGGRNGMTLAFVMAAGMNFFSYWFSDKMVLSMYGAHEISERDDPRFYGLVRRLAQRA
GLPMPKVYVIDSDTPNAFATGRNPEHAAVAATSGILRILSEEELAGVMAHELAHVKNRDILIQTIAATFAGAITYMAHMA
QWGAMFGGRGDDDDGGGMGALVMAILAPLAAMLVQMAISRSREYGADAGGASICGNPLSLANALAKLEMGNRQIPMHANA
ATAHMFIVNPLTGGGLMTLFSTHPPMQERIARLQEMARMGRS

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=287, Percent_Identity=31.0104529616725, Blast_Score=102, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.-

Molecular weight: Translated: 30190; Mature: 30190

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
9.2 %Met     (Translated Protein)
9.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
9.2 %Met     (Mature Protein)
9.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTLKTTFLMALLTVMMVMLGGALGGRNGMTLAFVMAAGMNFFSYWFSDKMVLSMYGAHE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHH
ISERDDPRFYGLVRRLAQRAGLPMPKVYVIDSDTPNAFATGRNPEHAAVAATSGILRILS
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHH
EEELAGVMAHELAHVKNRDILIQTIAATFAGAITYMAHMAQWGAMFGGRGDDDDGGGMGA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LVMAILAPLAAMLVQMAISRSREYGADAGGASICGNPLSLANALAKLEMGNRQIPMHANA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
ATAHMFIVNPLTGGGLMTLFSTHPPMQERIARLQEMARMGRS
CEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNTLKTTFLMALLTVMMVMLGGALGGRNGMTLAFVMAAGMNFFSYWFSDKMVLSMYGAHE
CCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHH
ISERDDPRFYGLVRRLAQRAGLPMPKVYVIDSDTPNAFATGRNPEHAAVAATSGILRILS
CCCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCHHHHHHHHHHHHHHH
EEELAGVMAHELAHVKNRDILIQTIAATFAGAITYMAHMAQWGAMFGGRGDDDDGGGMGA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
LVMAILAPLAAMLVQMAISRSREYGADAGGASICGNPLSLANALAKLEMGNRQIPMHANA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCC
ATAHMFIVNPLTGGGLMTLFSTHPPMQERIARLQEMARMGRS
CEEEEEEEECCCCCCHHHHHCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA