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The map label for this gene is yhfN [H]

Identifier: 118581600

GI number: 118581600

Start: 3516089

End: 3517351

Strand: Reverse

Name: yhfN [H]

Synonym: Ppro_3199

Alternate gene names: 118581600

Gene position: 3517351-3516089 (Counterclockwise)

Preceding gene: 118581601

Following gene: 118581599

Centisome position: 87.76

GC content: 61.84

Gene sequence:

>1263_bases
TTGACTACGTTCGCCCTGCTCATTCTCTTCGTTGTCGAGACCGCCTTTGCCTACTGGTTGCGCCACATCAACCTGGAGCA
TCTCAAGCGCCACGGCATGGCCGTTCCCCCTGGGTTCGAGGGGGCCATCGACGAAGAGAAACTCCGCTCCAGCACTTCCT
ACACCCTTGACTCCAGCCGCCTGGGGCTGTGGGAGTCGCTCTTCAACAACCTGCTGCTGATCCTCTTCCTGTTCGGCGGC
CTGCTGACGCTGCTGGATGGTTTCGTGGCCGGCCTGACCCCCCTGCTCATGACCCACGGCATTTTCTTTTTCGTGGCCAT
GGTATGGGGACAGGCGGTGCTGGACATCCCCTTCGACCTCTACGGAACCTTCCGCATCGAGGCCCGCTACGGTTTCAACA
CCACCACCCCGCGGCTCTGGCTGGTGGATTTCCTCAAGTCCCAGGCCATCGGCACGCTGCTGCTGGTGTTTCTGCTGGGT
GCTGTCTTCTGGCTGATCCAGTGGAGCCCCGGCCGCTGGTGGGTATGGGTCTGGGGTTTCATGGCCGTTTTCAGCCTGTT
CATGATGCTCATCTCCCCCTATGTGGTCGAACCGCTGTTCAATACGTTCGAGCCGGTAACGGAAGAGGGGCTGGAGGACG
AGATCCGCAGCCTGATGGAGAAGGCGGGGCTGAAGGTGGGGCGGGTGATGCAGATGGATGCCTCGAAACGTAGCAGGCAC
TCCAACGCCTATTTCACCGGCATCGGTAAGGTGAAGCGCATCGTGCTCTACGACACCCTGATCCGGCAGATGAGTCATGG
CGAGATCGTGGCGGTCCTGGCCCACGAGATCGGCCACTGGAAGAAGGGGCATGTGTGGAAGCGCCTGCTCTGGGCGGAAC
TGATGGCGCTGGCCGGATCATGGCTCTTCTTTCAGCTGCTGAACTGGCCGGGATTGCCCGGTCTGCTGGGGTTGCCCCTA
TCCATTTCGCTGCCGGCCAGAATGGTCGTGGTCGGCTTCCTGGCGTCGCTGGCGCTGTTCCCGTTTGAGCCTCTCAGCGC
CTGGTATTCGCGCCGACACGAACGGGAGGCGGACCGCTTTGCCGCCGATCTGACCGGAAAGCCGCACGACCTGGCCTCGG
CCATGGTCAAGCTGTCGGTGGAGAATCTCTCCAACCTGTTCCCCCACCCCCTGTATGCCTGGTTTTACTACTCCCATCCA
CCGGCAGTGGAGCGAGTGCGGACGCTGCGGGAGATGACGGAATCCTCTCGGCGCCAGTCCTGA

Upstream 100 bases:

>100_bases
GGTATCGGCAAGTGTGTGAACGATATCGTCAACATGATCTCCTAGAACAGCGGAGGAAGGGGCCGCCAGACCGTGGCGGC
CCTGCTCACGGGAACAGCCA

Downstream 100 bases:

>100_bases
ACGGACGCCAGCCACGGTCCTCGGCTTTCCGGGGGGCTCCCCCGGGTCTGTGCCGGGATTATATCCGTTGACATAACCGT
GGAGTTTGGCTAATCTTTCA

Product: Ste24 endopeptidase

Products: NA

Alternate protein names: PSP23 [H]

Number of amino acids: Translated: 420; Mature: 419

Protein sequence:

>420_residues
MTTFALLILFVVETAFAYWLRHINLEHLKRHGMAVPPGFEGAIDEEKLRSSTSYTLDSSRLGLWESLFNNLLLILFLFGG
LLTLLDGFVAGLTPLLMTHGIFFFVAMVWGQAVLDIPFDLYGTFRIEARYGFNTTTPRLWLVDFLKSQAIGTLLLVFLLG
AVFWLIQWSPGRWWVWVWGFMAVFSLFMMLISPYVVEPLFNTFEPVTEEGLEDEIRSLMEKAGLKVGRVMQMDASKRSRH
SNAYFTGIGKVKRIVLYDTLIRQMSHGEIVAVLAHEIGHWKKGHVWKRLLWAELMALAGSWLFFQLLNWPGLPGLLGLPL
SISLPARMVVVGFLASLALFPFEPLSAWYSRRHEREADRFAADLTGKPHDLASAMVKLSVENLSNLFPHPLYAWFYYSHP
PAVERVRTLREMTESSRRQS

Sequences:

>Translated_420_residues
MTTFALLILFVVETAFAYWLRHINLEHLKRHGMAVPPGFEGAIDEEKLRSSTSYTLDSSRLGLWESLFNNLLLILFLFGG
LLTLLDGFVAGLTPLLMTHGIFFFVAMVWGQAVLDIPFDLYGTFRIEARYGFNTTTPRLWLVDFLKSQAIGTLLLVFLLG
AVFWLIQWSPGRWWVWVWGFMAVFSLFMMLISPYVVEPLFNTFEPVTEEGLEDEIRSLMEKAGLKVGRVMQMDASKRSRH
SNAYFTGIGKVKRIVLYDTLIRQMSHGEIVAVLAHEIGHWKKGHVWKRLLWAELMALAGSWLFFQLLNWPGLPGLLGLPL
SISLPARMVVVGFLASLALFPFEPLSAWYSRRHEREADRFAADLTGKPHDLASAMVKLSVENLSNLFPHPLYAWFYYSHP
PAVERVRTLREMTESSRRQS
>Mature_419_residues
TTFALLILFVVETAFAYWLRHINLEHLKRHGMAVPPGFEGAIDEEKLRSSTSYTLDSSRLGLWESLFNNLLLILFLFGGL
LTLLDGFVAGLTPLLMTHGIFFFVAMVWGQAVLDIPFDLYGTFRIEARYGFNTTTPRLWLVDFLKSQAIGTLLLVFLLGA
VFWLIQWSPGRWWVWVWGFMAVFSLFMMLISPYVVEPLFNTFEPVTEEGLEDEIRSLMEKAGLKVGRVMQMDASKRSRHS
NAYFTGIGKVKRIVLYDTLIRQMSHGEIVAVLAHEIGHWKKGHVWKRLLWAELMALAGSWLFFQLLNWPGLPGLLGLPLS
ISLPARMVVVGFLASLALFPFEPLSAWYSRRHEREADRFAADLTGKPHDLASAMVKLSVENLSNLFPHPLYAWFYYSHPP
AVERVRTLREMTESSRRQS

Specific function: Unknown

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Homo sapiens, GI18379366, Length=429, Percent_Identity=29.6037296037296, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17505484, Length=432, Percent_Identity=31.0185185185185, Blast_Score=180, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6322577, Length=422, Percent_Identity=29.6208530805687, Blast_Score=181, Evalue=3e-46,
Organism=Drosophila melanogaster, GI19922414, Length=441, Percent_Identity=27.891156462585, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI78707252, Length=407, Percent_Identity=25.7985257985258, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI78707254, Length=407, Percent_Identity=25.7985257985258, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24654305, Length=293, Percent_Identity=25.938566552901, Blast_Score=103, Evalue=3e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: NA

Molecular weight: Translated: 48064; Mature: 47933

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTFALLILFVVETAFAYWLRHINLEHLKRHGMAVPPGFEGAIDEEKLRSSTSYTLDSSR
CHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEECCHH
LGLWESLFNNLLLILFLFGGLLTLLDGFVAGLTPLLMTHGIFFFVAMVWGQAVLDIPFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YGTFRIEARYGFNTTTPRLWLVDFLKSQAIGTLLLVFLLGAVFWLIQWSPGRWWVWVWGF
EEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MAVFSLFMMLISPYVVEPLFNTFEPVTEEGLEDEIRSLMEKAGLKVGRVMQMDASKRSRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHCC
SNAYFTGIGKVKRIVLYDTLIRQMSHGEIVAVLAHEIGHWKKGHVWKRLLWAELMALAGS
CCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
WLFFQLLNWPGLPGLLGLPLSISLPARMVVVGFLASLALFPFEPLSAWYSRRHEREADRF
HHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AADLTGKPHDLASAMVKLSVENLSNLFPHPLYAWFYYSHPPAVERVRTLREMTESSRRQS
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TTFALLILFVVETAFAYWLRHINLEHLKRHGMAVPPGFEGAIDEEKLRSSTSYTLDSSR
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCHHHHHCCCCCEECCHH
LGLWESLFNNLLLILFLFGGLLTLLDGFVAGLTPLLMTHGIFFFVAMVWGQAVLDIPFDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
YGTFRIEARYGFNTTTPRLWLVDFLKSQAIGTLLLVFLLGAVFWLIQWSPGRWWVWVWGF
EEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
MAVFSLFMMLISPYVVEPLFNTFEPVTEEGLEDEIRSLMEKAGLKVGRVMQMDASKRSRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHCCHHHHCC
SNAYFTGIGKVKRIVLYDTLIRQMSHGEIVAVLAHEIGHWKKGHVWKRLLWAELMALAGS
CCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
WLFFQLLNWPGLPGLLGLPLSISLPARMVVVGFLASLALFPFEPLSAWYSRRHEREADRF
HHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
AADLTGKPHDLASAMVKLSVENLSNLFPHPLYAWFYYSHPPAVERVRTLREMTESSRRQS
HHHCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHEEECCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377; 3145906 [H]