Click here to switch to the map view.

The map label for this gene is degP [H]

Identifier: 118581599

GI number: 118581599

Start: 3514521

End: 3515945

Strand: Reverse

Name: degP [H]

Synonym: Ppro_3198

Alternate gene names: 118581599

Gene position: 3515945-3514521 (Counterclockwise)

Preceding gene: 118581600

Following gene: 118581598

Centisome position: 87.72

GC content: 63.16

Gene sequence:

>1425_bases
ATGAAGCTTTTTCTACGAACCGTACTCCGCATCGTCATCTGCTCCCTGATGGTTTCCGCTCTTGCCGGCTGTTCCGGCGA
TGGTGACGGGCCGCTCTTCTATGAGTCCAAGCGCAAGGGGGGGGAGGCCGAGGCCCCGGTCAAGGATGTGCCGGCAGATA
TGCTGGCCACCCAGAAGGCCTTCAGTCAGGTCGCGAAGAAGGTCACTCCCTGCGTCGTCAACGTCTCCACCGTCGGCAAG
AAGATGGCTGTCCAGCCTTTCTTCCAGATGTCGCCTCTGTTCGAGGACTTCTTCGGCGGCCCCCAGTACCGTCAGAACAA
GAGCCTCGGTTCTGGTTTCATCATCAGCAGGGATGGCTACATCGTCACCAATGAGCATGTGGTGCGCGACGCCGAGAGCA
TCCAGGTGAAGCTCTCCAACGACAAGGTCTACGACGCCAGGGTAGTGGGCAGCGACCAGAAGACCGACATTGCCGTGATC
AAGATCAATGCCGGCGATCTTCCCGTTGCCGTGCTGGGTGATTCCGACAAGCTGGAGGTGGGGCAGTGGGCCGTTGCCAT
CGGCAACCCCTTTGGCCTGGACCGCACCATGACCGTCGGCGTCATCTCCGCCACCGGACGCTCCAACGTGGGTATCGAGA
CCTACGAGAATTTCATCCAGACCGACGCCTCCATTAACCCGGGCAACTCGGGGGGGCCGCTCTTGAACGTCCATGGCGAG
GTGATCGGCATCAATACCGCCATCGTGGCCGCCGGACAGGGGATCGGTTTCGCCATACCGGTGGCCATGGCCAAGCCGAT
CTTCACCCAGTTGATCAACAAGGGGAGTGTCAGCCGGGGGTGGATGGGGGTGACCATCCAGCCGGTCACCGAAGAGTTGG
GGCGGTCCTTCGGATTGCACCAGGCCAAGGGCGCTCTGATCAGCGGGGTCGTGGCGGGCAGCCCAGCCGACAAGGGGGGG
CTGCGCCAGGGGGACATCATCACCGCCTTTAACGGCACCGAGGTCAAGGACCCCGCCCAGCTTCAGCGCCTGGTGGCCGA
GGCGGGCATCGGCAGGCCGGTCAGGGTTACCCTGTTCCGCAACGGCAGGTCGCTGGAGCTGAGCATGACGCTCGTGGCGG
CCGAGTCGGCAGCCCAGGCCAGGAGAGGCGCTGGCGGCGAGCGGCACCAGGTCCAGGCCGATCCGCTGGGGCTGGTGGTG
GAGGATATGGATGGCGCAGGCGTGGTGGTGGCCGATGTGATCAATGGCGGTAGTGCCGCCGATGTGGGCATCCGCCCCGG
AGACCTGATCGTCTCCATCAACCGCAAACGGATTGCCACTACAGCCGAGTACCAGAAGGCGATTCGCCAGGCCCAGGGGG
GGACCCTGATCATTCTTGTCCGTCGGGGCGATTCAAGCATCTATTTCGCCCTGAAGAGCAGATAG

Upstream 100 bases:

>100_bases
GGGTCTGTGCCGGGATTATATCCGTTGACATAACCGTGGAGTTTGGCTAATCTTTCAGCTGGTTTAAGCTGCGCCACTTC
CCCATTCCGGTCCCGAGAAC

Downstream 100 bases:

>100_bases
TGCAAGCAGCCGTGCATCACTAATTTCGCACAAGGAAAGAGCAGCCATGAACTTGATCGACAATCCTGAACAGGCCAAGC
GCCTTGCGAGAGCCATCATC

Product: protease Do

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MKLFLRTVLRIVICSLMVSALAGCSGDGDGPLFYESKRKGGEAEAPVKDVPADMLATQKAFSQVAKKVTPCVVNVSTVGK
KMAVQPFFQMSPLFEDFFGGPQYRQNKSLGSGFIISRDGYIVTNEHVVRDAESIQVKLSNDKVYDARVVGSDQKTDIAVI
KINAGDLPVAVLGDSDKLEVGQWAVAIGNPFGLDRTMTVGVISATGRSNVGIETYENFIQTDASINPGNSGGPLLNVHGE
VIGINTAIVAAGQGIGFAIPVAMAKPIFTQLINKGSVSRGWMGVTIQPVTEELGRSFGLHQAKGALISGVVAGSPADKGG
LRQGDIITAFNGTEVKDPAQLQRLVAEAGIGRPVRVTLFRNGRSLELSMTLVAAESAAQARRGAGGERHQVQADPLGLVV
EDMDGAGVVVADVINGGSAADVGIRPGDLIVSINRKRIATTAEYQKAIRQAQGGTLIILVRRGDSSIYFALKSR

Sequences:

>Translated_474_residues
MKLFLRTVLRIVICSLMVSALAGCSGDGDGPLFYESKRKGGEAEAPVKDVPADMLATQKAFSQVAKKVTPCVVNVSTVGK
KMAVQPFFQMSPLFEDFFGGPQYRQNKSLGSGFIISRDGYIVTNEHVVRDAESIQVKLSNDKVYDARVVGSDQKTDIAVI
KINAGDLPVAVLGDSDKLEVGQWAVAIGNPFGLDRTMTVGVISATGRSNVGIETYENFIQTDASINPGNSGGPLLNVHGE
VIGINTAIVAAGQGIGFAIPVAMAKPIFTQLINKGSVSRGWMGVTIQPVTEELGRSFGLHQAKGALISGVVAGSPADKGG
LRQGDIITAFNGTEVKDPAQLQRLVAEAGIGRPVRVTLFRNGRSLELSMTLVAAESAAQARRGAGGERHQVQADPLGLVV
EDMDGAGVVVADVINGGSAADVGIRPGDLIVSINRKRIATTAEYQKAIRQAQGGTLIILVRRGDSSIYFALKSR
>Mature_474_residues
MKLFLRTVLRIVICSLMVSALAGCSGDGDGPLFYESKRKGGEAEAPVKDVPADMLATQKAFSQVAKKVTPCVVNVSTVGK
KMAVQPFFQMSPLFEDFFGGPQYRQNKSLGSGFIISRDGYIVTNEHVVRDAESIQVKLSNDKVYDARVVGSDQKTDIAVI
KINAGDLPVAVLGDSDKLEVGQWAVAIGNPFGLDRTMTVGVISATGRSNVGIETYENFIQTDASINPGNSGGPLLNVHGE
VIGINTAIVAAGQGIGFAIPVAMAKPIFTQLINKGSVSRGWMGVTIQPVTEELGRSFGLHQAKGALISGVVAGSPADKGG
LRQGDIITAFNGTEVKDPAQLQRLVAEAGIGRPVRVTLFRNGRSLELSMTLVAAESAAQARRGAGGERHQVQADPLGLVV
EDMDGAGVVVADVINGGSAADVGIRPGDLIVSINRKRIATTAEYQKAIRQAQGGTLIILVRRGDSSIYFALKSR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=241, Percent_Identity=42.3236514522822, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI22129776, Length=272, Percent_Identity=38.2352941176471, Blast_Score=156, Evalue=4e-38,
Organism=Homo sapiens, GI24308541, Length=287, Percent_Identity=35.5400696864112, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI7019477, Length=246, Percent_Identity=39.0243902439024, Blast_Score=136, Evalue=4e-32,
Organism=Escherichia coli, GI1789629, Length=429, Percent_Identity=38.9277389277389, Blast_Score=274, Evalue=8e-75,
Organism=Escherichia coli, GI1786356, Length=444, Percent_Identity=36.2612612612613, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1789630, Length=322, Percent_Identity=35.0931677018634, Blast_Score=179, Evalue=3e-46,
Organism=Drosophila melanogaster, GI24646839, Length=298, Percent_Identity=35.5704697986577, Blast_Score=168, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 49886; Mature: 49886

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFLRTVLRIVICSLMVSALAGCSGDGDGPLFYESKRKGGEAEAPVKDVPADMLATQKA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHCCHHHHHHHHH
FSQVAKKVTPCVVNVSTVGKKMAVQPFFQMSPLFEDFFGGPQYRQNKSLGSGFIISRDGY
HHHHHHHCCCEEEEHHHCCCHHCCCCHHHHCHHHHHHCCCCCCCCCCCCCCCEEEECCCE
IVTNEHVVRDAESIQVKLSNDKVYDARVVGSDQKTDIAVIKINAGDLPVAVLGDSDKLEV
EEECCHHCCCCCEEEEEECCCEEEEEEEECCCCCCEEEEEEEECCCCCEEEECCCCCEEE
GQWAVAIGNPFGLDRTMTVGVISATGRSNVGIETYENFIQTDASINPGNSGGPLLNVHGE
CEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCE
VIGINTAIVAAGQGIGFAIPVAMAKPIFTQLINKGSVSRGWMGVTIQPVTEELGRSFGLH
EEEEEEEEEECCCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHCCCC
QAKGALISGVVAGSPADKGGLRQGDIITAFNGTEVKDPAQLQRLVAEAGIGRPVRVTLFR
HHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
NGRSLELSMTLVAAESAAQARRGAGGERHQVQADPLGLVVEDMDGAGVVVADVINGGSAA
CCCEEEEEEEEEECHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCEEEEEEECCCCCC
DVGIRPGDLIVSINRKRIATTAEYQKAIRQAQGGTLIILVRRGDSSIYFALKSR
CCCCCCCCEEEEECCCCEEHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECC
>Mature Secondary Structure
MKLFLRTVLRIVICSLMVSALAGCSGDGDGPLFYESKRKGGEAEAPVKDVPADMLATQKA
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCHHHCCHHHHHHHHH
FSQVAKKVTPCVVNVSTVGKKMAVQPFFQMSPLFEDFFGGPQYRQNKSLGSGFIISRDGY
HHHHHHHCCCEEEEHHHCCCHHCCCCHHHHCHHHHHHCCCCCCCCCCCCCCCEEEECCCE
IVTNEHVVRDAESIQVKLSNDKVYDARVVGSDQKTDIAVIKINAGDLPVAVLGDSDKLEV
EEECCHHCCCCCEEEEEECCCEEEEEEEECCCCCCEEEEEEEECCCCCEEEECCCCCEEE
GQWAVAIGNPFGLDRTMTVGVISATGRSNVGIETYENFIQTDASINPGNSGGPLLNVHGE
CEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCE
VIGINTAIVAAGQGIGFAIPVAMAKPIFTQLINKGSVSRGWMGVTIQPVTEELGRSFGLH
EEEEEEEEEECCCCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHHHHCCCC
QAKGALISGVVAGSPADKGGLRQGDIITAFNGTEVKDPAQLQRLVAEAGIGRPVRVTLFR
HHCCCEEEEEEECCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCCEEEEEEE
NGRSLELSMTLVAAESAAQARRGAGGERHQVQADPLGLVVEDMDGAGVVVADVINGGSAA
CCCEEEEEEEEEECHHHHHHHHCCCCCCCEEECCCCEEEEECCCCCCEEEEEEECCCCCC
DVGIRPGDLIVSINRKRIATTAEYQKAIRQAQGGTLIILVRRGDSSIYFALKSR
CCCCCCCCEEEEECCCCEEHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10684935 [H]