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The map label for this gene is argB

Identifier: 118581575

GI number: 118581575

Start: 3487579

End: 3488457

Strand: Reverse

Name: argB

Synonym: Ppro_3174

Alternate gene names: 118581575

Gene position: 3488457-3487579 (Counterclockwise)

Preceding gene: 118581576

Following gene: 118581574

Centisome position: 87.04

GC content: 60.86

Gene sequence:

>879_bases
ATGGAAAAACTGATTGAGAAGGCAAACAACCTGATGGAGGCGCTCCCCTATATCAGGCGCTTTGCCGGAAAAACCTTTGT
CATCAAGTACGGCGGCCACGCCATGTCCGACGAGAAGCTGAAGGAGTCTTTTGCCCTGGACGTGATCATGCTCAGGTCGC
TGGGGATCAACGCGGTCATCGTCCACGGCGGTGGGCCGCAGATCAACCAGACCCTCAAGCGCTATGGTATCGTCTCCCAG
TTCGTCAAAGGGATGCGGGTCACCGACAGCGAGACCATGGCGGTGGTGGAGATGGTGCTGGTGGGGCAGGTCAACAAGGA
GGTCGTGGGCTACCTGAACCAGCACGGTGGCAGGGCCGTCGGTCTGTCCGGCAAGGACGGTACGCTGCTCCTCTCCAAAA
AGCTGCTCCAGGATGTGGTCGGTGATGACGGCACGACGGAGCAGGTGGACATGGGCTATGTGGGGGACGTGGTCAAGGTC
AACACCGACCTGCTCAAGGCACTGGAAAACGGCAACTATCTCCCGGTCATCGCGCCGGTGGGGGTGGGCCCCCAGGGGGA
GAGCTACAACATCAACGCCGACCTGGTGGCTGGCCGGGTGGCGGCGGCGCTCAATGCCGAGAAACTGATCCTTTTGACCG
ACATCGAAGGGGTCAAGGACAAGGCCGGGCAGCTCCTTTCCAGCATTGCCGTGGCGGACATGCATCGCCTGATCCGCGAG
GAGGCCATCACCGGTGGCATGATCCCCAAGGTGGTCTGTTGCGCCGACGCCCTGGAAGAAGGGGTGAAAAAGGCCCATAT
CATCGACGGCCGGGTGGAACACGCGGTGCTGCTGGAGATCTTCACCGACGTGGGCATCGGGACCGAGATACAAAAGTGA

Upstream 100 bases:

>100_bases
TGTAGCGAAATAATCCTGGAGTTACAGAAAGAGCCCGTCCGCACGAACGCAGTCGGTTGTCACCTGACGAATTTCAAACG
TTGCAGCAGAGGACTACCCC

Downstream 100 bases:

>100_bases
CAGCGAGGTAACCATGAATTCTGAACAGTGGATCGAAAAATCGGACAGGTACATCATGAAGAACTACGGACGTTTCCCGC
TGGTGCCGCTGCGCGGCGAG

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MEKLIEKANNLMEALPYIRRFAGKTFVIKYGGHAMSDEKLKESFALDVIMLRSLGINAVIVHGGGPQINQTLKRYGIVSQ
FVKGMRVTDSETMAVVEMVLVGQVNKEVVGYLNQHGGRAVGLSGKDGTLLLSKKLLQDVVGDDGTTEQVDMGYVGDVVKV
NTDLLKALENGNYLPVIAPVGVGPQGESYNINADLVAGRVAAALNAEKLILLTDIEGVKDKAGQLLSSIAVADMHRLIRE
EAITGGMIPKVVCCADALEEGVKKAHIIDGRVEHAVLLEIFTDVGIGTEIQK

Sequences:

>Translated_292_residues
MEKLIEKANNLMEALPYIRRFAGKTFVIKYGGHAMSDEKLKESFALDVIMLRSLGINAVIVHGGGPQINQTLKRYGIVSQ
FVKGMRVTDSETMAVVEMVLVGQVNKEVVGYLNQHGGRAVGLSGKDGTLLLSKKLLQDVVGDDGTTEQVDMGYVGDVVKV
NTDLLKALENGNYLPVIAPVGVGPQGESYNINADLVAGRVAAALNAEKLILLTDIEGVKDKAGQLLSSIAVADMHRLIRE
EAITGGMIPKVVCCADALEEGVKKAHIIDGRVEHAVLLEIFTDVGIGTEIQK
>Mature_292_residues
MEKLIEKANNLMEALPYIRRFAGKTFVIKYGGHAMSDEKLKESFALDVIMLRSLGINAVIVHGGGPQINQTLKRYGIVSQ
FVKGMRVTDSETMAVVEMVLVGQVNKEVVGYLNQHGGRAVGLSGKDGTLLLSKKLLQDVVGDDGTTEQVDMGYVGDVVKV
NTDLLKALENGNYLPVIAPVGVGPQGESYNINADLVAGRVAAALNAEKLILLTDIEGVKDKAGQLLSSIAVADMHRLIRE
EAITGGMIPKVVCCADALEEGVKKAHIIDGRVEHAVLLEIFTDVGIGTEIQK

Specific function: Arginine biosynthesis; first step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI1789181, Length=296, Percent_Identity=27.027027027027, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693208, Length=269, Percent_Identity=32.3420074349442, Blast_Score=95, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320913, Length=283, Percent_Identity=27.208480565371, Blast_Score=81, Evalue=2e-16,

Paralogues:

None

Copy number: 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ARGB_PELPD (A1ATU7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902825.1
- ProteinModelPortal:   A1ATU7
- SMR:   A1ATU7
- STRING:   A1ATU7
- GeneID:   4573276
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3174
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   A1ATU7
- ProtClustDB:   PRK00942
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- InterPro:   IPR001057
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- PRINTS:   PR00474
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 31290; Mature: 31290

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: BINDING 86-86 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLIEKANNLMEALPYIRRFAGKTFVIKYGGHAMSDEKLKESFALDVIMLRSLGINAVI
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
VHGGGPQINQTLKRYGIVSQFVKGMRVTDSETMAVVEMVLVGQVNKEVVGYLNQHGGRAV
EECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GLSGKDGTLLLSKKLLQDVVGDDGTTEQVDMGYVGDVVKVNTDLLKALENGNYLPVIAPV
ECCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCEEECHHHHHHHHCCCEEEEEEEC
GVGPQGESYNINADLVAGRVAAALNAEKLILLTDIEGVKDKAGQLLSSIAVADMHRLIRE
CCCCCCCCEECCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EAITGGMIPKVVCCADALEEGVKKAHIIDGRVEHAVLLEIFTDVGIGTEIQK
HHHCCCCHHHHHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MEKLIEKANNLMEALPYIRRFAGKTFVIKYGGHAMSDEKLKESFALDVIMLRSLGINAVI
CHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEE
VHGGGPQINQTLKRYGIVSQFVKGMRVTDSETMAVVEMVLVGQVNKEVVGYLNQHGGRAV
EECCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEE
GLSGKDGTLLLSKKLLQDVVGDDGTTEQVDMGYVGDVVKVNTDLLKALENGNYLPVIAPV
ECCCCCCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCEEECHHHHHHHHCCCEEEEEEEC
GVGPQGESYNINADLVAGRVAAALNAEKLILLTDIEGVKDKAGQLLSSIAVADMHRLIRE
CCCCCCCCEECCHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
EAITGGMIPKVVCCADALEEGVKKAHIIDGRVEHAVLLEIFTDVGIGTEIQK
HHHCCCCHHHHHHHHHHHHHHHHHEEHCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA