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The map label for this gene is yycG [H]

Identifier: 118581576

GI number: 118581576

Start: 3488781

End: 3489893

Strand: Reverse

Name: yycG [H]

Synonym: Ppro_3175

Alternate gene names: 118581576

Gene position: 3489893-3488781 (Counterclockwise)

Preceding gene: 118581577

Following gene: 118581575

Centisome position: 87.07

GC content: 60.29

Gene sequence:

>1113_bases
GTGAAACGACGCCATCGGAACGACAGAGGAGATCATCGGCAAAAGAGGACGATTCTGGTCGTGGATGACGACAGCGCCAT
CCTCGCCCTCTGTGGCCGGGTGCTGAGAGGGTATCGGGTGCTCCAGGCGCGGAACTGTACCGAAGCCCTGAAAATGTTCG
AGAACGAAGCGGTTGACCTCGTCCTGACCGATGCGAAGATTCCGGGTGAGTGCGGCATCGACCTGCTCAGGCGCATCAAG
GGACTTCAGCCCGATGCGCTGGTGATCATCATGAGCGCTTGCGCCGACCAGGAAACCGTGCTCAGGTCCCTGAGGGAAGG
GGTGGACGACTTCATCTGCAAGCAGTTCATCCAGCTGCAGCTGCGGGAATCCATTGAAAAGGTGCTTTTCAGGAAGATCC
TGCGGGCGGAGGCGGCTGATAAGAAGAGGTTGGAGTGCCTGAGAAGCGGTTTCCTCTCCCTCATCTCCCACAAGCTGCGC
ACGCCGATCACCAATATCTCGCTGATTCTGGAATACCTCGATCAGAGCGTCTGCGGCTCGGGCGCGAACGGCTGCCGCCA
GGCCATTGCCACAGCCGGTGAGGAAGCCTCCTATCTGGGGCGGTTGGTGGATGAGCTGTTGCTGTTCAGCCAGGTAATGG
GAGGAGAAGAGGTGCGGCCTGAGAAGGTCGACCTCGTCTCCCTGGTGGCCAACGCGCTGCAGGAGTCACCCGAGTCCCAG
GCCAAGCCGGGTGTGGAGACGTTTTTTGAACCGAGCACCCTAGAATCCTTGAACCTCGACCTCCGCAAGATCGCCTTCGC
CCTCCAGCAGGTCATCGACAACGCCTACAAGTTTTCACCAGAGCCGGGCCGGGTGTCCGTCGCCCTCTGTCAGGGTAACG
GCGAGATCAAGATCGTTGTCGTCGATTCAGGCTCCGGCATCCCCCGTGAGGAGCAGGAAAAGGTGTTCGACAAGTTCTAC
CAGGTGGATCCGGACGGCACCGGACAGGTGCGCGGCCTGGGGTTGGGACTGTTCTACGCCAGGGAATACGTCCTTCTGCA
CGGAGGGGCAATCACCCTGGAGAGCGAACCCGGGTCGGGAACGACCGTCACCATCGTGCTTCCCCTGCAATAA

Upstream 100 bases:

>100_bases
GGCGGTTCCCGTCCGGAAAACCTGGCCGAGGCCCTGGCTGCCGCGAGACAGGTGCTGGCTGAGCAGTAGCAGCGCCCATG
GGTGTCTTGTGGGAGGGTGC

Downstream 100 bases:

>100_bases
GTTTTTGAGGTTTTGTTTATTTTGCGTTAGACTGCCACCTTTGCGGATGGCTTTTTTTTTCGGCGCCGGGAGTCAGGCAA
CCCCGATACAGGTTTGCTGT

Product: response regulator receiver sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MKRRHRNDRGDHRQKRTILVVDDDSAILALCGRVLRGYRVLQARNCTEALKMFENEAVDLVLTDAKIPGECGIDLLRRIK
GLQPDALVIIMSACADQETVLRSLREGVDDFICKQFIQLQLRESIEKVLFRKILRAEAADKKRLECLRSGFLSLISHKLR
TPITNISLILEYLDQSVCGSGANGCRQAIATAGEEASYLGRLVDELLLFSQVMGGEEVRPEKVDLVSLVANALQESPESQ
AKPGVETFFEPSTLESLNLDLRKIAFALQQVIDNAYKFSPEPGRVSVALCQGNGEIKIVVVDSGSGIPREEQEKVFDKFY
QVDPDGTGQVRGLGLGLFYAREYVLLHGGAITLESEPGSGTTVTIVLPLQ

Sequences:

>Translated_370_residues
MKRRHRNDRGDHRQKRTILVVDDDSAILALCGRVLRGYRVLQARNCTEALKMFENEAVDLVLTDAKIPGECGIDLLRRIK
GLQPDALVIIMSACADQETVLRSLREGVDDFICKQFIQLQLRESIEKVLFRKILRAEAADKKRLECLRSGFLSLISHKLR
TPITNISLILEYLDQSVCGSGANGCRQAIATAGEEASYLGRLVDELLLFSQVMGGEEVRPEKVDLVSLVANALQESPESQ
AKPGVETFFEPSTLESLNLDLRKIAFALQQVIDNAYKFSPEPGRVSVALCQGNGEIKIVVVDSGSGIPREEQEKVFDKFY
QVDPDGTGQVRGLGLGLFYAREYVLLHGGAITLESEPGSGTTVTIVLPLQ
>Mature_370_residues
MKRRHRNDRGDHRQKRTILVVDDDSAILALCGRVLRGYRVLQARNCTEALKMFENEAVDLVLTDAKIPGECGIDLLRRIK
GLQPDALVIIMSACADQETVLRSLREGVDDFICKQFIQLQLRESIEKVLFRKILRAEAADKKRLECLRSGFLSLISHKLR
TPITNISLILEYLDQSVCGSGANGCRQAIATAGEEASYLGRLVDELLLFSQVMGGEEVRPEKVDLVSLVANALQESPESQ
AKPGVETFFEPSTLESLNLDLRKIAFALQQVIDNAYKFSPEPGRVSVALCQGNGEIKIVVVDSGSGIPREEQEKVFDKFY
QVDPDGTGQVRGLGLGLFYAREYVLLHGGAITLESEPGSGTTVTIVLPLQ

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=32.0512820512821, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI145693157, Length=231, Percent_Identity=29.4372294372294, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=29.1497975708502, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=29.0748898678414, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082128, Length=235, Percent_Identity=26.8085106382979, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI48994928, Length=228, Percent_Identity=29.8245614035088, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=27.9475982532751, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=27.6150627615063, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786783, Length=230, Percent_Identity=28.695652173913, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=24.6808510638298, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1789149, Length=292, Percent_Identity=24.6575342465753, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788549, Length=242, Percent_Identity=24.7933884297521, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=35.9649122807018, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40872; Mature: 40872

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRRHRNDRGDHRQKRTILVVDDDSAILALCGRVLRGYRVLQARNCTEALKMFENEAVDL
CCCCCCCCCCCCHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEE
VLTDAKIPGECGIDLLRRIKGLQPDALVIIMSACADQETVLRSLREGVDDFICKQFIQLQ
EEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LRESIEKVLFRKILRAEAADKKRLECLRSGFLSLISHKLRTPITNISLILEYLDQSVCGS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
GANGCRQAIATAGEEASYLGRLVDELLLFSQVMGGEEVRPEKVDLVSLVANALQESPESQ
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHH
AKPGVETFFEPSTLESLNLDLRKIAFALQQVIDNAYKFSPEPGRVSVALCQGNGEIKIVV
CCCCHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEE
VDSGSGIPREEQEKVFDKFYQVDPDGTGQVRGLGLGLFYAREYVLLHGGAITLESEPGSG
EECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHEEECCEEEEECCCCCC
TTVTIVLPLQ
CEEEEEEECC
>Mature Secondary Structure
MKRRHRNDRGDHRQKRTILVVDDDSAILALCGRVLRGYRVLQARNCTEALKMFENEAVDL
CCCCCCCCCCCCHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEE
VLTDAKIPGECGIDLLRRIKGLQPDALVIIMSACADQETVLRSLREGVDDFICKQFIQLQ
EEECCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
LRESIEKVLFRKILRAEAADKKRLECLRSGFLSLISHKLRTPITNISLILEYLDQSVCGS
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
GANGCRQAIATAGEEASYLGRLVDELLLFSQVMGGEEVRPEKVDLVSLVANALQESPESQ
CCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCHHH
AKPGVETFFEPSTLESLNLDLRKIAFALQQVIDNAYKFSPEPGRVSVALCQGNGEIKIVV
CCCCHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEEE
VDSGSGIPREEQEKVFDKFYQVDPDGTGQVRGLGLGLFYAREYVLLHGGAITLESEPGSG
EECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHEEECCEEEEECCCCCC
TTVTIVLPLQ
CEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]