Click here to switch to the map view.

The map label for this gene is argD [H]

Identifier: 118581574

GI number: 118581574

Start: 3486369

End: 3487565

Strand: Reverse

Name: argD [H]

Synonym: Ppro_3173

Alternate gene names: 118581574

Gene position: 3487565-3486369 (Counterclockwise)

Preceding gene: 118581575

Following gene: 118581573

Centisome position: 87.02

GC content: 63.41

Gene sequence:

>1197_bases
ATGAATTCTGAACAGTGGATCGAAAAATCGGACAGGTACATCATGAAGAACTACGGACGTTTCCCGCTGGTGCCGCTGCG
CGGCGAGGGATGCCGTCTGTGGGATGCCGACGGCAGGGAATATCTGGATTTCCTGGGCGGCATCGCGGTCAACAACCTGG
GGCACTGCCCCCCCAAGGTTGTCGAGGCACTGAGACGCCAGGCCGGCGAGATGATCCACTGCTCCAACCTGTACCAGATA
CCGCGCCAGATCGAACTGGCTGAACTGCTCTGCCAGAACTCCTTTGCCGACAAGGCCTTCTTCTGCAACAGCGGGGCCGA
GGCCAACGAGGCGGCCATCAAGCTGGCCCGCAAGTACAGCCGTGACAATTTTGGACCGGAGCGGTTCGCCATCATCACCG
CCACCGACTCATTCCACGGCCGCACCATGGCCACCGTCTCCGCCACCGGCCAGGAGAAGGTGCAGCGCTTCTTCGATCCG
CTGCTGCACGGCTTCAGCCACGTCCCCTTCAACGACCCGGCGGCGCTGGAGGCGGCGATTACGCCGGCCACCTGCGCCAT
CATGCTGGAGCCGATCCAGGGGGAGAGCGGGGTCAACATCCCCTCGTCGGACTATTTCCGGGAGGTGCGCCGCATCTGCG
ACGAGTACAACCTGCTGCTCATCTTCGACGAGGTCCAGGTGGGCATGGGACGCACCGGCAGGCTCTTCGCCTACGAAAAC
TTCGACTGCACCCCGGACATCATGACCCTGGCCAAGGCCCTGGCAGGGGGAGCGCCCATCGGCGCCATGCTGGCCAAGGA
CGAGATCGCCGCCTCCTTCACCCCCGGCACCCACGGCTCCACCTTCGGGGGCAATCCGCTGGTCTGCGCAGCCGCCGTGG
CGACCCTGCGCGTCATGCTGGACGAGGATATCCTTGCCCGCACCAGGGAAACCGGCGCCTATCTCATGGCAGAGCTGGAA
AAACTGGCGCAGACGTATCCCTTTGCCGGCCCGGTGCGCGGCATCGGCCTGATGGTCGGCATGCCCCTCTCCATTCCGGC
GGGGGACATCGTCAGGAAGGGGCATGAACGGGGCGTGCTGCTCAATGCGGTGCACGACACGGTACTGCGTTTCGTGCCGC
CGCTGATCGTAACCAAACAGGAAGTTGATCAGATGATTTTCATTCTCGACGGCATCTTGGCCGAGGTCGAGGCATAA

Upstream 100 bases:

>100_bases
GCCCATATCATCGACGGCCGGGTGGAACACGCGGTGCTGCTGGAGATCTTCACCGACGTGGGCATCGGGACCGAGATACA
AAAGTGACAGCGAGGTAACC

Downstream 100 bases:

>100_bases
CAAGGGGGTGCACTATGGCGCGACACTTTCTCTCGCTGCACGACTACACCAAGGAAGAACTGGACCGGCTGCTGGCGCTG
GCCATCGAGCTTAAGCAGGA

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNSEQWIEKSDRYIMKNYGRFPLVPLRGEGCRLWDADGREYLDFLGGIAVNNLGHCPPKVVEALRRQAGEMIHCSNLYQI
PRQIELAELLCQNSFADKAFFCNSGAEANEAAIKLARKYSRDNFGPERFAIITATDSFHGRTMATVSATGQEKVQRFFDP
LLHGFSHVPFNDPAALEAAITPATCAIMLEPIQGESGVNIPSSDYFREVRRICDEYNLLLIFDEVQVGMGRTGRLFAYEN
FDCTPDIMTLAKALAGGAPIGAMLAKDEIAASFTPGTHGSTFGGNPLVCAAAVATLRVMLDEDILARTRETGAYLMAELE
KLAQTYPFAGPVRGIGLMVGMPLSIPAGDIVRKGHERGVLLNAVHDTVLRFVPPLIVTKQEVDQMIFILDGILAEVEA

Sequences:

>Translated_398_residues
MNSEQWIEKSDRYIMKNYGRFPLVPLRGEGCRLWDADGREYLDFLGGIAVNNLGHCPPKVVEALRRQAGEMIHCSNLYQI
PRQIELAELLCQNSFADKAFFCNSGAEANEAAIKLARKYSRDNFGPERFAIITATDSFHGRTMATVSATGQEKVQRFFDP
LLHGFSHVPFNDPAALEAAITPATCAIMLEPIQGESGVNIPSSDYFREVRRICDEYNLLLIFDEVQVGMGRTGRLFAYEN
FDCTPDIMTLAKALAGGAPIGAMLAKDEIAASFTPGTHGSTFGGNPLVCAAAVATLRVMLDEDILARTRETGAYLMAELE
KLAQTYPFAGPVRGIGLMVGMPLSIPAGDIVRKGHERGVLLNAVHDTVLRFVPPLIVTKQEVDQMIFILDGILAEVEA
>Mature_398_residues
MNSEQWIEKSDRYIMKNYGRFPLVPLRGEGCRLWDADGREYLDFLGGIAVNNLGHCPPKVVEALRRQAGEMIHCSNLYQI
PRQIELAELLCQNSFADKAFFCNSGAEANEAAIKLARKYSRDNFGPERFAIITATDSFHGRTMATVSATGQEKVQRFFDP
LLHGFSHVPFNDPAALEAAITPATCAIMLEPIQGESGVNIPSSDYFREVRRICDEYNLLLIFDEVQVGMGRTGRLFAYEN
FDCTPDIMTLAKALAGGAPIGAMLAKDEIAASFTPGTHGSTFGGNPLVCAAAVATLRVMLDEDILARTRETGAYLMAELE
KLAQTYPFAGPVRGIGLMVGMPLSIPAGDIVRKGHERGVLLNAVHDTVLRFVPPLIVTKQEVDQMIFILDGILAEVEA

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=397, Percent_Identity=36.272040302267, Blast_Score=253, Evalue=3e-67,
Organism=Homo sapiens, GI284507298, Length=296, Percent_Identity=37.8378378378378, Blast_Score=197, Evalue=1e-50,
Organism=Homo sapiens, GI13994255, Length=442, Percent_Identity=29.185520361991, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI37574042, Length=420, Percent_Identity=29.0476190476191, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI226442705, Length=420, Percent_Identity=28.0952380952381, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI226442709, Length=389, Percent_Identity=29.305912596401, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI24119277, Length=417, Percent_Identity=25.6594724220624, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI188536080, Length=425, Percent_Identity=24.4705882352941, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679950, Length=425, Percent_Identity=24.4705882352941, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI38679946, Length=425, Percent_Identity=24.4705882352941, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI1788044, Length=379, Percent_Identity=43.7994722955145, Blast_Score=328, Evalue=3e-91,
Organism=Escherichia coli, GI1789759, Length=378, Percent_Identity=42.8571428571429, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI145693181, Length=374, Percent_Identity=37.9679144385027, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1789016, Length=436, Percent_Identity=33.7155963302752, Blast_Score=230, Evalue=1e-61,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=33.8308457711443, Blast_Score=188, Evalue=7e-49,
Organism=Escherichia coli, GI1786991, Length=407, Percent_Identity=28.009828009828, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1786349, Length=293, Percent_Identity=27.6450511945392, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI25144271, Length=395, Percent_Identity=35.6962025316456, Blast_Score=263, Evalue=8e-71,
Organism=Caenorhabditis elegans, GI25144274, Length=263, Percent_Identity=38.0228136882129, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=30.184331797235, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI71992977, Length=431, Percent_Identity=27.8422273781903, Blast_Score=154, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI71981843, Length=174, Percent_Identity=31.6091954022989, Blast_Score=105, Evalue=6e-23,
Organism=Caenorhabditis elegans, GI17541228, Length=435, Percent_Identity=24.8275862068966, Blast_Score=91, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6323470, Length=405, Percent_Identity=34.5679012345679, Blast_Score=252, Evalue=8e-68,
Organism=Saccharomyces cerevisiae, GI6324432, Length=373, Percent_Identity=34.8525469168901, Blast_Score=236, Evalue=4e-63,
Organism=Saccharomyces cerevisiae, GI6321456, Length=379, Percent_Identity=26.9129287598945, Blast_Score=99, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6324386, Length=447, Percent_Identity=23.2662192393736, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI21357415, Length=393, Percent_Identity=36.3867684478371, Blast_Score=257, Evalue=9e-69,
Organism=Drosophila melanogaster, GI28574759, Length=433, Percent_Identity=30.9468822170901, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI161085790, Length=417, Percent_Identity=31.4148681055156, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI21356575, Length=414, Percent_Identity=27.7777777777778, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI281366494, Length=422, Percent_Identity=22.7488151658768, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24667139, Length=422, Percent_Identity=22.7488151658768, Blast_Score=92, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24667143, Length=422, Percent_Identity=22.7488151658768, Blast_Score=92, Evalue=8e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43621; Mature: 43621

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS00599 AA_TRANSFER_CLASS_2 ; PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSEQWIEKSDRYIMKNYGRFPLVPLRGEGCRLWDADGREYLDFLGGIAVNNLGHCPPKV
CCCHHHHHHHCCHHHHCCCCCCEEEECCCCCEEECCCCHHHHHHHCCHHHCCCCCCCHHH
VEALRRQAGEMIHCSNLYQIPRQIELAELLCQNSFADKAFFCNSGAEANEAAIKLARKYS
HHHHHHHHCCEEEHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHH
RDNFGPERFAIITATDSFHGRTMATVSATGQEKVQRFFDPLLHGFSHVPFNDPAALEAAI
CCCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
TPATCAIMLEPIQGESGVNIPSSDYFREVRRICDEYNLLLIFDEVQVGMGRTGRLFAYEN
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCEEEEECC
FDCTPDIMTLAKALAGGAPIGAMLAKDEIAASFTPGTHGSTFGGNPLVCAAAVATLRVML
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
DEDILARTRETGAYLMAELEKLAQTYPFAGPVRGIGLMVGMPLSIPAGDIVRKGHERGVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCCHHHHHCCCCCCEE
LNAVHDTVLRFVPPLIVTKQEVDQMIFILDGILAEVEA
HHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSEQWIEKSDRYIMKNYGRFPLVPLRGEGCRLWDADGREYLDFLGGIAVNNLGHCPPKV
CCCHHHHHHHCCHHHHCCCCCCEEEECCCCCEEECCCCHHHHHHHCCHHHCCCCCCCHHH
VEALRRQAGEMIHCSNLYQIPRQIELAELLCQNSFADKAFFCNSGAEANEAAIKLARKYS
HHHHHHHHCCEEEHHHHHHCHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHH
RDNFGPERFAIITATDSFHGRTMATVSATGQEKVQRFFDPLLHGFSHVPFNDPAALEAAI
CCCCCCCEEEEEEECCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHC
TPATCAIMLEPIQGESGVNIPSSDYFREVRRICDEYNLLLIFDEVQVGMGRTGRLFAYEN
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHCCCCCCEEEEECC
FDCTPDIMTLAKALAGGAPIGAMLAKDEIAASFTPGTHGSTFGGNPLVCAAAVATLRVML
CCCCHHHHHHHHHHHCCCCHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHHHHHHHHHHH
DEDILARTRETGAYLMAELEKLAQTYPFAGPVRGIGLMVGMPLSIPAGDIVRKGHERGVL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHEECCCCCCCCHHHHHCCCCCCEE
LNAVHDTVLRFVPPLIVTKQEVDQMIFILDGILAEVEA
HHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]