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The map label for this gene is dapB

Identifier: 118581465

GI number: 118581465

Start: 3351155

End: 3351958

Strand: Reverse

Name: dapB

Synonym: Ppro_3062

Alternate gene names: 118581465

Gene position: 3351958-3351155 (Counterclockwise)

Preceding gene: 118581466

Following gene: 118581464

Centisome position: 83.63

GC content: 63.31

Gene sequence:

>804_bases
ATGATCAAGATAGCTGTCTGCGGAGCTGCCGGCCGCATGGGACAACGCCTCATCAATTCCGTGCAGGAGGCCGAGGGTGT
ATGTCTCTCCGGCGTACTGGAACGGCCCGCCCATCCGCTGGTGGGACAGGATGCCGGGCTGGTTGCCGGATGCGGGGCAC
TGGGTGTCAGCATCTCCGACGATCTCAACGCCGTCATTGCCGGTTGCGATGTCCTGATCGATTTCACCGCCCCCAAGGTA
TCCCTCAAGAACCTGGAGGCCTGCGGGTTGCAGCGGAAGTCCATCGTCATCGGCTCCACCGGCTTTACCCCCGAGGAGCG
CCAGCTGGCAATGGAGCTGACCAGAAACATCTCGGCCATACTGGCGCCCAATATGTCGGTGGGGGTCAATGTCTGCTTCA
AGATCCTCAAGGACATCGCGGCGACCCTTGGCGACGACTTCGACGTGGAGATTGTCGAGTCCCATCACCGCATGAAGGTG
GACGCTCCTTCCGGCACCGCGGTGCGCATGGGGCAGGTGGTTGCCGAGGCCCTGGGGCGTGACTACGACCGGGTGGCGAA
CTTCCACCGGGAGGGAATCACCGGCAGCCGCACAAAGGATGAGATCGGCATGCAGACCATCCGCGGCGGCGACATCGTCG
GCGAGCACACGGTCTACTTCATCGGCATGGGTGAGCGCATCGAGCTCTCCCACCGCGCCATGAACCGGGACATGTTCTCG
CGGGGAGCGGTCCGCGCCGCCACGTGGGTGGTGGGTCAGGCGCCCGGTCTCTACGACATGCAGGATGTGCTTGGTTTGAA
ATAG

Upstream 100 bases:

>100_bases
CTGTGCGCTGTCATGAAATCCTACGGCCTGATCTAGGATGTGAGGGACACTAATTTCCCGTGACGCGACGTGAACGAATG
ATTCCAGAGAGGGTAATGCC

Downstream 100 bases:

>100_bases
CTTTTCCGTTTGCAGGCGCTGTGCAATTTCATATCGAACAAAGGATATTCGCGTATGGCAAAGATAAATGACAACTACCT
GAAGCTGAAAGCCGGGTACC

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MIKIAVCGAAGRMGQRLINSVQEAEGVCLSGVLERPAHPLVGQDAGLVAGCGALGVSISDDLNAVIAGCDVLIDFTAPKV
SLKNLEACGLQRKSIVIGSTGFTPEERQLAMELTRNISAILAPNMSVGVNVCFKILKDIAATLGDDFDVEIVESHHRMKV
DAPSGTAVRMGQVVAEALGRDYDRVANFHREGITGSRTKDEIGMQTIRGGDIVGEHTVYFIGMGERIELSHRAMNRDMFS
RGAVRAATWVVGQAPGLYDMQDVLGLK

Sequences:

>Translated_267_residues
MIKIAVCGAAGRMGQRLINSVQEAEGVCLSGVLERPAHPLVGQDAGLVAGCGALGVSISDDLNAVIAGCDVLIDFTAPKV
SLKNLEACGLQRKSIVIGSTGFTPEERQLAMELTRNISAILAPNMSVGVNVCFKILKDIAATLGDDFDVEIVESHHRMKV
DAPSGTAVRMGQVVAEALGRDYDRVANFHREGITGSRTKDEIGMQTIRGGDIVGEHTVYFIGMGERIELSHRAMNRDMFS
RGAVRAATWVVGQAPGLYDMQDVLGLK
>Mature_267_residues
MIKIAVCGAAGRMGQRLINSVQEAEGVCLSGVLERPAHPLVGQDAGLVAGCGALGVSISDDLNAVIAGCDVLIDFTAPKV
SLKNLEACGLQRKSIVIGSTGFTPEERQLAMELTRNISAILAPNMSVGVNVCFKILKDIAATLGDDFDVEIVESHHRMKV
DAPSGTAVRMGQVVAEALGRDYDRVANFHREGITGSRTKDEIGMQTIRGGDIVGEHTVYFIGMGERIELSHRAMNRDMFS
RGAVRAATWVVGQAPGLYDMQDVLGLK

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=266, Percent_Identity=47.7443609022556, Blast_Score=247, Evalue=5e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_PELPD (A1ATI7)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902715.1
- ProteinModelPortal:   A1ATI7
- SMR:   A1ATI7
- STRING:   A1ATI7
- GeneID:   4574107
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_3062
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- PhylomeDB:   A1ATI7
- ProtClustDB:   PRK00048
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28435; Mature: 28435

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKIAVCGAAGRMGQRLINSVQEAEGVCLSGVLERPAHPLVGQDAGLVAGCGALGVSISD
CEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEEHHHHCCCCCC
DLNAVIAGCDVLIDFTAPKVSLKNLEACGLQRKSIVIGSTGFTPEERQLAMELTRNISAI
CHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCHHEE
LAPNMSVGVNVCFKILKDIAATLGDDFDVEIVESHHRMKVDAPSGTAVRMGQVVAEALGR
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHCC
DYDRVANFHREGITGSRTKDEIGMQTIRGGDIVGEHTVYFIGMGERIELSHRAMNRDMFS
CHHHHHHHHHCCCCCCCCHHHHCHHHCCCCCEECCCEEEEEECCCEEEHHHHHHHHHHHH
RGAVRAATWVVGQAPGLYDMQDVLGLK
CCCHHHHHEEEECCCCCCCHHHHHCCC
>Mature Secondary Structure
MIKIAVCGAAGRMGQRLINSVQEAEGVCLSGVLERPAHPLVGQDAGLVAGCGALGVSISD
CEEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCCCEEEHHHHCCCCCC
DLNAVIAGCDVLIDFTAPKVSLKNLEACGLQRKSIVIGSTGFTPEERQLAMELTRNISAI
CHHHHHHCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCHHEE
LAPNMSVGVNVCFKILKDIAATLGDDFDVEIVESHHRMKVDAPSGTAVRMGQVVAEALGR
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCHHHHHHHHHHHHCC
DYDRVANFHREGITGSRTKDEIGMQTIRGGDIVGEHTVYFIGMGERIELSHRAMNRDMFS
CHHHHHHHHHCCCCCCCCHHHHCHHHCCCCCEECCCEEEEEECCCEEEHHHHHHHHHHHH
RGAVRAATWVVGQAPGLYDMQDVLGLK
CCCHHHHHEEEECCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA