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The map label for this gene is prmA

Identifier: 118581364

GI number: 118581364

Start: 3230242

End: 3231171

Strand: Direct

Name: prmA

Synonym: Ppro_2959

Alternate gene names: 118581364

Gene position: 3230242-3231171 (Clockwise)

Preceding gene: 118581357

Following gene: 118581365

Centisome position: 80.59

GC content: 64.52

Gene sequence:

>930_bases
ATGACTACCCGCTGGCTTGAAATCACCTGTGACATTCCCGCCGATCTGGCCGACATCCTGGCCTCGTATCTGGGCGAACT
CTCCGGCACCGGCGTCTGCACCGAGAACCTGGACGTGGACGCATTTTCAACCGACGAAATCACCCTCTCCGCCATCAAAA
CGGTCAAGGCCTATTTCAGCGAAGATGAAGACGTGGATGCCCGGCTGGAGGAGATCCAGAACTTCCTCGACCGGCTTGCC
GAGCAGCATCCGGGCCTCTCCATCCCCAGGCCAATCATCTCCACGGTGCAGAGCGAAGACTGGAGCAGCAGCTGGAAGGC
AAACTTCAAGCCGCTACGCGTCGGCCGGCGACTGATGATCGTGCCGACCTGGGAGGAACCGCCGCCATATCCCGACGACA
TCGTGCTGCGCCTGGACCCGGGCATGGCCTTCGGCACCGGAGGGCACGAGACCACCCGCCTCTGCCTGGAGCTGCTGGAA
GAGATCATGGACGGCATGCCGATCCTGCTGACCCCAGCGGTGCTGGACCTGGGCACCGGCTCGGGCATCCTGGCCATGGC
TGCTGTCCGACTGGGCGCCGGCCGGGTCGTCGCGGTGGACATCGACCCCCAGGCGGTGGAAGTTGCCCGGGAAAACCTGG
CGCTCAACGACCTGACGGATCAGGTAGAGTGCGACACGACCCCCCTGGAGGCGCTCCCGGGGACCTTCGACGTCATCCTG
GCCAACATCCTTGCGGAAGAGCTGGTGCGTCTGGCACCGCAGCTGATCCAGCGCCTGTCGGTAGGAGGGATGCTGGTGCT
CTCCGGCATCCTGGCGGAAAGAGAGCAGCTGGTCCGCGCCGGATTCGCCTGCCAAGAGCTGGAATACCGTGAGACGCGGC
GGCAGGGTGAATGGGTGGCCATGGTCTACCGGAGAGCCGCACGAGCATGA

Upstream 100 bases:

>100_bases
TAATTAGAACAGTACTATTTGTCAAGGTTTTTATTGCCAGACGTGCAGCATATTGATAACATACCGAACTCATTTGAAAA
ACATAACCACAAGGAAACCC

Downstream 100 bases:

>100_bases
GCGGCCGGCGCTTCATGATCAGCTCCCGCAGCATCCAGGACAACCATGCCTGGCTGGAGGGGGACCTGTTCAGCCACATG
GTGCGGGTACTGCGGCTGGG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MTTRWLEITCDIPADLADILASYLGELSGTGVCTENLDVDAFSTDEITLSAIKTVKAYFSEDEDVDARLEEIQNFLDRLA
EQHPGLSIPRPIISTVQSEDWSSSWKANFKPLRVGRRLMIVPTWEEPPPYPDDIVLRLDPGMAFGTGGHETTRLCLELLE
EIMDGMPILLTPAVLDLGTGSGILAMAAVRLGAGRVVAVDIDPQAVEVARENLALNDLTDQVECDTTPLEALPGTFDVIL
ANILAEELVRLAPQLIQRLSVGGMLVLSGILAEREQLVRAGFACQELEYRETRRQGEWVAMVYRRAARA

Sequences:

>Translated_309_residues
MTTRWLEITCDIPADLADILASYLGELSGTGVCTENLDVDAFSTDEITLSAIKTVKAYFSEDEDVDARLEEIQNFLDRLA
EQHPGLSIPRPIISTVQSEDWSSSWKANFKPLRVGRRLMIVPTWEEPPPYPDDIVLRLDPGMAFGTGGHETTRLCLELLE
EIMDGMPILLTPAVLDLGTGSGILAMAAVRLGAGRVVAVDIDPQAVEVARENLALNDLTDQVECDTTPLEALPGTFDVIL
ANILAEELVRLAPQLIQRLSVGGMLVLSGILAEREQLVRAGFACQELEYRETRRQGEWVAMVYRRAARA
>Mature_308_residues
TTRWLEITCDIPADLADILASYLGELSGTGVCTENLDVDAFSTDEITLSAIKTVKAYFSEDEDVDARLEEIQNFLDRLAE
QHPGLSIPRPIISTVQSEDWSSSWKANFKPLRVGRRLMIVPTWEEPPPYPDDIVLRLDPGMAFGTGGHETTRLCLELLEE
IMDGMPILLTPAVLDLGTGSGILAMAAVRLGAGRVVAVDIDPQAVEVARENLALNDLTDQVECDTTPLEALPGTFDVILA
NILAEELVRLAPQLIQRLSVGGMLVLSGILAEREQLVRAGFACQELEYRETRRQGEWVAMVYRRAARA

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=169, Percent_Identity=42.603550295858, Blast_Score=116, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_PELPD (A1AT86)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902614.1
- ProteinModelPortal:   A1AT86
- STRING:   A1AT86
- GeneID:   4574465
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2959
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   AIDIDDW
- PhylomeDB:   A1AT86
- ProtClustDB:   CLSK827836
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33989; Mature: 33858

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTRWLEITCDIPADLADILASYLGELSGTGVCTENLDVDAFSTDEITLSAIKTVKAYFS
CCCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHC
EDEDVDARLEEIQNFLDRLAEQHPGLSIPRPIISTVQSEDWSSSWKANFKPLRVGRRLMI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHCCCEEEE
VPTWEEPPPYPDDIVLRLDPGMAFGTGGHETTRLCLELLEEIMDGMPILLTPAVLDLGTG
EECCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCC
SGILAMAAVRLGAGRVVAVDIDPQAVEVARENLALNDLTDQVECDTTPLEALPGTFDVIL
CHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHCCCHHHHHH
ANILAEELVRLAPQLIQRLSVGGMLVLSGILAEREQLVRAGFACQELEYRETRRQGEWVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHH
MVYRRAARA
HHHHHHHCC
>Mature Secondary Structure 
TTRWLEITCDIPADLADILASYLGELSGTGVCTENLDVDAFSTDEITLSAIKTVKAYFS
CCEEEEEEECCCHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHC
EDEDVDARLEEIQNFLDRLAEQHPGLSIPRPIISTVQSEDWSSSWKANFKPLRVGRRLMI
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHCCCEEEE
VPTWEEPPPYPDDIVLRLDPGMAFGTGGHETTRLCLELLEEIMDGMPILLTPAVLDLGTG
EECCCCCCCCCCCEEEEECCCCEECCCCHHHHHHHHHHHHHHHCCCCEEEHHHHHCCCCC
SGILAMAAVRLGAGRVVAVDIDPQAVEVARENLALNDLTDQVECDTTPLEALPGTFDVIL
CHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHCCCHHHHHH
ANILAEELVRLAPQLIQRLSVGGMLVLSGILAEREQLVRAGFACQELEYRETRRQGEWVA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHH
MVYRRAARA
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA