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The map label for this gene is obgE

Identifier: 118581359

GI number: 118581359

Start: 3224734

End: 3225750

Strand: Reverse

Name: obgE

Synonym: Ppro_2954

Alternate gene names: 118581359

Gene position: 3225750-3224734 (Counterclockwise)

Preceding gene: 118581360

Following gene: 118581358

Centisome position: 80.48

GC content: 65.59

Gene sequence:

>1017_bases
GTGAAATTCATCGACGAAGTAACCCTGTTCGCCTCTTCCGGCCATGGCGGCGCCGGCTGCGTGGCTTTCCGCCGCGAGAA
GTTCATCGAGTTCGGCGGTCCCAACGGCGGCGACGGCGGCAAGGGGGGGGATGTGGTTTTCGTGGCCAAGGCCGGGCTGT
CATCCCTGCTGGAGCTGCGCCACCGCCCGCACCAGAAGGCCGAGAAGGGACATAACGGGCAGGGGAAGAACCGCCATGGC
GCGTCCGGCGCCGATCTGGTGATCAAGGTTCCGGTGGGCACGGTGATCAGCGATGCCGAGAGCGGCGAGCAGTTGGCCGA
CCTGGCCGAGAACGGCCAACGGGTGGTGCTGCTCAAGGGGGGGCGCGGCGGACAGGGCAATGCCCGCTTTGCCTCCGCCA
CCCATAAGACCCCCCGTTTCGCCCAGCCGGGGGAAGAGGGGCAGGAGGCTAAGCTGCGGCTTGAGCTGAAGCTGATGGCC
GATGTGGGGCTTTTGGGGCTGCCCAATGCGGGCAAGTCGTCGCTGATAACCAAGATTTCTGCAGCGCGGCCCAAGATCGC
CGATTACCCCTTCACCACCATCAAGCCCTCCCTGGGGGTGGTGCCGTACAAAAACGCACGTTCCTTTGTCATGGCCGACA
TACCGGGCATCATCGAGGGGGCCCACGAGGGGGCCGGCCTGGGGCACCGCTTCCTCAAGCACCTGGAACGTTCCGGGATC
CTGCTGCACCTGGTGGACATCTCCTGGATGCCGGAGCGTGATCCCCTGGCCGAGTACGAGGCGGTCACCCGCGAACTGAC
CATGTTCAGCCCCGAGCTGGCGGCCAAGGAACAGGTGGTGGTGATCACCAAGCTGGACCTGCCCCAGACCCGCGAGAAAC
TGGCGGAGATCAGGAGCTGGTTCGAGGAGCGGGGCATCAGGGTCTTTCCGATCTCCTCCGCCACCGGCGAGGGGGTTGGC
GAACTTTTGGACGAGATCGCCCGCCGCCTGTGGGGCCGGATTGAAGAGGAGTGGTGA

Upstream 100 bases:

>100_bases
CTCTTTGACAGCCTGTTCGTAACCTTTCTGGAGGAGCGGCTGACGGACGCCTGGAACGGGCGCATCGTGGCCATCCAGGA
GTGGTTGGAGGGTAAGTGAC

Downstream 100 bases:

>100_bases
TGCGCCGGGAGCTTTTCAGGAAGATTAAGCGGGTGGTGGTCAAGATCGGCAGCAGGGTGCTGACAGACGATGAGGGCGCC
TTGGACATGGGGGTCATCGG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MKFIDEVTLFASSGHGGAGCVAFRREKFIEFGGPNGGDGGKGGDVVFVAKAGLSSLLELRHRPHQKAEKGHNGQGKNRHG
ASGADLVIKVPVGTVISDAESGEQLADLAENGQRVVLLKGGRGGQGNARFASATHKTPRFAQPGEEGQEAKLRLELKLMA
DVGLLGLPNAGKSSLITKISAARPKIADYPFTTIKPSLGVVPYKNARSFVMADIPGIIEGAHEGAGLGHRFLKHLERSGI
LLHLVDISWMPERDPLAEYEAVTRELTMFSPELAAKEQVVVITKLDLPQTREKLAEIRSWFEERGIRVFPISSATGEGVG
ELLDEIARRLWGRIEEEW

Sequences:

>Translated_338_residues
MKFIDEVTLFASSGHGGAGCVAFRREKFIEFGGPNGGDGGKGGDVVFVAKAGLSSLLELRHRPHQKAEKGHNGQGKNRHG
ASGADLVIKVPVGTVISDAESGEQLADLAENGQRVVLLKGGRGGQGNARFASATHKTPRFAQPGEEGQEAKLRLELKLMA
DVGLLGLPNAGKSSLITKISAARPKIADYPFTTIKPSLGVVPYKNARSFVMADIPGIIEGAHEGAGLGHRFLKHLERSGI
LLHLVDISWMPERDPLAEYEAVTRELTMFSPELAAKEQVVVITKLDLPQTREKLAEIRSWFEERGIRVFPISSATGEGVG
ELLDEIARRLWGRIEEEW
>Mature_338_residues
MKFIDEVTLFASSGHGGAGCVAFRREKFIEFGGPNGGDGGKGGDVVFVAKAGLSSLLELRHRPHQKAEKGHNGQGKNRHG
ASGADLVIKVPVGTVISDAESGEQLADLAENGQRVVLLKGGRGGQGNARFASATHKTPRFAQPGEEGQEAKLRLELKLMA
DVGLLGLPNAGKSSLITKISAARPKIADYPFTTIKPSLGVVPYKNARSFVMADIPGIIEGAHEGAGLGHRFLKHLERSGI
LLHLVDISWMPERDPLAEYEAVTRELTMFSPELAAKEQVVVITKLDLPQTREKLAEIRSWFEERGIRVFPISSATGEGVG
ELLDEIARRLWGRIEEEW

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=321, Percent_Identity=41.7445482866044, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI111955139, Length=362, Percent_Identity=35.3591160220994, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI111955063, Length=195, Percent_Identity=38.974358974359, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI58761500, Length=183, Percent_Identity=25.6830601092896, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI4758796, Length=176, Percent_Identity=26.7045454545455, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1789574, Length=332, Percent_Identity=48.4939759036145, Blast_Score=269, Evalue=2e-73,
Organism=Escherichia coli, GI1787454, Length=100, Percent_Identity=34, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1790615, Length=208, Percent_Identity=25.4807692307692, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17508313, Length=326, Percent_Identity=37.7300613496933, Blast_Score=155, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17552324, Length=312, Percent_Identity=30.7692307692308, Blast_Score=135, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17509631, Length=128, Percent_Identity=32.03125, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17555344, Length=101, Percent_Identity=34.6534653465347, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71981008, Length=123, Percent_Identity=31.7073170731707, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321962, Length=192, Percent_Identity=35.4166666666667, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=175, Percent_Identity=29.1428571428571, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321612, Length=87, Percent_Identity=39.0804597701149, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20129375, Length=339, Percent_Identity=39.8230088495575, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24585318, Length=292, Percent_Identity=36.6438356164384, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24640873, Length=141, Percent_Identity=30.4964539007092, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640877, Length=141, Percent_Identity=30.4964539007092, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640875, Length=141, Percent_Identity=30.4964539007092, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_PELPD (A1AT81)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902609.1
- ProteinModelPortal:   A1AT81
- SMR:   A1AT81
- STRING:   A1AT81
- GeneID:   4574494
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2954
- eggNOG:   COG0536
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- PhylomeDB:   A1AT81
- ProtClustDB:   PRK12299
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36506; Mature: 36506

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: PS00905 GTP1_OBG; PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDEVTLFASSGHGGAGCVAFRREKFIEFGGPNGGDGGKGGDVVFVAKAGLSSLLELR
CCCHHCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
HRPHQKAEKGHNGQGKNRHGASGADLVIKVPVGTVISDAESGEQLADLAENGQRVVLLKG
HCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHCCCEEEEEEC
GRGGQGNARFASATHKTPRFAQPGEEGQEAKLRLELKLMADVGLLGLPNAGKSSLITKIS
CCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCEEECCCCCCHHHHHHHH
AARPKIADYPFTTIKPSLGVVPYKNARSFVMADIPGIIEGAHEGAGLGHRFLKHLERSGI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHCCE
LLHLVDISWMPERDPLAEYEAVTRELTMFSPELAAKEQVVVITKLDLPQTREKLAEIRSW
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
FEERGIRVFPISSATGEGVGELLDEIARRLWGRIEEEW
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKFIDEVTLFASSGHGGAGCVAFRREKFIEFGGPNGGDGGKGGDVVFVAKAGLSSLLELR
CCCHHCEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHH
HRPHQKAEKGHNGQGKNRHGASGADLVIKVPVGTVISDAESGEQLADLAENGQRVVLLKG
HCCCHHHHCCCCCCCCCCCCCCCCCEEEEECCCCEECCCCCHHHHHHHHHCCCEEEEEEC
GRGGQGNARFASATHKTPRFAQPGEEGQEAKLRLELKLMADVGLLGLPNAGKSSLITKIS
CCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCEEECCCCCCHHHHHHHH
AARPKIADYPFTTIKPSLGVVPYKNARSFVMADIPGIIEGAHEGAGLGHRFLKHLERSGI
HCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHCCCCCCCHHHHHHHHHHHCCE
LLHLVDISWMPERDPLAEYEAVTRELTMFSPELAAKEQVVVITKLDLPQTREKLAEIRSW
EEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHH
FEERGIRVFPISSATGEGVGELLDEIARRLWGRIEEEW
HHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA