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The map label for this gene is hflX [H]

Identifier: 118581300

GI number: 118581300

Start: 3166585

End: 3168327

Strand: Direct

Name: hflX [H]

Synonym: Ppro_2895

Alternate gene names: 118581300

Gene position: 3166585-3168327 (Clockwise)

Preceding gene: 118581299

Following gene: 118581301

Centisome position: 79.01

GC content: 62.36

Gene sequence:

>1743_bases
TTGCCATCGGCCCGCGGACGCAGTATCCTGAAAAGCATCTTCAGATCCTGGCAGCAACGGAGTCATCCCATCAAAGAAGT
ATTCGGCAATCTCACGGGGCTGAAAACCAGCCAGATCCAGGCCCTTGAACGGCTCTACCGGCGGCGCATTCCCCAAGCCG
AGTTTTGCACCCAAGAACTGGCCGGCAGACTGGTGGAGCTTTCCCTCGACATCCGCCGCCAGATCGGCATCTTGGTCAAC
CGTTCCGGCATGGTGGAATACGTCATCGTCGGCGACGAACGGGGACTGGTCATTCCGGAACTGCGCGACTATCCCTTGGG
AAAGCGCCCCTTGCGCGGACTGCGCCTGATCCACACCCATTTAAAGAACGAGCAGGTCAGTGAAGACGACCTGACCGACC
TCTCCCTGCTTCGCCTGGACCTGCTGGCAGCCCTGCTGTTCTCTCCCGAAAAACGCAGAATTTCCGTTCAGATGGCCTGG
ATCTCCCCGACCAGCTCCGGTCCGTCGACCATTACCGGTGCGATCACTACTTTCGAGCGGGTCGACCTGGAGTGTGCCCG
CTTCCTGGAGGAACTGGAGGCTGACCTGTCGCGCTCCACGCGTGCCAAGAGCAGCGGCGTCGAGGCGCTGGAGCGTGCGA
TCCTGGTCTCCGTCACCGTGGAGGGGACACGCCAGGAGGCTGAGGATTCCATCATGGAACTGCGCGAACTGGCCCGCACC
GCGCAGATCGAGGTCCTGGACGAGTTCATCCAGCGGCCGCGCAGCATCAACCCCCGCTTCGTCATGGGAGAGGGCAAGAT
GCGCGACGTGGTCATCCGGGCCCTGCAGCACGGCGCCACCATGCTGATTTTCGACCAGGAGCTGACCCCGGCCCAGATCC
GGTCCATCTCTGCCATGACCGAGCTGAAAGCCATCGACCGCAGCCAGCTGATCCTGGACATCTTCGCCCGCCGCGCCCAG
ACCCTTGACGGCAAGGTTCAGGTGGAGCTGGCACAACTGAAATACCTGCTGCCGCGCCTGACCGGACGGGGCGTGCAGAT
GTCGCGGCTGATGGGGGGCATCGGGGGGCGCGGACCGGGCGAGACCAAGCTGGAGACCGACCGTCGCCGCATCCGCGACC
GCATCGCCAGCCTGGAACGCGAACTGAAGGAACTCTCCCGCGGCCGCGACCAGCGCAGGCGCAAGCGGGTCAAGGCCAGC
GTGCCGATCGTTTCCATCGTCGGCTATACCAACGCCGGCAAGTCCACCCTGCTCAACACCCTCACCAAGAGCAGGGTGTT
TACCGAGGACCTGCTCTTCGCCACCCTGGACACATCCACCCGCAGGCTGCGTTTCCCCCTCGAACGCGAGGTAATCATCA
CCGACACGGTCGGATTCATCCGTTCCCTCCCCGCATCGCTCTTGGGTGCCTTCAAGGCTACCCTGGAGGAACTGCGGGAC
GCCGATCTGCTGCTGCATGTGGTGGACGCTTCAAATCCCCGTTTCGAGACCCACATCCAACAGGTTAACCGCATCCTGGA
CGAACTGGAACTGGGCGACAAACCACGGCTTTTAATCTTCAACAAGTCCGACCTGCTCGCCAAACTGAAAAAGAGCGACA
CCATCGCCTTCCTGAGGGTGCGCCAGTTTGCCCGCACCTGCGGCGGCATCATGATTGCAGCCACCGACCGCACGAGCATG
TCACCACTCCTGGAGGAGTTGCAACGACGCTTCTGGCCGGACGAGTCGTCCCTGATTGATTGA

Upstream 100 bases:

>100_bases
GTAGCCTCCCCCAGCACGACACCCGAATAAAGAAGGCCCTGGATGCCGGAATGGTCCAGGGCCTCTACATTGCCACCTCA
CGGCCTGGAACGCCGCGCGC

Downstream 100 bases:

>100_bases
CATAAACCGCGATTTGCCTGTATAGTCTCGCACATCTCACAGATCCCGGAATGCCATGCAGGACCTCAAATATCTGACTG
AAAAAAAACGTTTCCCCCTG

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 580; Mature: 579

Protein sequence:

>580_residues
MPSARGRSILKSIFRSWQQRSHPIKEVFGNLTGLKTSQIQALERLYRRRIPQAEFCTQELAGRLVELSLDIRRQIGILVN
RSGMVEYVIVGDERGLVIPELRDYPLGKRPLRGLRLIHTHLKNEQVSEDDLTDLSLLRLDLLAALLFSPEKRRISVQMAW
ISPTSSGPSTITGAITTFERVDLECARFLEELEADLSRSTRAKSSGVEALERAILVSVTVEGTRQEAEDSIMELRELART
AQIEVLDEFIQRPRSINPRFVMGEGKMRDVVIRALQHGATMLIFDQELTPAQIRSISAMTELKAIDRSQLILDIFARRAQ
TLDGKVQVELAQLKYLLPRLTGRGVQMSRLMGGIGGRGPGETKLETDRRRIRDRIASLERELKELSRGRDQRRRKRVKAS
VPIVSIVGYTNAGKSTLLNTLTKSRVFTEDLLFATLDTSTRRLRFPLEREVIITDTVGFIRSLPASLLGAFKATLEELRD
ADLLLHVVDASNPRFETHIQQVNRILDELELGDKPRLLIFNKSDLLAKLKKSDTIAFLRVRQFARTCGGIMIAATDRTSM
SPLLEELQRRFWPDESSLID

Sequences:

>Translated_580_residues
MPSARGRSILKSIFRSWQQRSHPIKEVFGNLTGLKTSQIQALERLYRRRIPQAEFCTQELAGRLVELSLDIRRQIGILVN
RSGMVEYVIVGDERGLVIPELRDYPLGKRPLRGLRLIHTHLKNEQVSEDDLTDLSLLRLDLLAALLFSPEKRRISVQMAW
ISPTSSGPSTITGAITTFERVDLECARFLEELEADLSRSTRAKSSGVEALERAILVSVTVEGTRQEAEDSIMELRELART
AQIEVLDEFIQRPRSINPRFVMGEGKMRDVVIRALQHGATMLIFDQELTPAQIRSISAMTELKAIDRSQLILDIFARRAQ
TLDGKVQVELAQLKYLLPRLTGRGVQMSRLMGGIGGRGPGETKLETDRRRIRDRIASLERELKELSRGRDQRRRKRVKAS
VPIVSIVGYTNAGKSTLLNTLTKSRVFTEDLLFATLDTSTRRLRFPLEREVIITDTVGFIRSLPASLLGAFKATLEELRD
ADLLLHVVDASNPRFETHIQQVNRILDELELGDKPRLLIFNKSDLLAKLKKSDTIAFLRVRQFARTCGGIMIAATDRTSM
SPLLEELQRRFWPDESSLID
>Mature_579_residues
PSARGRSILKSIFRSWQQRSHPIKEVFGNLTGLKTSQIQALERLYRRRIPQAEFCTQELAGRLVELSLDIRRQIGILVNR
SGMVEYVIVGDERGLVIPELRDYPLGKRPLRGLRLIHTHLKNEQVSEDDLTDLSLLRLDLLAALLFSPEKRRISVQMAWI
SPTSSGPSTITGAITTFERVDLECARFLEELEADLSRSTRAKSSGVEALERAILVSVTVEGTRQEAEDSIMELRELARTA
QIEVLDEFIQRPRSINPRFVMGEGKMRDVVIRALQHGATMLIFDQELTPAQIRSISAMTELKAIDRSQLILDIFARRAQT
LDGKVQVELAQLKYLLPRLTGRGVQMSRLMGGIGGRGPGETKLETDRRRIRDRIASLERELKELSRGRDQRRRKRVKASV
PIVSIVGYTNAGKSTLLNTLTKSRVFTEDLLFATLDTSTRRLRFPLEREVIITDTVGFIRSLPASLLGAFKATLEELRDA
DLLLHVVDASNPRFETHIQQVNRILDELELGDKPRLLIFNKSDLLAKLKKSDTIAFLRVRQFARTCGGIMIAATDRTSMS
PLLEELQRRFWPDESSLID

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133116, Length=188, Percent_Identity=36.1702127659575, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI310133118, Length=205, Percent_Identity=34.1463414634146, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI310124269, Length=174, Percent_Identity=37.3563218390805, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI310124267, Length=174, Percent_Identity=37.3563218390805, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI310124171, Length=174, Percent_Identity=37.3563218390805, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI310124169, Length=174, Percent_Identity=37.3563218390805, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI1790615, Length=319, Percent_Identity=45.7680250783699, Blast_Score=280, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI17561038, Length=228, Percent_Identity=31.140350877193, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24650079, Length=333, Percent_Identity=30.03003003003, Blast_Score=119, Evalue=7e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 65748; Mature: 65617

Theoretical pI: Translated: 10.44; Mature: 10.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSARGRSILKSIFRSWQQRSHPIKEVFGNLTGLKTSQIQALERLYRRRIPQAEFCTQEL
CCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
AGRLVELSLDIRRQIGILVNRSGMVEYVIVGDERGLVIPELRDYPLGKRPLRGLRLIHTH
HHHHHHHHHHHHHHHCEEEECCCCEEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHH
LKNEQVSEDDLTDLSLLRLDLLAALLFSPEKRRISVQMAWISPTSSGPSTITGAITTFER
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHH
VDLECARFLEELEADLSRSTRAKSSGVEALERAILVSVTVEGTRQEAEDSIMELRELART
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHH
AQIEVLDEFIQRPRSINPRFVMGEGKMRDVVIRALQHGATMLIFDQELTPAQIRSISAMT
HHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHH
ELKAIDRSQLILDIFARRAQTLDGKVQVELAQLKYLLPRLTGRGVQMSRLMGGIGGRGPG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
ETKLETDRRRIRDRIASLERELKELSRGRDQRRRKRVKASVPIVSIVGYTNAGKSTLLNT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LTKSRVFTEDLLFATLDTSTRRLRFPLEREVIITDTVGFIRSLPASLLGAFKATLEELRD
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
ADLLLHVVDASNPRFETHIQQVNRILDELELGDKPRLLIFNKSDLLAKLKKSDTIAFLRV
HHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHH
RQFARTCGGIMIAATDRTSMSPLLEELQRRFWPDESSLID
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PSARGRSILKSIFRSWQQRSHPIKEVFGNLTGLKTSQIQALERLYRRRIPQAEFCTQEL
CCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
AGRLVELSLDIRRQIGILVNRSGMVEYVIVGDERGLVIPELRDYPLGKRPLRGLRLIHTH
HHHHHHHHHHHHHHHCEEEECCCCEEEEEEECCCCEECCCCCCCCCCCCCHHHHHHHHHH
LKNEQVSEDDLTDLSLLRLDLLAALLFSPEKRRISVQMAWISPTSSGPSTITGAITTFER
HCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHH
VDLECARFLEELEADLSRSTRAKSSGVEALERAILVSVTVEGTRQEAEDSIMELRELART
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHH
AQIEVLDEFIQRPRSINPRFVMGEGKMRDVVIRALQHGATMLIFDQELTPAQIRSISAMT
HHHHHHHHHHHCCCCCCCCEEECCCHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHH
ELKAIDRSQLILDIFARRAQTLDGKVQVELAQLKYLLPRLTGRGVQMSRLMGGIGGRGPG
HHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCC
ETKLETDRRRIRDRIASLERELKELSRGRDQRRRKRVKASVPIVSIVGYTNAGKSTLLNT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHH
LTKSRVFTEDLLFATLDTSTRRLRFPLEREVIITDTVGFIRSLPASLLGAFKATLEELRD
HHHHHHHHHHHHHHHCCCCCCEEECCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
ADLLLHVVDASNPRFETHIQQVNRILDELELGDKPRLLIFNKSDLLAKLKKSDTIAFLRV
HHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHCCCHHHHHHH
RQFARTCGGIMIAATDRTSMSPLLEELQRRFWPDESSLID
HHHHHHHCCEEEEECCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]