Click here to switch to the map view.

The map label for this gene is cobT [H]

Identifier: 118581213

GI number: 118581213

Start: 3070832

End: 3071890

Strand: Direct

Name: cobT [H]

Synonym: Ppro_2806

Alternate gene names: 118581213

Gene position: 3070832-3071890 (Clockwise)

Preceding gene: 118581212

Following gene: 118581214

Centisome position: 76.62

GC content: 64.21

Gene sequence:

>1059_bases
ATGAACAGGACTATCGTTGAAACCACTCGTGAGCGCATCAAACCGGTCAACCGGGAACTGATGCAACAGGCCCAGGCCAG
GCTGGACGCAAAGACCAAGCCGCCCGGCGCCCTGGGGCGTTTGGAGGAGTTCGCCCGCCGCATGGTGGCCATCAGCGGTA
CGGGTTCCCCGGACACGAGCAAAAAAGTCATCTACACCTTTGCCGGCGACCACGGCGTAACCGACGAAGGGGTGGCGCTC
TACCCCAAGGCGGTCACCACCCAGATGGTATACAACTTCCTGGCCGGCGGCGCCGGAGTCAACGTGCTGGCTCGTCATGT
GGGGGCCGAGGTGCGGGTGGTTGACGTGGGGGTGGACAACGATTTCGGCGACCTGGCCGGCGTGATCCACCGCAAGGTGG
CCCGCGGCACGCGCAATTTCGCCAAGGGGCCGGCAATGACCAGGGAGGAGATGCTGGCCGCCATAACGGTCGGCATAGAC
CTGGCGGAACAGTGCAGGGTCGAGGGCATCGCCCTGGTGGGTACCGGTGAAATGGGTATCGGCAACACCACCCCCTCCTC
GGCCATCATCGCCGCCATCTCCGGCAAGGCGGTCCGGGACGTGACCCACCGTGGCACCGGCATCGATGACGACGCACTTG
AACTAAAAATTCGCGTTATAGAACAGGGGCTTGCGATCAACCAGCCTGACTCCACCAACCCGCTGGATGTGCTGGCCAAG
GTGGGAGGACTGGAGATCGCCGCCATCGCCGGCCTGGTGCTGGGCTGCGCCGCCAACGGGATCCCGGTGGTCATCGATGG
CTTCATCTCCACCGCCGGTGCGCTGATCGCCTCGGAACTGCACCCCAACGTAGCCGACTACATCTTCGCCGCGCACCGTT
CCATGGAAATCGGGCACAGTTTCATGCTGGAACGCATCGGAGTCGAGCCGATTCTGGACCTGAACCTGCGCCTGGGCGAA
GGCACGGGCGCCGCCCTGGCCATGTCCCTGATCGAGGCGGGGGTCAAGACCCTGAACGAGATGGCAACCCGCGAGCAGGC
CGGGGTTACCCACGAATAA

Upstream 100 bases:

>100_bases
GGCTCTGGCGGCAACGGCGGACGAGGCCTGGCTGGTGGCCAGCGGCATACCGCTGCGCCTTAAATAGGATAAGAACTCTT
TCACAGATATGGAGCACCCC

Downstream 100 bases:

>100_bases
TGCGGCTGTACATCATTGCCATGCAGTTTCTGACCATCATCCCGCTCCCCTGCAGGCACCTGTGGCAACGGGATGATCTG
GGGCGTTCCCTGGCTGTTTT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MNRTIVETTRERIKPVNRELMQQAQARLDAKTKPPGALGRLEEFARRMVAISGTGSPDTSKKVIYTFAGDHGVTDEGVAL
YPKAVTTQMVYNFLAGGAGVNVLARHVGAEVRVVDVGVDNDFGDLAGVIHRKVARGTRNFAKGPAMTREEMLAAITVGID
LAEQCRVEGIALVGTGEMGIGNTTPSSAIIAAISGKAVRDVTHRGTGIDDDALELKIRVIEQGLAINQPDSTNPLDVLAK
VGGLEIAAIAGLVLGCAANGIPVVIDGFISTAGALIASELHPNVADYIFAAHRSMEIGHSFMLERIGVEPILDLNLRLGE
GTGAALAMSLIEAGVKTLNEMATREQAGVTHE

Sequences:

>Translated_352_residues
MNRTIVETTRERIKPVNRELMQQAQARLDAKTKPPGALGRLEEFARRMVAISGTGSPDTSKKVIYTFAGDHGVTDEGVAL
YPKAVTTQMVYNFLAGGAGVNVLARHVGAEVRVVDVGVDNDFGDLAGVIHRKVARGTRNFAKGPAMTREEMLAAITVGID
LAEQCRVEGIALVGTGEMGIGNTTPSSAIIAAISGKAVRDVTHRGTGIDDDALELKIRVIEQGLAINQPDSTNPLDVLAK
VGGLEIAAIAGLVLGCAANGIPVVIDGFISTAGALIASELHPNVADYIFAAHRSMEIGHSFMLERIGVEPILDLNLRLGE
GTGAALAMSLIEAGVKTLNEMATREQAGVTHE
>Mature_352_residues
MNRTIVETTRERIKPVNRELMQQAQARLDAKTKPPGALGRLEEFARRMVAISGTGSPDTSKKVIYTFAGDHGVTDEGVAL
YPKAVTTQMVYNFLAGGAGVNVLARHVGAEVRVVDVGVDNDFGDLAGVIHRKVARGTRNFAKGPAMTREEMLAAITVGID
LAEQCRVEGIALVGTGEMGIGNTTPSSAIIAAISGKAVRDVTHRGTGIDDDALELKIRVIEQGLAINQPDSTNPLDVLAK
VGGLEIAAIAGLVLGCAANGIPVVIDGFISTAGALIASELHPNVADYIFAAHRSMEIGHSFMLERIGVEPILDLNLRLGE
GTGAALAMSLIEAGVKTLNEMATREQAGVTHE

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=330, Percent_Identity=40.6060606060606, Blast_Score=248, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36974; Mature: 36974

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRTIVETTRERIKPVNRELMQQAQARLDAKTKPPGALGRLEEFARRMVAISGTGSPDTS
CCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCC
KKVIYTFAGDHGVTDEGVALYPKAVTTQMVYNFLAGGAGVNVLARHVGAEVRVVDVGVDN
CEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEECCCC
DFGDLAGVIHRKVARGTRNFAKGPAMTREEMLAAITVGIDLAEQCRVEGIALVGTGEMGI
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCC
GNTTPSSAIIAAISGKAVRDVTHRGTGIDDDALELKIRVIEQGLAINQPDSTNPLDVLAK
CCCCCCHHEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VGGLEIAAIAGLVLGCAANGIPVVIDGFISTAGALIASELHPNVADYIFAAHRSMEIGHS
HCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FMLERIGVEPILDLNLRLGEGTGAALAMSLIEAGVKTLNEMATREQAGVTHE
HHHHHHCCCCEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNRTIVETTRERIKPVNRELMQQAQARLDAKTKPPGALGRLEEFARRMVAISGTGSPDTS
CCCCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHEEEECCCCCCCC
KKVIYTFAGDHGVTDEGVALYPKAVTTQMVYNFLAGGAGVNVLARHVGAEVRVVDVGVDN
CEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHCCCCHHHHHHHCCCEEEEEEECCCC
DFGDLAGVIHRKVARGTRNFAKGPAMTREEMLAAITVGIDLAEQCRVEGIALVGTGEMGI
CHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCHHHHHCCCCEEEEECCCCCC
GNTTPSSAIIAAISGKAVRDVTHRGTGIDDDALELKIRVIEQGLAINQPDSTNPLDVLAK
CCCCCCHHEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
VGGLEIAAIAGLVLGCAANGIPVVIDGFISTAGALIASELHPNVADYIFAAHRSMEIGHS
HCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FMLERIGVEPILDLNLRLGEGTGAALAMSLIEAGVKTLNEMATREQAGVTHE
HHHHHHCCCCEEECEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA