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The map label for this gene is ruvC

Identifier: 118581083

GI number: 118581083

Start: 2905790

End: 2906320

Strand: Reverse

Name: ruvC

Synonym: Ppro_2672

Alternate gene names: 118581083

Gene position: 2906320-2905790 (Counterclockwise)

Preceding gene: 118581084

Following gene: 118581082

Centisome position: 72.51

GC content: 60.83

Gene sequence:

>531_bases
ATGAGAGTTCTCGGTATCGATCCAGGATCGCGCATTACGGGGTATGGCATTGTGGAACAGGCGGGAAGTCGCCTTATCCA
TGTGGATAACGGTGCCATCTTCACCGACAGCGCCTTGGATTTTCCCGGACGCTTGAAGTCCATCTTCGATGGTTTGACCA
CGGTGATCGCCGAGTATGAACCGGATGAGGTCGCGGTCGAAAACGTTTTTCTGTCGAACAACGCCCAGAGCGCCCTGAAG
CTGGGCCAGGCACGTGGGGCGGCCATTGTGGCTGCCGTCCACGCCGGCCTGCCGGTGGCCGAATATACGGCGCTGCAGGT
GAAGCAGGCCGTGGTCGGGCGCGGCAAGGCCGCGAAGGAGCAGGTGCAGAAGATGCTCACTGCGCTTCTGTCCCTTCCCG
AAGTCGCCCAAGCCGATGCCTCCGACGCCCTGGCAGTAGCCGTCTGTCATTTGCACTCCCACCACCTTGTCCGCACATCC
GCTTCCGCGGTGCCGCATCGCGCGACATCATGGAGGAACTTCAAACCATGA

Upstream 100 bases:

>100_bases
GATGAGATGGAAAAGATGATGTAGGCCAGGGCGAGAGGGGGCGCGGTGGACACATTCTCCATGGCCGCCTCCCTGTTCTT
GCCAATGGCTGTCGGTGATC

Downstream 100 bases:

>100_bases
TTGCTCTTTTGACCGGTCAGATCGCGCAAAAGTCTCCTGATCATATCATCCTCGATGTGAACGGCGTCGGCTATCGGGTG
CAGATACCGTTTTCAACCTA

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRVLGIDPGSRITGYGIVEQAGSRLIHVDNGAIFTDSALDFPGRLKSIFDGLTTVIAEYEPDEVAVENVFLSNNAQSALK
LGQARGAAIVAAVHAGLPVAEYTALQVKQAVVGRGKAAKEQVQKMLTALLSLPEVAQADASDALAVAVCHLHSHHLVRTS
ASAVPHRATSWRNFKP

Sequences:

>Translated_176_residues
MRVLGIDPGSRITGYGIVEQAGSRLIHVDNGAIFTDSALDFPGRLKSIFDGLTTVIAEYEPDEVAVENVFLSNNAQSALK
LGQARGAAIVAAVHAGLPVAEYTALQVKQAVVGRGKAAKEQVQKMLTALLSLPEVAQADASDALAVAVCHLHSHHLVRTS
ASAVPHRATSWRNFKP
>Mature_176_residues
MRVLGIDPGSRITGYGIVEQAGSRLIHVDNGAIFTDSALDFPGRLKSIFDGLTTVIAEYEPDEVAVENVFLSNNAQSALK
LGQARGAAIVAAVHAGLPVAEYTALQVKQAVVGRGKAAKEQVQKMLTALLSLPEVAQADASDALAVAVCHLHSHHLVRTS
ASAVPHRATSWRNFKP

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=150, Percent_Identity=57.3333333333333, Blast_Score=153, Evalue=6e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_PELPD (A1ASF5)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902333.1
- ProteinModelPortal:   A1ASF5
- SMR:   A1ASF5
- STRING:   A1ASF5
- GeneID:   4574018
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2672
- eggNOG:   COG0817
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- PhylomeDB:   A1ASF5
- ProtClustDB:   PRK00039
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18585; Mature: 18585

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIDPGSRITGYGIVEQAGSRLIHVDNGAIFTDSALDFPGRLKSIFDGLTTVIAEYE
CEEECCCCCCCCCCCHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCC
PDEVAVENVFLSNNAQSALKLGQARGAAIVAAVHAGLPVAEYTALQVKQAVVGRGKAAKE
CCHHHHHHEEECCCHHHHHHHHHCCCHHHEEHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
QVQKMLTALLSLPEVAQADASDALAVAVCHLHSHHLVRTSASAVPHRATSWRNFKP
HHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGIDPGSRITGYGIVEQAGSRLIHVDNGAIFTDSALDFPGRLKSIFDGLTTVIAEYE
CEEECCCCCCCCCCCHHHHHCCCEEEEECCCCEEECCCCCCCHHHHHHHHHHHHHHHCCC
PDEVAVENVFLSNNAQSALKLGQARGAAIVAAVHAGLPVAEYTALQVKQAVVGRGKAAKE
CCHHHHHHEEECCCHHHHHHHHHCCCHHHEEHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
QVQKMLTALLSLPEVAQADASDALAVAVCHLHSHHLVRTSASAVPHRATSWRNFKP
HHHHHHHHHHCCCHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA