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The map label for this gene is ruvA

Identifier: 118581082

GI number: 118581082

Start: 2905197

End: 2905793

Strand: Reverse

Name: ruvA

Synonym: Ppro_2671

Alternate gene names: 118581082

Gene position: 2905793-2905197 (Counterclockwise)

Preceding gene: 118581083

Following gene: 118581081

Centisome position: 72.5

GC content: 57.12

Gene sequence:

>597_bases
ATGATTGCTCTTTTGACCGGTCAGATCGCGCAAAAGTCTCCTGATCATATCATCCTCGATGTGAACGGCGTCGGCTATCG
GGTGCAGATACCGTTTTCAACCTATTATGACCTTCCCGAAGAAGGAACGGTCAGTCTGCACATACACACCAGCGTGCGCG
AGGATGCCATCCAGTTGTACGGTTTCCGCACCAGCCTGGAGAAGTCGTTCTTCCAGCTGCTGCTTTCCGTATCCGGAGTC
GGTCCCCGTCTGGCACGGGATATCCTCTCCAATATCCAACCAGCTCAGCTGGCCCAGGCTCTTGGGCAGGGCGATATCCG
CATGCTTTCTGCCGTACCAGGCATCGGCAAAAAGACCGCTGAACGCCTGGTTCTGGAGCTGAAGGAAAAGGTGGGCAAGC
TGGATCTGTCATCCGTGGTGGTGCCCGAGCCGCGGCAGATGCCGGAGGATGATCTGCTTGAGGATGTGGTCTCGGCGCTT
CTTAACCTGGGCTATAAGGAGCCTCAGGTACGCAAGGTGCTGGCTGGTTTGAACCCCGGGTCGGATGCCTCGCTGGAGGG
GGTGCTCAAGCAGGCGCTGAAATCCCTGATGAGATAG

Upstream 100 bases:

>100_bases
CCCTGGCAGTAGCCGTCTGTCATTTGCACTCCCACCACCTTGTCCGCACATCCGCTTCCGCGGTGCCGCATCGCGCGACA
TCATGGAGGAACTTCAAACC

Downstream 100 bases:

>100_bases
ACGCAGGCGGTTGCTGTTGTTGCATCCGCTTCTGCGGGCTGGAAGCAGGGGTTTCGTTTCGGTCGTGTTGCCGGGCCTTG
TGTAATCCCCTTTTTTCTTG

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MIALLTGQIAQKSPDHIILDVNGVGYRVQIPFSTYYDLPEEGTVSLHIHTSVREDAIQLYGFRTSLEKSFFQLLLSVSGV
GPRLARDILSNIQPAQLAQALGQGDIRMLSAVPGIGKKTAERLVLELKEKVGKLDLSSVVVPEPRQMPEDDLLEDVVSAL
LNLGYKEPQVRKVLAGLNPGSDASLEGVLKQALKSLMR

Sequences:

>Translated_198_residues
MIALLTGQIAQKSPDHIILDVNGVGYRVQIPFSTYYDLPEEGTVSLHIHTSVREDAIQLYGFRTSLEKSFFQLLLSVSGV
GPRLARDILSNIQPAQLAQALGQGDIRMLSAVPGIGKKTAERLVLELKEKVGKLDLSSVVVPEPRQMPEDDLLEDVVSAL
LNLGYKEPQVRKVLAGLNPGSDASLEGVLKQALKSLMR
>Mature_198_residues
MIALLTGQIAQKSPDHIILDVNGVGYRVQIPFSTYYDLPEEGTVSLHIHTSVREDAIQLYGFRTSLEKSFFQLLLSVSGV
GPRLARDILSNIQPAQLAQALGQGDIRMLSAVPGIGKKTAERLVLELKEKVGKLDLSSVVVPEPRQMPEDDLLEDVVSAL
LNLGYKEPQVRKVLAGLNPGSDASLEGVLKQALKSLMR

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=204, Percent_Identity=37.7450980392157, Blast_Score=134, Evalue=3e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PELPD (A1ASF4)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_902332.1
- ProteinModelPortal:   A1ASF4
- SMR:   A1ASF4
- STRING:   A1ASF4
- GeneID:   4574017
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_2671
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   A1ASF4
- ProtClustDB:   PRK00116
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21582; Mature: 21582

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIALLTGQIAQKSPDHIILDVNGVGYRVQIPFSTYYDLPEEGTVSLHIHTSVREDAIQLY
CEEEEECHHHCCCCCEEEEEECCCCEEEEECHHHHCCCCCCCEEEEEEECCHHHHHHHHH
GFRTSLEKSFFQLLLSVSGVGPRLARDILSNIQPAQLAQALGQGDIRMLSAVPGIGKKTA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHCCCCCHHHH
ERLVLELKEKVGKLDLSSVVVPEPRQMPEDDLLEDVVSALLNLGYKEPQVRKVLAGLNPG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
SDASLEGVLKQALKSLMR
CCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MIALLTGQIAQKSPDHIILDVNGVGYRVQIPFSTYYDLPEEGTVSLHIHTSVREDAIQLY
CEEEEECHHHCCCCCEEEEEECCCCEEEEECHHHHCCCCCCCEEEEEEECCHHHHHHHHH
GFRTSLEKSFFQLLLSVSGVGPRLARDILSNIQPAQLAQALGQGDIRMLSAVPGIGKKTA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHCCCCCHHHH
ERLVLELKEKVGKLDLSSVVVPEPRQMPEDDLLEDVVSALLNLGYKEPQVRKVLAGLNPG
HHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
SDASLEGVLKQALKSLMR
CCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA