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The map label for this gene is tkt [H]

Identifier: 118581013

GI number: 118581013

Start: 2824415

End: 2826421

Strand: Reverse

Name: tkt [H]

Synonym: Ppro_2601

Alternate gene names: 118581013

Gene position: 2826421-2824415 (Counterclockwise)

Preceding gene: 118581014

Following gene: 118581012

Centisome position: 70.52

GC content: 66.77

Gene sequence:

>2007_bases
ATGCAACAGACAGCGATTTCAGCGACCGAGGCACGGCTCTGCGCCGATGCGATCCGTTTTCTCTCCGTCGATGCGGTGGA
ACAGGCGAATTCCGGTCACCCCGGTCTCCCCATGGGAGCGGCCGACTGCGCCTTTGCCCTGTGGGGAAACTACCTGAATT
TCAATCCGGCCGATCCCTGTTGGCCCAACCGGGACCGTTTCGTGCTCTCGGCCGGCCATGGCTCCATGCTGCTCTATTCG
CTGCTGCACCTGTTCGGCTATGACCTCCCCCTGGATGAGCTGAAGAACTTCCGCCAGTGGGGCAGCAAGACCCCCGGTCA
CCCCGAATTCGGCCATACCGTGGGGGTGGAGGTCACCACCGGACCGCTGGGGCAGGGCTTTGCCAACGGCGTCGGCATGG
CCATCGCCGCCAAGATGGCAGCCGAGCGCTTCAATACGACCGATTTCAAGCCGGTGGACCACACCATCTATGCCCTGGCC
GGTGACGGATGCCTGCAGGAGGGGATCAGCTACGAGGCCGCGGCCCTGGCAGGGCACCTCAAGCTGGGCAACCTGGTCTA
CATCTACGATGACAACGGCATTACCATCGAGGGGAAGACCAACCTGGCCTGGTCCGAGGATGTGGCCGGACGCTTCACCG
CCTGCGGCTGGCACGTGCAGAAGATCGATGGTCACGACTACGGCCAGATCACGGCGGCAATCGCCGCCGCCAAGGCGGAG
ACCGGGTGCCCCTCGCTGATCATCGCCACCACCCACATCGCCTTTGGCAGTCCGGCCAAGCAGGACTCCTCCGGCGCCCA
CGGCTCCCCCCTGGGCAAGGACGAGATCGCCGCCACCCGAGCCAACCTGGGCTGGAGCCACGCCCCCTTCCAGGTTCCCC
AGGAGGTGCGCGACATCTGTGGTGGCAGGGTGGAGCAGCTGAAGCAGCGCTACGATGAGTGGCAGCGCGGCTTTGCTGCA
TGGCGCAGCGCCAACCCCGACAAGGCCCTGCTGTGGGACCAGATGTGGAGCAAACCGCTCCCCCCTAACCTGACCGATGA
ACTGATCAATGCCGTGGCAGGCAAGGCTGGCGCCACCCGCTCACTCTCCGGTGCCGTGCTGCAGAAGGTAGCCTCCCTGC
TCCCCGCCCTGGCCGGCGGTTCCGCCGACCTGGCGCCCTCCAACAACAGCGATATCAAGGGAGCCGCATCGGTGCAGCCC
GGTGCGTTCGCAGGGCGCAACCTGCACTTCGGCATCCGCGAGCACGCCATGGGCGCCATCATGAACGGCATGGCCCTCTA
CGGATGCTTCATCCCCTACGGCGCCACCTTCCTGGTCTTCTCCGATTACTGTCGCTCGGCCGTGCGTCTGGCCGCCCTGA
TGAATCTGCGGCTGGTCTACCTGTTCACCCACGATTCCTTCTTCGTGGGTGAGGACGGCCCGACCCACCAGCCCATCGAG
CAGACCGCCTCGCTGCGCATGATCCCCGGCCTGCAGGTGATCCGCCCGGCCGACGGCCTGGAGACGGCCCTGGCCTGGAA
CGCCGCCCTGAACTACACCAATGGCCCCACCGCCCTGATCCTGTCGCGCCAGAACCTGCCGGTCATCGCCCGCGGCAGCG
GCTTCTGCACCACCGACGTGCTCAAGGGGGGCTACCCGGTCGCCTCTCCCGAAGGGGCACCGGATGCGGTCATCATGGCC
AGCGGCTCCGAGGTGCACGTGGCCCAGGAGGCGGCGGAACTGCTGGCGGCCCAGGGTGTCGTTGCCCGGGTCGTCTCGGT
CCCCTGCCTGGAGACGTTCATGGCCCAGCCCCAGTCCTACCGTGACGGCCTGCTTCCGGCCGGAATACCGCGCATCGCCG
TTGAGGCGGGGCGCGGCGAGTCCTGGGGACGGCTCCTGGGGTGCGACGGCCTGTTCATCGGCATCGAGCACTTTGGTGCC
TCGGCGCCGGGAGATGTGCTGGCCAGGCAGTTCGGCCTCACTCCGCCCCAGGTGGCCGAGAAGATCGCCGTCTTCCTGAA
GAGGTAA

Upstream 100 bases:

>100_bases
AGTTTTTCAGGGGTGGAGGTCGTCATGGAGGACGGCAGCCGTTACATCCCCCGAAAACCAGGCTTTACCCATTCAATCTG
ACAACTCAAAAGGAACAGCG

Downstream 100 bases:

>100_bases
GCGTCCGTACATGGAACTGGTGGAACAGCTGAAACAGTCCCTGCTCTTCTCCGGTCTGTCCGGTGATGACCTGGCCGACC
TGGCCACCATCACCGTGCGA

Product: transketolase

Products: NA

Alternate protein names: TK [H]

Number of amino acids: Translated: 668; Mature: 668

Protein sequence:

>668_residues
MQQTAISATEARLCADAIRFLSVDAVEQANSGHPGLPMGAADCAFALWGNYLNFNPADPCWPNRDRFVLSAGHGSMLLYS
LLHLFGYDLPLDELKNFRQWGSKTPGHPEFGHTVGVEVTTGPLGQGFANGVGMAIAAKMAAERFNTTDFKPVDHTIYALA
GDGCLQEGISYEAAALAGHLKLGNLVYIYDDNGITIEGKTNLAWSEDVAGRFTACGWHVQKIDGHDYGQITAAIAAAKAE
TGCPSLIIATTHIAFGSPAKQDSSGAHGSPLGKDEIAATRANLGWSHAPFQVPQEVRDICGGRVEQLKQRYDEWQRGFAA
WRSANPDKALLWDQMWSKPLPPNLTDELINAVAGKAGATRSLSGAVLQKVASLLPALAGGSADLAPSNNSDIKGAASVQP
GAFAGRNLHFGIREHAMGAIMNGMALYGCFIPYGATFLVFSDYCRSAVRLAALMNLRLVYLFTHDSFFVGEDGPTHQPIE
QTASLRMIPGLQVIRPADGLETALAWNAALNYTNGPTALILSRQNLPVIARGSGFCTTDVLKGGYPVASPEGAPDAVIMA
SGSEVHVAQEAAELLAAQGVVARVVSVPCLETFMAQPQSYRDGLLPAGIPRIAVEAGRGESWGRLLGCDGLFIGIEHFGA
SAPGDVLARQFGLTPPQVAEKIAVFLKR

Sequences:

>Translated_668_residues
MQQTAISATEARLCADAIRFLSVDAVEQANSGHPGLPMGAADCAFALWGNYLNFNPADPCWPNRDRFVLSAGHGSMLLYS
LLHLFGYDLPLDELKNFRQWGSKTPGHPEFGHTVGVEVTTGPLGQGFANGVGMAIAAKMAAERFNTTDFKPVDHTIYALA
GDGCLQEGISYEAAALAGHLKLGNLVYIYDDNGITIEGKTNLAWSEDVAGRFTACGWHVQKIDGHDYGQITAAIAAAKAE
TGCPSLIIATTHIAFGSPAKQDSSGAHGSPLGKDEIAATRANLGWSHAPFQVPQEVRDICGGRVEQLKQRYDEWQRGFAA
WRSANPDKALLWDQMWSKPLPPNLTDELINAVAGKAGATRSLSGAVLQKVASLLPALAGGSADLAPSNNSDIKGAASVQP
GAFAGRNLHFGIREHAMGAIMNGMALYGCFIPYGATFLVFSDYCRSAVRLAALMNLRLVYLFTHDSFFVGEDGPTHQPIE
QTASLRMIPGLQVIRPADGLETALAWNAALNYTNGPTALILSRQNLPVIARGSGFCTTDVLKGGYPVASPEGAPDAVIMA
SGSEVHVAQEAAELLAAQGVVARVVSVPCLETFMAQPQSYRDGLLPAGIPRIAVEAGRGESWGRLLGCDGLFIGIEHFGA
SAPGDVLARQFGLTPPQVAEKIAVFLKR
>Mature_668_residues
MQQTAISATEARLCADAIRFLSVDAVEQANSGHPGLPMGAADCAFALWGNYLNFNPADPCWPNRDRFVLSAGHGSMLLYS
LLHLFGYDLPLDELKNFRQWGSKTPGHPEFGHTVGVEVTTGPLGQGFANGVGMAIAAKMAAERFNTTDFKPVDHTIYALA
GDGCLQEGISYEAAALAGHLKLGNLVYIYDDNGITIEGKTNLAWSEDVAGRFTACGWHVQKIDGHDYGQITAAIAAAKAE
TGCPSLIIATTHIAFGSPAKQDSSGAHGSPLGKDEIAATRANLGWSHAPFQVPQEVRDICGGRVEQLKQRYDEWQRGFAA
WRSANPDKALLWDQMWSKPLPPNLTDELINAVAGKAGATRSLSGAVLQKVASLLPALAGGSADLAPSNNSDIKGAASVQP
GAFAGRNLHFGIREHAMGAIMNGMALYGCFIPYGATFLVFSDYCRSAVRLAALMNLRLVYLFTHDSFFVGEDGPTHQPIE
QTASLRMIPGLQVIRPADGLETALAWNAALNYTNGPTALILSRQNLPVIARGSGFCTTDVLKGGYPVASPEGAPDAVIMA
SGSEVHVAQEAAELLAAQGVVARVVSVPCLETFMAQPQSYRDGLLPAGIPRIAVEAGRGESWGRLLGCDGLFIGIEHFGA
SAPGDVLARQFGLTPPQVAEKIAVFLKR

Specific function: Unknown

COG id: COG0021

COG function: function code G; Transketolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transketolase family [H]

Homologues:

Organism=Homo sapiens, GI205277463, Length=584, Percent_Identity=28.5958904109589, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4507521, Length=584, Percent_Identity=28.5958904109589, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI133778974, Length=576, Percent_Identity=26.3888888888889, Blast_Score=137, Evalue=4e-32,
Organism=Homo sapiens, GI225637459, Length=595, Percent_Identity=22.5210084033613, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI225637461, Length=519, Percent_Identity=23.121387283237, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI225637463, Length=519, Percent_Identity=23.121387283237, Blast_Score=91, Evalue=5e-18,
Organism=Escherichia coli, GI1788808, Length=655, Percent_Identity=49.0076335877863, Blast_Score=613, Evalue=1e-177,
Organism=Escherichia coli, GI48994911, Length=662, Percent_Identity=48.3383685800604, Blast_Score=613, Evalue=1e-176,
Organism=Caenorhabditis elegans, GI17539652, Length=575, Percent_Identity=27.304347826087, Blast_Score=161, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6325331, Length=663, Percent_Identity=46.3046757164404, Blast_Score=532, Evalue=1e-152,
Organism=Saccharomyces cerevisiae, GI6319593, Length=669, Percent_Identity=43.3482810164424, Blast_Score=510, Evalue=1e-145,
Organism=Drosophila melanogaster, GI45551847, Length=678, Percent_Identity=25.5162241887906, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI45550715, Length=678, Percent_Identity=25.5162241887906, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24645119, Length=637, Percent_Identity=25.5886970172684, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24666278, Length=574, Percent_Identity=25.2613240418118, Blast_Score=140, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005478
- InterPro:   IPR020826
- InterPro:   IPR005476
- InterPro:   IPR005474 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C; PF00456 Transketolase_N [H]

EC number: =2.2.1.1 [H]

Molecular weight: Translated: 70833; Mature: 70833

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00801 TRANSKETOLASE_1 ; PS00802 TRANSKETOLASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTAISATEARLCADAIRFLSVDAVEQANSGHPGLPMGAADCAFALWGNYLNFNPADPC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
WPNRDRFVLSAGHGSMLLYSLLHLFGYDLPLDELKNFRQWGSKTPGHPEFGHTVGVEVTT
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
GPLGQGFANGVGMAIAAKMAAERFNTTDFKPVDHTIYALAGDGCLQEGISYEAAALAGHL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHCCCHHHHHHHCEE
KLGNLVYIYDDNGITIEGKTNLAWSEDVAGRFTACGWHVQKIDGHDYGQITAAIAAAKAE
EECCEEEEECCCCEEEECCCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHHHC
TGCPSLIIATTHIAFGSPAKQDSSGAHGSPLGKDEIAATRANLGWSHAPFQVPQEVRDIC
CCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHC
GGRVEQLKQRYDEWQRGFAAWRSANPDKALLWDQMWSKPLPPNLTDELINAVAGKAGATR
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
SLSGAVLQKVASLLPALAGGSADLAPSNNSDIKGAASVQPGAFAGRNLHFGIREHAMGAI
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHH
MNGMALYGCFIPYGATFLVFSDYCRSAVRLAALMNLRLVYLFTHDSFFVGEDGPTHQPIE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEECCCCCCCCCHH
QTASLRMIPGLQVIRPADGLETALAWNAALNYTNGPTALILSRQNLPVIARGSGFCTTDV
HHCCEEECCCCEEECCCCCHHHHHHHHHEEECCCCCEEEEEECCCCCEEECCCCCEEHHH
LKGGYPVASPEGAPDAVIMASGSEVHVAQEAAELLAAQGVVARVVSVPCLETFMAQPQSY
HCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RDGLLPAGIPRIAVEAGRGESWGRLLGCDGLFIGIEHFGASAPGDVLARQFGLTPPQVAE
HCCCCCCCCCCEEEECCCCCCCCEEECCCEEEEEHHHCCCCCCHHHHHHHHCCCCHHHHH
KIAVFLKR
HHHHHHCC
>Mature Secondary Structure
MQQTAISATEARLCADAIRFLSVDAVEQANSGHPGLPMGAADCAFALWGNYLNFNPADPC
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCC
WPNRDRFVLSAGHGSMLLYSLLHLFGYDLPLDELKNFRQWGSKTPGHPEFGHTVGVEVTT
CCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCEEEEEEEC
GPLGQGFANGVGMAIAAKMAAERFNTTDFKPVDHTIYALAGDGCLQEGISYEAAALAGHL
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCHHHHHCCCHHHHHHHCEE
KLGNLVYIYDDNGITIEGKTNLAWSEDVAGRFTACGWHVQKIDGHDYGQITAAIAAAKAE
EECCEEEEECCCCEEEECCCCCCCCCCCCCCEEECCEEEEEECCCCCHHHHHHHHHHHHC
TGCPSLIIATTHIAFGSPAKQDSSGAHGSPLGKDEIAATRANLGWSHAPFQVPQEVRDIC
CCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHC
GGRVEQLKQRYDEWQRGFAAWRSANPDKALLWDQMWSKPLPPNLTDELINAVAGKAGATR
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
SLSGAVLQKVASLLPALAGGSADLAPSNNSDIKGAASVQPGAFAGRNLHFGIREHAMGAI
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCHHHHHHHHH
MNGMALYGCFIPYGATFLVFSDYCRSAVRLAALMNLRLVYLFTHDSFFVGEDGPTHQPIE
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCEEECCCCCCCCCHH
QTASLRMIPGLQVIRPADGLETALAWNAALNYTNGPTALILSRQNLPVIARGSGFCTTDV
HHCCEEECCCCEEECCCCCHHHHHHHHHEEECCCCCEEEEEECCCCCEEECCCCCEEHHH
LKGGYPVASPEGAPDAVIMASGSEVHVAQEAAELLAAQGVVARVVSVPCLETFMAQPQSY
HCCCCCCCCCCCCCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
RDGLLPAGIPRIAVEAGRGESWGRLLGCDGLFIGIEHFGASAPGDVLARQFGLTPPQVAE
HCCCCCCCCCCEEEECCCCCCCCEEECCCEEEEEHHHCCCCCCHHHHHHHHCCCCHHHHH
KIAVFLKR
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]