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The map label for this gene is thiL [H]

Identifier: 118581014

GI number: 118581014

Start: 2826441

End: 2827442

Strand: Reverse

Name: thiL [H]

Synonym: Ppro_2602

Alternate gene names: 118581014

Gene position: 2827442-2826441 (Counterclockwise)

Preceding gene: 118581015

Following gene: 118581013

Centisome position: 70.54

GC content: 63.47

Gene sequence:

>1002_bases
ATGACTACTGACACGAAACTCTCCACCCTGGGCGAATTCGGCCTGATCGACCGCATCGCCGCCCATGTGGCCGGGGGCGA
GGGGGTGATCACCGGCATCGGCGACGACGCAGCCGTGACCGTCCTCACTCCCGGTATGCAGCTCTTGACCTCCACCGACA
TGCTGCTGGAGGACGTGCACTTCCGTACAACCTGGCATGATCCCCTGGCTCTGGGACGCAAGTCACTGGGGGTGAGCATC
TCCGATGTCGCCGCCATGGGGGCTATCCCGCGCTGGGCACTACTCTCTCTGGCTATCCCGGCCGGGTTTCCGCTGGAGTT
CCTGGACCGCTTCACCGAGGGGTTTCTGGCCATGGCCGGGGAGCATGGCGTGACCCTGATCGGCGGCGATACCTGCTCCT
CCAAGAACGGTCTGGTCATCTCGGTGACCATCATGGCGGAGCAGTTTCCCCACCTGATTCTGCGCCGCAGCGGAGCAAGG
GCAGGGGACGAGATCTGGGTCAGCGGCACCCTGGGGGATGCCGCCCTGGTGCTGTCGCTGCTGGAGGATGGGGCGGTGTG
CGATGAGCCGTCACTTCTGTCCCGCCTGCTGGATCCCTCGCCCCGCACCCGGGTGGGGCACGCCCTGGCCGAATCCGGCC
TGGTCAGTGCCATGATCGATGTGAGCGACGGCCTGCTGGCCGACTTTGGCCACATAGCCCAGCAGTCCGGGGTGGGGGGC
GTCCTCTACCTGGAGCGCCTCCCCATCTCCGCCGATTTCCGCCGCCGTGCCTCCCGTTTTCCCTCCTTCCCCCATCACCT
GATCCTGTCCGGCGGTGAGGACTACGAACTGGCCTTCACCGCTGCGGCGGAAAACCATGAAAAAATCGAAAGTATCGTGA
AAAACAGTGGCATTCAGGCTACGGCTGTTGGTATAGTAACGAGTTTTTCAGGGGTGGAGGTCGTCATGGAGGACGGCAGC
CGTTACATCCCCCGAAAACCAGGCTTTACCCATTCAATCTGA

Upstream 100 bases:

>100_bases
GTGTCGCGGCTCACGGTGGCTGTCACGGATGTGGACCAGTTCAAAGGCCAGGCAGGCGAATGACGCCGTGGCCGCATAGA
AGGGGAATGAACCATATACC

Downstream 100 bases:

>100_bases
CAACTCAAAAGGAACAGCGATGCAACAGACAGCGATTTCAGCGACCGAGGCACGGCTCTGCGCCGATGCGATCCGTTTTC
TCTCCGTCGATGCGGTGGAA

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MTTDTKLSTLGEFGLIDRIAAHVAGGEGVITGIGDDAAVTVLTPGMQLLTSTDMLLEDVHFRTTWHDPLALGRKSLGVSI
SDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGEHGVTLIGGDTCSSKNGLVISVTIMAEQFPHLILRRSGAR
AGDEIWVSGTLGDAALVLSLLEDGAVCDEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSDGLLADFGHIAQQSGVGG
VLYLERLPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVKNSGIQATAVGIVTSFSGVEVVMEDGS
RYIPRKPGFTHSI

Sequences:

>Translated_333_residues
MTTDTKLSTLGEFGLIDRIAAHVAGGEGVITGIGDDAAVTVLTPGMQLLTSTDMLLEDVHFRTTWHDPLALGRKSLGVSI
SDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGEHGVTLIGGDTCSSKNGLVISVTIMAEQFPHLILRRSGAR
AGDEIWVSGTLGDAALVLSLLEDGAVCDEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSDGLLADFGHIAQQSGVGG
VLYLERLPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVKNSGIQATAVGIVTSFSGVEVVMEDGS
RYIPRKPGFTHSI
>Mature_332_residues
TTDTKLSTLGEFGLIDRIAAHVAGGEGVITGIGDDAAVTVLTPGMQLLTSTDMLLEDVHFRTTWHDPLALGRKSLGVSIS
DVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAGEHGVTLIGGDTCSSKNGLVISVTIMAEQFPHLILRRSGARA
GDEIWVSGTLGDAALVLSLLEDGAVCDEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSDGLLADFGHIAQQSGVGGV
LYLERLPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVKNSGIQATAVGIVTSFSGVEVVMEDGSR
YIPRKPGFTHSI

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=328, Percent_Identity=35.3658536585366, Blast_Score=149, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35185; Mature: 35053

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTDTKLSTLGEFGLIDRIAAHVAGGEGVITGIGDDAAVTVLTPGMQLLTSTDMLLEDVH
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHH
FRTTWHDPLALGRKSLGVSISDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAG
HEECCCCHHHHCHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHEECC
EHGVTLIGGDTCSSKNGLVISVTIMAEQFPHLILRRSGARAGDEIWVSGTLGDAALVLSL
CCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHH
LEDGAVCDEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSDGLLADFGHIAQQSGVGG
HHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCHHEEEEECCCCHHHHHHHHHHHCCCCE
VLYLERLPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVKNSGIQA
EEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCE
TAVGIVTSFSGVEVVMEDGSRYIPRKPGFTHSI
EEEEEEECCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTDTKLSTLGEFGLIDRIAAHVAGGEGVITGIGDDAAVTVLTPGMQLLTSTDMLLEDVH
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHH
FRTTWHDPLALGRKSLGVSISDVAAMGAIPRWALLSLAIPAGFPLEFLDRFTEGFLAMAG
HEECCCCHHHHCHHHCCCCHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHEECC
EHGVTLIGGDTCSSKNGLVISVTIMAEQFPHLILRRSGARAGDEIWVSGTLGDAALVLSL
CCCEEEEECCCCCCCCCEEEEEEEEHHHHHHHHHHCCCCCCCCEEEEEECCCHHHHHHHH
LEDGAVCDEPSLLSRLLDPSPRTRVGHALAESGLVSAMIDVSDGLLADFGHIAQQSGVGG
HHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCHHEEEEECCCCHHHHHHHHHHHCCCCE
VLYLERLPISADFRRRASRFPSFPHHLILSGGEDYELAFTAAAENHEKIESIVKNSGIQA
EEEEEECCCCHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCHHHHHHHHHCCCCCE
TAVGIVTSFSGVEVVMEDGSRYIPRKPGFTHSI
EEEEEEECCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]