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The map label for this gene is dctB [H]

Identifier: 118580852

GI number: 118580852

Start: 2636201

End: 2638273

Strand: Reverse

Name: dctB [H]

Synonym: Ppro_2439

Alternate gene names: 118580852

Gene position: 2638273-2636201 (Counterclockwise)

Preceding gene: 118580853

Following gene: 118580851

Centisome position: 65.83

GC content: 61.89

Gene sequence:

>2073_bases
ATGCTGGACTCGGTCATCACCATCGCGGCCATTGTTGCCCTGCTGTTTGCCGCGGGATACGCCCTGCACCGGGAACGCTC
CCGCGCCGGCCTGTTTCTCTGCGGCGCGCTGCTGCTGACCGCCCTTTTGGAGCTGTTCGACCTCTTGTCCCTCAGCCTGC
CTCAGGCTGCCGTGCCGTGGAAATGGTTCTCGCTTGTGGCCGAATCCCTGCTCCCCTTCTTCTGGATCATGTGCAGCCTG
ACCTACGCCCGTCAGGCCGCCCCCTGGAGGTTCGGCCCGCTGCTCAAGGGAGTGATCGCCCTTTCCCTGCTCTTCTGTCT
GCTCCCCTTTGCCGTTCCCCTGGACTCATTCTTCTACGCCCCTGATTTCCCGCTGGAGCGGCTGCTCTTCCTGGGGAATG
TCGGCTACTTCTACTACCTGGGGCTCATGGCTGCCCTGATATTCGCCCTGGTCAACTTTGAGACCACCCTGGCCAATGCC
TCTCCCGAGTCGCTGGACAGGGTCAAGTTCGAGATCATCGGCCTGGGCGCCTTCCTGGGGGTGCTGATCTTCTACTTCAG
CCAGGCCCTGGTGTACCGCAGCCTGAACATGAACTACCTGCAGCTGCGCTCGCTGCTCTACCTGGTTGGCCTGGGGCTGA
TGGCCTATTCCCTGCTGTTCCGCAGGGGAGGGGTGCGTATCCAGGTGTCCCGCCAGGCGGCTTTCAAGTCCTTCGTGCTG
GTGGCGGTCGGGCTGTACCTGATCATGATCGGCCTTTTGGGGGAGGGGATGCAGTACTTCGGCGTTTCCTTCCAGCGCAC
GGTGACCGTCTCCTTCGCCTTTATCGCCGGCATCGTGCTGCTGCTGCTCCTTCTCTCCCAGCGCTTCCAGCGCGAGGTCA
AGGTCGCGTTGCACAAGAACTTCTACCAGCACAAGCACGACTACCGCACCCAGTGGCTGCGCTTCACCGAGCAGCTCGCC
ACCTCCCGTTCCTCCGACGAACTCTTGCAGCGCATCCTGTCCGCCTATTGCGACGTGTTCGGCATGGCAGGGGCGGCGCT
GTTCCTCCTGGAGCAGAACCGCGGCGGGTACGGCATGACGGCGACCCACAACATGCAGCCCATGGGGGCACTGATCAAGC
CGGATAATTCCCTGGTCAGGTTCATGGTCGAGCGCACCTGGGTGGTCAACGTCAGGGACGATACCCCCGAAGTCATGGAG
GAGAACGGCGCCTTCTTCCGCGACAACCAGATATCCTTCGTCATCCCGCTCTTTGGCGCCGAGCGCATGGAGGGGTTCAT
CGTCCTGGGGCGGGTGATCAAGGAAGACGAGGTGTACATCTACGAAGATTATGACCTGATGAAGACCATCGCCCGCCAGG
CCTCCCAGGCGATCCTGCACCAGCGCCTCTCGGAGCAGCTCTCCCAGGCGCGGGAGGTGGAGGCCATCGGCAATATCGCC
GCCTTCGTGGCCCACGACCTGAAGAACCTGGTCAGCAACCTGTCGCTGATCGTGGAGAATGCCGGCCGCTTCATCCAGAA
TCCCGACTTCCAGCAGGACATGCTGGTCTCCCTGGGCAATACCGTCACCAAGATGCAGCACCTGATCGGCAGGCTCAGGA
ACCTGGGGGAGCGGGACCATTTCACGGCCAAACCGGTGAATCTGCTGGAACTGGCCGAGAAGACCGCCCGTCTGGCCAGT
GGCTCTGCCGTTACGGTGGAGGGGAGCGCCGAGACGGTGGTCGTGGATGAAAACGAGATGCAGAACGTGATCATGAACCT
GCTGATGAACGCCATCGAGGCATCCGGGCCGGACAGGGGCGTGCGGATCCAGGTCGGCAACCTGGGCAATCCCTATCTGG
CGGTGCACGATCAGGGGCATGGCATGTCGGCTGATTTCATGCGCAGGGAGCTGTTCAAGCCCTTCAAGACCACCAAGAAG
AAGGGGCTGGGGATCGGACTGTACCAGTGCAAGCAGACAGTGGAGTCTTTTGGCGGTAGAATCGAAGTGGACAGTGAAGA
GGGTGTGGGGACGACATTTACGATCTGGTTCAGCCAGGGGGGCGAAGGCGGTACCCCGGTCGGCCATTGCTGA

Upstream 100 bases:

>100_bases
GACGCCTCTCTATCGTGGTACGTGGATAACCTCTGCCCCACGGTGGAGGGGAACTTGCCCGCTGCCGGGTCACGGGGCCT
GGAGCCCGTGGGGAACTGAC

Downstream 100 bases:

>100_bases
CGAGGGACAATGCACATGGTAAAGATACTGATAATCGATGACGATCCCGATATCCGCCAGCAGCTGAAGTGGGGCTTGAG
CGACGAGTACAGCGTCGTGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 690; Mature: 690

Protein sequence:

>690_residues
MLDSVITIAAIVALLFAAGYALHRERSRAGLFLCGALLLTALLELFDLLSLSLPQAAVPWKWFSLVAESLLPFFWIMCSL
TYARQAAPWRFGPLLKGVIALSLLFCLLPFAVPLDSFFYAPDFPLERLLFLGNVGYFYYLGLMAALIFALVNFETTLANA
SPESLDRVKFEIIGLGAFLGVLIFYFSQALVYRSLNMNYLQLRSLLYLVGLGLMAYSLLFRRGGVRIQVSRQAAFKSFVL
VAVGLYLIMIGLLGEGMQYFGVSFQRTVTVSFAFIAGIVLLLLLLSQRFQREVKVALHKNFYQHKHDYRTQWLRFTEQLA
TSRSSDELLQRILSAYCDVFGMAGAALFLLEQNRGGYGMTATHNMQPMGALIKPDNSLVRFMVERTWVVNVRDDTPEVME
ENGAFFRDNQISFVIPLFGAERMEGFIVLGRVIKEDEVYIYEDYDLMKTIARQASQAILHQRLSEQLSQAREVEAIGNIA
AFVAHDLKNLVSNLSLIVENAGRFIQNPDFQQDMLVSLGNTVTKMQHLIGRLRNLGERDHFTAKPVNLLELAEKTARLAS
GSAVTVEGSAETVVVDENEMQNVIMNLLMNAIEASGPDRGVRIQVGNLGNPYLAVHDQGHGMSADFMRRELFKPFKTTKK
KGLGIGLYQCKQTVESFGGRIEVDSEEGVGTTFTIWFSQGGEGGTPVGHC

Sequences:

>Translated_690_residues
MLDSVITIAAIVALLFAAGYALHRERSRAGLFLCGALLLTALLELFDLLSLSLPQAAVPWKWFSLVAESLLPFFWIMCSL
TYARQAAPWRFGPLLKGVIALSLLFCLLPFAVPLDSFFYAPDFPLERLLFLGNVGYFYYLGLMAALIFALVNFETTLANA
SPESLDRVKFEIIGLGAFLGVLIFYFSQALVYRSLNMNYLQLRSLLYLVGLGLMAYSLLFRRGGVRIQVSRQAAFKSFVL
VAVGLYLIMIGLLGEGMQYFGVSFQRTVTVSFAFIAGIVLLLLLLSQRFQREVKVALHKNFYQHKHDYRTQWLRFTEQLA
TSRSSDELLQRILSAYCDVFGMAGAALFLLEQNRGGYGMTATHNMQPMGALIKPDNSLVRFMVERTWVVNVRDDTPEVME
ENGAFFRDNQISFVIPLFGAERMEGFIVLGRVIKEDEVYIYEDYDLMKTIARQASQAILHQRLSEQLSQAREVEAIGNIA
AFVAHDLKNLVSNLSLIVENAGRFIQNPDFQQDMLVSLGNTVTKMQHLIGRLRNLGERDHFTAKPVNLLELAEKTARLAS
GSAVTVEGSAETVVVDENEMQNVIMNLLMNAIEASGPDRGVRIQVGNLGNPYLAVHDQGHGMSADFMRRELFKPFKTTKK
KGLGIGLYQCKQTVESFGGRIEVDSEEGVGTTFTIWFSQGGEGGTPVGHC
>Mature_690_residues
MLDSVITIAAIVALLFAAGYALHRERSRAGLFLCGALLLTALLELFDLLSLSLPQAAVPWKWFSLVAESLLPFFWIMCSL
TYARQAAPWRFGPLLKGVIALSLLFCLLPFAVPLDSFFYAPDFPLERLLFLGNVGYFYYLGLMAALIFALVNFETTLANA
SPESLDRVKFEIIGLGAFLGVLIFYFSQALVYRSLNMNYLQLRSLLYLVGLGLMAYSLLFRRGGVRIQVSRQAAFKSFVL
VAVGLYLIMIGLLGEGMQYFGVSFQRTVTVSFAFIAGIVLLLLLLSQRFQREVKVALHKNFYQHKHDYRTQWLRFTEQLA
TSRSSDELLQRILSAYCDVFGMAGAALFLLEQNRGGYGMTATHNMQPMGALIKPDNSLVRFMVERTWVVNVRDDTPEVME
ENGAFFRDNQISFVIPLFGAERMEGFIVLGRVIKEDEVYIYEDYDLMKTIARQASQAILHQRLSEQLSQAREVEAIGNIA
AFVAHDLKNLVSNLSLIVENAGRFIQNPDFQQDMLVSLGNTVTKMQHLIGRLRNLGERDHFTAKPVNLLELAEKTARLAS
GSAVTVEGSAETVVVDENEMQNVIMNLLMNAIEASGPDRGVRIQVGNLGNPYLAVHDQGHGMSADFMRRELFKPFKTTKK
KGLGIGLYQCKQTVESFGGRIEVDSEEGVGTTFTIWFSQGGEGGTPVGHC

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=28.1938325991189, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=24.6753246753247, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77036; Mature: 77036

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDSVITIAAIVALLFAAGYALHRERSRAGLFLCGALLLTALLELFDLLSLSLPQAAVPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
KWFSLVAESLLPFFWIMCSLTYARQAAPWRFGPLLKGVIALSLLFCLLPFAVPLDSFFYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDFPLERLLFLGNVGYFYYLGLMAALIFALVNFETTLANASPESLDRVKFEIIGLGAFLG
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEHHHHHH
VLIFYFSQALVYRSLNMNYLQLRSLLYLVGLGLMAYSLLFRRGGVRIQVSRQAAFKSFVL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
VAVGLYLIMIGLLGEGMQYFGVSFQRTVTVSFAFIAGIVLLLLLLSQRFQREVKVALHKN
HHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYQHKHDYRTQWLRFTEQLATSRSSDELLQRILSAYCDVFGMAGAALFLLEQNRGGYGMT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCC
ATHNMQPMGALIKPDNSLVRFMVERTWVVNVRDDTPEVMEENGAFFRDNQISFVIPLFGA
EECCCCCCCCEECCCHHHHHHHHHHEEEEEECCCCHHHHHCCCCEEECCCEEEEEECCCC
ERMEGFIVLGRVIKEDEVYIYEDYDLMKTIARQASQAILHQRLSEQLSQAREVEAIGNIA
HHHCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVAHDLKNLVSNLSLIVENAGRFIQNPDFQQDMLVSLGNTVTKMQHLIGRLRNLGERDH
HHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FTAKPVNLLELAEKTARLASGSAVTVEGSAETVVVDENEMQNVIMNLLMNAIEASGPDRG
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCC
VRIQVGNLGNPYLAVHDQGHGMSADFMRRELFKPFKTTKKKGLGIGLYQCKQTVESFGGR
EEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCE
IEVDSEEGVGTTFTIWFSQGGEGGTPVGHC
EEECCCCCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MLDSVITIAAIVALLFAAGYALHRERSRAGLFLCGALLLTALLELFDLLSLSLPQAAVPW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
KWFSLVAESLLPFFWIMCSLTYARQAAPWRFGPLLKGVIALSLLFCLLPFAVPLDSFFYA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PDFPLERLLFLGNVGYFYYLGLMAALIFALVNFETTLANASPESLDRVKFEIIGLGAFLG
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHEEHHHHHH
VLIFYFSQALVYRSLNMNYLQLRSLLYLVGLGLMAYSLLFRRGGVRIQVSRQAAFKSFVL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHH
VAVGLYLIMIGLLGEGMQYFGVSFQRTVTVSFAFIAGIVLLLLLLSQRFQREVKVALHKN
HHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FYQHKHDYRTQWLRFTEQLATSRSSDELLQRILSAYCDVFGMAGAALFLLEQNRGGYGMT
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCC
ATHNMQPMGALIKPDNSLVRFMVERTWVVNVRDDTPEVMEENGAFFRDNQISFVIPLFGA
EECCCCCCCCEECCCHHHHHHHHHHEEEEEECCCCHHHHHCCCCEEECCCEEEEEECCCC
ERMEGFIVLGRVIKEDEVYIYEDYDLMKTIARQASQAILHQRLSEQLSQAREVEAIGNIA
HHHCHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFVAHDLKNLVSNLSLIVENAGRFIQNPDFQQDMLVSLGNTVTKMQHLIGRLRNLGERDH
HHHHHHHHHHHHHHHHHHHHHCHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
FTAKPVNLLELAEKTARLASGSAVTVEGSAETVVVDENEMQNVIMNLLMNAIEASGPDRG
CCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCC
VRIQVGNLGNPYLAVHDQGHGMSADFMRRELFKPFKTTKKKGLGIGLYQCKQTVESFGGR
EEEEECCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCE
IEVDSEEGVGTTFTIWFSQGGEGGTPVGHC
EEECCCCCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431; 2551890; 2695394 [H]