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The map label for this gene is yggV [C]

Identifier: 118580725

GI number: 118580725

Start: 2493043

End: 2493666

Strand: Reverse

Name: yggV [C]

Synonym: Ppro_2310

Alternate gene names: 118580725

Gene position: 2493666-2493043 (Counterclockwise)

Preceding gene: 118580726

Following gene: 118580724

Centisome position: 62.22

GC content: 64.74

Gene sequence:

>624_bases
ATGAAAGAACTGGTGGTGGCCACTCGCAATCGCGGAAAACTGAACGAGATACGGGCGTTCCTGTCGGGTGTCGTGGAACG
GGTCAGTTGCGCTTCCGACTTCGAGGGGTTCCCCGAGACCGTGGAAGATGGCGCAACGTTTGAACAGAACGCCCTCAAGA
AGGCTCGGGAGGCGATGCGCTTCACCGGGCTGCCTGCCCTGGCTGACGATTCCGGCCTGGTGGTGGATGCTCTTGACGGG
CGTCCCGGCGTGCTCTCCGCCCGCTTCAGCGGCGAGGAGGGCGGTGACGGAGCCAACAACCGCAAACTGCTGGAAGAGAT
GGGCGGGATGCCTCCCCAGGGGAGAGGCGCCGCCTTTGTCTGCGCCCTGGCGTATGTGACACCTGATGGCGGGGAGCGGC
TCTTCTTCGGCAGGGTCGGGGGGCGCATTCTGGAGCAGGAGCGGGGAGAGGGGGGCTTCGGTTACGACCCGCTCTTCCTG
GTGGACGGGTTCCAGCGCACCATGGCGGAACTGGGCATGGAAGAGAAGAACGGCATCAGCCATCGTGGAGAGGCGCTGCG
GGGGTTTCGGGAGTACCTGTGTGGCTGCCCGGGTTTCTGTGGCGCTGGAGAGGGACAGGAGTAA

Upstream 100 bases:

>100_bases
AGGTGGAGCCGTTCACCCTTGAGCAGATGGACGCCATGCGCAGTCTGGCCATGGACGGCATTCAGTGTCTGTTCGATCTT
CAGCGGGAGGCGCTCAAGGG

Downstream 100 bases:

>100_bases
ACGTCGATGAAAAGAGAGAAACAGAGTAGCGGTTCAAGGCGTAAGGGGGACGGAACGGTAGGTCCCGCGGGCGGCAAGCC
GGGCGGAGAGCGCCCCCTCC

Product: RdgB/HAM1 family non-canonical purine NTP pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MKELVVATRNRGKLNEIRAFLSGVVERVSCASDFEGFPETVEDGATFEQNALKKAREAMRFTGLPALADDSGLVVDALDG
RPGVLSARFSGEEGGDGANNRKLLEEMGGMPPQGRGAAFVCALAYVTPDGGERLFFGRVGGRILEQERGEGGFGYDPLFL
VDGFQRTMAELGMEEKNGISHRGEALRGFREYLCGCPGFCGAGEGQE

Sequences:

>Translated_207_residues
MKELVVATRNRGKLNEIRAFLSGVVERVSCASDFEGFPETVEDGATFEQNALKKAREAMRFTGLPALADDSGLVVDALDG
RPGVLSARFSGEEGGDGANNRKLLEEMGGMPPQGRGAAFVCALAYVTPDGGERLFFGRVGGRILEQERGEGGFGYDPLFL
VDGFQRTMAELGMEEKNGISHRGEALRGFREYLCGCPGFCGAGEGQE
>Mature_207_residues
MKELVVATRNRGKLNEIRAFLSGVVERVSCASDFEGFPETVEDGATFEQNALKKAREAMRFTGLPALADDSGLVVDALDG
RPGVLSARFSGEEGGDGANNRKLLEEMGGMPPQGRGAAFVCALAYVTPDGGERLFFGRVGGRILEQERGEGGFGYDPLFL
VDGFQRTMAELGMEEKNGISHRGEALRGFREYLCGCPGFCGAGEGQE

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=200, Percent_Identity=31.5, Blast_Score=84, Evalue=9e-17,
Organism=Homo sapiens, GI31657144, Length=148, Percent_Identity=35.1351351351351, Blast_Score=79, Evalue=4e-15,
Organism=Escherichia coli, GI1789324, Length=195, Percent_Identity=44.6153846153846, Blast_Score=150, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17556833, Length=196, Percent_Identity=31.6326530612245, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322529, Length=203, Percent_Identity=29.5566502463054, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19920712, Length=192, Percent_Identity=30.7291666666667, Blast_Score=84, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 22153; Mature: 22153

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKELVVATRNRGKLNEIRAFLSGVVERVSCASDFEGFPETVEDGATFEQNALKKAREAMR
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHH
FTGLPALADDSGLVVDALDGRPGVLSARFSGEEGGDGANNRKLLEEMGGMPPQGRGAAFV
HCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCEEE
CALAYVTPDGGERLFFGRVGGRILEQERGEGGFGYDPLFLVDGFQRTMAELGMEEKNGIS
EEEEEECCCCCCEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
HRGEALRGFREYLCGCPGFCGAGEGQE
HHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKELVVATRNRGKLNEIRAFLSGVVERVSCASDFEGFPETVEDGATFEQNALKKAREAMR
CCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHH
FTGLPALADDSGLVVDALDGRPGVLSARFSGEEGGDGANNRKLLEEMGGMPPQGRGAAFV
HCCCCCCCCCCCCEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCCCEEE
CALAYVTPDGGERLFFGRVGGRILEQERGEGGFGYDPLFLVDGFQRTMAELGMEEKNGIS
EEEEEECCCCCCEEEEECCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCC
HRGEALRGFREYLCGCPGFCGAGEGQE
HHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA