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The map label for this gene is baeR [H]

Identifier: 118580643

GI number: 118580643

Start: 2403443

End: 2404111

Strand: Direct

Name: baeR [H]

Synonym: Ppro_2228

Alternate gene names: 118580643

Gene position: 2403443-2404111 (Clockwise)

Preceding gene: 118580642

Following gene: 118580645

Centisome position: 59.97

GC content: 60.24

Gene sequence:

>669_bases
ATGAATGGAAGCGTACTGATTGTTGAGGATGAGGAGAAGCTGTCGTCGCTTCTGCACGATTACCTGTCGCAGTCCGGCTT
CGAGACGCACCGCTTGAGAAACGGCCTGGACGTGGTTCCCTGGGTGCGCGAACGGAACCCGGACCTGATCCTGCTCGACC
TGATGCTGCCGGGGCGGGACGGCCTGGAGATATGCAAGGAGATCCGCTCCTTTTCATCGGTGCCGATCATCATGACCACG
GCCCGGGTGGAGGAGATCGACCGACTGCTCGGCCTGGAACTGGGGGCCGACGATTACATCTGCAAACCGTTCAGTCCCCG
TGAGGTGGTTGCGCGGGTCAAGGCGGTCCTGCGCAGAACCGATGGGGGAACGACCATCAAGGCCTCCGGACTGACTTTGG
ATGAATTGCGCCTGCGGGCCGTCCTGAACGACCGGGACCTGGAACTGACCGCGGTGGAGTTCAAGCTGCTGCAGTTTTTG
GCCGCCAACCCCGGGCGCATCTACAGTCGCCAGCAGTTGATGGATCGCATCTATCCTGACGAGCGCATCGTTTCCGACCG
GACCATCGACAGCCACATCAAAAAGCTGCGCCGCAAAATCGCCGTTGCCACCCCCGATGAGGAGCTGATCCATTCCGTGT
ACGGTGTGGGTTACAAGTTTGAACGCTGA

Upstream 100 bases:

>100_bases
CAACATCGTTGAAGCACACGCCGGATCGATAACAGCCCGGCCATCTTCCCTGGGCGGATTATGGATACGGATCGAGATTC
CGAGGAAAGGAACCAACTAG

Downstream 100 bases:

>100_bases
GGTGATACCACGGAGAGAAGAAAAACGCCGCTCACCCCAGACGGGAAAAAAAGCGGGATGACCAGAAATAATGTTTTACA
AGCACCTGAATATATTCAGC

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MNGSVLIVEDEEKLSSLLHDYLSQSGFETHRLRNGLDVVPWVRERNPDLILLDLMLPGRDGLEICKEIRSFSSVPIIMTT
ARVEEIDRLLGLELGADDYICKPFSPREVVARVKAVLRRTDGGTTIKASGLTLDELRLRAVLNDRDLELTAVEFKLLQFL
AANPGRIYSRQQLMDRIYPDERIVSDRTIDSHIKKLRRKIAVATPDEELIHSVYGVGYKFER

Sequences:

>Translated_222_residues
MNGSVLIVEDEEKLSSLLHDYLSQSGFETHRLRNGLDVVPWVRERNPDLILLDLMLPGRDGLEICKEIRSFSSVPIIMTT
ARVEEIDRLLGLELGADDYICKPFSPREVVARVKAVLRRTDGGTTIKASGLTLDELRLRAVLNDRDLELTAVEFKLLQFL
AANPGRIYSRQQLMDRIYPDERIVSDRTIDSHIKKLRRKIAVATPDEELIHSVYGVGYKFER
>Mature_222_residues
MNGSVLIVEDEEKLSSLLHDYLSQSGFETHRLRNGLDVVPWVRERNPDLILLDLMLPGRDGLEICKEIRSFSSVPIIMTT
ARVEEIDRLLGLELGADDYICKPFSPREVVARVKAVLRRTDGGTTIKASGLTLDELRLRAVLNDRDLELTAVEFKLLQFL
AANPGRIYSRQQLMDRIYPDERIVSDRTIDSHIKKLRRKIAVATPDEELIHSVYGVGYKFER

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=54.7511312217195, Blast_Score=245, Evalue=2e-66,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=42.7927927927928, Blast_Score=177, Evalue=4e-46,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=41.5929203539823, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=38.4279475982533, Blast_Score=154, Evalue=3e-39,
Organism=Escherichia coli, GI2367329, Length=224, Percent_Identity=37.9464285714286, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.4561403508772, Blast_Score=130, Evalue=6e-32,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35.4545454545455, Blast_Score=127, Evalue=8e-31,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=34.6666666666667, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI87082012, Length=217, Percent_Identity=34.5622119815668, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=34.1013824884793, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=33.6244541484716, Blast_Score=118, Evalue=4e-28,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=36.1607142857143, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=30.1724137931034, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=32.7188940092166, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1788550, Length=101, Percent_Identity=36.6336633663366, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1790299, Length=113, Percent_Identity=31.858407079646, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25331; Mature: 25331

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGSVLIVEDEEKLSSLLHDYLSQSGFETHRLRNGLDVVPWVRERNPDLILLDLMLPGRD
CCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHCCCCCEEEEEEECCCCC
GLEICKEIRSFSSVPIIMTTARVEEIDRLLGLELGADDYICKPFSPREVVARVKAVLRRT
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHC
DGGTTIKASGLTLDELRLRAVLNDRDLELTAVEFKLLQFLAANPGRIYSRQQLMDRIYPD
CCCCEEEECCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
ERIVSDRTIDSHIKKLRRKIAVATPDEELIHSVYGVGYKFER
CHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEECC
>Mature Secondary Structure
MNGSVLIVEDEEKLSSLLHDYLSQSGFETHRLRNGLDVVPWVRERNPDLILLDLMLPGRD
CCCCEEEEECHHHHHHHHHHHHHHCCCHHHHHHCCCCCCCHHHCCCCCEEEEEEECCCCC
GLEICKEIRSFSSVPIIMTTARVEEIDRLLGLELGADDYICKPFSPREVVARVKAVLRRT
HHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHC
DGGTTIKASGLTLDELRLRAVLNDRDLELTAVEFKLLQFLAANPGRIYSRQQLMDRIYPD
CCCCEEEECCCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
ERIVSDRTIDSHIKKLRRKIAVATPDEELIHSVYGVGYKFER
CHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]