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The map label for this gene is baeS [H]

Identifier: 118580642

GI number: 118580642

Start: 2401961

End: 2403442

Strand: Direct

Name: baeS [H]

Synonym: Ppro_2227

Alternate gene names: 118580642

Gene position: 2401961-2403442 (Clockwise)

Preceding gene: 118580627

Following gene: 118580643

Centisome position: 59.93

GC content: 63.56

Gene sequence:

>1482_bases
ATGAGGCTCGGCGTAACCCACAAACTGTTTCTTGCGATCCTGACGGCGGCCGGACTCGCGGTGATCTGCTCCGCGCTCAT
CATGCAGTGGAGGCTCAACCGGGGGTTTAACAACTACCTGAATTCAATCGAAAAAGCTGGGATTTCCCGCCTGGCCGCCA
CACTGGAGAAGAGCTACGGCACGGAGCGGAGCTGGGGGTCCCTGGCCAGGAATCATGAGCGCTGGCGACAGCTGGTTATC
TCCTCGTTTCCCATGATCCCCCTGGAGGAGATTCCCCCCGGGGATCAGATGCCGCCGCCTGCAGGCATGCCTCCCGGCGC
CCCGGAAGAACACACCGACCAGAACAGTGCTCGCCCCCACGGGCTGCTGCCGCCTCCCATGGCCCGTCGTTTCGACCAGC
GCCTGTACCTCCTGGATGCGGACAAAAGAGTCGTGGTCAGCAGGGTCATGGCTCCGGACGCAAGCAGGGCGACCCCCCTG
CGATACCGGGGAGCGGTGGTGGGCTACCTGGGGATCATGCCGCGCACACGCCCATTCGCCGACGAGCCCCAGCGGCGCTT
CATCAGGGACCAGGAACAGGCCCTGACCCTGACGGCTGGGGTCGTGGTACTCCTGGCAGCCATCCTCTCCCTACTCATGG
CCAGACGACTGGTTCGGCCGCTGCGGGAACTGGCCGCGGCAACCCATCGTCTGTCGTCCGGGGTATTCTCCGTCCGGGTG
CCGATCAGTTCTCGAGACGAACTGGGGGAGCTTGCCGGCGACTTCAACTCCCTGGCGCTCACCCTGGAGAAGAACGAGGA
GAGCCGGCGCCAATGGGTCGCCGACATCTCCCATGAACTGCGCACCCCCCTGGCCATCCTGCGGGGAGAAATCGAAGCGA
TCCAGGACGGCATCCGCCAGCCGACACCGCAGACGATCCAGTCTCTCCATGGGGAGGTGCTGCACCTGGGGCGACTGGTT
GACGACCTGTACCAGCTCTCCATGTCCGATGTGGGTGCGCTGACCTATCGCAAGAGCGAACTCGACCTGGGGGATCTGCT
CTCCGAGACCGTTGCAGCGTTCCGCCCCGAGTTCTCCTCCAAGGGGATAACCATCGTGGAGAGCATCAACGACACAGCAG
GCACCACCGTTTTCGGCGACCCGGAACGCCTGCGCCAGCTCTTCACGAACCTGCTGAAAAACTCCCTCAAATATACCGAT
GCCGGTGGCACGCTTATCGTGCGCCTGCAGGCGAACGGGGACATGGCAACGGTGGATTTCCAGGATTCCCCCCCCGCCGT
TCCGCCGGCGGAAATGGAGCGACTGTTCGAACGGCTCTACCGGGTGGATTCCTCCCGCAACCGCTCCACAGGTGGGGCCG
GCCTCGGCCTGGCAATCTGCCGCAACATCGTTGAAGCACACGCCGGATCGATAACAGCCCGGCCATCTTCCCTGGGCGGA
TTATGGATACGGATCGAGATTCCGAGGAAAGGAACCAACTAG

Upstream 100 bases:

>100_bases
GACAAAATGTGAAAAGTTCACCCCGGACAACAGAGCCCATGTCCCTATACATCCAGCTGTGATACAACTACGCCATTCTT
TAGCGAAGGAACGACTCGCC

Downstream 100 bases:

>100_bases
ATGAATGGAAGCGTACTGATTGTTGAGGATGAGGAGAAGCTGTCGTCGCTTCTGCACGATTACCTGTCGCAGTCCGGCTT
CGAGACGCACCGCTTGAGAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MRLGVTHKLFLAILTAAGLAVICSALIMQWRLNRGFNNYLNSIEKAGISRLAATLEKSYGTERSWGSLARNHERWRQLVI
SSFPMIPLEEIPPGDQMPPPAGMPPGAPEEHTDQNSARPHGLLPPPMARRFDQRLYLLDADKRVVVSRVMAPDASRATPL
RYRGAVVGYLGIMPRTRPFADEPQRRFIRDQEQALTLTAGVVVLLAAILSLLMARRLVRPLRELAAATHRLSSGVFSVRV
PISSRDELGELAGDFNSLALTLEKNEESRRQWVADISHELRTPLAILRGEIEAIQDGIRQPTPQTIQSLHGEVLHLGRLV
DDLYQLSMSDVGALTYRKSELDLGDLLSETVAAFRPEFSSKGITIVESINDTAGTTVFGDPERLRQLFTNLLKNSLKYTD
AGGTLIVRLQANGDMATVDFQDSPPAVPPAEMERLFERLYRVDSSRNRSTGGAGLGLAICRNIVEAHAGSITARPSSLGG
LWIRIEIPRKGTN

Sequences:

>Translated_493_residues
MRLGVTHKLFLAILTAAGLAVICSALIMQWRLNRGFNNYLNSIEKAGISRLAATLEKSYGTERSWGSLARNHERWRQLVI
SSFPMIPLEEIPPGDQMPPPAGMPPGAPEEHTDQNSARPHGLLPPPMARRFDQRLYLLDADKRVVVSRVMAPDASRATPL
RYRGAVVGYLGIMPRTRPFADEPQRRFIRDQEQALTLTAGVVVLLAAILSLLMARRLVRPLRELAAATHRLSSGVFSVRV
PISSRDELGELAGDFNSLALTLEKNEESRRQWVADISHELRTPLAILRGEIEAIQDGIRQPTPQTIQSLHGEVLHLGRLV
DDLYQLSMSDVGALTYRKSELDLGDLLSETVAAFRPEFSSKGITIVESINDTAGTTVFGDPERLRQLFTNLLKNSLKYTD
AGGTLIVRLQANGDMATVDFQDSPPAVPPAEMERLFERLYRVDSSRNRSTGGAGLGLAICRNIVEAHAGSITARPSSLGG
LWIRIEIPRKGTN
>Mature_493_residues
MRLGVTHKLFLAILTAAGLAVICSALIMQWRLNRGFNNYLNSIEKAGISRLAATLEKSYGTERSWGSLARNHERWRQLVI
SSFPMIPLEEIPPGDQMPPPAGMPPGAPEEHTDQNSARPHGLLPPPMARRFDQRLYLLDADKRVVVSRVMAPDASRATPL
RYRGAVVGYLGIMPRTRPFADEPQRRFIRDQEQALTLTAGVVVLLAAILSLLMARRLVRPLRELAAATHRLSSGVFSVRV
PISSRDELGELAGDFNSLALTLEKNEESRRQWVADISHELRTPLAILRGEIEAIQDGIRQPTPQTIQSLHGEVLHLGRLV
DDLYQLSMSDVGALTYRKSELDLGDLLSETVAAFRPEFSSKGITIVESINDTAGTTVFGDPERLRQLFTNLLKNSLKYTD
AGGTLIVRLQANGDMATVDFQDSPPAVPPAEMERLFERLYRVDSSRNRSTGGAGLGLAICRNIVEAHAGSITARPSSLGG
LWIRIEIPRKGTN

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=489, Percent_Identity=41.9222903885481, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI1786783, Length=301, Percent_Identity=29.9003322259136, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI145693157, Length=264, Percent_Identity=26.1363636363636, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1786912, Length=231, Percent_Identity=29.004329004329, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790346, Length=316, Percent_Identity=28.7974683544304, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1787894, Length=261, Percent_Identity=31.4176245210728, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=30.4347826086957, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1789149, Length=393, Percent_Identity=23.4096692111959, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI87081816, Length=333, Percent_Identity=25.5255255255255, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87082128, Length=322, Percent_Identity=24.8447204968944, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1788713, Length=251, Percent_Identity=25.8964143426295, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788279, Length=295, Percent_Identity=25.4237288135593, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=27.8026905829596, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790861, Length=270, Percent_Identity=25.9259259259259, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787374, Length=267, Percent_Identity=25.8426966292135, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790551, Length=314, Percent_Identity=25.1592356687898, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1790436, Length=304, Percent_Identity=25.6578947368421, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789808, Length=292, Percent_Identity=25.6849315068493, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=312, Percent_Identity=26.6025641025641, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 54380; Mature: 54380

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLGVTHKLFLAILTAAGLAVICSALIMQWRLNRGFNNYLNSIEKAGISRLAATLEKSYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
TERSWGSLARNHERWRQLVISSFPMIPLEEIPPGDQMPPPAGMPPGAPEEHTDQNSARPH
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLLPPPMARRFDQRLYLLDADKRVVVSRVMAPDASRATPLRYRGAVVGYLGIMPRTRPFA
CCCCCHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
DEPQRRFIRDQEQALTLTAGVVVLLAAILSLLMARRLVRPLRELAAATHRLSSGVFSVRV
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
PISSRDELGELAGDFNSLALTLEKNEESRRQWVADISHELRTPLAILRGEIEAIQDGIRQ
CCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTPQTIQSLHGEVLHLGRLVDDLYQLSMSDVGALTYRKSELDLGDLLSETVAAFRPEFSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCC
KGITIVESINDTAGTTVFGDPERLRQLFTNLLKNSLKYTDAGGTLIVRLQANGDMATVDF
CCEEEEECCCCCCCCCEECCHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCEEEEEC
QDSPPAVPPAEMERLFERLYRVDSSRNRSTGGAGLGLAICRNIVEAHAGSITARPSSLGG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCC
LWIRIEIPRKGTN
EEEEEEECCCCCC
>Mature Secondary Structure
MRLGVTHKLFLAILTAAGLAVICSALIMQWRLNRGFNNYLNSIEKAGISRLAATLEKSYG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCC
TERSWGSLARNHERWRQLVISSFPMIPLEEIPPGDQMPPPAGMPPGAPEEHTDQNSARPH
CCCHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GLLPPPMARRFDQRLYLLDADKRVVVSRVMAPDASRATPLRYRGAVVGYLGIMPRTRPFA
CCCCCHHHHHHCCEEEEECCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCC
DEPQRRFIRDQEQALTLTAGVVVLLAAILSLLMARRLVRPLRELAAATHRLSSGVFSVRV
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEE
PISSRDELGELAGDFNSLALTLEKNEESRRQWVADISHELRTPLAILRGEIEAIQDGIRQ
CCCCHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTPQTIQSLHGEVLHLGRLVDDLYQLSMSDVGALTYRKSELDLGDLLSETVAAFRPEFSS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHHHHHHCCCCCC
KGITIVESINDTAGTTVFGDPERLRQLFTNLLKNSLKYTDAGGTLIVRLQANGDMATVDF
CCEEEEECCCCCCCCCEECCHHHHHHHHHHHHHHCCCEECCCCEEEEEEECCCCEEEEEC
QDSPPAVPPAEMERLFERLYRVDSSRNRSTGGAGLGLAICRNIVEAHAGSITARPSSLGG
CCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEECCCCCCC
LWIRIEIPRKGTN
EEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]