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The map label for this gene is ihfA [H]

Identifier: 118580291

GI number: 118580291

Start: 2013360

End: 2013644

Strand: Reverse

Name: ihfA [H]

Synonym: Ppro_1872

Alternate gene names: 118580291

Gene position: 2013644-2013360 (Counterclockwise)

Preceding gene: 118580292

Following gene: 118580290

Centisome position: 50.24

GC content: 45.61

Gene sequence:

>285_bases
ATGACAAAAGCTGACATTTTTGAAAAAGTATCCTCGAACCTAGGCTACACAAAAAAAGAATCCGCTGAACTGGTAGAAGC
AGTGTTCTCCTTAATCAAAAGTACACTGGAATCCGGTGAAAAAATTAAGATAGCCGGTTTTGGGAACTTTGAGGTCAAGC
AGAAGGCAGACCGTCGTGGTCGCAACCCGCAGAACGGTGAGACAATCACCATCGAGGCACGTCGTATCCTTACCTTTAAG
CCGAGCGGTGTCCTTAAAACAGCGATTAACGGTGCAAAGCAGTGA

Upstream 100 bases:

>100_bases
GATTTAGGCATTACGCCCGAGCTAAAATGCATCAAATTCGAGTATGATGTTGTCTAAACATAAATATTGTTGCACATAAA
TGATTATTTGGAAGAATTAA

Downstream 100 bases:

>100_bases
TACGTCCTTATCTATTGTCAATTACAGCATTATTGCTGAGTGCCGGAATTGCGTTCGCTGCTGACACCTCGTGCCCTGAA
CATTTTACCGGTGGAAAAGC

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: IHF-alpha [H]

Number of amino acids: Translated: 94; Mature: 93

Protein sequence:

>94_residues
MTKADIFEKVSSNLGYTKKESAELVEAVFSLIKSTLESGEKIKIAGFGNFEVKQKADRRGRNPQNGETITIEARRILTFK
PSGVLKTAINGAKQ

Sequences:

>Translated_94_residues
MTKADIFEKVSSNLGYTKKESAELVEAVFSLIKSTLESGEKIKIAGFGNFEVKQKADRRGRNPQNGETITIEARRILTFK
PSGVLKTAINGAKQ
>Mature_93_residues
TKADIFEKVSSNLGYTKKESAELVEAVFSLIKSTLESGEKIKIAGFGNFEVKQKADRRGRNPQNGETITIEARRILTFKP
SGVLKTAINGAKQ

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. It is necessary for normal cell growth and the production o

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1788005, Length=92, Percent_Identity=45.6521739130435, Blast_Score=92, Evalue=5e-21,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=33.3333333333333, Blast_Score=71, Evalue=1e-14,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=32.967032967033, Blast_Score=64, Evalue=2e-12,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=30.3370786516854, Blast_Score=58, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10331; Mature: 10200

Theoretical pI: Translated: 10.54; Mature: 10.54

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKADIFEKVSSNLGYTKKESAELVEAVFSLIKSTLESGEKIKIAGFGNFEVKQKADRRG
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCC
RNPQNGETITIEARRILTFKPSGVLKTAINGAKQ
CCCCCCCEEEEEEEEEEEECCCCHHHHHHCCCCC
>Mature Secondary Structure 
TKADIFEKVSSNLGYTKKESAELVEAVFSLIKSTLESGEKIKIAGFGNFEVKQKADRRG
CHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCC
RNPQNGETITIEARRILTFKPSGVLKTAINGAKQ
CCCCCCCEEEEEEEEEEEECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11133949 [H]