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The map label for this gene is 118580290

Identifier: 118580290

GI number: 118580290

Start: 2012572

End: 2013363

Strand: Reverse

Name: 118580290

Synonym: Ppro_1871

Alternate gene names: NA

Gene position: 2013363-2012572 (Counterclockwise)

Preceding gene: 118580291

Following gene: 118580289

Centisome position: 50.23

GC content: 50.25

Gene sequence:

>792_bases
GTGATACGTCCTTATCTATTGTCAATTACAGCATTATTGCTGAGTGCCGGAATTGCGTTCGCTGCTGACACCTCGTGCCC
TGAACATTTTACCGGTGGAAAAGCACCTGACATCATCAATCAGAAAATGACCGCCAAGACCCTTGAAATCTGTTATTCGG
GTTATGCGCTCAAGCATTCCGGCATTACCCGCACTCCACTTTACTCAGCAGAACACCTGACCCGAGAACGCATGCTTCAT
GGCAAGGGGCTTAAGCGCCAAAGCAAGTTCTTCCCGGATACCAACATCCCCGCTTCTGAAAGAGCGGAACTCCATCATTA
TGCGCGGTCAGGTTATGACCGTGGCCATGTTGCGCCTTCTGCAGATATGTTCGATATACAATCGCAGCAAGAGTGTTTCA
GCCTTGCCAACATGGTTCCGCAAGTTCCAGAGAACAACCGTGGCCCCTGGGAAGGTATTGAATCTACGATTCGGAAAATG
GCCAAAGACCGAGGCGACATCTATGTTGTCACCGGCCCGATTTACCAGGGTGAAATTCAGAAAATAGGCGGCGCCGTCAT
GGTGCCGACCAAACTCTTCAAAGCGGTGTATGACCCGCATCGTCAGGAATCAGGAGCTTATCTGATAGACAATACTGCAG
ATGCGCAACCTGAGAAAATCAGTGTCGCGGACTTGGAGAAGATTACCGGAATCAGCCTGTTCCCAGCAGTCGGTGACGCT
ACAAAATCTCTACTCATGCGCCTACCTGAACCGAAGTCATATAAGGAACGGAAGCGGAAAGGTGATCGGTGA

Upstream 100 bases:

>100_bases
GCAACCCGCAGAACGGTGAGACAATCACCATCGAGGCACGTCGTATCCTTACCTTTAAGCCGAGCGGTGTCCTTAAAACA
GCGATTAACGGTGCAAAGCA

Downstream 100 bases:

>100_bases
TGGCTAAGAAATCATTTTCACCCTATCATAATGAAGCCGATAGTCTCCAGATAGCTGACCTGACTATTGAAAACCGGTTA
GACCGGATTTGTATCTACGG

Product: DNA/RNA non-specific endonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MIRPYLLSITALLLSAGIAFAADTSCPEHFTGGKAPDIINQKMTAKTLEICYSGYALKHSGITRTPLYSAEHLTRERMLH
GKGLKRQSKFFPDTNIPASERAELHHYARSGYDRGHVAPSADMFDIQSQQECFSLANMVPQVPENNRGPWEGIESTIRKM
AKDRGDIYVVTGPIYQGEIQKIGGAVMVPTKLFKAVYDPHRQESGAYLIDNTADAQPEKISVADLEKITGISLFPAVGDA
TKSLLMRLPEPKSYKERKRKGDR

Sequences:

>Translated_263_residues
MIRPYLLSITALLLSAGIAFAADTSCPEHFTGGKAPDIINQKMTAKTLEICYSGYALKHSGITRTPLYSAEHLTRERMLH
GKGLKRQSKFFPDTNIPASERAELHHYARSGYDRGHVAPSADMFDIQSQQECFSLANMVPQVPENNRGPWEGIESTIRKM
AKDRGDIYVVTGPIYQGEIQKIGGAVMVPTKLFKAVYDPHRQESGAYLIDNTADAQPEKISVADLEKITGISLFPAVGDA
TKSLLMRLPEPKSYKERKRKGDR
>Mature_263_residues
MIRPYLLSITALLLSAGIAFAADTSCPEHFTGGKAPDIINQKMTAKTLEICYSGYALKHSGITRTPLYSAEHLTRERMLH
GKGLKRQSKFFPDTNIPASERAELHHYARSGYDRGHVAPSADMFDIQSQQECFSLANMVPQVPENNRGPWEGIESTIRKM
AKDRGDIYVVTGPIYQGEIQKIGGAVMVPTKLFKAVYDPHRQESGAYLIDNTADAQPEKISVADLEKITGISLFPAVGDA
TKSLLMRLPEPKSYKERKRKGDR

Specific function: Unknown

COG id: COG1864

COG function: function code F; DNA/RNA endonuclease G, NUC1

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA/RNA non-specific endonuclease family [H]

Homologues:

Organism=Homo sapiens, GI224451073, Length=208, Percent_Identity=32.6923076923077, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI224451075, Length=178, Percent_Identity=33.7078651685393, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI53759134, Length=154, Percent_Identity=32.4675324675325, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17505967, Length=205, Percent_Identity=31.219512195122, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6322253, Length=213, Percent_Identity=31.4553990610329, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24581065, Length=209, Percent_Identity=28.2296650717703, Blast_Score=91, Evalue=9e-19,
Organism=Drosophila melanogaster, GI20129899, Length=208, Percent_Identity=29.3269230769231, Blast_Score=84, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018524
- InterPro:   IPR001604
- InterPro:   IPR020821 [H]

Pfam domain/function: PF01223 Endonuclease_NS [H]

EC number: 3.1.30.-

Molecular weight: Translated: 29197; Mature: 29197

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPYLLSITALLLSAGIAFAADTSCPEHFTGGKAPDIINQKMTAKTLEICYSGYALKHS
CCCHHHHHHHHHHHHCCHHHEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECC
GITRTPLYSAEHLTRERMLHGKGLKRQSKFFPDTNIPASERAELHHYARSGYDRGHVAPS
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ADMFDIQSQQECFSLANMVPQVPENNRGPWEGIESTIRKMAKDRGDIYVVTGPIYQGEIQ
CCHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
KIGGAVMVPTKLFKAVYDPHRQESGAYLIDNTADAQPEKISVADLEKITGISLFPAVGDA
HHCCEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEECHHHHHHHCCCCCCCCCCHH
TKSLLMRLPEPKSYKERKRKGDR
HHHHHHHCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MIRPYLLSITALLLSAGIAFAADTSCPEHFTGGKAPDIINQKMTAKTLEICYSGYALKHS
CCCHHHHHHHHHHHHCCHHHEECCCCCHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEECC
GITRTPLYSAEHLTRERMLHGKGLKRQSKFFPDTNIPASERAELHHYARSGYDRGHVAPS
CCCCCCCCCHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
ADMFDIQSQQECFSLANMVPQVPENNRGPWEGIESTIRKMAKDRGDIYVVTGPIYQGEIQ
CCHHHCCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHH
KIGGAVMVPTKLFKAVYDPHRQESGAYLIDNTADAQPEKISVADLEKITGISLFPAVGDA
HHCCEEEHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCEECHHHHHHHCCCCCCCCCCHH
TKSLLMRLPEPKSYKERKRKGDR
HHHHHHHCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9403685 [H]