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The map label for this gene is glnS [H]

Identifier: 118580145

GI number: 118580145

Start: 1853425

End: 1855122

Strand: Direct

Name: glnS [H]

Synonym: Ppro_1725

Alternate gene names: 118580145

Gene position: 1853425-1855122 (Clockwise)

Preceding gene: 118580144

Following gene: 118580146

Centisome position: 46.24

GC content: 63.13

Gene sequence:

>1698_bases
ATGTCAACAGAAAGCGTAGCTCCATCCAACTTCCTCCGTACGATCATCGATGACGACCTGAAAAGCGGCAAGCACGGCTC
AATCGTGACCCGTTTCCCGCCCGAGCCCAACGGATATCTGCACATCGGCCATGCCAAGTCCATCTGCCTCAACTTCGGCC
TGGCCCGGGACTTCGGCGGCCGCTGCCACCTGCGCTTCGATGACACCAATCCGGCCAAGGAGGATAGGGAGTACATCGAA
TCCATCAAGGAGAGCGTGCGCTGGCTCGGTTTCGACTGGGGAGAACACCTGTACTATGCTTCCGACTATTTCCAGCAGCT
CTACGACTGGGCCGAGTACCTGATCCAACAGGGCAAGGCCTATGTTGAGGACCTGAGCGCCGAGGAGATCCGCGCTCACC
GCGGCACCCTGACCGAACCGGGAAAGGAGAGTCCCTTCCGCAATCGCTCCGTTGAGGAGAACCTGACCCTGTTCCGCGCC
ATGAAGAGGGGCGATTTCCCCGAGGGGAGCAGGGTCCTGCGAGCCAGGATCGATATGTCCTCCCCCAACCTGAACCTGCG
CGACCCGGTGCTGTACCGCATCATCCACGCCCCCCACCCGCACGTGGGGGACAGCTGGCGCATCTACCCCATGTACGACT
TTGCCCATGGCCAGTCCGACGCCATCGAGGGGATCACCCACTCCATCTGCACCCTGGAGTTCGAGGACCACAAGCCGCTC
TACGAGTGGTTCCTGGACAACCTGCCGGTGCCGGCCCGGCCGCGGCAGTACGAATTCGCCCGCCTCAATCTGACCTACAC
GGTGATGAGCAAGCGCAAGCTGAACGAGCTGGTCACCCAGCGCATCGTGGGTGGATGGGACGACCCCCGCCTGCCGACCC
TGATGGGGCTGCGCCGGCGCGGCTACACCCCCGCCTCCATCCGCGCCTTCTGCGAGCGCATCGGCGTCGGCCGCGGGGAC
TCCTGGATCGACATGTCGGTGCTGGAGGAGTGTCTGCGCGAGGACCTGAACGAACGGGCGCCGCGGGTCATGGGAGTGCT
GAAGCCCCTCAAGGTGGTCATCGACAACTATCCCGAGGGGCAGGTGGAGGAGTTCGAGGCTGCCAACCATCCCCAAAAGC
CGGAGATGGGCAGCCGCACGGTCTCCTTTTCCCGCGAACTGTTCATCGAACAGGACGACTTCATGCAGGAACCGTCTAAG
GGGTTCTTCCGCATGGCCCCGGGCAAGGAGGTGCGCCTGCGTTACGCCTATATCGTGCGCTGCACCGGCGTTGTCAGCGA
CGACAACGGCGTCGTCACCGAGGTGCACTGCCAGTACGACCCGGCCTCGCGGGGGGGGACCGCCGCTGACGGCCGCAAGA
TCAAGGGGACCATCCACTGGGTGTCGGCCCCCCATGCCGTTGCTGCCGAGGTGCGGCTGTTCGACTACCTGTTCAACGAC
GCCAATCCGGACAGGGGAGGGGTGGACTACAAGCAGTTCCTCAATCCCGATTCGGTGGAAATTCTGACCAACTGCAAGCT
GGAGGCGAGCCTGGCCACTGCCGGCAGCGACACCCAGGTGCAGTTCGAGCGCCTGGGCTACTTCCGCACCGACTCCGGGG
ACTCCCGGCCAGGCAGACTGGTCTTCAACCGTAGCGTGACCCTGAAAGATACCCGCGCCAAGAAGCTAGACATAAAGGAA
CAGCATTCAACCATATGA

Upstream 100 bases:

>100_bases
CGGTACCTTCGTCGATCTGCGAATCATCCAGGTGTTCCAGAATTCGCTCCTGGGGGAACTGCTCCCGGGGTGACCAACTT
GAAATCTTCAGAGGGAAACC

Downstream 100 bases:

>100_bases
AAAACAACGTCAACAGATTCGGCTATGTCTCCATCGTCGGTCGTCCCAACGTGGGCAAGTCCACGTTGCTCAACCGCATC
ATCGGCGAGAAGATCGCCAT

Product: glutaminyl-tRNA synthetase

Products: NA

Alternate protein names: Glutamine--tRNA ligase; GlnRS [H]

Number of amino acids: Translated: 565; Mature: 564

Protein sequence:

>565_residues
MSTESVAPSNFLRTIIDDDLKSGKHGSIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGGRCHLRFDDTNPAKEDREYIE
SIKESVRWLGFDWGEHLYYASDYFQQLYDWAEYLIQQGKAYVEDLSAEEIRAHRGTLTEPGKESPFRNRSVEENLTLFRA
MKRGDFPEGSRVLRARIDMSSPNLNLRDPVLYRIIHAPHPHVGDSWRIYPMYDFAHGQSDAIEGITHSICTLEFEDHKPL
YEWFLDNLPVPARPRQYEFARLNLTYTVMSKRKLNELVTQRIVGGWDDPRLPTLMGLRRRGYTPASIRAFCERIGVGRGD
SWIDMSVLEECLREDLNERAPRVMGVLKPLKVVIDNYPEGQVEEFEAANHPQKPEMGSRTVSFSRELFIEQDDFMQEPSK
GFFRMAPGKEVRLRYAYIVRCTGVVSDDNGVVTEVHCQYDPASRGGTAADGRKIKGTIHWVSAPHAVAAEVRLFDYLFND
ANPDRGGVDYKQFLNPDSVEILTNCKLEASLATAGSDTQVQFERLGYFRTDSGDSRPGRLVFNRSVTLKDTRAKKLDIKE
QHSTI

Sequences:

>Translated_565_residues
MSTESVAPSNFLRTIIDDDLKSGKHGSIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGGRCHLRFDDTNPAKEDREYIE
SIKESVRWLGFDWGEHLYYASDYFQQLYDWAEYLIQQGKAYVEDLSAEEIRAHRGTLTEPGKESPFRNRSVEENLTLFRA
MKRGDFPEGSRVLRARIDMSSPNLNLRDPVLYRIIHAPHPHVGDSWRIYPMYDFAHGQSDAIEGITHSICTLEFEDHKPL
YEWFLDNLPVPARPRQYEFARLNLTYTVMSKRKLNELVTQRIVGGWDDPRLPTLMGLRRRGYTPASIRAFCERIGVGRGD
SWIDMSVLEECLREDLNERAPRVMGVLKPLKVVIDNYPEGQVEEFEAANHPQKPEMGSRTVSFSRELFIEQDDFMQEPSK
GFFRMAPGKEVRLRYAYIVRCTGVVSDDNGVVTEVHCQYDPASRGGTAADGRKIKGTIHWVSAPHAVAAEVRLFDYLFND
ANPDRGGVDYKQFLNPDSVEILTNCKLEASLATAGSDTQVQFERLGYFRTDSGDSRPGRLVFNRSVTLKDTRAKKLDIKE
QHSTI
>Mature_564_residues
STESVAPSNFLRTIIDDDLKSGKHGSIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGGRCHLRFDDTNPAKEDREYIES
IKESVRWLGFDWGEHLYYASDYFQQLYDWAEYLIQQGKAYVEDLSAEEIRAHRGTLTEPGKESPFRNRSVEENLTLFRAM
KRGDFPEGSRVLRARIDMSSPNLNLRDPVLYRIIHAPHPHVGDSWRIYPMYDFAHGQSDAIEGITHSICTLEFEDHKPLY
EWFLDNLPVPARPRQYEFARLNLTYTVMSKRKLNELVTQRIVGGWDDPRLPTLMGLRRRGYTPASIRAFCERIGVGRGDS
WIDMSVLEECLREDLNERAPRVMGVLKPLKVVIDNYPEGQVEEFEAANHPQKPEMGSRTVSFSRELFIEQDDFMQEPSKG
FFRMAPGKEVRLRYAYIVRCTGVVSDDNGVVTEVHCQYDPASRGGTAADGRKIKGTIHWVSAPHAVAAEVRLFDYLFNDA
NPDRGGVDYKQFLNPDSVEILTNCKLEASLATAGSDTQVQFERLGYFRTDSGDSRPGRLVFNRSVTLKDTRAKKLDIKEQ
HSTI

Specific function: Unknown

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4826960, Length=537, Percent_Identity=44.5065176908752, Blast_Score=421, Evalue=1e-117,
Organism=Homo sapiens, GI62241042, Length=516, Percent_Identity=34.4961240310078, Blast_Score=281, Evalue=8e-76,
Organism=Escherichia coli, GI1786895, Length=554, Percent_Identity=57.942238267148, Blast_Score=661, Evalue=0.0,
Organism=Escherichia coli, GI1788743, Length=310, Percent_Identity=27.0967741935484, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17543332, Length=532, Percent_Identity=42.8571428571429, Blast_Score=404, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17511007, Length=522, Percent_Identity=33.3333333333333, Blast_Score=242, Evalue=4e-64,
Organism=Saccharomyces cerevisiae, GI6324742, Length=567, Percent_Identity=39.6825396825397, Blast_Score=395, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321192, Length=526, Percent_Identity=35.171102661597, Blast_Score=298, Evalue=2e-81,
Organism=Drosophila melanogaster, GI17864488, Length=534, Percent_Identity=41.7602996254682, Blast_Score=406, Evalue=1e-113,
Organism=Drosophila melanogaster, GI24649466, Length=375, Percent_Identity=37.8666666666667, Blast_Score=259, Evalue=3e-69,

Paralogues:

None

Copy number: 520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 1200 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR004514
- InterPro:   IPR022861
- InterPro:   IPR000924
- InterPro:   IPR020061
- InterPro:   IPR020058
- InterPro:   IPR020059
- InterPro:   IPR020056
- InterPro:   IPR011035
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00749 tRNA-synt_1c; PF03950 tRNA-synt_1c_C [H]

EC number: =6.1.1.18 [H]

Molecular weight: Translated: 64572; Mature: 64441

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTESVAPSNFLRTIIDDDLKSGKHGSIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGG
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCHHHHHHHCCHHHCCCC
RCHLRFDDTNPAKEDREYIESIKESVRWLGFDWGEHLYYASDYFQQLYDWAEYLIQQGKA
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
YVEDLSAEEIRAHRGTLTEPGKESPFRNRSVEENLTLFRAMKRGDFPEGSRVLRARIDMS
HHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
SPNLNLRDPVLYRIIHAPHPHVGDSWRIYPMYDFAHGQSDAIEGITHSICTLEFEDHKPL
CCCCCCCCHHHHHEECCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCEEEEEECCCCCH
YEWFLDNLPVPARPRQYEFARLNLTYTVMSKRKLNELVTQRIVGGWDDPRLPTLMGLRRR
HHHHHHCCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GYTPASIRAFCERIGVGRGDSWIDMSVLEECLREDLNERAPRVMGVLKPLKVVIDNYPEG
CCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QVEEFEAANHPQKPEMGSRTVSFSRELFIEQDDFMQEPSKGFFRMAPGKEVRLRYAYIVR
CHHHHHHCCCCCCCCCCCCCCCCHHHHEECCHHHHCCCCCCCEEECCCCCEEEEEEEEEE
CTGVVSDDNGVVTEVHCQYDPASRGGTAADGRKIKGTIHWVSAPHAVAAEVRLFDYLFND
EEEEEECCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCC
ANPDRGGVDYKQFLNPDSVEILTNCKLEASLATAGSDTQVQFERLGYFRTDSGDSRPGRL
CCCCCCCCCHHHHCCCCCEEEEECCEEEEEEECCCCCCEEEHHHCCEEECCCCCCCCCEE
VFNRSVTLKDTRAKKLDIKEQHSTI
EEECCEEEECCCCHHCCCHHHCCCC
>Mature Secondary Structure 
STESVAPSNFLRTIIDDDLKSGKHGSIVTRFPPEPNGYLHIGHAKSICLNFGLARDFGG
CCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCEEEECCHHHHHHHCCHHHCCCC
RCHLRFDDTNPAKEDREYIESIKESVRWLGFDWGEHLYYASDYFQQLYDWAEYLIQQGKA
EEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCHH
YVEDLSAEEIRAHRGTLTEPGKESPFRNRSVEENLTLFRAMKRGDFPEGSRVLRARIDMS
HHHHCCHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCC
SPNLNLRDPVLYRIIHAPHPHVGDSWRIYPMYDFAHGQSDAIEGITHSICTLEFEDHKPL
CCCCCCCCHHHHHEECCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHCEEEEEECCCCCH
YEWFLDNLPVPARPRQYEFARLNLTYTVMSKRKLNELVTQRIVGGWDDPRLPTLMGLRRR
HHHHHHCCCCCCCCCCCEEEEEEEEEEEHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHC
GYTPASIRAFCERIGVGRGDSWIDMSVLEECLREDLNERAPRVMGVLKPLKVVIDNYPEG
CCCCHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
QVEEFEAANHPQKPEMGSRTVSFSRELFIEQDDFMQEPSKGFFRMAPGKEVRLRYAYIVR
CHHHHHHCCCCCCCCCCCCCCCCHHHHEECCHHHHCCCCCCCEEECCCCCEEEEEEEEEE
CTGVVSDDNGVVTEVHCQYDPASRGGTAADGRKIKGTIHWVSAPHAVAAEVRLFDYLFND
EEEEEECCCCEEEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHHCC
ANPDRGGVDYKQFLNPDSVEILTNCKLEASLATAGSDTQVQFERLGYFRTDSGDSRPGRL
CCCCCCCCCHHHHCCCCCEEEEECCEEEEEEECCCCCCEEEHHHCCEEECCCCCCCCCEE
VFNRSVTLKDTRAKKLDIKEQHSTI
EEECCEEEECCCCHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]