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The map label for this gene is yabD [H]

Identifier: 118580123

GI number: 118580123

Start: 1828972

End: 1830357

Strand: Direct

Name: yabD [H]

Synonym: Ppro_1702

Alternate gene names: 118580123

Gene position: 1828972-1830357 (Clockwise)

Preceding gene: 118580122

Following gene: 118580127

Centisome position: 45.63

GC content: 64.07

Gene sequence:

>1386_bases
ATGTCGCACACACCTGTTCTGATCGACTCCCATGCCCACATTTACTACCGCGACTATGACGACGACTTCGAGGCCATGCT
GCAGCGCGCGGCCGATACCGGCGTGGCCGCCATACTGGTGGTCGGCACCGACCTGGAAACCAGCCGCCAGTCGGTGGAAC
TGGCGGAGAGGTATCCCCGGATCTACGCAGCCGTCGGCATCCACCCCCACGATGCAAGCCAGGTGACCGAGGAGAGCTAC
CAGGCCATCCGCGAGCTGGCCCTCTCCAGCCCGAAAGTCGTTGCCATCGGCGAGATTGGACTGGATTTCTACCGCGACCG
TTCCCCCCGCGACGTGCAGGAGGCCGTGTTCCTGCGTCTGCTGCGCCTGGCCGGGGAGCTGGACATGCCGGTGATCATCC
ACGATCGCGATGCCCACCAGCGGGTGCTGGAATGCCTGCGCCAGGAGGGAACATCGCGCGGCGTGCTGCACTGTTTCTCC
GGCGACGCGGCCATGGCGGCCGAGGCCATCGCCATGGGACTGTACATCTCCATCCCCGGCACCATTACCTATCCCTCCAA
CGACGCCCTGCGCCAGGTGGTGCGGGTCACCAGCATCGACCGCATGCTGGTGGAGACCGACTGCCCCTACCTGACCCCGG
TGCCGCACCGCGGCAGGCGCAACGAGCCGGCTCATGTGCTGCTGGCTGCCCAGCGGGTGGCCGAGGTGAAGGGGCTTACC
CTGGATGACGTGGGCCGCATCACCACCAAGAACGCGAGCGACCTGTTCGGCATGCGTCTCTGGGACCAGGCCGCCAAAAT
CGCTTACCGCATCCGCACCTCCCTCTACCTGAATATCACCAACCGCTGCTCCAACCGCTGCTCCTTCTGCGCCAAGTTCG
ATGATTTCACCGTTAAGGGGCACAACCTGCTGCTGGACGCAGAACCGTCCTTTTTGGAGGTCATGGCGGCAATCGGTCAG
CCGGATGCCGACCTGGATGAGGTGGTCTTCTGCGGCTTTGGCGAGTCGTTGCTCCGGCTGGATCTTGTCAAACAGGTGGC
GGCCGAAATGAAGGGGCGCGGTTTTCGTATCCGCATCAATACCGACGGTCAGGCCAACCTGGTGCACGGCCGCAACATCC
TGCCCGAACTGGTCGGGCTGGTGGACAGTATCTCCGTCAGCCTCAACGCACCAGACAGCCAGACCTATGTCAGGCTTTGC
TCCACCCCCTTTGGGGAGGCGGGTTTTGCGGGTGTGTGCGACTTCATCCGTGAGGCGCGGCAGTACATCCCCCAGGTGGT
GGCCAGCGCCGTCACCGTGCCGGGGGTGGATATCCCGGCCTGTAGCATGCTTGCCGAATCCCTGGGAGTTCAGTTTCGGG
TCAGGGAGTACGAGGAGGTCGGCTAG

Upstream 100 bases:

>100_bases
TCCGGCATTACGCTCGATCCGTCCTCCATGTGTCGCGGTTCCTCCCCTTCAGAGTAAATTCCAACGTAAGATCGCATACA
AAAGCCAAAGGAAACAGTTA

Downstream 100 bases:

>100_bases
GGAGGGAGATGGTAGGGAAAAGCAACGAAAAAGCCACATCGGATGATGTGGCTTTTTCGTTGCCTGATCACGGGCTTTAG
CGGCAGACGATGTCGTACAG

Product: TatD family hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MSHTPVLIDSHAHIYYRDYDDDFEAMLQRAADTGVAAILVVGTDLETSRQSVELAERYPRIYAAVGIHPHDASQVTEESY
QAIRELALSSPKVVAIGEIGLDFYRDRSPRDVQEAVFLRLLRLAGELDMPVIIHDRDAHQRVLECLRQEGTSRGVLHCFS
GDAAMAAEAIAMGLYISIPGTITYPSNDALRQVVRVTSIDRMLVETDCPYLTPVPHRGRRNEPAHVLLAAQRVAEVKGLT
LDDVGRITTKNASDLFGMRLWDQAAKIAYRIRTSLYLNITNRCSNRCSFCAKFDDFTVKGHNLLLDAEPSFLEVMAAIGQ
PDADLDEVVFCGFGESLLRLDLVKQVAAEMKGRGFRIRINTDGQANLVHGRNILPELVGLVDSISVSLNAPDSQTYVRLC
STPFGEAGFAGVCDFIREARQYIPQVVASAVTVPGVDIPACSMLAESLGVQFRVREYEEVG

Sequences:

>Translated_461_residues
MSHTPVLIDSHAHIYYRDYDDDFEAMLQRAADTGVAAILVVGTDLETSRQSVELAERYPRIYAAVGIHPHDASQVTEESY
QAIRELALSSPKVVAIGEIGLDFYRDRSPRDVQEAVFLRLLRLAGELDMPVIIHDRDAHQRVLECLRQEGTSRGVLHCFS
GDAAMAAEAIAMGLYISIPGTITYPSNDALRQVVRVTSIDRMLVETDCPYLTPVPHRGRRNEPAHVLLAAQRVAEVKGLT
LDDVGRITTKNASDLFGMRLWDQAAKIAYRIRTSLYLNITNRCSNRCSFCAKFDDFTVKGHNLLLDAEPSFLEVMAAIGQ
PDADLDEVVFCGFGESLLRLDLVKQVAAEMKGRGFRIRINTDGQANLVHGRNILPELVGLVDSISVSLNAPDSQTYVRLC
STPFGEAGFAGVCDFIREARQYIPQVVASAVTVPGVDIPACSMLAESLGVQFRVREYEEVG
>Mature_460_residues
SHTPVLIDSHAHIYYRDYDDDFEAMLQRAADTGVAAILVVGTDLETSRQSVELAERYPRIYAAVGIHPHDASQVTEESYQ
AIRELALSSPKVVAIGEIGLDFYRDRSPRDVQEAVFLRLLRLAGELDMPVIIHDRDAHQRVLECLRQEGTSRGVLHCFSG
DAAMAAEAIAMGLYISIPGTITYPSNDALRQVVRVTSIDRMLVETDCPYLTPVPHRGRRNEPAHVLLAAQRVAEVKGLTL
DDVGRITTKNASDLFGMRLWDQAAKIAYRIRTSLYLNITNRCSNRCSFCAKFDDFTVKGHNLLLDAEPSFLEVMAAIGQP
DADLDEVVFCGFGESLLRLDLVKQVAAEMKGRGFRIRINTDGQANLVHGRNILPELVGLVDSISVSLNAPDSQTYVRLCS
TPFGEAGFAGVCDFIREARQYIPQVVASAVTVPGVDIPACSMLAESLGVQFRVREYEEVG

Specific function: Shows DNAse activity [C]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasmic [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI110349734, Length=266, Percent_Identity=30.8270676691729, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI110349730, Length=266, Percent_Identity=29.6992481203008, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI226061853, Length=271, Percent_Identity=29.1512915129151, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI226061614, Length=259, Percent_Identity=28.957528957529, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI14042943, Length=251, Percent_Identity=25.8964143426295, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=27.6315789473684, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI225903424, Length=206, Percent_Identity=30.5825242718447, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI225903439, Length=229, Percent_Identity=25.764192139738, Blast_Score=87, Evalue=4e-17,
Organism=Escherichia coli, GI48994985, Length=252, Percent_Identity=38.8888888888889, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1787342, Length=255, Percent_Identity=36.8627450980392, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=33.0708661417323, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17559024, Length=282, Percent_Identity=31.5602836879433, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI71980746, Length=261, Percent_Identity=25.2873563218391, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17565396, Length=214, Percent_Identity=28.5046728971963, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24648690, Length=284, Percent_Identity=31.6901408450704, Blast_Score=130, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24586117, Length=276, Percent_Identity=27.1739130434783, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221330018, Length=276, Percent_Identity=27.1739130434783, Blast_Score=95, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278
- InterPro:   IPR015991 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 50885; Mature: 50753

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHTPVLIDSHAHIYYRDYDDDFEAMLQRAADTGVAAILVVGTDLETSRQSVELAERYPR
CCCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCE
IYAAVGIHPHDASQVTEESYQAIRELALSSPKVVAIGEIGLDFYRDRSPRDVQEAVFLRL
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHH
LRLAGELDMPVIIHDRDAHQRVLECLRQEGTSRGVLHCFSGDAAMAAEAIAMGLYISIPG
HHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHEEEEEECCC
TITYPSNDALRQVVRVTSIDRMLVETDCPYLTPVPHRGRRNEPAHVLLAAQRVAEVKGLT
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
LDDVGRITTKNASDLFGMRLWDQAAKIAYRIRTSLYLNITNRCSNRCSFCAKFDDFTVKG
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEHEEEEEEHHHCCCHHHEEEECCCEEEEC
HNLLLDAEPSFLEVMAAIGQPDADLDEVVFCGFGESLLRLDLVKQVAAEMKGRGFRIRIN
CEEEEECCCHHHHHHHHHCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEC
TDGQANLVHGRNILPELVGLVDSISVSLNAPDSQTYVRLCSTPFGEAGFAGVCDFIREAR
CCCCEEEECCCHHHHHHHHHHHHCEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
QYIPQVVASAVTVPGVDIPACSMLAESLGVQFRVREYEEVG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCHHCCC
>Mature Secondary Structure 
SHTPVLIDSHAHIYYRDYDDDFEAMLQRAADTGVAAILVVGTDLETSRQSVELAERYPR
CCCCEEEECCCEEEEECCCCHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHHHHHCCE
IYAAVGIHPHDASQVTEESYQAIRELALSSPKVVAIGEIGLDFYRDRSPRDVQEAVFLRL
EEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHCCCCCCHHHHHHHHHH
LRLAGELDMPVIIHDRDAHQRVLECLRQEGTSRGVLHCFSGDAAMAAEAIAMGLYISIPG
HHHHCCCCCCEEEECCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHEEEEEECCC
TITYPSNDALRQVVRVTSIDRMLVETDCPYLTPVPHRGRRNEPAHVLLAAQRVAEVKGLT
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
LDDVGRITTKNASDLFGMRLWDQAAKIAYRIRTSLYLNITNRCSNRCSFCAKFDDFTVKG
HHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEHEEEEEEHHHCCCHHHEEEECCCEEEEC
HNLLLDAEPSFLEVMAAIGQPDADLDEVVFCGFGESLLRLDLVKQVAAEMKGRGFRIRIN
CEEEEECCCHHHHHHHHHCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEC
TDGQANLVHGRNILPELVGLVDSISVSLNAPDSQTYVRLCSTPFGEAGFAGVCDFIREAR
CCCCEEEECCCHHHHHHHHHHHHCEEEECCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHH
QYIPQVVASAVTVPGVDIPACSMLAESLGVQFRVREYEEVG
HHHHHHHHHHHCCCCCCCCHHHHHHHHHCCEEEECCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]