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The map label for this gene is yacO [H]

Identifier: 118580099

GI number: 118580099

Start: 1795883

End: 1796638

Strand: Direct

Name: yacO [H]

Synonym: Ppro_1677

Alternate gene names: 118580099

Gene position: 1795883-1796638 (Clockwise)

Preceding gene: 118580098

Following gene: 118580101

Centisome position: 44.81

GC content: 63.23

Gene sequence:

>756_bases
ATGAGAGAGGAACTGGTATTTGGCGTCAATCCGGTTCGGGAGGCGCTGCGCGGCAAACGTGAAATCTTCGGGTTGTACGT
TCAGTCAACGGCCACGGACCACCGTCTGGACAAGATCCTGGAACTGGCCAGGGAGCGGGGCGTCAGGGTCATCAGGCGCG
AGCGTGAGGACCTGACCCGCATGTGCGGCTCGTCCCACCACCAGGGAATGGCCCTCAAGGTGGCCCCCTTCAGCTATGCC
GACCTGGATGACCTGATCGAAGCAGGCGACCGTGAGGATGCTGCCGGTTTTCTGCTGGTCCTGGACGGTATACAGGATCC
CCATAACCTGGGGGCGCTGATCCGTACGGCAGCCTGTGCCGGCGCCAGCGGCGTCGTCATTCCCCGCGACCGGGCCTGCG
CCATTACGCCGGCAGCGGAGAAGGCCTCGGCCGGTGCAGTGGAAACCATAACGGTGGCCCAGGTAACCAACATTGCTCAG
TCACTGGAGAAGTTGAAGAGGTCTGGCTACTGGGTCTATGGTCTGAGCGGCGAGGCGGATGCCTCGCTCTATGAAGTCGC
TTTTTCCGGCAAGATCGCTCTGGTGATCGGTGGCGAAGGGGAGGGGATCAGGCCGCTGGTGCGAAAACAGTGCGATGCGC
TGGTCTCCATCCCCCTGTACGGCGGTGTCGGCTCCCTGAATGCCTCGGTAGCCGGTGGTATCGCCCTGTACGAGGTGGCC
CGCTGTCTGCGGGGCGAGAAACCGGGACGGAGCTGA

Upstream 100 bases:

>100_bases
AGGGGGCCGATTATCTGGTAATCGGGCGCCCCATCGCAAAGGCGGACGATCCGGTCCGTGCCGTTGATATGATCGTGGAC
GAGATCGTTGCGGGGTGCCC

Downstream 100 bases:

>100_bases
CGGAGAAAGCTGCCCGGTTCCTTGTCCCGTGCGCTTGCCGGCGCCGGCAGTTTTTCTCCTGATCATGATTTTCGATTTTT
GAACGCGGCATACCTGGCCA

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MREELVFGVNPVREALRGKREIFGLYVQSTATDHRLDKILELARERGVRVIRREREDLTRMCGSSHHQGMALKVAPFSYA
DLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACAGASGVVIPRDRACAITPAAEKASAGAVETITVAQVTNIAQ
SLEKLKRSGYWVYGLSGEADASLYEVAFSGKIALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVA
RCLRGEKPGRS

Sequences:

>Translated_251_residues
MREELVFGVNPVREALRGKREIFGLYVQSTATDHRLDKILELARERGVRVIRREREDLTRMCGSSHHQGMALKVAPFSYA
DLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACAGASGVVIPRDRACAITPAAEKASAGAVETITVAQVTNIAQ
SLEKLKRSGYWVYGLSGEADASLYEVAFSGKIALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVA
RCLRGEKPGRS
>Mature_251_residues
MREELVFGVNPVREALRGKREIFGLYVQSTATDHRLDKILELARERGVRVIRREREDLTRMCGSSHHQGMALKVAPFSYA
DLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACAGASGVVIPRDRACAITPAAEKASAGAVETITVAQVTNIAQ
SLEKLKRSGYWVYGLSGEADASLYEVAFSGKIALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVA
RCLRGEKPGRS

Specific function: Unknown

COG id: COG0566

COG function: function code J; rRNA methylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA methyltransferase TrmH family [H]

Homologues:

Organism=Homo sapiens, GI40068479, Length=262, Percent_Identity=32.0610687022901, Blast_Score=124, Evalue=6e-29,
Organism=Escherichia coli, GI1790623, Length=242, Percent_Identity=38.8429752066116, Blast_Score=182, Evalue=1e-47,
Organism=Escherichia coli, GI1788935, Length=241, Percent_Identity=27.3858921161826, Blast_Score=87, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17555908, Length=259, Percent_Identity=27.4131274131274, Blast_Score=87, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6324775, Length=293, Percent_Identity=24.5733788395904, Blast_Score=87, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004441
- InterPro:   IPR001537
- InterPro:   IPR013123 [H]

Pfam domain/function: PF00588 SpoU_methylase; PF08032 SpoU_sub_bind [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 26790; Mature: 26790

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREELVFGVNPVREALRGKREIFGLYVQSTATDHRLDKILELARERGVRVIRREREDLTR
CCCCEEECCHHHHHHHCCHHHHHEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
MCGSSHHQGMALKVAPFSYADLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACA
HHCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHC
GASGVVIPRDRACAITPAAEKASAGAVETITVAQVTNIAQSLEKLKRSGYWVYGLSGEAD
CCCCEEEECCCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
ASLYEVAFSGKIALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVA
CHHEEEEECCEEEEEECCCCCCCHHHHHHHHHHEEEEECCCCCCCCCHHHHCHHHHHHHH
RCLRGEKPGRS
HHHCCCCCCCC
>Mature Secondary Structure
MREELVFGVNPVREALRGKREIFGLYVQSTATDHRLDKILELARERGVRVIRREREDLTR
CCCCEEECCHHHHHHHCCHHHHHEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHH
MCGSSHHQGMALKVAPFSYADLDDLIEAGDREDAAGFLLVLDGIQDPHNLGALIRTAACA
HHCCCCCCCEEEEECCCCCCCHHHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHC
GASGVVIPRDRACAITPAAEKASAGAVETITVAQVTNIAQSLEKLKRSGYWVYGLSGEAD
CCCCEEEECCCCEEECCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC
ASLYEVAFSGKIALVIGGEGEGIRPLVRKQCDALVSIPLYGGVGSLNASVAGGIALYEVA
CHHEEEEECCEEEEEECCCCCCCHHHHHHHHHHEEEEECCCCCCCCCHHHHCHHHHHHHH
RCLRGEKPGRS
HHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 7510287; 3145906 [H]