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The map label for this gene is ribE [H]

Identifier: 118580018

GI number: 118580018

Start: 1705430

End: 1706071

Strand: Reverse

Name: ribE [H]

Synonym: Ppro_1595

Alternate gene names: 118580018

Gene position: 1706071-1705430 (Counterclockwise)

Preceding gene: 118580019

Following gene: 118580017

Centisome position: 42.57

GC content: 63.24

Gene sequence:

>642_bases
ATGTTCACCGGCCTGATCGAAGATACCGGGCGGGTGACCGCCTTTGAACGGCGCGGCAAGGCCGGCCTGCTGCGGGTCGC
GAGCTCCCTTCCCCTGGACGAGATTGCCATCGGCGACTCGGTTGCGGTCAACGGGGCCTGCCTGACCGTCACCGAGAAAC
GCGAGGGAACGCTGACGTTCGACGTATCCCCCGAGTCGCTCACAGCCACGACCCTGGGCAGCCTGGCAAGTGGAAGCCTG
GTCAACCTGGAACGCGCCCTGCGTTTGGGGGACCGCATGGGGGGGCACATCGTCACCGGACACGTGGACTGTGTCGGCCG
TCTGGCGCGCACGGAGAACAGCTCGCACCACCACGTCCTGGAATTCTCCCTTCCGGCTGGGAACGCACGCTATCTGGTGA
CCAAGGGATCGGTGACCATCGACGGCATCAGCCTGACGGTCAACAGGGTCAGCCAGGACGGCTTCACGGTCAACATCATT
CCCCATACCCTGGAGCGAACCAGCCTGCACAGCTTGCGACCGGGCAATGAGGTCAACATCGAAACCGACATCATCGGAAA
ATACGTTGAACGGCTGACCCAGCCCTGGAAATCCGGCAGTGGCCTGACCATGAGGGCACTGGCCGAGAACGGTTTTCTGT
AG

Upstream 100 bases:

>100_bases
TGGTGGGAAGGACAAGCATGGAGCAGGCATCCAGGCTGAACATTATCAAAGTGAGCCGCAGCGGCATCGATATCGTCGTG
CATGCGCGGTCGGAGGCGCC

Downstream 100 bases:

>100_bases
TCGGCCATCGCCACCCAACTCCCTCCACATGCAGTACATATCCCCTTGACTTACGGGTAAGTCCACTGTATTGTTTTTTA
CCAATAAAATAACACATTAT

Product: riboflavin synthase subunit alpha

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MFTGLIEDTGRVTAFERRGKAGLLRVASSLPLDEIAIGDSVAVNGACLTVTEKREGTLTFDVSPESLTATTLGSLASGSL
VNLERALRLGDRMGGHIVTGHVDCVGRLARTENSSHHHVLEFSLPAGNARYLVTKGSVTIDGISLTVNRVSQDGFTVNII
PHTLERTSLHSLRPGNEVNIETDIIGKYVERLTQPWKSGSGLTMRALAENGFL

Sequences:

>Translated_213_residues
MFTGLIEDTGRVTAFERRGKAGLLRVASSLPLDEIAIGDSVAVNGACLTVTEKREGTLTFDVSPESLTATTLGSLASGSL
VNLERALRLGDRMGGHIVTGHVDCVGRLARTENSSHHHVLEFSLPAGNARYLVTKGSVTIDGISLTVNRVSQDGFTVNII
PHTLERTSLHSLRPGNEVNIETDIIGKYVERLTQPWKSGSGLTMRALAENGFL
>Mature_213_residues
MFTGLIEDTGRVTAFERRGKAGLLRVASSLPLDEIAIGDSVAVNGACLTVTEKREGTLTFDVSPESLTATTLGSLASGSL
VNLERALRLGDRMGGHIVTGHVDCVGRLARTENSSHHHVLEFSLPAGNARYLVTKGSVTIDGISLTVNRVSQDGFTVNII
PHTLERTSLHSLRPGNEVNIETDIIGKYVERLTQPWKSGSGLTMRALAENGFL

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The alpha subunit catalyze

COG id: COG0307

COG function: function code H; Riboflavin synthase alpha chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 lumazine-binding repeats [H]

Homologues:

Organism=Escherichia coli, GI1787952, Length=187, Percent_Identity=39.0374331550802, Blast_Score=126, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319733, Length=203, Percent_Identity=36.4532019704434, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001783
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00677 Lum_binding [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 22792; Mature: 22792

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: PS00693 LUM_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTGLIEDTGRVTAFERRGKAGLLRVASSLPLDEIAIGDSVAVNGACLTVTEKREGTLTF
CCCCCCCCCCCEEEEHHCCCCCEEEHHHCCCCCCEECCCCEEECCEEEEEEECCCCEEEE
DVSPESLTATTLGSLASGSLVNLERALRLGDRMGGHIVTGHVDCVGRLARTENSSHHHVL
EECCCCEEHHHHHHHCCCCEEHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCEEEE
EFSLPAGNARYLVTKGSVTIDGISLTVNRVSQDGFTVNIIPHTLERTSLHSLRPGNEVNI
EEECCCCCEEEEEEECCEEEEEEEEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCEEEE
ETDIIGKYVERLTQPWKSGSGLTMRALAENGFL
EHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC
>Mature Secondary Structure
MFTGLIEDTGRVTAFERRGKAGLLRVASSLPLDEIAIGDSVAVNGACLTVTEKREGTLTF
CCCCCCCCCCCEEEEHHCCCCCEEEHHHCCCCCCEECCCCEEECCEEEEEEECCCCEEEE
DVSPESLTATTLGSLASGSLVNLERALRLGDRMGGHIVTGHVDCVGRLARTENSSHHHVL
EECCCCEEHHHHHHHCCCCEEHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCCEEEE
EFSLPAGNARYLVTKGSVTIDGISLTVNRVSQDGFTVNIIPHTLERTSLHSLRPGNEVNI
EEECCCCCEEEEEEECCEEEEEEEEEEEEECCCCEEEEEECCCCCCCCHHHCCCCCEEEE
ETDIIGKYVERLTQPWKSGSGLTMRALAENGFL
EHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]