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The map label for this gene is glnH [H]

Identifier: 118580017

GI number: 118580017

Start: 1702808

End: 1705150

Strand: Reverse

Name: glnH [H]

Synonym: Ppro_1594

Alternate gene names: 118580017

Gene position: 1705150-1702808 (Counterclockwise)

Preceding gene: 118580018

Following gene: 118580005

Centisome position: 42.54

GC content: 57.79

Gene sequence:

>2343_bases
ATGCGCTACCTTCATATCCCCTTCACGAAACCAGACGCGAAGCAGTTTATTTCTCTTTTTGGCGCCAGCCTGATCTTTTT
CATCTTTGTGACCAGCAGCTCCGTCTGGGGCATGGACAGGACGAAACTGATCATCGGCGGTGACAGCAACAACCTCCCCT
ACGAAGTCCTCCAAAAGGGGGTGCCGGGGGGGTTCAACATCGAACTGATGCGTGCAGTTGCCGAGGTCATGGGCCTTGAC
GTGGAGTTCCGGCTTGGCTCCTGGAACAATGCACGGCGAAACCTGGAGACAGGAAAGATTGACGTGCTTGCCGGTATGTA
CTACTCGGAGGAACGCAGCCGGCAGATGGACTTCTCCGTTCCCCACACCATGGTTACACCCGGTCTGTTCGTTCGTAAGG
GGTCATCCATCCGCTCGTTCCAGGATCTCAAGAGCAAACAGGTTATCGTCCAGGAGGGCGATATTGTCCACGACCTGATG
ACACACTCCGGCATTACTCCCCACATCATCGTCGTGCAGGACGCCGCCCACGCCCTTAAGCTGCTGGCCTCGGGAAAGCA
CGACTGCGTGCTGACACCGTCCAAGCTGCAGGGGGAATACTTCATCAAAACATTCAACCTGACCACGCTGCACGCGGTCA
AGACCGATCTGTCCCAACTGCGCTACTGTTTCGCGGTGCGAACGGGGAACCGGGAACTGCTCTTCAAACTGGACGAGGGG
TTGAACATTCTCAAGGTTAACGGAACCTACCGACGGATCTACGAGAAATGGTTCGGTATCTACGAGAAAGAGGAGCAGTG
GGGGACCATCAGATACTTCGTCGCCGCCCTGACACTGGTCGGCGGACTGCTGCTGGCCATTTTCCTCTGGTCCCGTTCCC
TCCAGCGCCAAGTCAGGAGACGAACCGCAGAACTGGTGGCCAACGAGAACGAACTGCGCCAGGCGCAGGCGGAACTGGAG
CAGCGGGTTGCCGAGCGGACAGCCGATCTGGCGGCCCTGAACGAGAACCTGCACAGGGAAATAGCGGAGCGCGCTCTGAT
TGAAGAGGGGCTCTGCAGGAGCAACCAGCGCCTGGATCTGCTGGCGGAAATGGCCGGCCAGCTACTGAGGAGCGAATCGC
CGCGGAAGGCGGTGCTCTTCCTCTGCCGAAGAGTATTGAACTACCTTGAGTGCGACGTTTTTTTCAACTACCTGATTGAC
GACCAGCGACAGCGTCTGCACCTGAACGCCTGCAGCGGCATTGGAGAAGAAGACGTTGCCAGAATGGAGTGGCTCGACTT
CGGCGTCGGCCTGTGCGGCTGCGCCGCCCGTGACGGTGTGCGCCTGGTGGTCAACAACCTCCAGGATACTGATGACCAGT
ACACAGCACTGGTGAAACCGTTCGGTATCAGGGCCTACGCCTGCCATCCGCTGATCTCCCATGGCCGGACCCTGGGGACG
CTCTCCTTCTGCTCTCGCACCAGATGCGGTTTCAGCGACGATGATCTCGCGCTGATGAAGACTGTGGCCGATCATGTGGC
CATCGCCATGGAGCGCAAGAAAGCAGGAGAACAACTGAAGCAACGCCAGGAACAGCTGGAGGAATTGAACAGGACCCTTG
ACAGGCGGGTACGGGAAGAGGTGATTCTGAACCGGCAGAAGGATCTCATGCTGATCCGCCAAAACCGCCAGGCCGCCCTG
GGCGAGATGCTGGATCACATCGCCCACCAGTGGAAACAGCCGCTGAACGCCCTCTCCCTGATCATCCAGGATCTGGGGGA
ATCATGGTCAAGCGACGAACCGGATGAAGGGAACATCGAAGAGGCGGTGGACAAGACCATGGCGCTGGTGGAGCACATGT
CCCAGACCATCAATGTATTCAGGGACTTTTACCGGCCGGAAAAGGAGAAGAAAGTCTTTCACATCAAGGAATCCATCGAC
AGGGCCCTCTCCTTCATCGAACCGACCCTGAGGGTCCATTCCATCAGCGTTGAACTGGACGTGGAGCCGGGATTGTCGGC
ATTTGGCTACCCCAAGGAATACGCCCAAGTGCTGCTCAACATCCTGGCCAATGCCAGGGATGCCTTCAGGACGAAAAATA
TCCAACAGCCCAGGATGCTCATACGCGCCTGCGGGGAAGACGACAAGGCCTCCGTCACCATCACCGACAATGCCGGCGGC
ATCCCCGAATCGATCATCGACAGGGTCTTCGACCTGTACTTCACCACCAATGAGGCCAACGGCGGCAGCGGCATCGGTCT
GTACATGTCCAAGAACATCATCGAAAAGAGCATGGGGGGCAGCCTGGAGGTCATGAACACCGGCAACGGCACCCAGTTCC
GCATCGACGTAAGCATATCATAA

Upstream 100 bases:

>100_bases
ACTGATGGAGCGGTTTTTTTTTGCGCATCCCCGCCCATGAGACATCATTTCTGGCCCTGAACCCGCGTTTAACAGAATCC
ACAACGGAACAGACACCTTG

Downstream 100 bases:

>100_bases
GGCTCCCATCACTCATCACTCATCACCAGCACACCTTCAACTCCCGGGCAGCCTTGGTCTCGTCCAACCGAGAAACCGGC
ATGGTCAGCGGCGCATCCAG

Product: multi-sensor signal transduction histidine kinase

Products: ADP; phosphate; L-glutamine [Cytoplasm] [C]

Alternate protein names: GlnBP [H]

Number of amino acids: Translated: 780; Mature: 780

Protein sequence:

>780_residues
MRYLHIPFTKPDAKQFISLFGASLIFFIFVTSSSVWGMDRTKLIIGGDSNNLPYEVLQKGVPGGFNIELMRAVAEVMGLD
VEFRLGSWNNARRNLETGKIDVLAGMYYSEERSRQMDFSVPHTMVTPGLFVRKGSSIRSFQDLKSKQVIVQEGDIVHDLM
THSGITPHIIVVQDAAHALKLLASGKHDCVLTPSKLQGEYFIKTFNLTTLHAVKTDLSQLRYCFAVRTGNRELLFKLDEG
LNILKVNGTYRRIYEKWFGIYEKEEQWGTIRYFVAALTLVGGLLLAIFLWSRSLQRQVRRRTAELVANENELRQAQAELE
QRVAERTADLAALNENLHREIAERALIEEGLCRSNQRLDLLAEMAGQLLRSESPRKAVLFLCRRVLNYLECDVFFNYLID
DQRQRLHLNACSGIGEEDVARMEWLDFGVGLCGCAARDGVRLVVNNLQDTDDQYTALVKPFGIRAYACHPLISHGRTLGT
LSFCSRTRCGFSDDDLALMKTVADHVAIAMERKKAGEQLKQRQEQLEELNRTLDRRVREEVILNRQKDLMLIRQNRQAAL
GEMLDHIAHQWKQPLNALSLIIQDLGESWSSDEPDEGNIEEAVDKTMALVEHMSQTINVFRDFYRPEKEKKVFHIKESID
RALSFIEPTLRVHSISVELDVEPGLSAFGYPKEYAQVLLNILANARDAFRTKNIQQPRMLIRACGEDDKASVTITDNAGG
IPESIIDRVFDLYFTTNEANGGSGIGLYMSKNIIEKSMGGSLEVMNTGNGTQFRIDVSIS

Sequences:

>Translated_780_residues
MRYLHIPFTKPDAKQFISLFGASLIFFIFVTSSSVWGMDRTKLIIGGDSNNLPYEVLQKGVPGGFNIELMRAVAEVMGLD
VEFRLGSWNNARRNLETGKIDVLAGMYYSEERSRQMDFSVPHTMVTPGLFVRKGSSIRSFQDLKSKQVIVQEGDIVHDLM
THSGITPHIIVVQDAAHALKLLASGKHDCVLTPSKLQGEYFIKTFNLTTLHAVKTDLSQLRYCFAVRTGNRELLFKLDEG
LNILKVNGTYRRIYEKWFGIYEKEEQWGTIRYFVAALTLVGGLLLAIFLWSRSLQRQVRRRTAELVANENELRQAQAELE
QRVAERTADLAALNENLHREIAERALIEEGLCRSNQRLDLLAEMAGQLLRSESPRKAVLFLCRRVLNYLECDVFFNYLID
DQRQRLHLNACSGIGEEDVARMEWLDFGVGLCGCAARDGVRLVVNNLQDTDDQYTALVKPFGIRAYACHPLISHGRTLGT
LSFCSRTRCGFSDDDLALMKTVADHVAIAMERKKAGEQLKQRQEQLEELNRTLDRRVREEVILNRQKDLMLIRQNRQAAL
GEMLDHIAHQWKQPLNALSLIIQDLGESWSSDEPDEGNIEEAVDKTMALVEHMSQTINVFRDFYRPEKEKKVFHIKESID
RALSFIEPTLRVHSISVELDVEPGLSAFGYPKEYAQVLLNILANARDAFRTKNIQQPRMLIRACGEDDKASVTITDNAGG
IPESIIDRVFDLYFTTNEANGGSGIGLYMSKNIIEKSMGGSLEVMNTGNGTQFRIDVSIS
>Mature_780_residues
MRYLHIPFTKPDAKQFISLFGASLIFFIFVTSSSVWGMDRTKLIIGGDSNNLPYEVLQKGVPGGFNIELMRAVAEVMGLD
VEFRLGSWNNARRNLETGKIDVLAGMYYSEERSRQMDFSVPHTMVTPGLFVRKGSSIRSFQDLKSKQVIVQEGDIVHDLM
THSGITPHIIVVQDAAHALKLLASGKHDCVLTPSKLQGEYFIKTFNLTTLHAVKTDLSQLRYCFAVRTGNRELLFKLDEG
LNILKVNGTYRRIYEKWFGIYEKEEQWGTIRYFVAALTLVGGLLLAIFLWSRSLQRQVRRRTAELVANENELRQAQAELE
QRVAERTADLAALNENLHREIAERALIEEGLCRSNQRLDLLAEMAGQLLRSESPRKAVLFLCRRVLNYLECDVFFNYLID
DQRQRLHLNACSGIGEEDVARMEWLDFGVGLCGCAARDGVRLVVNNLQDTDDQYTALVKPFGIRAYACHPLISHGRTLGT
LSFCSRTRCGFSDDDLALMKTVADHVAIAMERKKAGEQLKQRQEQLEELNRTLDRRVREEVILNRQKDLMLIRQNRQAAL
GEMLDHIAHQWKQPLNALSLIIQDLGESWSSDEPDEGNIEEAVDKTMALVEHMSQTINVFRDFYRPEKEKKVFHIKESID
RALSFIEPTLRVHSISVELDVEPGLSAFGYPKEYAQVLLNILANARDAFRTKNIQQPRMLIRACGEDDKASVTITDNAGG
IPESIIDRVFDLYFTTNEANGGSGIGLYMSKNIIEKSMGGSLEVMNTGNGTQFRIDVSIS

Specific function: Involved in a glutamine-transport system glnHPQ [H]

COG id: COG2203

COG function: function code T; FOG: GAF domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 3 family [H]

Homologues:

Organism=Escherichia coli, GI1787031, Length=252, Percent_Identity=30.5555555555556, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1788228, Length=225, Percent_Identity=25.7777777777778, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1787085, Length=198, Percent_Identity=25.7575757575758, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1787088, Length=201, Percent_Identity=29.8507462686567, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=28.5714285714286, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: 1440 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 460 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015683
- InterPro:   IPR005768
- InterPro:   IPR001638
- InterPro:   IPR018313 [H]

Pfam domain/function: PF00497 SBP_bac_3 [H]

EC number: NA

Molecular weight: Translated: 88368; Mature: 88368

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRYLHIPFTKPDAKQFISLFGASLIFFIFVTSSSVWGMDRTKLIIGGDSNNLPYEVLQKG
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHCC
VPGGFNIELMRAVAEVMGLDVEFRLGSWNNARRNLETGKIDVLAGMYYSEERSRQMDFSV
CCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHCCCCCCCEEEEECHHHHHHHHCCCCCCC
PHTMVTPGLFVRKGSSIRSFQDLKSKQVIVQEGDIVHDLMTHSGITPHIIVVQDAAHALK
CHHHHCCCCEEECCCCHHHHHHHHHCEEEEECCCHHHHHHHCCCCCCEEEEECCHHHHHH
LLASGKHDCVLTPSKLQGEYFIKTFNLTTLHAVKTDLSQLRYCFAVRTGNRELLFKLDEG
HHHCCCCCEEECHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCC
LNILKVNGTYRRIYEKWFGIYEKEEQWGTIRYFVAALTLVGGLLLAIFLWSRSLQRQVRR
CEEEEECCHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAELVANENELRQAQAELEQRVAERTADLAALNENLHREIAERALIEEGLCRSNQRLDL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LAEMAGQLLRSESPRKAVLFLCRRVLNYLECDVFFNYLIDDQRQRLHLNACSGIGEEDVA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEHHHCCCCHHHHH
RMEWLDFGVGLCGCAARDGVRLVVNNLQDTDDQYTALVKPFGIRAYACHPLISHGRTLGT
HHHHHHHCCHHHHHCCCCCHHHEECCCCCCCHHHHHHHCCCCCEEEEECHHHHCCCCEEH
LSFCSRTRCGFSDDDLALMKTVADHVAIAMERKKAGEQLKQRQEQLEELNRTLDRRVREE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILNRQKDLMLIRQNRQAALGEMLDHIAHQWKQPLNALSLIIQDLGESWSSDEPDEGNIE
HHHCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EAVDKTMALVEHMSQTINVFRDFYRPEKEKKVFHIKESIDRALSFIEPTLRVHSISVELD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE
VEPGLSAFGYPKEYAQVLLNILANARDAFRTKNIQQPRMLIRACGEDDKASVTITDNAGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCC
IPESIIDRVFDLYFTTNEANGGSGIGLYMSKNIIEKSMGGSLEVMNTGNGTQFRIDVSIS
CCHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEC
>Mature Secondary Structure
MRYLHIPFTKPDAKQFISLFGASLIFFIFVTSSSVWGMDRTKLIIGGDSNNLPYEVLQKG
CCEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCHHHHHCC
VPGGFNIELMRAVAEVMGLDVEFRLGSWNNARRNLETGKIDVLAGMYYSEERSRQMDFSV
CCCCCCHHHHHHHHHHHCCCEEEEECCCCCHHCCCCCCCEEEEECHHHHHHHHCCCCCCC
PHTMVTPGLFVRKGSSIRSFQDLKSKQVIVQEGDIVHDLMTHSGITPHIIVVQDAAHALK
CHHHHCCCCEEECCCCHHHHHHHHHCEEEEECCCHHHHHHHCCCCCCEEEEECCHHHHHH
LLASGKHDCVLTPSKLQGEYFIKTFNLTTLHAVKTDLSQLRYCFAVRTGNRELLFKLDEG
HHHCCCCCEEECHHHHCCCEEEEEECCHHHHHHHHHHHHHHHHHHEECCCCEEEEEECCC
LNILKVNGTYRRIYEKWFGIYEKEEQWGTIRYFVAALTLVGGLLLAIFLWSRSLQRQVRR
CEEEEECCHHHHHHHHHHCCCCCHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTAELVANENELRQAQAELEQRVAERTADLAALNENLHREIAERALIEEGLCRSNQRLDL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHH
LAEMAGQLLRSESPRKAVLFLCRRVLNYLECDVFFNYLIDDQRQRLHLNACSGIGEEDVA
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEHHHCCCCHHHHH
RMEWLDFGVGLCGCAARDGVRLVVNNLQDTDDQYTALVKPFGIRAYACHPLISHGRTLGT
HHHHHHHCCHHHHHCCCCCHHHEECCCCCCCHHHHHHHCCCCCEEEEECHHHHCCCCEEH
LSFCSRTRCGFSDDDLALMKTVADHVAIAMERKKAGEQLKQRQEQLEELNRTLDRRVREE
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VILNRQKDLMLIRQNRQAALGEMLDHIAHQWKQPLNALSLIIQDLGESWSSDEPDEGNIE
HHHCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
EAVDKTMALVEHMSQTINVFRDFYRPEKEKKVFHIKESIDRALSFIEPTLRVHSISVELD
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEE
VEPGLSAFGYPKEYAQVLLNILANARDAFRTKNIQQPRMLIRACGEDDKASVTITDNAGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCEEEEECCCCC
IPESIIDRVFDLYFTTNEANGGSGIGLYMSKNIIEKSMGGSLEVMNTGNGTQFRIDVSIS
CCHHHHHHHHHHHEEECCCCCCCCEEEEHHHHHHHHHCCCCEEEEECCCCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-glutamine [Periplasm]; H2O [C]

Specific reaction: ATP + L-glutamine [Periplasm] + H2O = ADP + phosphate + L-glutamine [Cytoplasm] [C]

General reaction: Translocates substrate across the membrane [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]