Click here to switch to the map view.

The map label for this gene is ribD [H]

Identifier: 118580019

GI number: 118580019

Start: 1706056

End: 1707159

Strand: Reverse

Name: ribD [H]

Synonym: Ppro_1596

Alternate gene names: 118580019

Gene position: 1707159-1706056 (Counterclockwise)

Preceding gene: 118580020

Following gene: 118580018

Centisome position: 42.59

GC content: 64.49

Gene sequence:

>1104_bases
ATGACCGACGACATCAGGCAGATGAAACGGGCCCTGGCCCTGGCACGCAGGGGGATCGGCAAGACCTCCCCCAACCCGGC
GGTGGGATGCGTCATCGTCAAGGACGGGGTCATCGTCGGCACGGGGTGGCACCGGAAGGCAGGCACCTCCCATGCTGAGA
TCCATGCCCTTGAGATGGCAGGAGAGAGCGCCCGGGGAGCCGACGTGTTTGTGACCCTGGAGCCCTGTTGTCACACCGGA
AAGACCCCCCCTTGCAGTCAGGCACTGATCCGGGCAGGGGTGAGACGGGTGGTGGCCGGCATGTCGGATCCCAACCCCCG
GGTCAGCGGCGGCGGCCTGGCCGAGCTGGAGACGGCCGGCATCCAGGTCGTCTGCGGTGTCCTTGAGAAGGAGTGCCGCG
ACCTGAACCGCCCCTTCATCAAGCAGGTCACCACCGGCATGCCCCATGTCACCTACAAGTGCGCCATGACCCTGGACGGC
AAGATCGCCACCGTGAGCGGCGCATCGCGCTGGATCAGCTGCCAGGAGTCCCGCACACTGGTTCACCGCATGCGGGCGCG
CATGGATGCAATCATGGTAGGAGTGGACACCATCATCGCCGACGACCCGCAGCTGACGGTTCGCCACGTAAGGGGCAGGA
ACCCGCTGCGGGTGGTGGTGGACACGCGCCTGCGTACCCCGGAGAGCGTCAGGGTACTCGGCGACGGCAATGCGGTCAAC
ACCCTCATCGCCACCGCGGAAACCAACCCGCGCGTGCATCTGCGCTACCAGAACCAGGGGGCCACCATCCTGGTGTGCGA
TCAGGAGAACGGCCGCGTTTCCATGAAAGACCTGATGTTCAAGCTGGGCAAACGGGGGGTGCAGTCCATCCTGCTGGAGG
GTGGAGGGCGCCTGGCCGGAAGCATGCTGGAACAGGGGCTGATCGACGAATTCGTCTTCTTCCTGGCACCCAAAATTCTG
GGAAGCGACGGTTTTTCACCGTTCAGCCTGGTGGGAAGGACAAGCATGGAGCAGGCATCCAGGCTGAACATTATCAAAGT
GAGCCGCAGCGGCATCGATATCGTCGTGCATGCGCGGTCGGAGGCGCCATGTTCACCGGCCTGA

Upstream 100 bases:

>100_bases
ACGACCTGGATGAGGTGGCCTATGTGCGCTTCGCCTCGGTATATCGTTCCTTCCGCGACATCAATGAATTCATGCAGGAG
CTGCAGGAGCTGCTGAAGAA

Downstream 100 bases:

>100_bases
TCGAAGATACCGGGCGGGTGACCGCCTTTGAACGGCGCGGCAAGGCCGGCCTGCTGCGGGTCGCGAGCTCCCTTCCCCTG
GACGAGATTGCCATCGGCGA

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 367; Mature: 366

Protein sequence:

>367_residues
MTDDIRQMKRALALARRGIGKTSPNPAVGCVIVKDGVIVGTGWHRKAGTSHAEIHALEMAGESARGADVFVTLEPCCHTG
KTPPCSQALIRAGVRRVVAGMSDPNPRVSGGGLAELETAGIQVVCGVLEKECRDLNRPFIKQVTTGMPHVTYKCAMTLDG
KIATVSGASRWISCQESRTLVHRMRARMDAIMVGVDTIIADDPQLTVRHVRGRNPLRVVVDTRLRTPESVRVLGDGNAVN
TLIATAETNPRVHLRYQNQGATILVCDQENGRVSMKDLMFKLGKRGVQSILLEGGGRLAGSMLEQGLIDEFVFFLAPKIL
GSDGFSPFSLVGRTSMEQASRLNIIKVSRSGIDIVVHARSEAPCSPA

Sequences:

>Translated_367_residues
MTDDIRQMKRALALARRGIGKTSPNPAVGCVIVKDGVIVGTGWHRKAGTSHAEIHALEMAGESARGADVFVTLEPCCHTG
KTPPCSQALIRAGVRRVVAGMSDPNPRVSGGGLAELETAGIQVVCGVLEKECRDLNRPFIKQVTTGMPHVTYKCAMTLDG
KIATVSGASRWISCQESRTLVHRMRARMDAIMVGVDTIIADDPQLTVRHVRGRNPLRVVVDTRLRTPESVRVLGDGNAVN
TLIATAETNPRVHLRYQNQGATILVCDQENGRVSMKDLMFKLGKRGVQSILLEGGGRLAGSMLEQGLIDEFVFFLAPKIL
GSDGFSPFSLVGRTSMEQASRLNIIKVSRSGIDIVVHARSEAPCSPA
>Mature_366_residues
TDDIRQMKRALALARRGIGKTSPNPAVGCVIVKDGVIVGTGWHRKAGTSHAEIHALEMAGESARGADVFVTLEPCCHTGK
TPPCSQALIRAGVRRVVAGMSDPNPRVSGGGLAELETAGIQVVCGVLEKECRDLNRPFIKQVTTGMPHVTYKCAMTLDGK
IATVSGASRWISCQESRTLVHRMRARMDAIMVGVDTIIADDPQLTVRHVRGRNPLRVVVDTRLRTPESVRVLGDGNAVNT
LIATAETNPRVHLRYQNQGATILVCDQENGRVSMKDLMFKLGKRGVQSILLEGGGRLAGSMLEQGLIDEFVFFLAPKILG
SDGFSPFSLVGRTSMEQASRLNIIKVSRSGIDIVVHARSEAPCSPA

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=367, Percent_Identity=42.2343324250681, Blast_Score=289, Evalue=2e-79,
Organism=Escherichia coli, GI145693172, Length=147, Percent_Identity=32.6530612244898, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 39492; Mature: 39361

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDDIRQMKRALALARRGIGKTSPNPAVGCVIVKDGVIVGTGWHRKAGTSHAEIHALEMA
CCHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCCHHEEEEEEC
GESARGADVFVTLEPCCHTGKTPPCSQALIRAGVRRVVAGMSDPNPRVSGGGLAELETAG
CCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCC
IQVVCGVLEKECRDLNRPFIKQVTTGMPHVTYKCAMTLDGKIATVSGASRWISCQESRTL
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEEECCEEEEECCCHHEEECHHHHHH
VHRMRARMDAIMVGVDTIIADDPQLTVRHVRGRNPLRVVVDTRLRTPESVRVLGDGNAVN
HHHHHHHHHHHHEEHHHEECCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEEECCCEEE
TLIATAETNPRVHLRYQNQGATILVCDQENGRVSMKDLMFKLGKRGVQSILLEGGGRLAG
EEEEEECCCCEEEEEECCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHH
SMLEQGLIDEFVFFLAPKILGSDGFSPFSLVGRTSMEQASRLNIIKVSRSGIDIVVHARS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHCCEEEEEECCCEEEEEEECC
EAPCSPA
CCCCCCC
>Mature Secondary Structure 
TDDIRQMKRALALARRGIGKTSPNPAVGCVIVKDGVIVGTGWHRKAGTSHAEIHALEMA
CHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECCEEECCCCCCCCCCCCHHEEEEEEC
GESARGADVFVTLEPCCHTGKTPPCSQALIRAGVRRVVAGMSDPNPRVSGGGLAELETAG
CCCCCCCEEEEEECCHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHCC
IQVVCGVLEKECRDLNRPFIKQVTTGMPHVTYKCAMTLDGKIATVSGASRWISCQESRTL
HHHHHHHHHHHHHHCCCHHHHHHHCCCCCEEEEEEEEECCEEEEECCCHHEEECHHHHHH
VHRMRARMDAIMVGVDTIIADDPQLTVRHVRGRNPLRVVVDTRLRTPESVRVLGDGNAVN
HHHHHHHHHHHHEEHHHEECCCCCEEEEECCCCCCEEEEEECCCCCCCCEEEEECCCEEE
TLIATAETNPRVHLRYQNQGATILVCDQENGRVSMKDLMFKLGKRGVQSILLEGGGRLAG
EEEEEECCCCEEEEEECCCCCEEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHCCCHHHH
SMLEQGLIDEFVFFLAPKILGSDGFSPFSLVGRTSMEQASRLNIIKVSRSGIDIVVHARS
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHCCEEEEEECCCEEEEEEECC
EAPCSPA
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8522537 [H]