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The map label for this gene is clpX

Identifier: 118579612

GI number: 118579612

Start: 1233909

End: 1235165

Strand: Reverse

Name: clpX

Synonym: Ppro_1182

Alternate gene names: 118579612

Gene position: 1235165-1233909 (Counterclockwise)

Preceding gene: 118579613

Following gene: 118579611

Centisome position: 30.82

GC content: 58.63

Gene sequence:

>1257_bases
ATGAGCCGACGGGAAACAACGCAGGAAAATCTGACCTGCTCGTTCTGCGGAAAGAGCCAGGAAGAGGTCAAGAAACTGAT
CGCCGGACCGGCGGTGTACATCTGCGACGAGTGCATCGAACTATGCAACGACATCATCGCCGAGGAACTCAAGATGGAGG
AGACCCTCGGCCCCGACTTAAAGAAGCTGCCCAAACCGCGCGAGATCAAGGATGTCCTGGACGAGTACGTCATCGGCCAG
GAAAAGGCCAAGAAAGTGCTGTCGGTGGCGGTGTACAACCACTACAAGCGCATCGAGACCAGCAACAAGCCGGGCGACGT
GGAGATGCAGAAGAGCAACATACTTCTGCTGGGCCCCACCGGTTCGGGTAAGACGCTCCTGGCCCAGACACTGGCGCGCA
TCCTCAAGGTCCCCTTTGCCATGGCCGACGCCACCAACCTCACCGAGGCGGGCTACGTGGGCGAGGATGTGGAGAACATC
ATCTTAAGCCTGCTGCAGGCAGCCGACTATGACGTGGAGCGAGCCCAGAAGGGGATCATCTACATCGACGAAATCGACAA
GATCGCCCGAAAGAGCGAGTCACCTTCCCTCACCCGCGACGTTTCCGGCGAGGGAGTTCAGCAGGCGCTCTTGAAGATCA
TCGAGGGGACCGTCGCCAGCATCCCGCCCAAGGGTGGACGCAAGCATCCCCAGCAGGAATTCATGAAGGTGGACACGACC
AACATCCTCTTCATCTGCGGCGGCGCGTTTGCCGGACTTGACAGCGTCATCCAGCAGCGTATCGGCATGAAGAGCCTGGG
TTTCGGCGCCGATGTCAAGAAGCGGGCTGAGAAGAAACTGGGCGAACTGCTGCTCAACGTCACCCCGGACGACCTGCTGA
AATACGGCTACATCCCGGAGTTCATCGGCAGGCTGCCCATGCTGGCCACCCTCACCGAACTGGACGAGGACGCCATGGTG
CAGATCCTCAAGGAGCCGAAGAACTCCCTGGTCAAGCAGTACCAGAAGCTGTTCGAACTGGAGAACGTGCGCCTTCGCTT
TACCGACGGCTCCCTGGTGGCCATTGCCCGGGAGGCCCTCAAGCGCAATACCGGTGCCCGGGGGTTGCGCTCCATACTTG
AGAACTCCATGCTTGACATCATGTACGAAGTGCCGTCACAGCCCAATGTCAAGGAAGTGGTCATCAGCGAAGAAGTGATC
TACCACAAGGAAAAACCGATCGTCGTCTATGAACAACAGGTAAGCGACGCCGCCTAA

Upstream 100 bases:

>100_bases
CGGATACGGACCGCGACTACTTCATGTCAGCGACCGAAGCAGAGGAGTACGGACTGATCGACGCAACCTTCACCAGAAAG
CCTGACAGCGGAGGCACTCC

Downstream 100 bases:

>100_bases
CCTGAACTGCGAACCTGTCATTTTCCCTCTCCTTTCCATCAAGGCCAGGGAAAATGACACACAACCCGCGGTACCCCATG
AAATGTGGATTCGCCAGACA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MSRRETTQENLTCSFCGKSQEEVKKLIAGPAVYICDECIELCNDIIAEELKMEETLGPDLKKLPKPREIKDVLDEYVIGQ
EKAKKVLSVAVYNHYKRIETSNKPGDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENI
ILSLLQAADYDVERAQKGIIYIDEIDKIARKSESPSLTRDVSGEGVQQALLKIIEGTVASIPPKGGRKHPQQEFMKVDTT
NILFICGGAFAGLDSVIQQRIGMKSLGFGADVKKRAEKKLGELLLNVTPDDLLKYGYIPEFIGRLPMLATLTELDEDAMV
QILKEPKNSLVKQYQKLFELENVRLRFTDGSLVAIAREALKRNTGARGLRSILENSMLDIMYEVPSQPNVKEVVISEEVI
YHKEKPIVVYEQQVSDAA

Sequences:

>Translated_418_residues
MSRRETTQENLTCSFCGKSQEEVKKLIAGPAVYICDECIELCNDIIAEELKMEETLGPDLKKLPKPREIKDVLDEYVIGQ
EKAKKVLSVAVYNHYKRIETSNKPGDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENI
ILSLLQAADYDVERAQKGIIYIDEIDKIARKSESPSLTRDVSGEGVQQALLKIIEGTVASIPPKGGRKHPQQEFMKVDTT
NILFICGGAFAGLDSVIQQRIGMKSLGFGADVKKRAEKKLGELLLNVTPDDLLKYGYIPEFIGRLPMLATLTELDEDAMV
QILKEPKNSLVKQYQKLFELENVRLRFTDGSLVAIAREALKRNTGARGLRSILENSMLDIMYEVPSQPNVKEVVISEEVI
YHKEKPIVVYEQQVSDAA
>Mature_417_residues
SRRETTQENLTCSFCGKSQEEVKKLIAGPAVYICDECIELCNDIIAEELKMEETLGPDLKKLPKPREIKDVLDEYVIGQE
KAKKVLSVAVYNHYKRIETSNKPGDVEMQKSNILLLGPTGSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENII
LSLLQAADYDVERAQKGIIYIDEIDKIARKSESPSLTRDVSGEGVQQALLKIIEGTVASIPPKGGRKHPQQEFMKVDTTN
ILFICGGAFAGLDSVIQQRIGMKSLGFGADVKKRAEKKLGELLLNVTPDDLLKYGYIPEFIGRLPMLATLTELDEDAMVQ
ILKEPKNSLVKQYQKLFELENVRLRFTDGSLVAIAREALKRNTGARGLRSILENSMLDIMYEVPSQPNVKEVVISEEVIY
HKEKPIVVYEQQVSDAA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=324, Percent_Identity=50.3086419753086, Blast_Score=301, Evalue=8e-82,
Organism=Escherichia coli, GI1786642, Length=412, Percent_Identity=66.0194174757282, Blast_Score=558, Evalue=1e-160,
Organism=Escherichia coli, GI1790366, Length=103, Percent_Identity=43.6893203883495, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=329, Percent_Identity=45.2887537993921, Blast_Score=276, Evalue=2e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=329, Percent_Identity=45.2887537993921, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=431, Percent_Identity=37.122969837587, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71988660, Length=258, Percent_Identity=38.3720930232558, Blast_Score=169, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=41.92037470726, Blast_Score=283, Evalue=5e-77,
Organism=Drosophila melanogaster, GI24648291, Length=316, Percent_Identity=46.2025316455696, Blast_Score=282, Evalue=3e-76,
Organism=Drosophila melanogaster, GI24648289, Length=316, Percent_Identity=46.2025316455696, Blast_Score=282, Evalue=4e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_PELPD (A1AN84)

Other databases:

- EMBL:   CP000482
- RefSeq:   YP_900862.1
- ProteinModelPortal:   A1AN84
- STRING:   A1AN84
- GeneID:   4574652
- GenomeReviews:   CP000482_GR
- KEGG:   ppd:Ppro_1182
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   A1AN84
- ProtClustDB:   PRK05342
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 46460; Mature: 46329

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRETTQENLTCSFCGKSQEEVKKLIAGPAVYICDECIELCNDIIAEELKMEETLGPDL
CCCCCCCHHCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KKLPKPREIKDVLDEYVIGQEKAKKVLSVAVYNHYKRIETSNKPGDVEMQKSNILLLGPT
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCC
GSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENIILSLLQAADYDVERAQKGII
CCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKIARKSESPSLTRDVSGEGVQQALLKIIEGTVASIPPKGGRKHPQQEFMKVDTT
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDSVIQQRIGMKSLGFGADVKKRAEKKLGELLLNVTPDDLLKYGYIPE
CEEEEECCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
FIGRLPMLATLTELDEDAMVQILKEPKNSLVKQYQKLFELENVRLRFTDGSLVAIAREAL
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH
KRNTGARGLRSILENSMLDIMYEVPSQPNVKEVVISEEVIYHKEKPIVVYEQQVSDAA
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC
>Mature Secondary Structure 
SRRETTQENLTCSFCGKSQEEVKKLIAGPAVYICDECIELCNDIIAEELKMEETLGPDL
CCCCCCHHCCEEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
KKLPKPREIKDVLDEYVIGQEKAKKVLSVAVYNHYKRIETSNKPGDVEMQKSNILLLGPT
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCEEEECCC
GSGKTLLAQTLARILKVPFAMADATNLTEAGYVGEDVENIILSLLQAADYDVERAQKGII
CCCHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHCCCE
YIDEIDKIARKSESPSLTRDVSGEGVQQALLKIIEGTVASIPPKGGRKHPQQEFMKVDTT
EEHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCC
NILFICGGAFAGLDSVIQQRIGMKSLGFGADVKKRAEKKLGELLLNVTPDDLLKYGYIPE
CEEEEECCHHHHHHHHHHHHCCCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCHH
FIGRLPMLATLTELDEDAMVQILKEPKNSLVKQYQKLFELENVRLRFTDGSLVAIAREAL
HHHCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHH
KRNTGARGLRSILENSMLDIMYEVPSQPNVKEVVISEEVIYHKEKPIVVYEQQVSDAA
HHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA