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The map label for this gene is pepQ [H]

Identifier: 118579567

GI number: 118579567

Start: 1178140

End: 1179336

Strand: Reverse

Name: pepQ [H]

Synonym: Ppro_1135

Alternate gene names: 118579567

Gene position: 1179336-1178140 (Counterclockwise)

Preceding gene: 118579568

Following gene: 118579566

Centisome position: 29.42

GC content: 62.57

Gene sequence:

>1197_bases
ATGCGACTGACACCCGCCAGCGAGCTTGCGCAACGCTGCAAGAAACTTCAGCAGTACATGACCCAGGAAGGCCTGGACGC
CGTCATCATCGCCCAGAATGCCGACCTATTCTACTTTAGCGGCACCATCCAGAGCGGCAACCTGTACATCCCCGCCCAGG
GCGAACCGCTGTACATGGTACGCAAGGACCATGGCCGCGCCCGCAGGGAATCGGCGCTCCAGGAGATCATCCCCTTCGGC
TCCATGAGGGACATTCCCGCCCGACTGGCCGAGTACGGCTACCCCACACCCGGCCGGATCGGCCTGGAGCTGGACGTGCT
GCCGGTGAACTTCTACGAACGATTCCGCAAGACATTCCCCGGTGCGGCTTTCACGGACGCCACCCCGCTGATCCGGCGCG
TGCGCATGATCAAGTCCCCCTACGAACTGGAGATCATGAGAGCAGCGGCCAACCAGCAGGACGCCATCTTCCAGCGCGCC
AAAGAGGTCATCCGCGAGGGGATCAGCGAACTGGAACTGGCTGCCGAGTTGGAGTGCTGCGCACGGAAACTGGGGCACCA
GGGACTGATCCGCATGCGTGGCTTTAACTCGGAACTGTTCTATGCCCACATCTTCTCCGGCCCGGACAGCGCGATCCCGG
CCTACGCCGACACGCCACTGGGAGGGCCGGGGCTGAACCCCTCCTTCGGACAGGGACCGGGACACAAAGCGATCTCACGG
GATGAGGCGATCATCGTGGATTTCGGCGCCTGCGCTGACGGCTATTTAAGCGACCAGACCCGCGTCTTCGCCATCAATTC
CCTGCCGGCCAGGCTGCGCAAGGGGTATGACGACATGCGCAAGGTCCAGGAACGGATGATGGCCATCGCCACCCCCGGCG
TCCCCTGGGGAGCGGTCTATGGCGAATGCCTGAGCCTGGCCATCGAGATGGGCTATGCCGACAGCTTTATGGGCGCTGCC
GGATCCCAGGTCTCCTTTATCGGTCACGGCGTGGGAATTGAAATCGACGAGTACCCCTTCATCGCCCGAGGATTCGACGA
CATGGCAATGGAGAACGGGATGGTCTTTGCATTCGAGCCCAAGGTCGTCTTCCCCGGCCAGGGGGCCGTTGGCATCGAGA
ACACCTTCCATCTGGATCAGGGAGTGGTTAAACAGCTGACCTGCTCCAGCGAGGAGCCGGTCATCCTGGCCGGCTGA

Upstream 100 bases:

>100_bases
GTCGTCGCTCCATCTCCGCATAACCGCGGGGAGCGGTTTTGAACAGTGGCACACCGACGTGCGTCGCAGGCGACCACGAT
GAAAAGGAGCAAAAAATAAC

Downstream 100 bases:

>100_bases
CCGACTCACCCGCGTCCGCGCCGCGACCGCCGGCCGATGCCGACCGGTAGTTTGTCTGGTATACTTTCCCCGTCTTCAGG
AAGCAGGGGCGTGCCAGCAA

Product: peptidase M24

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRLTPASELAQRCKKLQQYMTQEGLDAVIIAQNADLFYFSGTIQSGNLYIPAQGEPLYMVRKDHGRARRESALQEIIPFG
SMRDIPARLAEYGYPTPGRIGLELDVLPVNFYERFRKTFPGAAFTDATPLIRRVRMIKSPYELEIMRAAANQQDAIFQRA
KEVIREGISELELAAELECCARKLGHQGLIRMRGFNSELFYAHIFSGPDSAIPAYADTPLGGPGLNPSFGQGPGHKAISR
DEAIIVDFGACADGYLSDQTRVFAINSLPARLRKGYDDMRKVQERMMAIATPGVPWGAVYGECLSLAIEMGYADSFMGAA
GSQVSFIGHGVGIEIDEYPFIARGFDDMAMENGMVFAFEPKVVFPGQGAVGIENTFHLDQGVVKQLTCSSEEPVILAG

Sequences:

>Translated_398_residues
MRLTPASELAQRCKKLQQYMTQEGLDAVIIAQNADLFYFSGTIQSGNLYIPAQGEPLYMVRKDHGRARRESALQEIIPFG
SMRDIPARLAEYGYPTPGRIGLELDVLPVNFYERFRKTFPGAAFTDATPLIRRVRMIKSPYELEIMRAAANQQDAIFQRA
KEVIREGISELELAAELECCARKLGHQGLIRMRGFNSELFYAHIFSGPDSAIPAYADTPLGGPGLNPSFGQGPGHKAISR
DEAIIVDFGACADGYLSDQTRVFAINSLPARLRKGYDDMRKVQERMMAIATPGVPWGAVYGECLSLAIEMGYADSFMGAA
GSQVSFIGHGVGIEIDEYPFIARGFDDMAMENGMVFAFEPKVVFPGQGAVGIENTFHLDQGVVKQLTCSSEEPVILAG
>Mature_398_residues
MRLTPASELAQRCKKLQQYMTQEGLDAVIIAQNADLFYFSGTIQSGNLYIPAQGEPLYMVRKDHGRARRESALQEIIPFG
SMRDIPARLAEYGYPTPGRIGLELDVLPVNFYERFRKTFPGAAFTDATPLIRRVRMIKSPYELEIMRAAANQQDAIFQRA
KEVIREGISELELAAELECCARKLGHQGLIRMRGFNSELFYAHIFSGPDSAIPAYADTPLGGPGLNPSFGQGPGHKAISR
DEAIIVDFGACADGYLSDQTRVFAINSLPARLRKGYDDMRKVQERMMAIATPGVPWGAVYGECLSLAIEMGYADSFMGAA
GSQVSFIGHGVGIEIDEYPFIARGFDDMAMENGMVFAFEPKVVFPGQGAVGIENTFHLDQGVVKQLTCSSEEPVILAG

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788728, Length=259, Percent_Identity=30.1158301158301, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 43717; Mature: 43717

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTPASELAQRCKKLQQYMTQEGLDAVIIAQNADLFYFSGTIQSGNLYIPAQGEPLYMV
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCCEEEECCCCEEEEE
RKDHGRARRESALQEIIPFGSMRDIPARLAEYGYPTPGRIGLELDVLPVNFYERFRKTFP
ECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHCC
GAAFTDATPLIRRVRMIKSPYELEIMRAAANQQDAIFQRAKEVIREGISELELAAELECC
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARKLGHQGLIRMRGFNSELFYAHIFSGPDSAIPAYADTPLGGPGLNPSFGQGPGHKAISR
HHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEAIIVDFGACADGYLSDQTRVFAINSLPARLRKGYDDMRKVQERMMAIATPGVPWGAVY
CCEEEEEECCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHH
GECLSLAIEMGYADSFMGAAGSQVSFIGHGVGIEIDEYPFIARGFDDMAMENGMVFAFEP
HHHHHHHHHCCCCHHHHCCCCCEEEEEECCCCEEECCCCCCCCCCHHHHHCCCEEEEECC
KVVFPGQGAVGIENTFHLDQGVVKQLTCSSEEPVILAG
CEEECCCCCCCCCCEEECCHHHHHHHHCCCCCCEEEEC
>Mature Secondary Structure
MRLTPASELAQRCKKLQQYMTQEGLDAVIIAQNADLFYFSGTIQSGNLYIPAQGEPLYMV
CCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEEECCCCEEEECCCCEEEEE
RKDHGRARRESALQEIIPFGSMRDIPARLAEYGYPTPGRIGLELDVLPVNFYERFRKTFP
ECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCEEEEEEEEECHHHHHHHHHCC
GAAFTDATPLIRRVRMIKSPYELEIMRAAANQQDAIFQRAKEVIREGISELELAAELECC
CCCCCCHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARKLGHQGLIRMRGFNSELFYAHIFSGPDSAIPAYADTPLGGPGLNPSFGQGPGHKAISR
HHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
DEAIIVDFGACADGYLSDQTRVFAINSLPARLRKGYDDMRKVQERMMAIATPGVPWGAVY
CCEEEEEECCCCCCCCCCCEEEEEECCCHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHHH
GECLSLAIEMGYADSFMGAAGSQVSFIGHGVGIEIDEYPFIARGFDDMAMENGMVFAFEP
HHHHHHHHHCCCCHHHHCCCCCEEEEEECCCCEEECCCCCCCCCCHHHHHCCCEEEEECC
KVVFPGQGAVGIENTFHLDQGVVKQLTCSSEEPVILAG
CEEECCCCCCCCCCEEECCHHHHHHHHCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]