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The map label for this gene is murQ [H]

Identifier: 118476480

GI number: 118476480

Start: 856952

End: 857866

Strand: Direct

Name: murQ [H]

Synonym: BALH_0745

Alternate gene names: 118476480

Gene position: 856952-857866 (Clockwise)

Preceding gene: 118476479

Following gene: 118476481

Centisome position: 16.3

GC content: 38.8

Gene sequence:

>915_bases
ATGAAATTAAATTTCAAAGCAGGTGGGAATATGTTAGAGAATTTATCGACAGAACATCGCAATGAGAAGACGATGAATTT
AGATGAGATGAACATAAAAGAAGTTCTGCAAAGTATGAATGAAGAAGATCGAACTGTTGCATTAGCAGTTGAAAAAGAGA
TAGAACATATTGAAAAGGTTGTGCGGGTTGTTATTCAATCTTTTGAAGAAGAGGGCCGATTAATTTACATTGGGGCTGGC
ACGAGTGGCCGTTTAGGTATTTTGGACGCAGTGGAATGCCCGCCGACATTTGGGACAGATGATAAAATGGTGCAAGGATT
TATAGCAGGTGGATTGAAAGCGTTTACTAAAGCGGTGGAAGGTGCCGAAGATCGCGAAGAGTTAGCAGAAGAAGATTTAA
AAAGTATTGGATTAAACGAGAAAGATACTGTAATTGGAATTGCGGCAAGTGGCCGAACTCCTTATGTAATTGGCGGCTTG
AAGTACGCGAATAGCGTAGGAGCGAGTACAGCTAGTATCTCTTGTAATAAAAATGCTGAAATAAGTAAATATGCAAAACT
AAATGTGGAAGTAGAAACAGGCGCAGAAATTTTAACAGGTTCAACGCGGTTGAAGGCTGGTACAGCGCAAAAATTAGTAC
TGAATATGATTTCAACAGCTTCTATGATTGGTGTTGGAAAAGTATATAAAAATTTAATGGTAGATGTGCAATCTACGAAT
GAAAAGTTAGTAGAACGATCAAAACGAATTATTGTGGAAGCAACAGGGGTTAGTTATGAAGTAGCAGCAGAGCATTATGA
AAAAGCAGAACGTAACGTAAAAGCTGCGATTGTTATGGTGCTATTGCAGTGTGAGTATGGGGAAGCACTGGAGAAACTAA
AAGAAGCGAAAGGGTTTGTGAAGAAGGCACTATAA

Upstream 100 bases:

>100_bases
TTGGATACGGACGGACATAAATTCGTCATGAAAAGAAATTAAATTTCATAAAATAATAAAGTGATATTGATTTTAAATTT
CTTGAAGTTATAATGAAAGT

Downstream 100 bases:

>100_bases
ATAATAGGGAGGGGGATTCTATTATGAGGAAAGAAGAGAGAATGGCGAAAGAAATTTCGGAGCAACTTGGGGGAGTAAAA
AATATTCGCGGTATTGCTCA

Product: N-acetylmuramic acid-6-phosphate etherase

Products: NA

Alternate protein names: MurNAc-6-P etherase; N-acetylmuramic acid 6-phosphate hydrolase; N-acetylmuramic acid 6-phosphate lyase [H]

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKLNFKAGGNMLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAG
TSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGL
KYANSVGASTASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTN
EKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKEAKGFVKKAL

Sequences:

>Translated_304_residues
MKLNFKAGGNMLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAG
TSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGL
KYANSVGASTASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTN
EKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKEAKGFVKKAL
>Mature_304_residues
MKLNFKAGGNMLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKVVRVVIQSFEEEGRLIYIGAG
TSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVEGAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGL
KYANSVGASTASISCNKNAEISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTN
EKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKEAKGFVKKAL

Specific function: Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate [H]

COG id: COG2103

COG function: function code R; Predicted sugar phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788768, Length=293, Percent_Identity=50.5119453924915, Blast_Score=278, Evalue=3e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005486
- InterPro:   IPR005488
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 33041; Mature: 33041

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS01272 GCKR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLNFKAGGNMLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKV
CEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHH
VRVVIQSFEEEGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVE
HHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAE
CCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECHHHHHHCCCCCEEEECCCCCC
ISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTN
CCEEEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKEAKGFV
HHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KKAL
HHCC
>Mature Secondary Structure
MKLNFKAGGNMLENLSTEHRNEKTMNLDEMNIKEVLQSMNEEDRTVALAVEKEIEHIEKV
CEEECCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCEEEEHHHHHHHHHHHH
VRVVIQSFEEEGRLIYIGAGTSGRLGILDAVECPPTFGTDDKMVQGFIAGGLKAFTKAVE
HHHHHHHHHHCCCEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHC
GAEDREELAEEDLKSIGLNEKDTVIGIAASGRTPYVIGGLKYANSVGASTASISCNKNAE
CCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEECHHHHHHCCCCCEEEECCCCCC
ISKYAKLNVEVETGAEILTGSTRLKAGTAQKLVLNMISTASMIGVGKVYKNLMVDVQSTN
CCEEEEEEEEEECCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKLVERSKRIIVEATGVSYEVAAEHYEKAERNVKAAIVMVLLQCEYGEALEKLKEAKGFV
HHHHHHCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
KKAL
HHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA