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The map label for this gene is scrA [H]

Identifier: 118476481

GI number: 118476481

Start: 857890

End: 859254

Strand: Direct

Name: scrA [H]

Synonym: BALH_0746

Alternate gene names: 118476481

Gene position: 857890-859254 (Clockwise)

Preceding gene: 118476480

Following gene: 118476482

Centisome position: 16.32

GC content: 41.03

Gene sequence:

>1365_bases
ATGAGGAAAGAAGAGAGAATGGCGAAAGAAATTTCGGAGCAACTTGGGGGAGTAAAAAATATTCGCGGTATTGCTCATTG
TATGACGAGACTGCGATTAACGCTTCATGATGAAAGTAAAGTAAACATGGACCTTTTAAAAAAGGTTGAAGGGGTTATGG
GCGTTATTGAAGATGAGACGCTTCAAGTTGTCGTTGGTCCAGGAACGGTAAATAAAGTAGCAGCAGAGATGGAAGGTTTA
ACGGGACTGCGAATTGGTGAGGTGGCAGATCATCACCTTGAAGATCTTGGGCAAGAGATGAAGTCAGAGATTAAGAAGAA
AAATAATACACCGGTGAAAAACTTTTTAAGAAAAATAGGAAGTATTTTCATTCCGTTAATTCCGGGTCTTGTTGCGTCAG
GTATTATAAACGGGGTTGCTAACTTTGCGAAAAACGCAGGTGCTGATCCGAATGCAACATGGCTACAAATGTTACTACTT
ATTGGCGGCGGTATCTTTACATTCTTAGGAATTTTAGTGGGCTGGAATACAGCGAAAGAGTTTGGCGGGACACCAGTTCT
TGGGGCAATTGCTGGTATTTTAATTTTCAATCCGGCGATGGCGAACGTAAAGTTATTTGGTGAAGCGCTCGTACCCGGAC
GGGGCGGATTGTTTGCAGTTATTTTTGCAGCGTGGCTTATGGTTGTAGTGGAAAGACAAGTTCGAAAAGCTGTACCAAAT
GCAGTTGATATTATTATAACACCACTCATTACTGTGTTAGTCGTAAGTATCGTAACGATGTTAGCAATTCAGCCGGTAGC
AGGTTTCTTATCTGAAGGAATTACAAACGGAATTAATGGCATTTTAAATATTGGCGGAGCGTTTGCGGGAGCAGTACTTG
CTGGAACATTTTTACCGCTCGTTATGGTCGGATTACATCACGGTTTAACACCGATTCACATGGAGTTTATTAATCAAACG
CACGTAACACCTTTATTACCGGTACTTGCAATGGCCGGCGCTGGGCAAGTAGGAGCAGCGATTGCTATTTTTGTAAAAAC
AAAAAACAAACGACTTCGTAACGTAATTAAAGGGGCATTACCAGTTGGATTTTTAGGGATTGGTGAACCGTTATTATACG
GGGTTACATTACCACTGGGAAAACCGTTTCTTACAGCTTGTTTAGGAGCAGCTGTCGGCGGTGCGTTCCAAGCAGTTATG
AAAACAGCTGCACTCGGAATTGGTGTATCAGGATTATCATTAATTCCGTTAATTGCTGATAATAAATATTTATTATATTT
CCTTGGATTAGTGGTGGCATATACTTTCGGATTCATCTTTACGTACTTCTTCGGATTTAAAGAAGAAATGGCAGAAAACA
TATAG

Upstream 100 bases:

>100_bases
TGCTATTGCAGTGTGAGTATGGGGAAGCACTGGAGAAACTAAAAGAAGCGAAAGGGTTTGTGAAGAAGGCACTATAAATA
ATAGGGAGGGGGATTCTATT

Downstream 100 bases:

>100_bases
AGAAAGGGATTCCTTTCTCTTTTTCTATCATGCCTTTCGAGAGGACTCCCACTTCTAAACGTAAGTGAAGGTGGTGAGGT
GAATCGAAAGAAATATTTTA

Product: PTS system sucrose-specific transporter subunit IIBC

Products: NA

Alternate protein names: Phosphotransferase enzyme IIB component; PTS system EIIB component; Permease IIC component; PTS system EIIC component [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MRKEERMAKEISEQLGGVKNIRGIAHCMTRLRLTLHDESKVNMDLLKKVEGVMGVIEDETLQVVVGPGTVNKVAAEMEGL
TGLRIGEVADHHLEDLGQEMKSEIKKKNNTPVKNFLRKIGSIFIPLIPGLVASGIINGVANFAKNAGADPNATWLQMLLL
IGGGIFTFLGILVGWNTAKEFGGTPVLGAIAGILIFNPAMANVKLFGEALVPGRGGLFAVIFAAWLMVVVERQVRKAVPN
AVDIIITPLITVLVVSIVTMLAIQPVAGFLSEGITNGINGILNIGGAFAGAVLAGTFLPLVMVGLHHGLTPIHMEFINQT
HVTPLLPVLAMAGAGQVGAAIAIFVKTKNKRLRNVIKGALPVGFLGIGEPLLYGVTLPLGKPFLTACLGAAVGGAFQAVM
KTAALGIGVSGLSLIPLIADNKYLLYFLGLVVAYTFGFIFTYFFGFKEEMAENI

Sequences:

>Translated_454_residues
MRKEERMAKEISEQLGGVKNIRGIAHCMTRLRLTLHDESKVNMDLLKKVEGVMGVIEDETLQVVVGPGTVNKVAAEMEGL
TGLRIGEVADHHLEDLGQEMKSEIKKKNNTPVKNFLRKIGSIFIPLIPGLVASGIINGVANFAKNAGADPNATWLQMLLL
IGGGIFTFLGILVGWNTAKEFGGTPVLGAIAGILIFNPAMANVKLFGEALVPGRGGLFAVIFAAWLMVVVERQVRKAVPN
AVDIIITPLITVLVVSIVTMLAIQPVAGFLSEGITNGINGILNIGGAFAGAVLAGTFLPLVMVGLHHGLTPIHMEFINQT
HVTPLLPVLAMAGAGQVGAAIAIFVKTKNKRLRNVIKGALPVGFLGIGEPLLYGVTLPLGKPFLTACLGAAVGGAFQAVM
KTAALGIGVSGLSLIPLIADNKYLLYFLGLVVAYTFGFIFTYFFGFKEEMAENI
>Mature_454_residues
MRKEERMAKEISEQLGGVKNIRGIAHCMTRLRLTLHDESKVNMDLLKKVEGVMGVIEDETLQVVVGPGTVNKVAAEMEGL
TGLRIGEVADHHLEDLGQEMKSEIKKKNNTPVKNFLRKIGSIFIPLIPGLVASGIINGVANFAKNAGADPNATWLQMLLL
IGGGIFTFLGILVGWNTAKEFGGTPVLGAIAGILIFNPAMANVKLFGEALVPGRGGLFAVIFAAWLMVVVERQVRKAVPN
AVDIIITPLITVLVVSIVTMLAIQPVAGFLSEGITNGINGILNIGGAFAGAVLAGTFLPLVMVGLHHGLTPIHMEFINQT
HVTPLLPVLAMAGAGQVGAAIAIFVKTKNKRLRNVIKGALPVGFLGIGEPLLYGVTLPLGKPFLTACLGAAVGGAFQAVM
KTAALGIGVSGLSLIPLIADNKYLLYFLGLVVAYTFGFIFTYFFGFKEEMAENI

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788769, Length=480, Percent_Identity=39.375, Blast_Score=271, Evalue=5e-74,
Organism=Escherichia coli, GI1790159, Length=424, Percent_Identity=30.4245283018868, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI2367362, Length=431, Percent_Identity=25.754060324826, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI48994906, Length=478, Percent_Identity=27.6150627615063, Blast_Score=122, Evalue=4e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 48035; Mature: 48035

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKEERMAKEISEQLGGVKNIRGIAHCMTRLRLTLHDESKVNMDLLKKVEGVMGVIEDET
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
LQVVVGPGTVNKVAAEMEGLTGLRIGEVADHHLEDLGQEMKSEIKKKNNTPVKNFLRKIG
EEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SIFIPLIPGLVASGIINGVANFAKNAGADPNATWLQMLLLIGGGIFTFLGILVGWNTAKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHH
FGGTPVLGAIAGILIFNPAMANVKLFGEALVPGRGGLFAVIFAAWLMVVVERQVRKAVPN
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
AVDIIITPLITVLVVSIVTMLAIQPVAGFLSEGITNGINGILNIGGAFAGAVLAGTFLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMVGLHHGLTPIHMEFINQTHVTPLLPVLAMAGAGQVGAAIAIFVKTKNKRLRNVIKGAL
HHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHC
PVGFLGIGEPLLYGVTLPLGKPFLTACLGAAVGGAFQAVMKTAALGIGVSGLSLIPLIAD
CCCHHCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEC
NKYLLYFLGLVVAYTFGFIFTYFFGFKEEMAENI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRKEERMAKEISEQLGGVKNIRGIAHCMTRLRLTLHDESKVNMDLLKKVEGVMGVIEDET
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCC
LQVVVGPGTVNKVAAEMEGLTGLRIGEVADHHLEDLGQEMKSEIKKKNNTPVKNFLRKIG
EEEEECCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
SIFIPLIPGLVASGIINGVANFAKNAGADPNATWLQMLLLIGGGIFTFLGILVGWNTAKE
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHH
FGGTPVLGAIAGILIFNPAMANVKLFGEALVPGRGGLFAVIFAAWLMVVVERQVRKAVPN
CCCCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
AVDIIITPLITVLVVSIVTMLAIQPVAGFLSEGITNGINGILNIGGAFAGAVLAGTFLPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VMVGLHHGLTPIHMEFINQTHVTPLLPVLAMAGAGQVGAAIAIFVKTKNKRLRNVIKGAL
HHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHC
PVGFLGIGEPLLYGVTLPLGKPFLTACLGAAVGGAFQAVMKTAALGIGVSGLSLIPLIAD
CCCHHCCCCHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEC
NKYLLYFLGLVVAYTFGFIFTYFFGFKEEMAENI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]