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The map label for this gene is hexR [C]

Identifier: 118476479

GI number: 118476479

Start: 855963

End: 856826

Strand: Direct

Name: hexR [C]

Synonym: BALH_0744

Alternate gene names: 118476479

Gene position: 855963-856826 (Clockwise)

Preceding gene: 118476478

Following gene: 118476480

Centisome position: 16.28

GC content: 38.08

Gene sequence:

>864_bases
GTGAAAGCTTCAACATTACTATTTAAAATTGAAAGTAATATGGATCAATTTTCACCAGCTGAAAAGAAGGTTGCCATATA
CATAATGGAGAATGCAGAGATTGTTCCGAACTTAACGACGAAAGAAGTGTCAACGAATGCAGGCGCAAGTGAGGCGAGTG
TTGTTCGCTTTTGTAAGTCGATTGGGATTGGGAGCTTTAAAGCATTTAAAATCGCGCTCGTTCGTGAATTAACGATTGCT
GATTATAATATTAATGATTTTTCAGTGATGAATACGGAAGATGGACCGTATGACTTGTTTAATAAAGTTACATATGTGAA
TAAAGCTGCAATTGAGGCGAGCGTTACGGCGATAGATAAGAAGGAGCTTGAGAAAGCTGCAGATCGTATTGTAAATGCGG
ATAAAATTATCTTTTACGGAGTAGGTGGATCAGCAACTCCGGCGATGGACGGGGCTTATAAATTTACAAGGCTCGGATTC
ACTGCAATGATGCTATCTGATTTTCATATGATGTTACCACTTGTGACAAATTTAAAAGAAGGCGATATATTTGTTGCGAT
TTCAACATCTGGTCGCACGAAAGATGTACTTGAAATGGCGCAATATGCGAAGAGACAAGGTGCAACAGTTATTGCGATTA
CGAAGCTTGATCAATCATCGCCGTTATATAAAGAGGCGGATATTCGTCTTTGTATGCCAGATGTAGAACAAGATCATCGT
ATTGCAAGTATTGCTTCAAGAATGACGCAATTGAACATGATAGATGCTTTATATGTTATTACCTTTAATCGTATTGGTAA
TAAAGTGCTGGATCAATTTATGGAAACAAGAGAAGAAGCTTTGCGATTACGGAAGCTGAAATGA

Upstream 100 bases:

>100_bases
GCATTGTAAATGTGTTTCATCCTCCTGGCGATGATGGTTTTTACCTTCTTGAAGCAAGAGAAAATCAGTGAACGCAACCG
TAAGAAGTGGAGGTTAAATA

Downstream 100 bases:

>100_bases
GAAGATGGGGAAACCCATCTTTTTTTTGGATACGGACGGACATAAATTCGTCATGAAAAGAAATTAAATTTCATAAAATA
ATAAAGTGATATTGATTTTA

Product: RpiR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKASTLLFKIESNMDQFSPAEKKVAIYIMENAEIVPNLTTKEVSTNAGASEASVVRFCKSIGIGSFKAFKIALVRELTIA
DYNINDFSVMNTEDGPYDLFNKVTYVNKAAIEASVTAIDKKELEKAADRIVNADKIIFYGVGGSATPAMDGAYKFTRLGF
TAMMLSDFHMMLPLVTNLKEGDIFVAISTSGRTKDVLEMAQYAKRQGATVIAITKLDQSSPLYKEADIRLCMPDVEQDHR
IASIASRMTQLNMIDALYVITFNRIGNKVLDQFMETREEALRLRKLK

Sequences:

>Translated_287_residues
MKASTLLFKIESNMDQFSPAEKKVAIYIMENAEIVPNLTTKEVSTNAGASEASVVRFCKSIGIGSFKAFKIALVRELTIA
DYNINDFSVMNTEDGPYDLFNKVTYVNKAAIEASVTAIDKKELEKAADRIVNADKIIFYGVGGSATPAMDGAYKFTRLGF
TAMMLSDFHMMLPLVTNLKEGDIFVAISTSGRTKDVLEMAQYAKRQGATVIAITKLDQSSPLYKEADIRLCMPDVEQDHR
IASIASRMTQLNMIDALYVITFNRIGNKVLDQFMETREEALRLRKLK
>Mature_287_residues
MKASTLLFKIESNMDQFSPAEKKVAIYIMENAEIVPNLTTKEVSTNAGASEASVVRFCKSIGIGSFKAFKIALVRELTIA
DYNINDFSVMNTEDGPYDLFNKVTYVNKAAIEASVTAIDKKELEKAADRIVNADKIIFYGVGGSATPAMDGAYKFTRLGF
TAMMLSDFHMMLPLVTNLKEGDIFVAISTSGRTKDVLEMAQYAKRQGATVIAITKLDQSSPLYKEADIRLCMPDVEQDHR
IASIASRMTQLNMIDALYVITFNRIGNKVLDQFMETREEALRLRKLK

Specific function: Represses The Expression Of The Hex Regulon (Zwf, Eda, Glp And Gap) (By Similarity). [C]

COG id: COG1737

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1788159, Length=274, Percent_Identity=31.021897810219, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1788767, Length=258, Percent_Identity=29.0697674418605, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI87082369, Length=243, Percent_Identity=28.8065843621399, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI87082130, Length=256, Percent_Identity=27.34375, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000281
- InterPro:   IPR001347
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01418 HTH_6; PF01380 SIS [H]

EC number: NA

Molecular weight: Translated: 31935; Mature: 31935

Theoretical pI: Translated: 7.41; Mature: 7.41

Prosite motif: PS51071 HTH_RPIR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKASTLLFKIESNMDQFSPAEKKVAIYIMENAEIVPNLTTKEVSTNAGASEASVVRFCKS
CCCCEEEEEEECCCCCCCCCCCEEEEEEEECCEECCCCCHHHCCCCCCCCHHHHHHHHHH
IGIGSFKAFKIALVRELTIADYNINDFSVMNTEDGPYDLFNKVTYVNKAAIEASVTAIDK
CCCCCHHHHEEEEEHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
KELEKAADRIVNADKIIFYGVGGSATPAMDGAYKFTRLGFTAMMLSDFHMMLPLVTNLKE
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDIFVAISTSGRTKDVLEMAQYAKRQGATVIAITKLDQSSPLYKEADIRLCMPDVEQDHR
CCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHH
IASIASRMTQLNMIDALYVITFNRIGNKVLDQFMETREEALRLRKLK
HHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKASTLLFKIESNMDQFSPAEKKVAIYIMENAEIVPNLTTKEVSTNAGASEASVVRFCKS
CCCCEEEEEEECCCCCCCCCCCEEEEEEEECCEECCCCCHHHCCCCCCCCHHHHHHHHHH
IGIGSFKAFKIALVRELTIADYNINDFSVMNTEDGPYDLFNKVTYVNKAAIEASVTAIDK
CCCCCHHHHEEEEEHEEEEEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
KELEKAADRIVNADKIIFYGVGGSATPAMDGAYKFTRLGFTAMMLSDFHMMLPLVTNLKE
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GDIFVAISTSGRTKDVLEMAQYAKRQGATVIAITKLDQSSPLYKEADIRLCMPDVEQDHR
CCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCEEECCCCCCHHH
IASIASRMTQLNMIDALYVITFNRIGNKVLDQFMETREEALRLRKLK
HHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]