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The map label for this gene is pdxA [H]

Identifier: 117921646

GI number: 117921646

Start: 3852649

End: 3853635

Strand: Direct

Name: pdxA [H]

Synonym: Shewana3_3208

Alternate gene names: 117921646

Gene position: 3852649-3853635 (Clockwise)

Preceding gene: 117921645

Following gene: 117921647

Centisome position: 77.48

GC content: 50.86

Gene sequence:

>987_bases
TTGACCACTAAACGTATTGCCGTTACCCCCGGAGAACCTGCGGGTATCGGCCCCGATTTAGTCGTGCAACTCGCTCAGCA
GGCTTGGCCTGCTGAGTTAGTCGTTTGTGCGGATCCCGAATTATTAGCCAGCCGAGCAAAACGACTCGGCCTGTCTGTTA
CTTTTCGCCCTTACCTGCCCGAGCAACCGCCTAAACCGCAGGAAGCAGGCACGCTCACCATTGCGCCTTTCAAACTGGTG
ACCGACGCCGTTTGCGGCCAGCTCGATGAGCAAAACAGTGCCTACGTAGTTGAAACCCTGCGTTATGCGGGTGAGAAAAA
CATGAGCGGCGAGTTTGATGCCGTGGTTACTGGCCCAGTCCATAAAGGGATCATCAACCAAGCGGGGATTTCCTTTAGCG
GCCATACCGAGTTTTTTGCCCATCAGGCCAACTGCCCCGATGTGGTCATGATGTTAGCGACTCAAGGTTTACAGGTGGCA
CTGGTGACCACCCATATTCCACTGGCCTATGTGGCAAAAGCCATTACGCGCCAGCGTTTGCATCATATTATTAAGATTTT
ACACGCTGATCTTATCAGCAAGTTTGCCATTGCTTCCCCTAAAATTTATGTCTGTGGCTTAAACCCACACGCGGGTGAAG
ACGGCCACCTTGGCCGGGAAGAAATCGATGTGATTATTCCGGCACTGAACGAACTGCGTGAAGAGTATCAAATGAACATT
GTCGGCCCTCTACCCGCCGATACCCTGTTCCAACCTAAATATTTACAGGACGCGGATGTCGTGTTGGCCATGTACCATGA
CCAAGGCTTACCCGTTCTAAAGTCACAGGGATTTGGCAAATCGGTAAACATTACCTTAGGTTTACCTTATATCCGTACCT
CGGTTGACCATGGTACGGCGCTCGATCTTGCGGGAACTGGCAAAGCCGATATTGGCAGTTTTGTCTGCGCCTTGAATAAA
GCCATTGAGTTATCCTCAAAAAACTAA

Upstream 100 bases:

>100_bases
TCGCAAATTTAATGAAGAACTGCAAAACTGGCTAGACGAAATGCGTGCCGACGCATACATTGAAGTCTTTCAGCCTGAGT
CAAACCGAGGTTAAGGTAAA

Downstream 100 bases:

>100_bases
ACGATTAGATATTAATGAGTAGCAAAGTACATTTAGGCCACACGGCCAGAAAGCGTTTCGGACAAAACTTTTTAACCGAC
GACAATGTGATTAACCGCAT

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MTTKRIAVTPGEPAGIGPDLVVQLAQQAWPAELVVCADPELLASRAKRLGLSVTFRPYLPEQPPKPQEAGTLTIAPFKLV
TDAVCGQLDEQNSAYVVETLRYAGEKNMSGEFDAVVTGPVHKGIINQAGISFSGHTEFFAHQANCPDVVMMLATQGLQVA
LVTTHIPLAYVAKAITRQRLHHIIKILHADLISKFAIASPKIYVCGLNPHAGEDGHLGREEIDVIIPALNELREEYQMNI
VGPLPADTLFQPKYLQDADVVLAMYHDQGLPVLKSQGFGKSVNITLGLPYIRTSVDHGTALDLAGTGKADIGSFVCALNK
AIELSSKN

Sequences:

>Translated_328_residues
MTTKRIAVTPGEPAGIGPDLVVQLAQQAWPAELVVCADPELLASRAKRLGLSVTFRPYLPEQPPKPQEAGTLTIAPFKLV
TDAVCGQLDEQNSAYVVETLRYAGEKNMSGEFDAVVTGPVHKGIINQAGISFSGHTEFFAHQANCPDVVMMLATQGLQVA
LVTTHIPLAYVAKAITRQRLHHIIKILHADLISKFAIASPKIYVCGLNPHAGEDGHLGREEIDVIIPALNELREEYQMNI
VGPLPADTLFQPKYLQDADVVLAMYHDQGLPVLKSQGFGKSVNITLGLPYIRTSVDHGTALDLAGTGKADIGSFVCALNK
AIELSSKN
>Mature_327_residues
TTKRIAVTPGEPAGIGPDLVVQLAQQAWPAELVVCADPELLASRAKRLGLSVTFRPYLPEQPPKPQEAGTLTIAPFKLVT
DAVCGQLDEQNSAYVVETLRYAGEKNMSGEFDAVVTGPVHKGIINQAGISFSGHTEFFAHQANCPDVVMMLATQGLQVAL
VTTHIPLAYVAKAITRQRLHHIIKILHADLISKFAIASPKIYVCGLNPHAGEDGHLGREEIDVIIPALNELREEYQMNIV
GPLPADTLFQPKYLQDADVVLAMYHDQGLPVLKSQGFGKSVNITLGLPYIRTSVDHGTALDLAGTGKADIGSFVCALNKA
IELSSKN

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=322, Percent_Identity=66.1490683229814, Blast_Score=434, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 35299; Mature: 35168

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKRIAVTPGEPAGIGPDLVVQLAQQAWPAELVVCADPELLASRAKRLGLSVTFRPYLP
CCCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCEEEECCCCC
EQPPKPQEAGTLTIAPFKLVTDAVCGQLDEQNSAYVVETLRYAGEKNMSGEFDAVVTGPV
CCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCH
HKGIINQAGISFSGHTEFFAHQANCPDVVMMLATQGLQVALVTTHIPLAYVAKAITRQRL
HHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHH
HHIIKILHADLISKFAIASPKIYVCGLNPHAGEDGHLGREEIDVIIPALNELREEYQMNI
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEE
VGPLPADTLFQPKYLQDADVVLAMYHDQGLPVLKSQGFGKSVNITLGLPYIRTSVDHGTA
ECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECCHHEECCCCCCE
LDLAGTGKADIGSFVCALNKAIELSSKN
EEECCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TTKRIAVTPGEPAGIGPDLVVQLAQQAWPAELVVCADPELLASRAKRLGLSVTFRPYLP
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCEEEECCCCC
EQPPKPQEAGTLTIAPFKLVTDAVCGQLDEQNSAYVVETLRYAGEKNMSGEFDAVVTGPV
CCCCCCCCCCEEEEEHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCH
HKGIINQAGISFSGHTEFFAHQANCPDVVMMLATQGLQVALVTTHIPLAYVAKAITRQRL
HHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHH
HHIIKILHADLISKFAIASPKIYVCGLNPHAGEDGHLGREEIDVIIPALNELREEYQMNI
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCEEE
VGPLPADTLFQPKYLQDADVVLAMYHDQGLPVLKSQGFGKSVNITLGLPYIRTSVDHGTA
ECCCCCCCCCCCCCCCCCCEEEEEEECCCCCEEECCCCCCEEEEEEECCHHEECCCCCCE
LDLAGTGKADIGSFVCALNKAIELSSKN
EEECCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]