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The map label for this gene is surA [H]

Identifier: 117921645

GI number: 117921645

Start: 3851338

End: 3852642

Strand: Direct

Name: surA [H]

Synonym: Shewana3_3207

Alternate gene names: 117921645

Gene position: 3851338-3852642 (Clockwise)

Preceding gene: 117921644

Following gene: 117921646

Centisome position: 77.46

GC content: 49.35

Gene sequence:

>1305_bases
ATGAAACCCAGTAAACATCTGATTTTTGCTTTATTTGCACTCGCTATCAGCCAGCCTACTATGGCCGCTCCCCAGCCAAT
CGACCGTGTTGCCGTTCAAATCAACGACGGTATTGTGCTCGAAAGTGAAATCACCAACATGATTGACACTGTAAAAGCCA
ATGCGAGAGCCGCGAATCAATCGTTGCCATCCGACAGTGCACTGCGTACTCAGGTTATCGAGCGACTCATCCTCACCCGT
TTGCAGTTGCAGATGGCGGATCGTATCGGTCTGCATATCGGTGACTTACAGCTAGACCAAGCAATTGAAAACATTGCCCG
CGAGCAAAAAATGACCGTGGCGCAAATGCAGCAAAAAATCGAGAGCGAAGGCTTAAGCTTCAGCCAGTACCGTGAGCAAC
TGCGTGAAGAAATCACCCTAGGTGAAATTCAACGTATCCAAGTACAACGCCGTATCCAAGTGTCACCACAGGAAATCACC
GGCCTAGTAAAACTGATCCAAGAGCAAGGTATGAAGGACGTCGAATACCAAATCGGCCATATCCTGATTGACGTACCGAA
CAACCCAAGCAGTGAACAGCTGGAAGCCTCGAGCAAGCGCGCGAACGCCGTACTCGAGCGTTTAAAGAGTGGTGAGGATT
TCCGCCGCACCGCCATCGCCTCTTCATCGGGTCCTAAGGCGCTGGAAGGCGGTATCTGGGATTACATGAACATCAACGAG
ATGCCAACGCTATTTGCGGAAGTCATCAACGGTGCGAAGAAAGGCGACATTATCGGCCCAATCAAGAGTGGCGCAGGTTT
CCATATCATCAAGATCATGGATGCCCGTGGTTTACAAACCAAAGAAATTGAAGAAGTCAGAGCACGTCATATCCTGCTCA
AGCCATCGCCAATTCTGTCGGAAGACCGCGCTAAGGCCATGTTGGAACAGTTCTTAAAGCAAATTCGCTCTGGCGAAGCC
AAGTTTGAAGATTTAGCCCGTCAGTATTCTGAAGATCCAGGTTCAGCCACTAAAGGTGGTGAACTGGGCTGGGCAGAGCC
AAGCATTTATGTGCCTGAATTTGCGCAAACCCTTAACAGCTTAAGCCCAGATCAAATCAGTGAGCCTTTCCGTACTACCC
ACGGCTGGCATATCACTCAGCTGGAAGAGCGCAGAAAAACCGATGCCACGGATCAATTTAATACCAACCGTGCGCACCAA
CTGATCTTCCGTCGCAAATTTAATGAAGAACTGCAAAACTGGCTAGACGAAATGCGTGCCGACGCATACATTGAAGTCTT
TCAGCCTGAGTCAAACCGAGGTTAA

Upstream 100 bases:

>100_bases
AAGAACATTTAGGCAACTCACTGTAATTTCGATATAAATGGTAAAGTTAACTTAAATAAGCCGTCGAATTTGACCTTAGA
ACGTGCCAAGGATTTTGTGG

Downstream 100 bases:

>100_bases
GGTAAATTGACCACTAAACGTATTGCCGTTACCCCCGGAGAACCTGCGGGTATCGGCCCCGATTTAGTCGTGCAACTCGC
TCAGCAGGCTTGGCCTGCTG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQSLPSDSALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKIESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEIT
GLVKLIQEQGMKDVEYQIGHILIDVPNNPSSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
MPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEA
KFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLSPDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQ
LIFRRKFNEELQNWLDEMRADAYIEVFQPESNRG

Sequences:

>Translated_434_residues
MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQSLPSDSALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKIESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEIT
GLVKLIQEQGMKDVEYQIGHILIDVPNNPSSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
MPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEA
KFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLSPDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQ
LIFRRKFNEELQNWLDEMRADAYIEVFQPESNRG
>Mature_434_residues
MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQSLPSDSALRTQVIERLILTR
LQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKIESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEIT
GLVKLIQEQGMKDVEYQIGHILIDVPNNPSSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
MPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILSEDRAKAMLEQFLKQIRSGEA
KFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNSLSPDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQ
LIFRRKFNEELQNWLDEMRADAYIEVFQPESNRG

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=429, Percent_Identity=42.6573426573427, Blast_Score=370, Evalue=1e-104,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48972; Mature: 48972

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQ
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCEEEHHHHHHHHHHHHHHHHHHHC
SLPSDSALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEITGLVKLIQEQGMKDVEYQIGH
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHEEECE
ILIDVPNNPSSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCH
MPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILS
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEECCCCCCC
EDRAKAMLEQFLKQIRSGEAKFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
LSPDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQLIFRRKFNEELQNWLDEMRA
CCCHHHCCCHHHCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DAYIEVFQPESNRG
CCEEEEECCCCCCC
>Mature Secondary Structure
MKPSKHLIFALFALAISQPTMAAPQPIDRVAVQINDGIVLESEITNMIDTVKANARAANQ
CCCCHHHHHHHHHHHHCCCCCCCCCCHHHEEEEECCCEEEHHHHHHHHHHHHHHHHHHHC
SLPSDSALRTQVIERLILTRLQLQMADRIGLHIGDLQLDQAIENIAREQKMTVAQMQQKI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEECHHHHHHHHHHHHHHHHHHHHHHHHHH
ESEGLSFSQYREQLREEITLGEIQRIQVQRRIQVSPQEITGLVKLIQEQGMKDVEYQIGH
HHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHEEECE
ILIDVPNNPSSEQLEASSKRANAVLERLKSGEDFRRTAIASSSGPKALEGGIWDYMNINE
EEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCCCCCCCCCCH
MPTLFAEVINGAKKGDIIGPIKSGAGFHIIKIMDARGLQTKEIEEVRARHILLKPSPILS
HHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHEEEECCCCCCC
EDRAKAMLEQFLKQIRSGEAKFEDLARQYSEDPGSATKGGELGWAEPSIYVPEFAQTLNS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCC
LSPDQISEPFRTTHGWHITQLEERRKTDATDQFNTNRAHQLIFRRKFNEELQNWLDEMRA
CCCHHHCCCHHHCCCEEEHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
DAYIEVFQPESNRG
CCEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]